From Epiphylogenesis to General Organology by Robert Alexander Gorny, Andrej Radman

“… Epiphylogenesis is a neologism coined under Stiegler’s anthropotechnical theorisation of the co-evolution of brains and tools. In line with feminist and decolonial theorists like Claire Colebrook and Kathryn Yusoff, it foregrounds that there has never been such a thing as ‘the human’. …”
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Information and knowledge: an evolutionary framework for information science by Marcia J. Bates

“…The approach is rooted in an evolutionary framework; that is, modes of information perception, processing, transmission, and storage are seen to have developed as a part of the general evolution of members of the animal kingdom. Brains are expensive for animals to support; consequently, efficient storage, including, particularly, storage at emergent levels-for example, storing the concept of chair, rather than specific memories of all chairs ever seen, is powerful and effective for animals. …”
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Association of p53 with Neurodegeneration in Parkinson’s Disease by Qiang Luo, Wei Sun, Yi-Fan Wang, Ji Li, Da-Wei Li

“…Recent studies have revealed that p53 levels and activity are substantially increased in affected neurons in cellular and animal models of Parkinson’s disease (PD) as well as in the brains of PD patients. p53 activation in response to neurodegenerative stress is closely associated with the degeneration of dopaminergic neurons accompanied by mitochondrial dysfunction, reactive oxygen species (ROS) production, abnormal protein aggregation, and impairment of autophagy, and these pathogenic events have been implicated in the pathogenesis of PD. …”
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Skin Matters: Identifying Pain Mechanisms and Predicting Treatment Outcomes by Edward A. Shipton

“…The somatosensory neurons that innervate our skin constantly update our brains on the objects and environmental factors that surround us. …”
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Dendrites endow artificial neural networks with accurate, robust and parameter-efficient learning by Spyridon Chavlis, Panayiota Poirazi

“…However, unlike biological brains who tackle similar problems in a very efficient manner, DL algorithms require a large number of trainable parameters, making them energy-intensive and prone to overfitting. …”
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Drosophila Torsin Protein Regulates Motor Control and Stress Sensitivity and Forms a Complex with Fragile-X Mental Retardation Protein by Phuong Nguyen, Jong Bok Seo, Hyo-Min Ahn, Young Ho Koh

“…One important biochemical consequence of DTor-RNAi expression in fly brains was upregulation of alcohol dehydrogenase (ADH). …”
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Cerebral hypoperfusion reduces tau accumulation by Ghupurjan Gheni, Mitsuru Shinohara, Masami Masuda‐Suzukake, Akihiko Shindo, Atsushi Watanabe, Kaori Kawai, Guojun Bu, Hidekazu Tomimoto, Masato Hasegawa, Naoyuki Sato

“…The research was carried out using clinical and neuropathological data collected from the National Alzheimer's Coordinating Center (NACC) database and an animal model in which bilateral common carotid artery stenosis surgery was performed, following the injection of tau seeds into the brains of wild‐type mice. Results Analysis of the NACC database suggests that clinical stroke history and lacunar infarcts are associated with lower neurofibrillary tangle pathology. …”
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Mathematics as Information Compression via the Matching and Unification of Patterns by J. Gerard Wolff

“…This new perspective on the foundations of mathematics reflects the facts that mathematics is almost exclusively the product of human brains, and has been developed, as an aid to human thinking, mathematics is likely to be consonant with much evidence for the importance of IC in human learning, perception, and cognition. …”
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The role of insulin signaling with FOXO and FOXK transcription factors by Masaji Sakaguchi

“…Throughout the evolution of metazoan animals and the development of their brains, a sustainable energy supply has been essential to overcoming the competition for survival under various environmental stresses. …”
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Neuroprotective Effects of Bone Marrow Mesenchymal Stem Cells on Bilateral Common Carotid Arteries Occlusion Model of Cerebral Ischemia in Rat by Bagher Pourheydar, Sara Soleimani Asl, Mostafa Azimzadeh, Adel Rezaei Moghadam, Asghar Marzban, Mehdi Mehdizadeh

“…We performed neuromuscular and vestibulomotor function tests to assess behavioral function and, finally, brains were subjected to hematoxylin and eosin (H&E), anti-Brdu immunohistochemistry, and TUNEL staining. …”
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Effects of Level of Retrieval Success on Recall-Related Frontal and Medial Temporal Lobe Activations by Daniela Montaldi, Andrew R. Mayes, Anna Barnes, Donald M. Hadley, Jim Patterson, David J. Wyper

“…Brain dedicated single photon emission computed tomography (SPECT) was used to compare the neuroactivation produced by the cued recall of response words in a set of studied word pairs with that produced by the cued retrieval of words semantically related to unstudied stimulus words. …”
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Unraveling the Effect of Immunogenicity on the PK/PD, Efficacy, and Safety of Therapeutic Proteins by Alison Smith, Hugh Manoli, Stacey Jaw, Kimberley Frutoz, Alan L. Epstein, Leslie A. Khawli, Frank-Peter Theil

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Second-generation anti-amyloid monoclonal antibodies for Alzheimer’s disease: current landscape and future perspectives by Byeong-Hyeon Kim, Sujin Kim, Yunkwon Nam, Yong Ho Park, Seong Min Shin, Minho Moon

“…Specifically, based on their efficacy in removing Aβ plaques from the brains of patients with AD, the U.S. Food and Drug Administration has approved three anti-amyloid MABs, aducanumab (Aduhelm®), lecanemab (Leqembi®), and donanemab (Kisunla™). …”
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iPSC-Derived Retinal Pigment Epithelium Allografts Do Not Elicit Detrimental Effects in Rats: A Follow-Up Study by Peter D. Westenskow, Felicitas Bucher, Stephen Bravo, Toshihide Kurihara, Daniel Feitelberg, Liliana P. Paris, Edith Aguilar, Jonathan H. Lin, Martin Friedlander

“…We observed no gross abnormalities in the eyes, livers, spleens, brains, and blood in aging rats with iPSC-RPE grafts. iPS-RPE cells that integrated into the subretinal space outlived the photoreceptors and survived for as long as 2 1/2 years while nonintegrating RPE cells were ingested by host macrophages. …”
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Neuroprotective effects of curculigoside against Alzheimer’s disease via regulation oxidative stress mediated mitochondrial dysfunction in L-Glu-exposed HT22 cells and APP/PS1 mice... by Wenqi Wang, Yidi Qu, Siyu Li, Jinyu Chu, Hongxin Yang, Lirong Teng, Di Wang

“…In APP/PS1 mice, 4-week CCG administration significantly improved their memory and behavioral impairments, enhanced the function of cholinergic system, reduced the deposition of Aβ and neurofibrillary fiber tangles caused by tau phosphorylation, and suppressed the development and progression of oxidative stress in brains of APP/PS1 mice. Based on the screening of proteomic analysis on hippocampus, CCG were confirmed that it could regulate the expression levels of proteins related to mitochondrial dysfunction, mainly through activating on AMPK/Nrf2 signaling, in APP/PS1 mice and L-Glu-exposed HT22 cells. …”
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Effect of Lipopolysaccharide and TNFα on Neuronal Ascorbic Acid Uptake by Veedamali S. Subramanian, Trevor Teafatiller, Anshu Agrawal, Masashi Kitazawa, Jonathan S. Marchant

“…In vivo exposure to LPS or TNFα also decreased SVCT2 protein and mRNA levels in mouse brains. Both LPS and TNFα decreased SLC23A2 promoter activity. …”
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Acute macular neuroretinopathy occurrence in a Behçet disease patient: a case report by Ayman Mabchour, Moncef Ould Hamou, Simon Correa, François Willermain, Nacima Kisma

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Vitrification affects the post-implantation development of mouse embryos by inducing DNA damage and epigenetic modifications by Yurong Chen, Haibo Zhu, Fucheng Guo, Luyao Wang, Wenli Zhang, Ruizhi Liu, Xiaoling Zhang, Xiangpeng Dai

“…Moreover, vitrification significantly altered transcriptome profiles of mice placentas and brains at embryonic day 18.5 (E18.5). Thus, vitrification exhibited a long-term effect on mouse embryo viability by increasing ROS levels, DNA damage, altering the epigenetic modifications and transcriptome profiles.…”
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Association between BDNF rs6265 and Obesity in the Boston Puerto Rican Health Study by Xian-Yong Ma, Wei Qiao Qiu, Caren E. Smith, Laurence D. Parnell, Zong-Yong Jiang, Jose M. Ordovas, Katherine L. Tucker, Chao-Qiang Lai

“…Brain-derived neurotrophic factor (BDNF) has been associated with regulation of body weight and appetite. …”
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Isoforsythiaside confers neuroprotection against Alzheimer’s disease by attenuating ferroptosis and neuroinflammation in vivo and in vitro by Chunyue Wang, Hongbo Jiang, Honghan Liu, Shanshan Chen, Hangyu Guo, Shuoshuo Ma, Weiwei Han, Yu Li, Di Wang

“…Additionally, IFY upregulated the expression levels of GPX4, FTH, FTL, p-GSK-3β, Nrf2, and NQO1, and downregulated the expression of TFR1, DMT1, p-Fyn, GFAP, p-IKKα+β, p-IκBα, p-NF-κB, and pro-inflammatory factors in the brains of APP/PS1 mice and erastin-damaged HT22 cells. …”
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