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5221
Association of valproate use and hippocampal atrophy in idiopathic generalized epilepsy
Published 2025-01-01“…Objective: Recent studies revealed the effect of valproate (VPA) on brain structural changes in idiopathic generalized epilepsy (IGE). …”
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5222
Increasing the resolution of ECG and EEG mapping equipment using nanosensors
Published 2023-02-01“…The problem of a large number of people with cardiovascular diseases and brain diseases is relevant all over the world. The problem of mortality and the consequences of these diseases is particularly acute. …”
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5223
Bioinformatics insights into mitochondrial and immune gene regulation in Alzheimer's disease
Published 2025-02-01“…In addition, single-gene enrichment analysis revealed that NDUFAB1 was significantly enriched in pathways associated with diseases, such as Alzheimer's and Parkinson's, providing valuable insights for future clinical research on Alzheimer's in the context of mitochondrial–immune interactions. Interestingly, brain tissue pathology showed neuronal atrophy and demyelination in AD mice, along with a reduction in Nissl bodies. …”
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5224
Association of player position and functional connectivity alterations in collegiate American football players: an fMRI study
Published 2025-01-01“…IntroductionResting state-fMRI, provides a sensitive method for detecting changes in brain functional integrity, both with respect to regional oxygenated blood flow and whole network connectivity. …”
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5225
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5226
Refining management strategies for Lennox–Gastaut syndrome: Updated algorithms and practical approaches
Published 2025-02-01“…It is characterized by a variety of different types of seizures (abnormal electrical activity in the brain), which are difficult to treat and often cause people with the condition to fall and injure themselves. …”
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5227
Neuroprotective Potential of <i>Origanum majorana</i> L. Essential Oil Against Scopolamine-Induced Memory Deficits and Oxidative Stress in a Zebrafish Model
Published 2025-01-01“…We also investigated acetylcholinesterase (AChE) activity and the brain’s oxidative stress status. In parallel, we performed in silico predictions (research conducted using computational models) of the pharmacokinetic properties of the main compounds identified in OmEO, using platforms such as SwissADME, pKCSM, ADMETlab 2.0, and ProTox-II. …”
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5228
Comprehensive analysis of the 5-HTTLPR allelic polymorphism effect on behavioral and neurophysiological indicators of executive control in people from different ethnic groups in Si...
Published 2021-09-01“…The amplitude of the premotor peak of the evoked brain potential was used as a neurophysiological marker of the person’s readiness to the execution of target-directed activity. …”
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5229
Ivermectin as a promising therapeutic option for onchocerciasis‐associated epilepsy
Published 2025-02-01“…Research shows that ivermectin not only targets the parasitic cause of the disease but may also help reduce brain inflammation, which plays a key role in epilepsy. …”
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5230
Improved Outcomes following the Establishment of a Neurocritical Care Unit in Saudi Arabia
Published 2018-01-01“…Dedicated neurocritical care units have dramatically improved the management and outcome following brain injury worldwide. Aim. This is the first study in the Middle East to evaluate the clinical impact of a neurocritical care unit (NCCU) launched within the diverse clinical setting of a polyvalent intensive care unit (ICU). …”
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5231
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5232
Dye-based fluorescent organic nanoparticles made from polar and polarizable chromophores for bioimaging purposes: a bottom-up approach
Published 2024-04-01“…Thanks to these unique properties, these dFONs could be imaged and tracked up to 150 µm deep in brain tissue.…”
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5233
A novel method for detecting intracranial pressure changes by monitoring cerebral perfusion via electrical impedance tomography
Published 2025-01-01“…Methods An intracranial hypertension model was prepared by injecting autologous un-anticoagulated blood into the brain parenchyma of twelve Landrace swine. Invasive ICP monitoring was used as a control method, and a high-precision EIT system was used to acquire and analyze the changing patterns of cerebral perfusion EIT image parameters with respect to ICP. …”
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5235
Mind wandering enhances statistical learning
Published 2025-02-01“…Summary: The human brain spends 30–50% of its waking hours engaged in mind-wandering (MW), a common phenomenon in which individuals either spontaneously or deliberately shift their attention away from external tasks to task-unrelated internal thoughts. …”
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5236
Food nutrition and toxicology targeting on specific organs in the era of single-cell sequencing
Published 2024-01-01“…ScRNA-seq applications has been summarized on three typical organs (brain, liver, kidney), and two representative immune- and tumor related health problems. …”
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5237
Targeting natural antioxidant polyphenols to protect neuroinflammation and neurodegenerative diseases: a comprehensive review
Published 2025-01-01“…This review emphasizes the growing body of evidence supporting the therapeutic potential of polyphenols in combating neurodegeneration and neuroinflammation, as well as enhancing brain health. Despite the substantial evidence and promising hypotheses, further research and clinical investigations are necessary to fully understand the role of polyphenols and establish them as advanced therapeutic targets for age-related neurodegenerative diseases and neuroinflammatory conditions.…”
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5238
The relationship between thiamin, folic acid and cognitive function in a rat model of uremia
Published 2024-12-01“…The Morris water maze was used to assess the cognitive function eight weeks post-surgery, and serum levels of thiamin, folic acid and homocysteine were detected subsequently. Brain and kidney tissues were collected for pathological examination and 8-Hydroxy-2’-deoxyguanosine (8-OHdG) immunochemistry staining. …”
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5239
Relationship between cognitive impairment and hippocampal iron overload: A quantitative susceptibility mapping study of a rat model
Published 2025-02-01“…QSM could be used to quantify brain iron overload in vivo, highlighting its potential clinical application for assessing cognitive impairment in patients with thalassemia.…”
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5240