Astrocyte-Derived Interleukin 11 Modulates Astrocyte–Microglia Crosstalk via Nuclear Factor-κB Signaling Pathway in Sepsis-Associated Encephalopathy by Dandan Zhu, Peng Wang, Xiyue Chen, Kaituo Wang, Yunsong Wu, Min Zhang, Jianhua Qin

“…Intriguingly, we found that IL11 addition markedly rescued LPS-induced neuronal injuries on the microfluidic system and brain injury in the SAE mouse model. This study defines an unknown crosstalk of astrocyte–microglia mediated by IL11, which contributed to the neuropathogenesis of SAE, and suggested a potential therapeutic value of IL11 in the devastating disease.…”
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Association between transarterial chemoembolization refractoriness and prognosis in Chinese patients with hepatocellular carcinoma: a large retrospective cohort study by Qinxue Sun, Ziliang Wu, Xi Yin, Feng Li, Ri Liu

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MicroRNA-147a Targets SLC40A1 to Induce Ferroptosis in Human Glioblastoma by Peng Xu, Fei-Hang Ge, Wen-Xin Li, Zhen Xu, Xue-Li Wang, Jing-Lan Shen, Ai-Bo Xu, Rong-Rong Hao

“…Glioblastoma is one of the most common malignant tumors in the brain, and these glioblastoma patients have very poor prognosis. …”
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MicroRNAs-Proteomic Networks Characterizing Human Medulloblastoma-SLCs by Giuseppina Catanzaro, Zein Mersini Besharat, Neha Garg, Maurizio Ronci, Luisa Pieroni, Evelina Miele, Angela Mastronuzzi, Andrea Carai, Vincenzo Alfano, Agnese Po, Isabella Screpanti, Franco Locatelli, Andrea Urbani, Elisabetta Ferretti

“…Medulloblastoma (MB) is the most common malignant brain tumor of pediatric age and is characterized by cells expressing stem, astroglial, and neuronal markers. …”
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Synthesis and Characterization of Paclitaxel-Loaded Silver Nanoparticles: Evaluation of Cytotoxic Effects and Antimicrobial Activity by Tutku Tunç, Ceylan Hepokur, Afşin Kari̇per

“…We investigated the antiproliferative activities of silver nanoparticles synthesized by adding paclitaxel on MCF-7 (breast adenocarcinoma cell line), A549 (lung carcinoma cell line), C6 (brain glioma cell line) cells, and healthy WI-38 (fibroblast normal cell line) cell lines and their antimicrobial activities on 10 different microorganisms. …”
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Clinical application of 3D slicer reconstruction and 3D printing localization combined with neuroendoscopy technology in VPS surgery by Long Zhou, Pan Lei, Ping Song, Zhiyang Li, Huikai Zhang, Hangyu Wei, Lun Gao, Qiuwei Hua, Hui Ye, Qianxue Chen, Silei Zhang, Qiang Cai

“…The drainage tube position was confirmed by brain CT and 3D Slicer reconstruction after operation, of which 30 cases were located in the frontal horn or center of the ipsilateral lateral ventricle, and 3 cases were located in the frontal horn or center of the contralateral lateral ventricle. …”
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Steroid use for established bronchopulmonary dysplasia: study protocol for a systematic review and meta-analysis by Roy K Philip, Joanna Seliga-Siwecka, Eduardo Villamor, Maria Pierro, Niazy Al Assaf, Sabina Strashun, Roberto Chioma, Kinga Zielińska, Krzysztof Włodarczyk

“…Moreover, a late timing for steroid treatment may show a more favourable safety profile in terms of neurodevelopment outcomes, considering the added postnatal brain maturation of these infants. Here, we report a protocol for a systematic review, which aims to determine the efficacy and long-term safety of postnatal steroids for the treatment of established BPD in preterm infants.Methods and analysis MEDLINE, Embase, Cochrane databases and sources of grey literature for conference abstracts and trial registrations will be searched with no time or language restriction. …”
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Chest CT Scan Features to Predict COVID-19 Patients’ Outcome and Survival by Mohammad-Mehdi Mehrabi Nejad, Aminreza Abkhoo, Faeze Salahshour, Mohammadreza Salehi, Masoumeh Gity, Hamidreza Komaki, Shahriar Kolahi

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Cross-sectional study on the association between neutrophil-percentage-to-albumin ratio (NPAR) and prevalence of stroke among US adults: NHANES 1999–2018 by Chenglin Ye, Yong Mo, Tiansheng Su, Guangxiang Huang, Jiachao Lu, Shuling Tang, Qianrong Huang, Qiuyun Li, Qian Jiang, Fangzhou Guo, Pinghua Wu, Guozhong Zhang, Jun Yan

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Switchable Adhesion of Hydrogels to Plant and Animal Tissues by Leah K. Borden, Morine G. Nader, Faraz A. Burni, Samantha M. Grasso, Irene Orueta‐Ortega, Mahima Srivastava, Paula Montero‐Atienza, Metecan Erdi, Sarah L. Wright, Rajabrata Sarkar, Anthony D. Sandler, Srinivasa R. Raghavan

“…., arteries, muscles, and cornea), but not others (e.g., adipose, brain). Tissues with anisotropic structure show anisotropic adhesion strength by EA. …”
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Studying Alzheimer’s disease through an integrative serum metabolomic and lipoproteomic approach by Alessia Vignoli, Giovanni Bellomo, Federico Paolini Paoletti, Claudio Luchinat, Leonardo Tenori, Lucilla Parnetti

“…We hypothesize that metabolic alterations present at the level of the brain could be reflected at a systemic level in blood serum of patients, and that these alterations could be used as prognostic biomarkers. …”
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Conversational Therapy through Semi-Immersive Virtual Reality Environments for Language Recovery and Psychological Well-Being in Post Stroke Aphasia by A. Giachero, M. Calati, L. Pia, L. La Vista, M. Molo, C. Rugiero, C. Fornaro, P. Marangolo

“…Aphasia is a highly disabling acquired language disorder generally caused by a left-lateralized brain damage. Even if traditional therapies have been shown to induce an adequate clinical improvement, a large percentage of patients are left with some degree of language impairments. …”
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Nano-curcumin Effects on Ischemic Stroke clinical outcomes and Interleukin-6 Levels: Pilot Randomized Clinical Trial by Zeinab Ehtiatkar, Alia Saberi, Samaneh Ghorbani Shirkouhi, Mozaffar Hosseininezhad, Shahrokh Yousefzadeh-Chabok, Yaser Moadabi, Ashkan Karimi, Haniyeh Shadrou Gharani, Sasan Andalib

“…Background: Accumulation of inflammatory factors in the stroke area results in brain tissue damage and a patient’s disability. It has been demonstrated that curcumin has neuroprotective effects. …”
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Glutamine-glutamate centered metabolism as the potential therapeutic target against Japanese encephalitis virus-induced encephalitis by Mengyuan Li, Hang Yuan, Xiaofei Yang, Yingfeng Lei, Jianqi Lian

“…Methods Metabolomics analysis was performed to comprehensively delineate the metabolic profiles in JEV-infected mice brains and neurons. Metabolic flux analysis, quantitative real-time PCR, western blotting and fluorescence immunohistochemistry were utilized to describe detailed glutamine-glutamate metabolic profiles during JEV infection. …”
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Post-Marketing Pharmacovigilance of Canakinumab from the FDA Adverse Event Reporting System (FAERS) by Weidong Zhang, Yunzhou Chen, Zeyu Yao, Mengling Ouyang, Minghui Sun, Shupeng Zou

“…Among these, 19 preferred terms (PTs) were identified as unexpected signals, including deafness, appendicitis, brain oedema, cushingoid, cellulitis, and papilledema. …”
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Lung Cancer with Skin and Breast Metastasis: A Case Report and Literature Review by Bikash Bhattarai, Marie Frances Schmidt, Meenakshi Ghosh, Abhisekh Sinha Ray, Saveena Manhas, Vikram Oke, Chidozie Charles Agu, Md. Rawshan Basunia, Danilo Enriquez, Joseph Quist, Catherine Bianchi, Ravi Hans, Saroj Kandel

“…Frequent sites of metastasis include the Hilar lymph nodes, adrenal glands, liver, brain, and bone. The following case report is of a primary lung cancer with metastases to the breast and skin. …”
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Clinical Characteristics of Visual Dysfunction in Carbon Monoxide Poisoning Patients by Wei-Kang Bi, Jin-Lin Wang, Xu-Dong Zhou, Ze-Kun Li, Wen-Wen Jiang, Shao-Bin Zhang, Yong Zou, Ming-Jun Bi, Qin Li

“…The clinical characteristics of visual dysfunction in patients with CO poisoning were analyzed through the collection of medical history, regular physical examination, brain magnetic resonance imaging (MRI), ophthalmological examination, the National Eye Institute Visual Function Questionnaire (NEI-VFQ), and its influencing factors. …”
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Unlocking the full potential of resistance training: a comparative analysis of low- and high-intensity effects on neurotrophic growth factors and homocysteine by Chongwen Zuo, Yi Yin, Zhiyang Zheng, Ren Mu, Yuxin Liang, Shan Wang, Chaoqun Ye

“…Blood samples were collected at three time points: pre-training, post training, and after 30 min of rest to measure changes in serum lactate, serum brain-derived neurotrophic factor (BDNF), insulin-like growth factor 1 (IGF-1), vascular endothelial growth factor (VEGF), irisin, and plasma homocysteine (Hcy) levels. …”
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Sleep quality among sample of Egyptian patients with Alzheimer’s disease: risk factors and role of genetic profiling for ACE, ACE 2 and APO E genotypes by Khaled Ahmed Elbeh, Mohamed Abdala Abbas, Mohammed H. Hassan, Mohamed Moslem Hefny, Shimaa Fathy Sakr, Reham Bakry Mohamed, Mahmoud Ahmed Bekiet, Tarek Desoky

“…Abstract Background Most individuals having Alzheimer’s disease generally experience increased frequency of awakenings as well as prolonged wakefulness periods at night. Brain wave research indicate reductions in both REM (dreaming stage) along with NREM (non-dreaming stage). …”
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Molecular Mechanisms Underlying Neuroinflammation Intervention with Medicinal Plants: A Critical and Narrative Review of the Current Literature by Sandra Maria Barbalho, Beatriz Leme Boaro, Jéssica da Silva Camarinha Oliveira, Jiří Patočka, Caroline Barbalho Lamas, Masaru Tanaka, Lucas Fornari Laurindo

“…Neuroinflammation is a key factor in the progression of neurodegenerative diseases, driven by the dysregulation of molecular pathways and activation of the brain’s immune system, resulting in the release of pro-inflammatory and oxidative molecules. …”
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