Migration, Distribution, and Safety Evaluation of Specific Phenotypic and Functional Mouse Spleen-Derived Invariant Natural Killer T2 Cells after Adoptive Infusion by Dongzhi Chen, Wenbin Xu, Jingfang Teng, Huifang Liu, Yuanyuan Wang, Yan Wang, Shujie Cheng, Ming Meng

“…After dissecting the mice, it was found that there were no significant abnormalities in the relevant immune organs, brain, heart, kidney, lung, and other organs. Intraperitoneal injection of α-GalCer results in a large number of iNKT2 cells, mainly secreting anti-inflammatory cytokine IL-4, from the spleen of mice. …”
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A comparison between the effect of Oral Melatonin and Hydroxyzine for preventing preoperative Anxiety in Pediatric Patients undergoing Adenotonsillectomy: A randomized, double-blin... by Sarah Omar Mousa, Amany Khairy Abo El Hussien, Gehad Hanafy Abdalgaliel

“…Hydroxyzine is a first-generation antihistaminic that crosses the blood-brain barrier, causing sedation. Objectives: Our study aimed to estimate the effect of a single preoperative oral melatonin versus hydroxyzine to prevent preoperative pediatric anxiety in adenotonsillectomy children. …”
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Modeling the modulation of beta oscillations in the basal ganglia by dual-target optogenetic stimulation by Xiaomin Wang, Ying Yu, Qingyun Wang

“…Optogenetic techniques provide precise control over the activity of specific neurons within the nucleus, offering more accurate regulatory effects compared to deep brain stimulation. The heterogeneity of the globus pallidus externa (GPe) has garnered wide attention, wherein significant differences in pathological changes emphasize its potential as a stimulation target with distinct mechanisms. …”
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Learning Dendritic-Neuron-Based Motion Detection for RGB Images: A Biomimetic Approach by Tianqi Chen, Yuki Todo, Zhiyu Qiu, Yuxiao Hua, Delai Qiu, Xugang Wang, Zheng Tang

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ادمان شبکة الانترنت وأضرارها الصحیة والنفسیة والاجتماعیة على طلاب المدارس الثانویة بمدینة شبین الکوم بمحافظة المنوفیة... by د. میرفت مفید عبد الستار

“…The most important results and recommendationsreached by the researcher through the field study in public secondary schools inShebin El-Kom city, Monofiya governorate, Egypt.The Results of the studyThe researcher reached many results as follows:-1. 1-The main causes of addiction to the students of secondary education forthe Internet Monofiya, the following respectively: entertainment and play,lack of control parents to me, a sense of vacuum time, ease of dealingwith others through the Internet, sense of comfort while using the Internet,to escape from the responsibility to study and study, not My interest onthe part of the family and the community around me, to escape from myproblems surrounding the family, rather than going out2. 2- The largest percentage of students addicted to the Internet in the agegroup of 16 years reached 102 respondents, representing 56.7% of thetotal male and female population in the study sample.3. .3- The most important negative aspects of the internet came between hisstudents and secondary education students in Monofiya, respectively:lack of supervision, porn sites, addiction to sit for long periods, violation ofrights, falling into unknown relationships, exposure to fraud and fraud.4. 4- came the most important health damage caused by Internet addictionamong education students secondary Monofiya: pain the eyes of the mostdifficult and the most first health damage caused by the use of the Internetamong students at a percentage of 60.5%, followed by insomnia andsleep deprivation, a percentage of 50.4%, followed by fatigue and fatigueby 49.7 %, mother bone by 45.7%, and diseases of the brain and nerves30.2%, heart disease by 22.7%, and finally skin diseases by 21.5% of thetotal sample.…”
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Leaflet: Operative Steps for Interventional Studies in Neuroscience by Maria Meringolo, Sergio Delle Monache, Giuseppina Martella, Antonella Peppe

“…Notably, neuroscience drug development encounters distinct challenges, including the complex nature of diseases, limitations imposed by the blood–brain barrier, the absence of reliable predictive preclinical models, and regulatory hurdles. …”
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Case Report: Rare cardiovascular characteristics of tuberous sclerosis complex with novel TSC2 variant by Zhiqin Du, Xiao Ma, Xiao Ma, Xiao Ma, Jianhua Li, Fang Yang, Yangfan Guo, Yangfan Guo

“…Cardiovascular characteristics included a history of heart valve disease, a bicuspid aortic valve, and severe aortic regurgitation. multi-system characteristics of TSC were also presented, affecting skin, brain, lung, kidney, and bone. She underwent aortic valve replacement but experienced postoperative complications, including significant pleural and pericardial effusions requiring drainage and subsequent thoracic duct ligation.ConclusionThis case expands the clinical spectrum of TSC-associated cardiovascular abnormalities, highlighting the rare association of BAV with this disorder. …”
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Administration of Recombinant Heat Shock Protein 70 Delays Peripheral Muscle Denervation in the SOD1G93A Mouse Model of Amyotrophic Lateral Sclerosis by David J. Gifondorwa, Ramon Jimenz-Moreno, Crystal D. Hayes, Hesam Rouhani, Mac B. Robinson, Jane L. Strupe, James Caress, Carol Milligan

“…The exogenous rhHsp70 was localized to the muscle and not to spinal cord or brain suggesting it modulates peripheral pathophysiology. …”
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The gut microbiota‐derived metabolite indole‐3‐propionic acid enhances leptin sensitivity by targeting STAT3 against diet‐induced obesity by Zhiwei Wang, Shaying Yang, Liangju Liu, Aiqin Mao, Hao Kan, Fan Yu, Xin Ma, Lei Feng, Tingting Zhou

“…Our study suggests that the IPA‐based gut‐brain axis regulates host metabolism, and supplementation with microbiome‐derived IPA could be a promising intervention strategy for treating obesity.…”
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A software system for modeling evolution in a population of organisms with vision, interacting with each other in 3D simulator by A. P. Devyaterikov, A. Yu. Palyanov

“…In addition, in principle, the rules by which the brain changes during the life of the organism can also evolve. …”
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Genomic Introgression Between Critically Endangered and Stable Species of Darwin's Tree Finches on the Galapagos Islands by Rachael Y. Dudaniec, Sonu Yadav, Julian Catchen, Sonia Kleindorfer

“…Alleles were annotated to genes associated with inflammation, immunity, brain function and development. We provide evidence that introgression among a critically endangered and stable species of Darwin's tree finch across years may aid in the retention of adaptive alleles and genetic diversity in birds threatened with extinction.…”
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Cardiac Effects of Thyrotropin Oversuppression with Levothyroxine in Young Women with Differentiated Thyroid Cancer by Kyung-Soon Hong, Jung-Woo Son, Ohk Hyun Ryu, Moon-Gi Choi, Ji Yeon Hong, Seong Jin Lee

“…Controls matched for age, sex, and body mass index (BMI) were compared in terms of the levels of serum free T4, free T3, TSH, plasma N-terminal pro-brain natriuretic peptide (NT-pro-BNP), and cardiac functions and structures. …”
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Cholinergic Potentiation of Restoration of Visual Function after Optic Nerve Damage in Rats by Mira Chamoun, Elena G. Sergeeva, Petra Henrich-Noack, Shaobo Jia, Lisa Grigartzik, Jing Ma, Qing You, Frédéric Huppé-Gourgues, Bernhard A. Sabel, Elvire Vaucher

“…Enhancing cortical plasticity and brain connectivity may improve residual vision following a visual impairment. …”
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Dendritic excitations govern back-propagation via a spike-rate accelerometer by Pojeong Park, J. David Wong-Campos, Daniel G. Itkis, Byung Hun Lee, Yitong Qi, Hunter C. Davis, Benjamin Antin, Amol Pasarkar, Jonathan B. Grimm, Sarah E. Plutkis, Katie L. Holland, Liam Paninski, Luke D. Lavis, Adam E. Cohen

“…We mapped sub-millisecond voltage dynamics throughout the dendritic trees of CA1 pyramidal neurons under diverse optogenetic and synaptic stimulus patterns, in acute brain slices. Our data show history-dependent spike back-propagation in distal dendrites, driven by locally generated Na+ spikes (dSpikes). …”
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Primary Nocardia Infection Causing a Fluorodeoxyglucose-Avid Right Renal Mass in a Redo Lung Transplant Recipient by Sreeja Biswas Roy, Mitchell D. Ross, Pradnya D. Patil, Richard Trepeta, Ross M. Bremner, Tanmay S. Panchabhai

“…Computed tomography of the chest and brain revealed no lesions consistent with infection. …”
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Changes in Hippocampal Plasticity in Depression and Therapeutic Approaches Influencing These Changes by Wenbo Xu, Xiaoxiao Yao, Fangyi Zhao, Haisheng Zhao, Ziqian Cheng, Wei Yang, Ranji Cui, Songbai Xu, Bingjin Li

“…However, no hypothesis can fully explain the pathogenesis of depression. At present, the brain-derived neurotrophic factor (BDNF) and neurogenesis hypotheses have highlighted the important role of plasticity in depression. …”
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A fulminant case of JC virus encephalopathy supporting a novel syndrome associated with JC virus infection of cortical neurons by Matteo Ciocca, Marta Pirovano, Monica Lodi, Antonino Romeo, Vincenza Fetoni

“…He passed away 3 weeks after onset of symptoms. On admission, brain MRI demonstrated a prominent grey matter involvement. …”
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Exosomes in neuron-glia communication: A review on neurodegeneration by Naeimeh Akbari-Gharalari, Sina Khodakarimi, Farshad Nezhadshahmohammad, Mohammad Karimipour, Abbas Ebrahimi-Kalan, Jiagian Wu

“…Notably, the ability of exosomes to traverse the blood-brain barrier (BBB) has significant implications. …”
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The Human Microglia Atlas (HuMicA) unravels changes in disease-associated microglia subsets across neurodegenerative conditions by Ricardo Martins-Ferreira, Josep Calafell-Segura, Bárbara Leal, Javier Rodríguez-Ubreva, Elena Martínez-Saez, Elisabetta Mereu, Paulo Pinho E Costa, Ariadna Laguna, Esteban Ballestar

“…We constructed an atlas of human brain immune cells by integrating nineteen single-nucleus RNA-seq and single-cell RNA-seq datasets from multiple neurodegenerative conditions, comprising 241 samples from patients with Alzheimer’s disease, autism spectrum disorder, epilepsy, multiple sclerosis, Lewy body diseases, COVID-19, and healthy controls. …”
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A Comprehensive Review on the Beneficial Roles of Vitamin D in Skin Health as a Bio-Functional Ingredient in Nutricosmetic, Cosmeceutical, and Cosmetic Applications by Sofia Neonilli A. Papadopoulou, Elena A. Anastasiou, Theodora Adamantidi, Anna Ofrydopoulou, Sophia Letsiou, Alexandros Tsoupras

“…Nevertheless, recent research has shown its importance for the brain, heart, muscles, immune system, and skin health, due to its distinct bio-functionality in almost every tissue in the human body. …”
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