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4581
Circadian rhythm related genes signature in glioma for drug resistance prediction: a comprehensive analysis integrating transcriptomics and machine learning
Published 2025-02-01“…Abstract Background Gliomas, 24% of all primary brain tumors, have diverse histology and poor survival rates, with about 70% recurring due to acquired or de novo resistance. …”
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4582
Nootkatone inhibits the progression of glioblastoma by activating the ATF4-CHOP-CHAC1 pathway
Published 2025-01-01“…Abstract Glioblastoma multiforme (GBM) represents a primary brain tumor that is widely prevalent, and clinical drugs available for its treatment exhibit varying degrees of resistance. …”
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4583
Comparing Fluconazole and Nystatin as Antifungal Prophylactics in Very Low Birth Weight Infants: A Randomized Clinical Trial
Published 2024-07-01“…Intraventricular hemorrhage was detected in brain ultrasound examination in three (5.0%) neonates in group B and seven (11.7%) in group A (p =0.020). …”
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4584
Exploring the influence of pregnancy on cognitive function in women: a systematic review
Published 2025-01-01“…Objective This study aims to systematically review existing literature and empirical research to better understand the phenomenon known as “pregnancy brain” and its association with cognitive change. …”
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4585
Clinical Outcomes and Quality of Life in Recipients of Livers Donated after Cardiac Death
Published 2015-01-01“…We compared clinical outcomes of DCD recipients (n=60) to those of donation after brain death (DBD) liver recipients (n=669) during the same time period. …”
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4586
Allogeneic Adipose-Derived Mesenchymal Stromal Cells Ameliorate Experimental Autoimmune Encephalomyelitis by Regulating Self-Reactive T Cell Responses and Dendritic Cell Function
Published 2017-01-01“…The aim of the current study has been to further characterize the immunomodulatory mechanisms of adipose tissue-derived MSCs (ASCs) in vitro and in vivo using the EAE model of chronic brain inflammation in mice. We found that murine ASCs (mASCs) suppress T cell proliferation in vitro via inducible nitric oxide synthase (iNOS) and cyclooxygenase- (COX-) 1/2 activities. mASCs also prevented the lipopolysaccharide- (LPS-) induced maturation of dendritic cells (DCs) in vitro. …”
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4587
Efficacy of the Enteroadsorbent Silicol®gel in Adults with Irritable Bowel Syndrome Subtypes IBS-D or Mixed: Observational Open-Label Study
Published 2023-01-01“…Irritable bowel syndrome (IBS) is a common chronic gut-brain interaction disorder with limited effective treatment options. …”
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4588
Omega-3 Polyunsaturated Fatty Acids Enhance Neuronal Differentiation in Cultured Rat Neural Stem Cells
Published 2013-01-01“…Polyunsaturated fatty acids (PUFAs) can induce neurogenesis and recovery from brain diseases. However, the exact mechanisms of the beneficial effects of PUFAs have not been conclusively described. …”
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4589
Quantifying Podocyte Number in a Small Sample Size of Glomeruli with CUBIC to Evaluate Podocyte Depletion of db/db Mice
Published 2023-01-01“…In this study, clear, unobstructed brain imaging cocktails and computational analysis (CUBIC), one of three-dimensional optical clearing approaches, was used which combines tissue clearing, immunolabeling, and a light-sheet microscope to image and evaluate podocytes in C57BL/6 (C57) and db/db mice. …”
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4590
A case report of fatal familial insomnia with cerebrospinal fluid leukocytosis during the COVID-19 epidemic and review of the literature
Published 2024-12-01“…A lumbar puncture was performed again, and it was found that the total Tau protein in the cerebrospinal fluid was elevated, and PET results showed that brain metabolism decreased. Finally, a genetic test was used to confirm the diagnosis of FFI. …”
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4591
Artificial Taste: Advances and Innovative Applications in Healthcare
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4592
A randomized controlled study of auricular point acupressure to manage chemotherapy-induced neuropathy: Study protocol.
Published 2024-01-01“…Secondary outcomes include evaluating pain sensory thresholds, motor and cognitive functioning, inflammatory signaling, brain connectivity, opioid use, and quality of life. …”
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4593
Oxytocin: co-evolution of human and domesticated animals
Published 2016-05-01“…At the behavioral level, OT facilitates intraspecific social contacts in mammals via various mechanisms ranging from the suppression of neuroendocrine stress responses to the direct OT action on neurons of socially relevant brain regions. Recent reports indicated possible contribution of OT to the formation of the social bond between domesticated mammals (dog, sheep, cattle) and humans. …”
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4594
Why heads matter in palaeoanthropology: The impacts and consequences of collecting skulls
Published 2025-02-01“…Finally, we focus on how this early overemphasis on skulls, and especially brain size/intelligence, may have skewed our understanding of human evolution and contributed to ideas of human exceptionalism. …”
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4595
GENOME POLITICS: STRATEGY AND TACTICS
Published 1999-01-01“…Human mental and consciousness activity, brain functions obtained by learning mask the dependence of these activities on the genome. …”
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4596
Bilateral Transplantation of Allogenic Adult Human Bone Marrow-Derived Mesenchymal Stem Cells into the Subventricular Zone of Parkinson’s Disease: A Pilot Clinical Study
Published 2012-01-01“…This study demonstrates the safety of adult allogenic human BM-MSCs transplanted into the SVZ of the brain and its efficacy in early-stage PD patients.…”
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4597
Developing a taxonomy to describe offspring outcomes in studies involving pregnant mammals' exposure to non-tobacco nicotine: A systematic scoping review.
Published 2023-01-01“…The most frequently used outcomes were those detecting changes in the brain (n = 265), physical parameters measured in whole animals (n = 122) and any respiratory system changes (n = 97).…”
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4598
Response to the SAMHSA Clinical Advisory: Considerations for Genetic Testing in the Assessment of Substance Use Disorder Risk
Published 2025-01-01“…Louis, Missouri, USA; 8Department of Biological Sciences, Dornsife College of Letters, Arts & Sciences, University of Southern California, Los Angeles, CA, USA; 9Behavioral Neuropharmacology and Neuroimaging Laboratory, Department of Pharmacology and Toxicology, Jacobs School of Medicine and Biomedical Sciences, Clinical Research Institute on Addictions, University at Buffalo, Buffalo, NY, USA; 10Department of Family Medicine, Jefferson Health Northeast, Philadelphia, PA, USA; 11Department of Psychiatry, Stanford University School of Medicine, Palo Alto, CA, USA; 12Department of Psychiatry, Harvard University School of Medicine, Cambridge, MA, USA; 13Cellular and Molecular Research Center, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran; 14Brain & Behavior Laboratory, Department of Psychology, Curry College, Milton, Massachusetts, USA; 15Department of Psychiatry, Texas Tech University Health Sciences, School of Medicine, Midland, TX, USACorrespondence: Rajendra D Badgaiyan; Kenneth Blum, Email badgaiyan@gmail.com; drd2gene@gmail.com…”
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4599
The use of dance to improve the health and wellbeing of older adults: A global scoping review of research trials.
Published 2024-01-01“…Less than 40% of health assessments showed positive change, with more consistent benefits to physical endurance, strength, and function, moderate impacts on psychosocial health, and limited benefits to cognitive and brain health, and falls and falls risk.<h4>Conclusion</h4>Dance is a meaningful, safe, adaptable, and low-cost health resource for older adults. …”
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4600
High resolution multi-delay arterial spin labeling with self-supervised deep learning denoising for pediatric choroid plexus perfusion MRI
Published 2025-03-01“…Choroid plexus (CP) is an important brain structure that produces cerebrospinal fluid (CSF). …”
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