A Case of Neuromyelitis Optica: Puerto Rican Woman with an Increased Time Lag to Diagnosis and a High Response to Eculizumab Therapy by Ramón Vega, Benjamín González, Kiara Ortiz, Viviana Martínez, David Carmona, Ivonne Vicente, Javier Chapa, Ángel Chinea

“…The patient had cervical and brain magnetic resonance imaging (MRI) conducted in June 2020, which depicted a remarkable decrease in swelling and hyperintensity within the cervical spinal cord with no enhancing lesions when compared with the first MRI from February 2019. …”
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Partial Volume Reduction by Interpolation with Reverse Diffusion

“…On gray level, scanned text, MRI physical phantom, and brain images, restored images processed with the new method were visually much closer to high-resolution counterparts than those obtained with common interpolation methods.…”
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IL-17 and IL-22 in Cerebrospinal Fluid and Plasma Are Elevated in Guillain-Barré Syndrome by Shujuan Li, Ming Yu, Haifeng Li, Hongliang Zhang, Yanfang Jiang

“…The increased levels of IL-17 and IL-22 in CSF may be explained by the disruption of blood-brain barrier (BBB) and peripheral nervous system (PNS) local inflammation in GBS. …”
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Effect of cerebrolysin on dopaminergic neurodegeneration of rat with oxidative stress induced by 3-nitropropionic acid by Calderón Guzmán David, Brizuela Norma Osnaya, Ortíz Herrera Maribel, Hernández García Ernestina, Barragán Mejía Gerardo, Juárez Olguín Hugo, Valenzuela Peraza Armando, Attilus Jonas, Labra Ruíz Norma

“…The study tested the hypothesis that cerebrolysin protects the brain from free radicals in rats treated with 3-nitropropionic acid (3-NPA). …”
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Neural network for step anomaly detection in head motion during fMRI using meta-learning adaptation by N.S. Davydov, V.V. Evdokimova, P.G. Serafimovich, V.I. Protsenko, A.G. Khramov, A.V. Nikonorov

“…Quality assessment and artifact detection in functional magnetic resonance imaging (fMRI) data is essential for clinical applications and brain research. Subject head motion remains the main source of artifacts - even the tiniest head movement can perturb the structural and functional data derived from the fMRI. …”
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High order expression dependencies finely resolve cryptic states and subtypes in single cell data by Abel Jansma, Yuelin Yao, Jareth Wolfe, Luigi Del Debbio, Sjoerd V Beentjes, Chris P Ponting, Ava Khamseh

“…Stator’s finer resolution is clear from analyses of mouse embryonic brain, and human healthy or diseased liver. Rather than only coarse-scale labels of cell type, Stator further resolves cell types into subtypes, and these subtypes into stages of maturity and/or cell cycle phases, and yet further into portions of these phases. …”
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Germinoma with Involvement of Midline and Off-Midline Intracranial Structures by Monica Graciela Loto, Karina Danilowicz, Santiago González Abbati, Rafael Torino, Alejandro Misiunas

“…A case of an 18-year-old male patient with progressive right-sided hemiparesis and panhypopituitarism was reviewed. Brain MRI showed a solid mass involving pituitary and hypothalamus with thickening of pituitary stalk, high intensity lesions on T2-weighted imaging in left internal capsule, caudate nucleus, globus pallidus, and mild atrophy of the left internal capsule and cerebral peduncle. …”
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Large language models for causal hypothesis generation in science by Kai-Hendrik Cohrs, Emiliano Diaz, Vasileios Sitokonstantinou, Gherardo Varando, Gustau Camps-Valls

“…Towards the goal of understanding the causal structure underlying complex systems—such as the Earth, the climate, or the brain—integrating Large language models (LLMs) with data-driven and domain-expertise-driven approaches has the potential to become a game-changer, especially in data and expertise-limited scenarios. …”
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Mechanisms of Cancer-Induced Bone Pain by Wang X, Li L, Wang Y

“…The central mechanisms usually involve biochemical and electrophysiological changes in the spinal cord and brain. The spinal cord is the main processing center for nociceptive signals. …”
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Maximizing information in neuron populations for neuromorphic spike encoding by Ahmad El Ferdaoussi, Eric Plourde, Jean Rouat

“…One of the ways neuromorphic applications emulate the processing performed by the brain is by using spikes as inputs instead of time-varying analog stimuli. …”
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Protective Role of rAAV-NDI1, Serotype 5, in an Acute MPTP Mouse Parkinson's Model by Jennifer Barber-Singh, Byoung Boo Seo, Akemi Matsuno-Yagi, Takao Yagi

“…It is conceivable that the AAV-serotype5 carrying the NDI1 gene is a powerful tool for proof-of-concept study to demonstrate complex I defects as the causable factor in diseases of the brain.…”
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Clinical Evaluation of Patients with Spinal Cord Infarction in Mashhad, Iran by Kavian Ghandehari, Mohammad Reza Gerami Sarabi, Parham Maarufi

“…An equal number of patients with Brain Infarction (BI) were randomly selected from our stroke registry data bank. …”
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Nonpharmacological Modulation of Chronic Inflammation in Parkinson’s Disease: Role of Diet Interventions by Stefania Kalampokini, Anouck Becker, Klaus Fassbender, Epameinondas Lyros, Marcus M. Unger

“…Recent evidence suggests that neuroinflammation in PD might originate in the intestine and the bidirectional communication between the central and enteric nervous system, the so-called “gut-brain axis,” has received growing attention due to its contribution to the pathogenesis of neurological disorders. …”
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Effect of the application of humanized nursing care on the clinical outcomes of neonates with hyperbilirubinemia by Sahar Mahmoud Elkhedr Abdelgawad, Eman Salah Elmetwaly Abdelrahman Galalah, Heba Saied El-mahdy, Nagafa Hafez Farag Elmahdy

“…Abstract Background Neonatal hyperbilirubinemia is a potentially fatal condition that has toxic effects on the brain and may have negative effects. Humanized care is a comprehensive approach that focuses on the nutritional, therapeutic and hygienic needs of neonates, which helps in the resolution of hyperbilirubinemia. …”
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The Emerging Roles of the Calcineurin-Nuclear Factor of Activated T-Lymphocytes Pathway in Nervous System Functions and Diseases by Maulilio John Kipanyula, Wahabu Hamisi Kimaro, Paul F. Seke Etet

“…Additionally increased activities of endogenous regulators of calcineurin like plasma membrane Ca2+-ATPase (PMCA) and regulator of calcineurin 1 (RCAN1) also cause neuronal and glial loss and related functional alterations, in neurodegenerative diseases, psychotic disorders, epilepsy, and traumatic brain and spinal cord injuries. Treatment with calcineurin/NFAT inhibitors induces some degree of neuroprotection and decreased reactive gliosis in the central and peripheral nervous system. …”
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Beyond sensitivity: what are the enabling opportunities of OPM-MEG? by Timothy P. L. Roberts, Timothy P. L. Roberts, Charlotte Birnbaum, Luke Bloy, William Gaetz, William Gaetz

“…Application to the developing infant brain will be considered as well as application to pediatric neuropsychiatric and developmental disorders, such as autism spectrum disorder. …”
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EEG-Triggered Functional Electrical Stimulation Therapy for Restoring Upper Limb Function in Chronic Stroke with Severe Hemiplegia by Cesar Marquez-Chin, Aaron Marquis, Milos R. Popovic

“…We report the therapeutic effects of integrating brain-computer interfacing technology and functional electrical stimulation therapy to restore upper limb reaching movements in a 64-year-old man with severe left hemiplegia following a hemorrhagic stroke he sustained six years prior to this study. …”
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Landscape of Alternative Splicing Events Related to Prognosis and Immune Infiltration in Glioma: A Data Analysis and Basic Verification by Hong-xin Su, Gang Yang, Fei Su, Chen-xiao Hu, Tao Zhang, Jun-tao Ran, Quan-lin Guan

“…Glioma is a prevalent primary brain cancer with high invasiveness and typical local diffuse infiltration. …”
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The Microtubule-Associated Protein Tau and Its Relevance for Pancreatic Beta Cells by Magdalena Maj, Gregor Hoermann, Sazan Rasul, Wolfgang Base, Ludwig Wagner, Johannes Attems

“…We have previously shown that MAPT is present in human islets of Langerhans, human insulinomas, and pancreatic beta-cell line models, with biophysical similarities to the pathological MAPT in the brain. Here, we further studied MAPT in pancreatic endocrine tissue to better understand the mechanisms that lead to functional dysregulation of pancreatic beta cells. …”
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Olfactory transport efficiency of the manganese oxide nanoparticles (II) after their single or multiple intranasal administrations by A. V. Romashchenko, M. B. Sharapova, D. V. Petrovskii, M. P. Moshkin

“…Thus, repeated intranasal introduction of MnO-NPs reduces the efficiency of nanoparticle olfactory transport from the nasal cavity to the brain, which is combined with the increase in the viscosity of the mucosal layer and the reduction in the number of synaptic contacts between OB and OE. …”
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