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3961
Strategies to innovate emergency care of status epilepticus
Published 2025-01-01Get full text
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3962
Aducanumab, a Novel Anti-Amyloid Monoclonal Antibody, for the Treatment of Alzheimer’s Disease: A Comprehensive Review
Published 2022-01-01“…Despite this skepticism, aducanumab has proven to significantly decrease amyloid in all cortical brain regions examined. In summary, aducanumab has provided hope for those working toward the goal of providing patients a safe and viable treatment option in the management of AD.…”
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3963
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3964
Combining Convolutional Neural Network (CNN) and Grad-CAM for Parkinson’s Disease Prediction and Visual Explanation
Published 2024-09-01“…Parkinson's disease is one of the types of neurological diseases that is caused by the destruction of brain cells that produce dopamine. Early detection of Parkinson's disease is an important factor in slowing the progression of the disease. …”
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3965
Regeneration of Zebrafish CNS: Adult Neurogenesis
Published 2016-01-01“…Zebrafish is an excellent animal model, which can repair several organs like damaged retina, severed spinal cord, injured brain and heart, and amputated fins. The focus of the present paper is on spinal cord regeneration in adult zebrafish. …”
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3966
A Case of Classic Raymond Syndrome
Published 2012-01-01“…Neurological examination showed he had right abducens nerve palsy, left-sided paresis of the lower part of the face and limbs, and left hyperreflexia. A brain MRI showed a subacute infarct in the right mid-pons. …”
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3967
Perception and treatment of melancholy in the writings of Hildegard of Bingen (c. 1098-1179)
Published 2021-12-01“…Melancholy was interpreted in Hildegard’s medical texts as a heart and a brain disease which was caused by the overabundance of black bile produced in the spleen. …”
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3968
Two-Cloud-Servers-Assisted Secure Outsourcing Multiparty Computation
Published 2014-01-01Get full text
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3969
A septo-hypothalamic-medullary circuit directs stress-induced analgesia
Published 2025-01-01“…However, where and how acute stress and pain pathways interface in the brain are poorly understood. Here, we describe how the dorsal lateral septum (dLS), a forebrain limbic nucleus, facilitates SIA through its downstream targets in the lateral hypothalamic area (LHA) of mice. …”
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3970
Perbedan Terapi Madu dan Multi Vitamin Terhadap Kadar Hemoglobin, Albumin dan Status Nutrisi Pada Anak Balita
Published 2011-12-01“…Optimal body growth also includes brain development, which determines someone's intelligence. …”
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3971
Dysregulation of the Autophagy-Endolysosomal System in Amyotrophic Lateral Sclerosis and Related Motor Neuron Diseases
Published 2012-01-01“…Amyotrophic lateral sclerosis (ALS) is a heterogeneous group of incurable motor neuron diseases (MNDs) characterized by a selective loss of upper and lower motor neurons in the brain and spinal cord. Most cases of ALS are sporadic, while approximately 5–10% cases are familial. …”
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3972
Deep learning to decode sites of RNA translation in normal and cancerous tissues
Published 2025-02-01“…We demonstrate that RiboTIE successfully recapitulates known findings and provides novel insights into the regulation of RNA translation in both normal brain and medulloblastoma cancer samples. Our results suggest that RiboTIE is a versatile tool that can significantly improve the accuracy and depth of Ribo-Seq data analysis, thereby advancing our understanding of protein synthesis and its implications in disease.…”
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3973
Viral Vector Induction of CREB Expression in the Periaqueductal Gray Induces a Predator Stress-Like Pattern of Changes in pCREB Expression, Neuroplasticity, and Anxiety in Rodents
Published 2009-01-01“…The findings of this study suggest that by increasing CREB and pCREB in the right lateral PAG, it is possible to produce rats that exhibit behavioral, brain, and molecular changes that closely resemble those seen in predator stressed rats.…”
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3974
A study to determine the effect of nano-selenium and thymoquinone on the Nrf2 gene expression in Alzheimer’s disease
Published 2025-12-01“…The levels of Nrf2 in brain tissues were evaluated using real-time PCR.Results Nrf2 mean expression levels in the nano-selenium-treated rats, the thymoquinone-treated rats, and the rats that were given both treatments all increased significantly compared to AD rats with no treatment.Conclusions This study showed that nano-selenium and thymoquinone elevated Nrf2 gene expression levels in AD.…”
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3975
Stress-Induced Changes in the Gastrointestinal Motor System
Published 1999-01-01“…In animals, the most consistent findings include retardation of gastric emptying in response to various stressors; acceleration of gastric emptying upon cold stress, presumably through the secretion of brain thyroglobulin-hormone; acceleration of intestinal transit; and stimulation of colonic transit and fecal output. …”
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3976
An Intracranial Extradural Dermoid Cyst Presenting with Two Dermal Sinuses and an Abscess in a Child
Published 2021-01-01“…Herein, we report a rare case of a 1-year-old female presenting with a midline, scalp abscess. Brain MRI revealed an intracranial, extradural tumor, with features suggestive of a dermoid cyst, unusually located in the crista galli, and complicated by the formation of two cutaneous sinus tracts. …”
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3977
Neurogranin in Alzheimer's Disease: Roles in synaptic function, pathology, and potential as a diagnostic biomarker
Published 2024-09-01“…This review, therefore, looked at the functionality of Ng in the brain, its association with other synaptic proteins, and its applicability as a diagnostic marker in AD. …”
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3978
Early growth response 1 transcription factor and its context-dependent functions in glioblastoma
Published 2024-08-01“…Glioblastoma is the most aggressive form of primary brain tumour in adults. This tumour employs numerous transcription factors to advance and sustain its progression. …”
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3979
Blood Plasma of Patients with Parkinson’s Disease Increases Alpha-Synuclein Aggregation and Neurotoxicity
Published 2016-01-01“…A pathological hallmark of Parkinson’s disease (PD) is formation of Lewy bodies in neurons of the brain. This has been attributed to the spread of α-synuclein (α-syn) aggregates, which involves release of α-syn from a neuron and its reuptake by a neighboring neuron. …”
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3980
Comprehensive Insight of Neurodegenerative Diseases and The Role of Neurotoxin Agents — Glutamate
Published 2020-04-01“…GSH plays an important role in the disposal of peroxides by brain cells and in the protection against ROS. Depletion of GSH renders the cell to oxidative stress and ultimately leading to cell death. …”
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