Botulinum Neurotoxin Application to the Severed Femoral Nerve Modulates Spinal Synaptic Responses to Axotomy and Enhances Motor Recovery in Rats by Marcel Irintchev, Orlando Guntinas-Lichius, Andrey Irintchev

“…Botulinum neurotoxin A (BoNT) and brain-derived neurotrophic factor (BDNF) are known for their ability to influence synaptic inputs to neurons. …”
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Streptococcus intermedius Causing Necrotizing Pneumonia in an Immune Competent Female: A Case Report and Literature Review by Faris Hannoodi, Israa Ali, Hussam Sabbagh, Sarwan Kumar

“…Radiological findings varied from an isolated pleural effusion to systemic disease with the presence of brain abscesses. Immunocompetence appears to correlate well with the overall prognosis. …”
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Alcohol and Suicide: Neurobiological and Clinical Aspects by Leo Sher

“…Dopaminergic dysfunction may play an important role in the pathophysiology of suicidal behavior in alcoholism. Brain damage and neurobehavioral deficits are associated with alcohol use disorders and may contribute to suicidal behavior in persons with alcohol dependence or abuse. …”
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Magnesium Homeostasis and Implications for Human Health: A Review of the Literature by Piotr Marcin Dudziak, Maria Golińska, Mateusz Łyko, Jakub Kurasz, Paweł Siudziński, Wojciech Maj, Alicja Skoczylas, Wiktoria Podlasiewicz, Katarzyna Pala, Anna Nowak

“…This review delves into the role of magnesium in human health and disease, highlighting its importance in key organs like the brain, heart, and muscles. Magnesium supplementation has shown promise in treating conditions such as migraine, depression, heart disease, and asthma. …”
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Changes of well-being over the pandemic: a survey across generational cohorts by Chen Wang, Yizi Nie, Xiaoyu Lan, Qianqian Huang, Qunsen Dai, Chao Zhou

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Human capital investments and income inequality in Nigeria: Does institutional quality matter? by Adeyemi Michael Anagun, Peter Olugbenga Oluwo, Peter Minasu Agosu

“…Based on the findings revealed, the study recommends that the government should by all means and economic resources increase the budget of human capital to enhance the reduction of income inequality in the country and place more emphasis on providing education grants and incentives that encourage the reduction of brain drain.  …”
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Comments on “Comparing the productive vocabularies of Grey parrots (Psittacus erithacus) and young children” by Irene M. Pepperberg

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Dysregulation of REST and its target genes impacts the fate of neural progenitor cells in down syndrome by Tan Huang, Sharida Fakurazi, Pike-See Cheah, King-Hwa Ling

“…Downregulation of REST may lead to defects in post-differentiation neuronal morphology in the brain of the DS fetal. This study aims to elucidate the role of REST in DS-derived NPCs using bioinformatics analyses and laboratory validations. …”
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Synaptic plasticity in fronto-insular circuits underlying stress susceptibility and resilience by Devin Rocks, Conor Liston

“…In this review, we examine how chronic stress and antidepressants modulate synaptic connectivity in stress-sensitive brain circuits. We discuss the roles of various synaptic and molecular pathways in these processes, their interaction with circadian rhythms, and their contributions to the regulation of mood, with a particular focus on anhedonia. …”
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A case of attempted bilateral self-enucleation in a patient with bipolar disorder by Hannah Muniz Castro, John Alvarez, Robert G. Bota, Marc Yonkers, Jeremiah Tao

“…Other less commonly associated disorders include obsessive-compulsive disorder, depression, mental retardation, neurosyphilis, Lesch-Nyhan syndrome, and structural brain lesions.…”
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Atlantoaxial fixation for treatment of syringobulbia and syringomyelia: Case report and literature review by Kaunda Emeka Ibebuike, Oluwamayowa Opara

“…Neuroradiological studies of the brain and the whole spine revealed an extensive syringomyelia extending from the medulla oblongata to the T12 thoracic spinal level. …”
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Tissue Anisotropy Modeling Using Soft Composite Materials by Arnab Chanda, Christian Callaway

“…The mechanical behavior of the soft composites was characterized using hyperelastic material models such as Mooney-Rivlin’s, Humphrey’s, and Veronda-Westmann’s model and also compared with the anisotropic mechanical behavior of the human skin, pelvic tissues, and brain tissues. This work lays the foundation for the experimental modelling of tissue anisotropy, which combined with microscopic studies on tissues can lead to refinements in the simulation of localized fiber distribution and orientations, and enable the development of biofidelic anisotropic tissue phantom materials for various tissue engineering and testing applications.…”
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Fatal Overdose due to Confusion of an Transdermal Fentanyl Delivery System by Ingo Voigt

“…CCT scan presented a global hypoxic brain disease. Treatment and Outcome. The patient was discharged 30 days after admittance in a hemodynamic stable condition but a vegetative state and transferred to a rehabilitation center. …”
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Phospho-seq: integrated, multi-modal profiling of intracellular protein dynamics in single cells by John D. Blair, Austin Hartman, Fides Zenk, Philipp Wahle, Giovanna Brancati, Carol Dalgarno, Barbara Treutlein, Rahul Satija

“…We apply our workflow to cell lines, induced pluripotent stem cells, and months-old retinal and brain organoids to demonstrate its broad applicability. …”
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Cox-2 Plays a Vital Role in the Impaired Anxiety Like Behavior in Colchicine Induced Rat Model of Alzheimer Disease by Susmita Sil, Tusharkanti Ghosh

“…The present study showed that anxiolytic behavior in cADr is predominantly due to cox-2 mediated neuroinflammation induced neurodegeneration in the brain.…”
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Electromagnetic Fields, Oxidative Stress, and Neurodegeneration by Claudia Consales, Caterina Merla, Carmela Marino, Barbara Benassi

“…Since free radicals are essential for brain physiological processes and pathological degeneration, research focusing on the possible influence of the EMFs-driven oxidative stress is still in progress, especially in the light of recent studies suggesting that EMFs may contribute to the etiology of neurodegenerative disorders. …”
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Aduhelm, a novel anti-amyloid monoclonal antibody, for the treatment of Alzheimer’s Disease: A comprehensive review by Hannah W. Haddad, Garett W. Malone, Nicholas J. Comardelle, Arielle E. Degueure, Salomon Poliwoda, Rachel J. Kaye, Kevin S. Murnane, Adam M Kaye, Alan D. Kaye

“…Despite skepticism, Adulhelm has proven to significantly decrease amyloid in all cortical brain regions examined. With such high stakes and potential, further research into Adulhelm's clinical efficacy is warranted in the treatment of AD.…”
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Current Trends in Targeted Therapies for Glioblastoma Multiforme by Fumiharu Ohka, Atsushi Natsume, Toshihiko Wakabayashi

“…To date, many studies report several determinants of resistance to this aggressive therapy: (1) O6-methylguanine-DNA methyltransferase (MGMT), (2) the complexity of several altered signaling pathways in GBM, (3) the existence of glioma stem-like cells (GSCs), and (4) the blood-brain barrier. Many studies aim to overcome these determinants of resistance to conventional therapy by using various approaches to improve the dismal prognosis of GBM such as modifying TMZ administration and combining TMZ with other agents, developing novel molecular-targeting agents, and novel strategies targeting GSCs. …”
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Germinoma in the Internal Auditory Canal Mimicking a Vestibular Schwannoma by Rubén Martín-Hernández, Diego Hernando Macías-Rodríguez, Ángel Muñoz-Herrera, Juan Carlos Del Pozo-de Dios, Santiago Santa Cruz-Ruiz, Ángel Batuecas-Caletrío

“…The appearance of a primary germinoma in the central nervous system but not on or near the midline or within the brain is exceptional. It may occur at any age; however, it is rare in patients over 50 years old. …”
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How Accurately Can Prostate Gland Imaging Measure the Prostate Gland Volume? Results of a Systematic Review by David R. H. Christie, Christopher F. Sharpley

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