Xiaoyao Pills Attenuate Inflammation and Nerve Injury Induced by Lipopolysaccharide in Hippocampal Neurons In Vitro by Yang Fang, Boyu Shi, Xiaobo Liu, Jie Luo, Zhili Rao, Rong Liu, Nan Zeng

“…The expression levels of IL-6, TNF-α, IDO, 5-HT, brain-derived neurotrophic factor, and β-nerve growth factor were detected by enzyme-linked immunosorbent assay. mRNA levels of IL-6, TNF-α, 5-HT1A, IDO-1, brain-derived neurotrophic factor, nerve growth factor, tropomyosin receptor kinase B, tropomyosin receptor kinase A, and cAMP response element-binding protein were detected by reverse transcription-polymerase chain reaction. …”
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Exploration of whether socioeconomic factors affect the results of priority setting partnerships: updating the top 10 research priorities for the management of Parkinson’s in an in... by Michael Lawton, Inga Liepelt-Scarfone, Rejko Krüger, Michele T Hu, Christine Lo, Charlotte Woodward, Francesca Bowring, Jessica Welch, Patricia Sulzer, Anne-Marie Hanff

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Neuroplasticity and functional reorganization of language in patients with arteriovenous malformations: insights from neuroimaging and clinical interventions by Jialong Yuan, Hongchuan Niu, Chengxu Lei, Ruichen Xu, Yutong Liu, Kexin Yuan, Linru Zou, Shihao He, Shihao He, Yuanli Zhao, Yuanli Zhao

“…Patients with arteriovenous malformations (AVMs) located in the functional area of speech often exhibit language dysfunction, and neuroplasticity allows the brain of some patients to regain speech through functional reorganization. …”
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Neurodiversity: post-cognitivist foundations of the 3E approach for educational inclusion of autistic students with technology by Ronnie Videla, Ronnie Videla, May Britt Aros, Francisco Parada, Leonie Kausel, Eduardo Sandoval-Obando, Daniela Jorquera, Daniela Jorquera, David Ibacache, Sebastián Maluenda, Pablo Rodríguez-Herrero, Carola Cerpa, María Jesús González, Marcelo Chávez, Paola Ramírez

“…The concept of neurodiversity has gained strength in the last years to highlight the value of individual differences based on relevant variations in brain functioning. Inclusive education has embraced neurodiversity to promote a culture centered on valuing diversity, in response to clinical models based on deficits or disorders. …”
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Dynamic Variation in Hippocampal Metabolism after Acute Stress Exposure: An In Vivo Proton Magnetic Resonance Spectroscopy Study at 9.4 T by Yoon Ho Hwang, Min-Hee Lee, Chang-Soo Yun, Yong-Tae Kim, Hyeon-Man Baek, Bong Soo Han, Dong Youn Kim

“…They have analyzed the metabolic alterations in the brain at a particular time after acute stress. This study explored the temporal variations of the brain metabolites in the hippocampus after acute restraint stress using proton magnetic resonance spectroscopy. …”
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Atypical early neural responses to native and non-native language in infants at high likelihood for developing autism by Lauren Wagner, Megan Banchik, Tawny Tsang, Nana J. Okada, Rebecca Altshuler, Nicole McDonald, Susan Y. Bookheimer, Shafali S. Jeste, Shulamite Green, Mirella Dapretto

“…Infants were presented with native (English) and novel (Japanese) speech while sleeping naturally in the scanner. Whole-brain and a priori region-of-interest analyses were conducted to evaluate neural differences in language processing based on likelihood group and language condition. …”
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A novel proficiency test to assess the animal diagnostic investigation process in identifying an unknown toxicant by Andriy Tkachenko, Yang Chen, Marissa Petrey, Scott Fritz, Tim Walsh, David Rotstein, Megan R. Miller, Bruce Williams, Michael Dark, Matthew Kmet, Ravinder Reddy, Gregory Tyson, Sarah M. Nemser

“…VDLs received a case description outlining neurological signs in cattle, a digitized brain histology slide, and liver and brain tissue samples for optional chemistry analysis. …”
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Multiple-Wearable-Sensor-Based Gait Classification and Analysis in Patients with Neurological Disorders by Wei-Chun Hsu, Tommy Sugiarto, Yi-Jia Lin, Fu-Chi Yang, Zheng-Yi Lin, Chi-Tien Sun, Chun-Lung Hsu, Kuan-Nien Chou

“…The 20 subjects selected to participate in this study were separated into two groups: stroke patients (11) and patients with neurological disorders other than stroke (brain concussion, spinal injury, or brain hemorrhage) (9). …”
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Immortalized Mesenchymal Stem Cells: A Safe Cell Source for Cellular or Cell Membrane-Based Treatment of Glioma by Yuxuan Zhang, Jie Liu, Yunzhao Mo, Zetao Chen, Taoliang Chen, Yan Li, Yaofeng Zheng, Shaokang Deng, Xiangdong Xu, Huajian Chen, Haoqi He, Jiansheng Chen, Tao Jin, Xinlin Sun, Yiquan Ke, Jihui Wang

“…Next, the engineered cells were injected into the brain of female BALB/c nude mice. Finally, the cell membranes of im-MSCs were labeled with DiO or DiR to detect their ability to be taken up by glioma cells and target in situ gliomas using the IVIS system. …”
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Prevalence of anhedonia in women with deep endometriosis by Aida Mallorquí, Alessandra Fortuna, Emma Segura, Gemma Cardona, Marta Espinosa, Lara Quintas-Marquès, Meritxell Gracia, Elena Angulo-Antúnez, Francisco Carmona, María-Angeles Martínez-Zamora

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Outcomes and predictors of unplanned intensive care unit admission for pediatric trauma patients by Tyler Liang, MD, Areg Grigorian, MD, Robert Painter, MD, James Jeng, MD, Theresa Chin, MD, Laura F. Goodman, MD MPH, Yigit S. Guner, MD, Catherine Kuza, MD, Jeffry Nahmias, MD MHPE

“…Significant predictors of UIA include ureteral, esophageal and brain injury.…”
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A novel anti-epileptogenesis strategy of temporal lobe epilepsy based on nitric oxide donor by Xian-Hui Zhu, Ya-Ping Zhou, Qiao Zhang, Ming-Yi Zhu, Xiao-Wei Song, Jun Li, Jiang Chen, Yun Shi, Kang-Jian Sun, Yong-Jie Zhang, Jing Zhang, Tian Xia, Bao-Sheng Huang, Fan Meng, Qi-Gang Zhou

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Platelets tune fear memory in mice by Stefano Garofalo, Alessandro Mormino, Letizia Mazzarella, Germana Cocozza, Arianna Rinaldi, Erika Di Pietro, Maria Amalia Di Castro, Eleonora De Felice, Laura Maggi, Giuseppina Chece, Diego Andolina, Rossella Ventura, Donald Ielpo, Roberto Piacentini, Myriam Catalano, Lucia Stefanini, Cristina Limatola

“…Summary: Several lines of evidence have shown that platelet-derived factors are key molecules in brain-body communication in pathological conditions. …”
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Closing the gap in dementia research by community-based cohort studies in the Chinese populationResearch in context by Xiaowen Zhou, Zhenxu Xiao, Wanqing Wu, Yuntao Chen, Changzheng Yuan, Yue Leng, Yao Yao, Qianhua Zhao, Albert Hofman, Eric Brunner, Ding Ding

“…We identified critical research gaps and propose future directions, including enhancing sample representativeness, investigating China-specific risk factors, expanding exposure measurements to the whole life-span, collecting objective data, conducting administer-friendly domain-specific cognitive assessments, adopting pathological diagnostic criteria, standardizing biobank construction, verifying multi-modal biomarkers, examining social and genetic-environmental aspects, and monitoring post-COVID cognitive health, to approach high quality of dementia studies that can provide solid evidence to policy making and promote global brain health research.…”
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Acute effects of physical exercise on cognitive function and neurotrophins in patients with type 1 diabetes: A systematic review by Emanuele Zanardo, Giulia Quinto, Francesca Battista, Federica Duregon, Marco Vecchiato, Chiara Bergia, Kirk Erickson, Andrea Ermolao, Daniel Neunhaeuserer

“…In contrast, higher levels of neurotrophins, such as brain-derived neurotrophic factor (BDNF), may be associated with better brain health. …”
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The transcriptional response of cortical neurons to concussion reveals divergent fates after injury by Mor R. Alkaslasi, Eliza Y. H. Lloyd, Austin S. Gable, Hanna Silberberg, Hector E. Yarur, Valerie S. Tsai, Mira Sohn, Gennady Margolin, Hugo A. Tejeda, Claire E. Le Pichon

“…Abstract Traumatic brain injury (TBI) is a risk factor for neurodegeneration, however little is known about how this kind of injury alters neuron subtypes. …”
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Exploring Cortical Thickness Alteration in Parkinson Disease Patients with Freezing of Gaits by E. Li, Xiuhang Ruan, Yuting Li, Guoqin Zhang, Mengyan Li, Xinhua Wei

“…The cortical thickness (CTh), segmentation volume without ventricles (BrainSegVolNotVent) and estimated total intracranial volume (eTIV) were analysed using the FreeSurfer pipeline. …”
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Cerebral Reorganization in Subacute Stroke Survivors after Virtual Reality-Based Training: A Preliminary Study by Xiang Xiao, Qiang Lin, Wai-Leung Lo, Yu-Rong Mao, Xin-chong Shi, Ryan S. Cates, Shu-Feng Zhou, Dong-Feng Huang, Le Li

“…Functional magnetic resonance imaging (fMRI) is a promising method for quantifying brain recovery and investigating the intervention-induced changes in corticomotor excitability after stroke. …”
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Incomplete recovery in patients with minor head injury directly discharged home from the emergency department: a prospective cohort follow-up study by Bram Jacobs, Joukje van der Naalt, Jan Cornelis ter Maaten, Sophie Maria Coffeng, Laura Jane Kim

“…We also evaluated the differences between patient groups in this least severe category of brain and head injury.Design Prospective cohort follow-up study.Setting Patients admitted to the emergency department (ED) of a tertiary hospital in the Netherlands.Participants 242 patients with MHI (n=100 with head injury only and n=142 with mild traumatic brain injury (mTBI)) discharged home directly after evaluation at the ED.Outcome measures The primary outcome measure was incomplete recovery at 3 months measured by the Glasgow Outcome Scale-Extended score <8. …”
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High Blood Pressure Effects on the Blood to Cerebrospinal Fluid Barrier and Cerebrospinal Fluid Protein Composition: A Two-Dimensional Electrophoresis Study in Spontaneously Hypert... by Ibrahim González-Marrero, Leandro Castañeyra-Ruiz, Juan M. González-Toledo, Agustín Castañeyra-Ruiz, Hector de Paz-Carmona, Rafael Castro, Juan R. Hernandez-Fernaud, Agustín Castañeyra-Perdomo, Emilia M. Carmona-Calero

“…The aim of the present work is to analyze the cerebrospinal fluid proteomic profile, trying to find possible biomarkers of the effects of hypertension of the blood to CSF barrier disruption in the brain and their participation in the cholesterol and β-amyloid metabolism and inflammatory processes. …”
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