Homeostasis and metabolism of iron and other metal ions in neurodegenerative diseases by Leilei Chen, Qingqing Shen, Yingjuan Liu, Yunqi Zhang, Liping Sun, Xizhen Ma, Ning Song, Junxia Xie

“…Abstract As essential micronutrients, metal ions such as iron, manganese, copper, and zinc, are required for a wide range of physiological processes in the brain. However, an imbalance in metal ions, whether excessive or insufficient, is detrimental and can contribute to neuronal death through oxidative stress, ferroptosis, cuproptosis, cell senescence, or neuroinflammation. …”
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Loss of MEF2C function by enhancer mutation leads to neuronal mitochondria dysfunction and motor deficits in mice by Ali Yousefian-Jazi, Suhyun Kim, Jiyeon Chu, Seung-Hye Choi, Phuong Thi Thanh Nguyen, Uiyeol Park, Min-gyeong Kim, Hongik Hwang, Kyungeun Lee, Yeyun Kim, Seung Jae Hyeon, Hyewhon Rhim, Hannah L. Ryu, Grewo Lim, Thor D. Stein, Kayeong Lim, Hoon Ryu, Junghee Lee

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The Longitudinal Neurophysiological Adaptation of a Division I Female Lacrosse Player Following Anterior Cruciate Rupture and Repair: A Case Report by Robert Mangine, Jim Tersak, Thomas Palmer, Audrey Hill-Lindsay, Bolton Patton, Marsha Eifert-Mangine, Bradley Jacobs, Angelo J Colosimo

“…Biological responses to stress, brain workload, arousal, attention and brain connectivity all improved over time…”
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Protocol to study the role of medial entorhinal cortex-basolateral amygdala circuit in context-induced retrieval of morphine withdrawal memory in mice by Yali Fu, Ting Ye, Ming Chen, Bin Lai, Ping Zheng

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Neurological sequelae of long COVID: a comprehensive review of diagnostic imaging, underlying mechanisms, and potential therapeutics by Grant McGee Talkington, Grant McGee Talkington, Paresh Kolluru, Timothy E. Gressett, Timothy E. Gressett, Saifudeen Ismael, Umar Meenakshi, Mariana Acquarone, Rebecca J. Solch-Ottaiano, Amanda White, Blake Ouvrier, Blake Ouvrier, Kristina Paré, Nicholas Parker, Amanda Watters, Nabeela Siddeeque, Brooke Sullivan, Nilesh Ganguli, Victor Calero-Hernandez, Gregory Hall, Michele Longo, Gregory J. Bix, Gregory J. Bix, Gregory J. Bix, Gregory J. Bix

“…In this review, we explore the mechanistic hypotheses of these neurological changes, which describe CNS invasion, neuroinflammation, blood-brain barrier disruption, and gut-brain axis dysregulation, along with the novel vascular disruption hypothesis that highlights endothelial dysfunction and hypoperfusion as a core underlying mechanism. …”
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Integrative analysis of immunogenic PANoptosis and experimental validation of cinobufagin-induced activation to enhance glioma immunotherapy by Yonghua Cai, Heng Xiao, Shuaishuai Xue, Peng Li, Zhengming Zhan, Jie Lin, Zibin Song, Jun Liu, Wei Xu, Qixiong Zhou, Songtao Qi, Xi’an Zhang, Ziyi Luo

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A multimodal characterization of low-dimensional thalamocortical structural connectivity patterns by Alexandra John, Meike D. Hettwer, H. Lina Schaare, Amin Saberi, Şeyma Bayrak, Bin Wan, Jessica Royer, Boris C. Bernhardt, Sofie L. Valk

“…Abstract The human thalamus is a heterogeneous subcortical structure coordinating whole-brain activity. Investigations of its internal organization reveal differentiable subnuclei, however, a consensus on subnuclei boundaries remains absent. …”
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An unconstrained four pool model analysis of proton relaxation and magnetization transfer in ex vivo white matter by Niklas Wallstein, André Pampel, Roland Müller, Carsten Jäger, Markus Morawski, Harald E. Möller

“…Abstract Understanding proton relaxation in the brain’s white matter remains an active field of magnetic resonance imaging research. …”
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Mapping chromatin remodelling in glioblastoma identifies epigenetic regulation of key molecular pathways and novel druggable targets by Claire Vinel, James Boot, Weiwei Jin, Nicola Pomella, Alexandra Hadaway, Charles Mein, Nicolae Radu Zabet, Silvia Marino

“…Abstract Background Glioblastoma is the most common and aggressive malignant brain tumour in the adult population and its prognosis is dismal. …”
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Drosophila ubiquitin-specific peptidase 14 stabilizes the PERIOD protein by regulating a ubiquitin ligase SLIMB by So Who Kang, Jung-Eun Park, Soonhyuck Ok, Minhui Um, Hyeonjeong Son, Seunghee Byun, Nayoung Park, Su Jin Lee, Thị Xuân Thùy Trần, Gyeongmin Kim, Jeonghun Yeom, Kyunggon Kim, Eun Young Kim, Min-Ji Kang

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The medial and lateral orbitofrontal cortex jointly represent the cognitive map of task space by Liwei Tan, Yidan Qiu, Lixin Qiu, Shuting Lin, Jinhui Li, Jiajun Liao, Yuting Zhang, Wei Zou, Ruiwang Huang

“…Collectively, these findings provide an account that can increase our understanding of how the brain constructs abstract cognitive maps in a task-relevant space.…”
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An analysis of the cultivation, consumption and composition of home-grown cannabis following decriminalisation in the Australian Capital Territory by Cilla Zhou, Isobel Lavender, Rebecca Gordon, Danielle McCartney, Richard C. Kevin, Miguel A. Bedoya-Pérez, Iain S. McGregor

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Task-Driven Neurophysiological qEEG Baseline Performance Capabilities in Healthy, Uninjured Division-I College Athletes. by Robert E. Mangine, Thomas G. Palmer, James A. Tersak, Michael Mark, Joseph F Clark, Marsha Eifert-Mangine, Audrey Hill-Lindsay, Brian M Grawe

“…Quantitative electroencephalography or qEEG brain mapping is a unique, real-time comprehensive assessment of brain electrical activity performed in combination with physiometrics which offers insight to neurophysiological brain-to-body function. …”
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Sex-specific influences of APOEε4 genotype on hippocampal neurogenesis and progenitor cells in middle-aged rats by Bonnie H. Lee, Melike Cevizci, Stephanie E. Lieblich, Liisa A. M. Galea

“…This research investigates how these two risk factors might interact to influence biomarkers of brain health at middle age using a rat model. Compared to healthy controls, male rats with hAPOEε4 genotype showed reduced neural stem cell-like cells and new adult-born brain cells and increased microglia (marker of inflammation in the brain) at middle age. …”
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Unravelling a mechanistic link between mitophagy defect, mitochondrial malfunction, and apoptotic neurodegeneration in Mucopolysaccharidosis VII by Nishan Mandal, Apurba Das, Rupak Datta

“…This, in turn, compromised mitochondrial function, as reflected by drastically reduced brain ATP levels. Energy depletion triggered apoptosis in neuronal as well as non-neuronal cells of the CG2135−/− fly brain, where apoptotic dopaminergic neurons were also detected. …”
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Enjoy it! Cosmetic try-on apps and augmented reality, the impact of enjoyment, informativeness and ease of use by V. Micheletto, S. Accardi, A. Fici, A. Fici, F. Piccoli, C. Rossi, M. Bilucaglia, V. Russo, V. Russo, M. Zito, M. Zito

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The zinc receptor, ZnR/GPR39, modulates taste sensitivity by regulating ion secretion in mouse salivary gland by Moran Melamed, Hila Asraf, Noa Livne, Milos Bogdanovic, Anil Shendge, Gilad Shamir, Maayan Mero, Omer Adir, Avi Schroeder, Israel Sekler, Michal Hershfinkel

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Multimodal fusion model for diagnosing mild cognitive impairment in unilateral middle cerebral artery steno-occlusive disease by Ziyi Yuan, Zhaodi Huang, Chaojun Li, Shengrong Li, Qingguo Ren, Xiaona Xia, Qingjun Jiang, Daoqiang Zhang, Qi Zhu, Xiangshui Meng, Xiangshui Meng

“…ObjectivesTo propose a multimodal functional brain network (FBN) and structural brain network (SBN) topological feature fusion technique based on resting-state functional magnetic resonance imaging (rs-fMRI), diffusion tensor imaging (DTI), 3D-T1-weighted imaging (3D-T1WI), and demographic characteristics to diagnose mild cognitive impairment (MCI) in patients with unilateral middle cerebral artery (MCA) steno-occlusive disease.MethodsThe performances of different algorithms on the MCI dataset were evaluated using 5-fold cross-validation. …”
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Imaging lipid rafts reveals the principle of ApoE4-induced Aβ upregulation in human neurons by Se-In Lee, Heejin Lim, Na Yeon Kim, Jichang Yu, Joonho Cho, Hyein Lee, Dae Won Moon, Jinsoo Seo

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Association of blood cadmium and physical activity with mortality: A prospective cohort study by Yilin Chen, Cien Zhen, Lin Zeng, Hongliang Feng, Jinyu Wang, Qi Yong H. Ai, Sizhi Ai, Jihui Zhang, Yannis Yan Liang, Huachen Xue, Yujing Zhou

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