Morphological Neuroimaging Biomarkers for Tinnitus: Evidence Obtained by Applying Machine Learning by Yawen Liu, Haijun Niu, Jianming Zhu, Pengfei Zhao, Hongxia Yin, Heyu Ding, Shusheng Gong, Zhenghan Yang, Han Lv, Zhenchang Wang

“…For each subject, the gray matter volume of 61 brain regions was extracted as an original feature pool. …”
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Differences in central dopamine, but not serotonin, activity and welfare associated with age but not with preening cup use in commercial grow-out Pekin duck barns by M.M. Bergman, J.M. Schober, R. Novak, A. Grief, C. Plue, D. Frey, H. Parnin, G.S. Fraley

“…The brains were hemisected and dissected in three brain areas: caudal mesencephalon (CM), rostral mesencephalon (RM), and diencephalon (DI). …”
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Impairment of cocaine-mediated behaviours in mice by clinically relevant Ras-ERK inhibitors by Alessandro Papale, Ilaria Maria Morella, Marzia Tina Indrigo, Rick Eugene Bernardi, Livia Marrone, Francesca Marchisella, Andrea Brancale, Rainer Spanagel, Riccardo Brambilla, Stefania Fasano

“…Ras-ERK signalling in the brain plays a central role in drug addiction. However, to date, no clinically relevant inhibitor of this cascade has been tested in experimental models of addiction, a necessary step toward clinical trials. …”
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Automated cell annotation in multi-cell images using an improved CRF_ID algorithm by Hyun Jee Lee, Jingting Liang, Shivesh Chaudhary, Sihoon Moon, Zikai Yu, Taihong Wu, He Liu, Myung-Kyu Choi, Yun Zhang, Hang Lu

“…Previously, we developed an automated cell identification method called CRF_ID and demonstrated its high performance in Caenorhabditis elegans whole-brain images (Chaudhary et al., 2021). However, because the method was optimized for whole-brain imaging, comparable performance could not be guaranteed for application in commonly used C. elegans multi-cell images that display a subpopulation of cells. …”
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Anatomical and Functional MRI Changes after One Year of Auditory Rehabilitation with Hearing Aids by M. R. Pereira-Jorge, K. C. Andrade, F. X. Palhano-Fontes, P. R. B. Diniz, M. Sturzbecher, A. C. Santos, D. B. Araujo

“…Our data provide the first evidence that one year of HA use is related to functional and anatomical brain changes, notably in auditory and language systems, extending to multimodal cortices.…”
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Amyloid-β and heart failure in Alzheimer’s disease: the new vistas by Hayder M. Al-Kuraishy, Ghassan M. Sulaiman, Hamdoon A. Mohammed, Sohaib G. Mohammed, Ali I. Al-Gareeb, Ali K. Albuhadily, Retaj A. Dawood, Amer Al Ali, Mohammed H. Abu-Alghayth

“…Of note, Aβ is not only originated from the brain but also produced peripherally and, via the blood–brain barrier (BBB), can accumulate in the brain and result in the development of AD. …”
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In Vivo Structural and Functional Abnormalities of the Striatums Is Related to Decreased Astrocytic BDNF in Itpr2-/- Mice Exhibiting Depressive-Like Behavior by Shanmei Zeng, Kai Liu, Jingyu Zhang, Chunhui Chen, Yihua Xu, Yulan Wu, Yanjia Deng, Xuegang Sun, Ge Wen, Linlin Jing

“…Voxel-based morphometry and seed-based voxel-wise functional connectivity (FC) were, respectively, calculated to assess the gray matter volume and the functional activities of the brain in vivo. Second, the sample of relevant changed brain regions was extracted to detect the expression of BDNF. …”
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The Left Superior Longitudinal Fasciculus within the Primary Sensory Area of Inferior Parietal Lobe Plays a Role in Dysgraphia of Kana Omission within Sentences by Nobusada Shinoura, Akira Midorikawa, Toshiyuki Onodera, Ryozi Yamada, Yusuke Tabei, Yasumitsu Onda, Chihiro Itoi, Seiko Saito, Kazuo Yagi

“…Functional neurological changes after surgery combined with diffusion tensor imaging (DTI) tractography can directly provide evidence of anatomical localization of brain function. Using these techniques, a patient with dysgraphia before surgery was analyzed at our hospital in 2011. …”
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Gestational Choriocarcinoma Presenting with Lacrimal Gland Metastasis: A First Reported Case by Naushad A. B. Ahamed, Khalid Sait, Nisreen Anfnan, Khader Farwan, S. H. M. Nizamuddin, Saleh S. Baeesa

“…A metastatic imaging screening revealed multiple metastases in the lungs, brain, and adrenal gland, in addition to the choroid and lacrimal gland. …”
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PKA Inhibitor H89 (N-[2-p-bromocinnamylamino-ethyl]-5-isoquinolinesulfonamide) Attenuates Synaptic Dysfunction and Neuronal Cell Death following Ischemic Injury by Juhyun Song, So Yeong Cheon, Won Taek Lee, Kyung Ah Park, Jong Eun Lee

“…The data suggest that H89 may contribute to brain recovery after ischemic stroke by regulating neuronal death and proteins related to synaptic plasticity.…”
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Nanoparticle Therapy Is a Promising Approach in the Management and Prevention of Many Diseases: Does It Help in Curing Alzheimer Disease? by Lamyaa M. Kassem, Nada A. Ibrahim, S. Ayesha Farhana

“…Treatment of brain diseases is always limited by the physiological nature of the highly selective blood-brain barrier (BBB) and the electrostatic charge of the nanoporous extracellular matrix. …”
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Correlation between Traits of Emotion-Based Impulsivity and Intrinsic Default-Mode Network Activity by Jizheng Zhao, Dardo Tomasi, Corinde E. Wiers, Ehsan Shokri-Kojori, Şükrü B. Demiral, Yi Zhang, Nora D. Volkow, Gene-Jack Wang

“…These findings suggest an association between intrinsic brain activity and impulsive behaviors in healthy humans.…”
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BACE1 Is Necessary for Experience-Dependent Homeostatic Synaptic Plasticity in Visual Cortex by Emily Petrus, Hey-Kyoung Lee

“…Studies over the past few decades suggest that Aβ is produced in an activity-dependent manner and has physiological relevance to normal brain functions. Similarly, physiological functions for β- and γ-secretases, the two key enzymes that produce Aβ by sequentially processing the amyloid precursor protein (APP), have been discovered over recent years. …”
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Drug resistant epilepsy as the consequence of inadequate control of type 1 diabetes by Ewa M. Sokolewicz, Kamil Dzwilewski, Natalia Omieczyńska, Marta Zawadzka, Maria Mazurkiewicz-Bełdzińska

“…EEG revealed generalized slow brain activity, without obvious epileptiform. Boy was provided with a variety of antiepileptic drugs. …”
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Effects of Low Concentration of Glyphosate-Based Herbicide on Genotoxic, Oxidative, Inflammatory, and Behavioral Meters in Danio rerio (Teleostei and Cyprinidae) by Eduardo Bortolon Ribas, Gustavo Colombo Dal-Pont, Ariana Centa, Marcos Otávio Bueno, Ricardo Cervini, Rosana Claudio Silva Ogoshi, Claudriana Locatelli

“…Fish were exposed to different concentrations of GBH (0, 50, 250, and 500 µg/L) for 96 hours. Brain, liver, and blood were collected for biochemical and genotoxicity analyses, and behavioral tests were performed. …”
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Ex Vivo Antioxidant Activity of Selected Medicinal Plants against Fenton Reaction-Mediated Oxidation of Biological Lipid Substrates by Namratha Pai Kotebagilu, Vanitha Reddy Palvai, Asna Urooj

“…Results indicated highest antioxidant potential by 80% methanol extract of Canthium parviflorum (97.55%), methanol extract of Andrographis paniculata (72.15%), and methanol extract of Canthium parviflorum (49.55%) in cholesterol, low-density lipoprotein, and brain, respectively. The polyphenol and flavonoid contents of methanol extract of Andrographis paniculata in cholesterol (r=0.816) and low-density lipoprotein (r=0.948) and Costus speciosus in brain (r=0.977, polyphenols, and r=0.949, flavonoids) correlated well with the antioxidant activity. …”
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Measuring Measuring iron concentration in the blood samples of some autistic children from Baghdad City by Ezzuldin sulaiman, Hind Suhail Abdulhay

“…Iron is one of the heavy metals around which there is much controversy regarding their role as neurotoxins in the development of autism, its excess in the brain may cause Alzheimer's disease or Parkinson's disease, while iron deficiency in the blood may increase levels of other heavy metals in the blood and brain, such as cadmium and lead. …”
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Melatonin influence on miRNA expression in sperm, hypothalamus, pre-frontal cortex and cerebellum of Wistar rats. by Mísia Helena da Silva Ferro, Ingrid Morante, Fernanda Akane Nishino, Camila Estevam, Fernanda Gaspar do Amaral, José Cipolla-Neto, Taiza Stumpp

“…MicroRNAs are known to participate in a wide variety of mechanisms in basically all cells and tissues, including the brain and the sperm cells, which are known, respectively, to present 70% of all identified microRNAs and to transfer these molecules to the embryo. …”
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LncRNA-PVT1 enhances glucose metabolism of pediatric low-grade glioma cells through sponging miR-187-3p by Beibei Li, Zijian Feng, Yanyan Zheng

“…Studies have revealed critical roles of long non-coding RNAs (lncRNAs) in brain tumor progressions. Here, we aimed to investigate the clinical roles and molecular mechanisms of lncRNA PVT1 in PLGG. …”
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Age-Related Reduced Somatosensory Gating Is Associated with Altered Alpha Frequency Desynchronization by Chia-Hsiung Cheng, Pei-Ying S. Chan, Sylvain Baillet, Yung-Yang Lin

“…There has been evidence showing a relationship between brain oscillations and cortical evoked excitability. …”
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