How will developmental neuroimaging contribute to the prediction of neurodevelopmental or psychiatric disorders? Challenges and opportunities by Koraly Pérez-Edgar, Mary Dozier, Rebecca Saxe, Katherine E. MacDuffie

“…Successful developmental neuroimaging efforts require interdisciplinary expertise to ground scientific questions in knowledge of human development, modify and create technologies and data processing pipelines suited to the young brain, and ensure research procedures meet the needs and protect the interests of young children and their caregivers. …”
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Pulsed Low-Intensity Focused Ultrasound (LIFU) Activation of Ovarian Follicles by Yan Xiao, Lixia Yang, Yicong Wang, Yu Wang, Yuning Chen, Wenhan Lu, Zhenle Pei, Ruonan Zhang, Yao Ye, Xiaowei Ji, Suying Liu, Xi Dong, Yonghua Xu, Yi Feng

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Isolation of Rat and Human Hippocampal Neuron Fractions in a Discontinuous Density Gradient by John Graham

“…A discontinuous iodixanol gradient permits both the production of a viable concentrated suspension of neurons and purification from other brain tissue elements. The gradient that is described in this Protocol Article is applicable to brain tissue from rat and also from human biopsy specimens.…”
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Ginseng exhibits adaptogenic-like activity in mice exposed to hypoxic-anoxic stress through activation of antioxidant/BDNF protective mechanisms and inhibition of pro-inflammatory... by James Olukayode Oni, Divine Oluwaferanmi Oyenekan, Yetunde Olamide Olayemi, Osarugue Christabel Irabor, Precious Ogbuji, McCarthy Oritseweyinmi Tova, Paul Ademola Adeleke, Gbemisayo Adetomiwa Abbas, Solomon Umukoro

“…Introduction: Hypoxic-anoxic stress causes severe injury to the brain cells resulting in various neuropathological complications. …”
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Cranial reconstruction utilizing polymeric implants in two different designs: finite element investigation by Yomna H. Shash

“…In addition, CFR-PEEK 60% implants produced the lowest values of stress, strain, and total deformation on the skull and brain compared to titanium implants, unlike PEEK implants. …”
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Investigating the relationship between inflammatory cytokines and adolescent depression: a comparative analysis by Mengqi Liu, Mengqi Liu, Jie Tang, Jie Tang, Gaoyang Xu, Gaoyang Xu, Xu Chen, Xu Chen, Kun Fang, Fan He, Fan He, Yi Zheng, Yi Zheng

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High Quality–Factor All–Dielectric Metacavity for Label–Free Biosensing by Yuqiao Zheng, Jiacheng Sun, Yaqing Ma, Hongyong Zhang, Zhen Cui, Giannis G. Paschos, Xixi Song, Ying Tao, Pavlos Savvidis, Wei Kong, Liaoyong Wen, Sumin Bian, Mohamad Sawan

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Nanopore-based random genomic sampling for intraoperative molecular diagnosis by Francesco E. Emiliani, Abdol Aziz Ould Ismail, Edward G. Hughes, Gregory J. Tsongalis, George J. Zanazzi, Chun-Chieh Lin

“…Despite recent advances in intraoperative methylation classifications of brain tumors, accuracy may be compromised by low tumor purity. …”
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Sleep-Aiding Effect of Casein-Derived Peptide TPTLN and Its Underlying Mechanism by DENG Shijie, LIU Ling, HUANG Ju, FENG Fengqin, ZHAO Minjie, DU Juan

“…Results: Compared with the control group, TPTLN and sodium pentobarbital synergistically increased the sleep onset rate to 100%, significantly shortened the sleep latency by 31.7% (P < 0.05), and extended the sleep duration 2.1 times (P < 0.05); increased the GABA/Glu ratio in the serum and brain tissue by 68.8% and 19.3%, respectively and significantly improved the excitation/inhibition imbalance (P < 0.001, P < 0.000 1) as evidenced by a 49.4% increase in the serum GABA level (P < 0.001), a 7.6% increase in the brain 5-HT level, and a 24.3% and 23.4% decrease in the brain levels of cortisol and NE (P < 0.05); and significantly up-regulated the expression levels of the GABAA-α1 and 5-HT1A genes 1.5 and 1.3 times, respectively (P < 0.01, P < 0.05). …”
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Elevation of ganglioside degradation pathway drives GM2 and GM3 within amyloid plaques in a transgenic mouse model of Alzheimer's disease by Wenxuan Wang, Sarah J. Myers, Nikita Ollen-Bittle, Shawn N. Whitehead

“…This study utilized a dual-resolution approach in combination with whole-brain imaging for comprehensive detection of ganglioside expression across neuroanatomical regions via high-resolution imaging of the cerebral cortex and hippocampus to investigate plaque-associated ganglioside alterations. …”
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Genetic context modulates aging and degeneration in the murine retina by Olivia J. Marola, Michael MacLean, Travis L. Cossette, Cory A. Diemler, Amanda A. Hewes, Alaina M. Reagan, Jonathan Nyandu Kanyinda, Daniel A. Skelly, Gareth R. Howell

“…Abstract Background Age is the principal risk factor for neurodegeneration in both the retina and brain. The retina and brain share many biological properties; thus, insights into retinal aging and degeneration may shed light onto similar processes in the brain. …”
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Auditory decision-making deficits after permanent noise-induced hearing loss by Madeline P. Berns, Genesis M. Nunez, Xingeng Zhang, Anindita Chavan, Klavdia Zemlianova, Todd M. Mowery, Justin D. Yao

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The Effect of Long-Term Intranasal Serotonin Treatment on Metabolic Parameters and Hormonal Signaling in Rats with High-Fat Diet/Low-Dose Streptozotocin-Induced Type 2 Diabetes by Kira V. Derkach, Vera M. Bondareva, Oxana V. Chistyakova, Lev M. Berstein, Alexander O. Shpakov

“…In the last years the treatment of type 2 diabetes mellitus (DM2) was carried out using regulators of the brain signaling systems. In DM2 the level of the brain serotonin is reduced. …”
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Translaminar synchronous neuronal activity is required for columnar synaptic strengthening in the mouse neocortex by John Vargas-Ortiz, Lin Lin, Vena K. Martinez, Rong-jian Liu, Rachel Babij, Zhe Ran S. Duan, Sam Wacks, Liyuan Sun, Amanda Wang, Sajida Khan, John Lee Soto-Vargas, Natalia V. De Marco García, Alicia Che

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Immigration modulates audiovisual emotional processing in adults: is this really an influence of the host culture? by Anna K. Nakamura, Anna K. Nakamura, Hisako W. Yamamoto, Hisako W. Yamamoto, Sachiko Takagi, Tetsuya Matsuda, Hiroyuki Okada, Chiaki Ishiguro, Chiaki Ishiguro, Akihiro Tanaka

“…Additionally, immigrants with a longer stay showed a higher response in the posterior superior temporal gyrus, a brain region associated with audiovisual emotional integration, when processing emotionally congruent faces and voices.DiscussionThese modifications imply that immigrants from Western cultures tend to rely even less on voices, in contrast to the tendency of voice-dominance observed in native Japanese people. …”
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Motion feature extraction using magnocellular-inspired spiking neural networks for drone detection by Jiayi Zheng, Jiayi Zheng, Yaping Wan, Xin Yang, Hua Zhong, Minghua Du, Gang Wang, Gang Wang

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The Insulin Regulatory Network in Adult Hippocampus and Pancreatic Endocrine System by Masanao Machida, Shin Fujimaki, Ryo Hidaka, Makoto Asashima, Tomoko Kuwabara

“…Hormonal signals from the pancreatic islets influence the regulation of energy homeostasis by the brain, and the brain in turn influences the secretions of the islets. …”
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A Novel Metabolic Connectome Method to Predict Progression to Mild Cognitive Impairment by Min Wang, Zhuangzhi Yan, Shu-yun Xiao, Chuantao Zuo, Jiehui Jiang

“…The metabolic connectome may help to identify brain metabolic dysfunction and build a clinically applicable biomarker to predict the MCI progression.…”
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Detection of Amylin-β-amyloid Hetero-Oligomers by Enzyme-Linked Immunosorbent Assay by Noah Leibold, Deepak Kotiya, Nirmal Verma, Florin Despa

“…It readily crosses the blood–brain barrier and synergistically forms mixed amyloid plaques with β-amyloid (Aβ) in brain parenchyma. …”
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Recurrent Painful Ophthalmoplegic Neuropathy and Oculomotor Nerve Schwannoma: A Pediatric Case Report with Long-Term MRI Follow-Up and Literature Review by Maria Giuseppina Petruzzelli, Mariella Margari, Flora Furente, Maria Carmela Costanza, Anna Rosi Legrottaglie, Franca Dicuonzo, Lucia Margari

“…We report a 16-year-old boy with a 7-year follow-up and multiple brain MRI data, previously diagnosed as OM. The last brain MRI, performed during an acute phase of oculomotor paresis with ipsilateral headache, showed a nodular lesion described as schwannoma of III cranial nerve. …”
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