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  1. 6501

    Exploration of linear and interpretable models for quantification of cell parameters via contactless short-wave infrared hyperspectral sensing by Anjana Hevaganinge, Eva Lowenstein, Anna Filatova, Mihir Modak, Nandi Thales Mogo, Bryana Rowley, Jenny Yarmowsky, Joshua Ehizibolo, Ravidu Hevaganinge, Amy Musser, Abbey Kim, Anthony Neri, Jessica Conway, Yiding Yuan, Maurizio Cattaneo, Sui Seng Tee, Yang Tao

    Published 2025-01-01
    “…Further, most practitioners find it difficult to confidently adapt black box chemometric models that are difficult to troubleshoot in high-stakes applications such as biopharmaceutical manufacturing. …”
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    Article
  2. 6502

    Evaluating Avacopan in the Treatment of ANCA-Associated Vasculitis: Design, Development and Positioning of Therapy by van Leeuwen JR, Quartuccio L, Draibe JB, Gunnarson I, Sprangers B, Teng YKO

    Published 2025-01-01
    “…Jolijn R van Leeuwen,1 Luca Quartuccio,2 Juliana Bordignon Draibe,3 Iva Gunnarson,4 Ben Sprangers,5 Y K Onno Teng1 1Center of Expertise for Lupus-, Vasculitis- and Complement-Mediated Systemic Diseases (Luvacs), Department of Internal Medicine - Nephrology Section, Leiden University Medical Center, Leiden, the Netherlands; 2Division of Rheumatology, Department of Medicine, University of Udine, Udine, Italy; 3Department of Nephrology, Bellvitge University Hospital, Bellvitge Biomedical Research Institute (IDIBELL), Hospitalet de Llobregat, Barcelona, Spain; 4Division of Rheumatology, Department of Medicine, Karolinska Institutet, Stockholm, Sweden; Karolinska University Hospital, Stockholm, Sweden; 5Department of Nephrology, Ziekenhuis Oost Limburg Genk, Genk, BelgiumCorrespondence: Y K Onno Teng, Department of Nephrology, Leiden University Medical Center (LUMC), P.O. Box 9600, Leiden, 2300 RC, the Netherlands, Tel +31-71-5262148, Fax +31-71-5266868, Email Y.K.O.Teng@lumc.nlAbstract: Recently, avacopan has been approved for the treatment of ANCA-associated vasculitis (AAV). …”
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  3. 6503

    Effects of bronchoscopic alveolar lavage–assisted mechanical ventilation on postoperative pulmonary infection and inflammatory factors in patients undergoing lung cancer surgery by Hui Zhu, Haiyang Lu

    Published 2024-07-01
    “…The levels of inflammatory markers (high-sensitivity C-reactive protein, procalcitonin, tumor necrosis factor α, high-mobility group box 1, interleukin 6, and macrophage inflammatory protein 1α) in peripheral blood were decreased regardless of the treatment method (all P <⁠0.05). …”
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  4. 6504

    Kinematics, Kinetics and Muscle Activity Analysis during Single-leg Drop-jump Landing Followed by an Unanticipated Task: Focusing on Differences in Neurocognitive Function by Satoshi Shibata, Masahiro Takemura, Shumpei Miyakawa

    Published 2023-10-01
    “…Three-dimensional motion analysis was employed for the analysis during the experimental task of a single-leg drop-jump followed by an unanticipated landing task from a 30-cm high box. Joint angular changes of the trunk, pelvis, hip, and knee were calculated within the interval from initial contact (IC) to 40ms. …”
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  5. 6505

    Optimal Vase Solution for <i>Gerbera hybrida</i> Cut Flower Keeping Fresh by Activating SA and Cytokinin Signaling and Scavenging Reactive Oxygen Species by Chaoshui Xia, Yiyang Cao, Weixin Gan, Huifeng Lin, Huayang Li, Fazhuang Lin, Zhenhong Lu, Weiting Chen

    Published 2024-12-01
    “…We used chitosan (COS), calcium chloride (CaCl<sub>2</sub>), and citric acid (CA) as the main ingredients of the vase solution and determined the OS ratio of 104 mg/L of COS, 92 mg/L of CA, and 93 mg/L of CaCl<sub>2</sub> using the Box–Behnken design-response surface method (BBD-RSM). …”
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  6. 6506

    Tomato yellow leaf curl virus detection based on cross-domain shared attention and enhanced BiFPN by Henghui Mo, Linjing Wei

    Published 2025-03-01
    “…Moreover, the introduction of Inner-CIOU with a scale factor-controlled auxiliary bounding box optimizes the precision and regression efficiency in detecting small target features. …”
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  7. 6507

    Biomimetic polydopamine loaded with janus kinase inhibitor for synergistic vitiligo therapy via hydrogel microneedles by Chunying Li, Wenwen Wang, Junyi Shao, Sen Zhou, Xiaolin Ji, Youxia Xi, Qiuyang Xu, Yuhan Huang, Jingle Wang, Yilin Wan, Zhiming Li

    Published 2025-01-01
    “…Under oxidative stress, the apoptotic melanocytes expose self-antigens and release high mobility group box 1 (HMGB1), triggering autoimmune activation and recruiting CD8+ T cells. …”
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  8. 6508

    Assessing the Feasibility of Drone‐Mediated Vaccine Delivery: An Exploratory Study by Sumit Aggarwal, Prakamya Gupta, Sivaraman Balaji, Saurabh Sharma, Ajoy Kanti Ghosh, Simmy, Balram Bhargava, Samiran Panda

    Published 2025-01-01
    “…Notably, the vaccine carrier box was able to maintain a recommended temperature of 3°C–4°C throughout the transportation process, and there is no impact of vibration on the physical integrity and leakage of the vaccine vials during flight. …”
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  9. 6509

    Ontologies in modelling and analysing of big genetic data by N. L. Podkolodnyy, O. A. Podkolodnaya, V. A. Ivanisenko, M. A. Marchenko

    Published 2025-01-01
    “…One of the main problems of deep learning is the lack of interpretability, since neural networks often function as “black boxes” unable to explain their decisions. This paper describes approaches to creating methods for interpreting deep learning models and presents two examples of self-explanatory ontology-based deep learning models: (1) Deep GONet, which integrates Gene Ontology into a hierarchical neural network architecture, where each neuron represents a biological function. …”
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  10. 6510

    A blind navigation guide model for obstacle avoidance using distance vision estimation based YOLO-V8n by EBERE CHIDI, Edward Anoliefo, Collins Udanor, Asogwa Tochukwu Chijindu, Lois Onyejere Nwobodo

    Published 2025-02-01
    “…Furthermore, the issue of bounding box overlap in the model was addressed by applying a Wise Intersection over Unit (WIoU) loss function. …”
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  11. 6511

    Association between transcription factors expression and growth patterns of nonfunctioning pituitary adenomas by Jiakun Xu, Shaolin Zhang, Weijie Su, Jia Yang, Lixuan Yang, Xixi Li

    Published 2025-01-01
    “…Abstract Transcription factors (TFs), including steroidogenic factor-1 (SF-1), T-box transcription factor (TPIT) and pituitary transcription factor–1 (PIT-1), play a pivotal role in the cytodifferentiation of adenohypophysis. …”
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  12. 6512
  13. 6513
  14. 6514
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  18. 6518
  19. 6519
  20. 6520