Complex treatment for dry eye disease in intermediate uveitis by E.B. Tatarnikova, O.I. Krivosheina

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Predicting Cognitive Decline in Parkinson’s Disease with Mild Cognitive Impairment: A One-Year Observational Study by Pei-Hao Chen, Fang-Yu Cheng, Shih-Jung Cheng, Jin-Siang Shaw

“…Initial Clinical Dementia Rating—Sum of Boxes score was a better predictor of future cognitive decline than MMSE in PD-MCI. …”
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Production, Purification, and Characterization of Thermostable α-Amylase Produced by Bacillus licheniformis Isolate AI20 by Yasser R. Abdel-Fattah, Nadia A. Soliman, Nabil M. El-Toukhy, Hamada El-Gendi, Rania S. Ahmed

“…Thereafter, the response surface methodology (RSM) was adopted to acquire the best process conditions among the selected variables, where a three-level Box-Behnken design was employed to create a polynomial quadratic model correlating the relationship between the three variables and α-amylase activity. …”
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Fabrication and In Vivo Evaluation of In Situ pH-Sensitive Hydrogel of Sonidegib–Invasomes via Intratumoral Delivery for Basal Cell Skin Cancer Management by Maha M. Ghalwash, Amr Gamal Fouad, Nada H. Mohammed, Marwa M. Nagib, Sherif Faysal Abdelfattah Khalil, Amany Belal, Samar F. Miski, Nisreen Khalid Aref Albezrah, Amani Elsayed, Ahmed H. E. Hassan, Eun Joo Roh, Shaimaa El-Housiny

“…Methods: Numerous S-INV formulations were developed using Box–Behnken Design Expert and tested before settling on the optimum S-INV formulation. …”
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Enhancing Qualitative Research: The Use of Design Probes and Cooking Sessions Deepens the Understanding of 9- to 11-Year-Old Children’s Food Perceptions by Lotte Pater, Elizabeth H. Zandstra, Vincenzo Fogliano, Bea L. P. A. Steenbekkers

“…In the first stage, children received a design probe box with assignments to be performed individually at home, aiming at gathering data about their everyday life and experiences in a familiar, informal setting. …”
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The influence of meteorological factors on the technical performance of football teams during matches by Yonghan Zhong, Shaoliang Zhang, Qing Yi, Miguel Ángel Gómez Ruano

“…Two technical indicators, “dribbles won” and “shots from the 6-yard box,” were both significantly influenced by two meteorological factors. …”
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Gene Editing in Pluripotent Stem Cells and Their Derived Organoids by Hang Zhou, Yun Wang, Li-Ping Liu, Yu-Mei Li, Yun-Wen Zheng

“…Are the tools for rewriting the code of life a boon to humanity or a Pandora’s box? These technologies raise concerns regarding ethical issues, unexpected mutations, viral infection, etc. …”
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Sustainability by extraction of bioactive compounds from onion seeds by Mestour, Selma, Meniai, Abdeslam-Hassen, Melloul, Sarra, Louaer, Mehdi

“…To achieve this, the effects of four key operating parameters like pressure, temperature, particle size and CO2 mass flowrate were investigated in ranges of [150, 250 bars], [35, 65 °C], [0.25, 0.85 mm] and [50, 100 g/min], respectively, using a Box-Behnken experimental design, for a constant extraction time of 3 h. …”
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Seismic Performance of Offshore Piers under Wave Impact and Chloride Ion Corrosion Environment by Yin Gu, Anhua Yu, Xiaolong Zhang

“…Firstly, through the scale model test of tsunami wave flume, the wave force of box girder structures and piers under different tsunami wave conditions is measured. …”
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Optimization of Tillage Operation Parameters to Enhance Straw Incorporation in Rice-Wheat Rotation Field by Sagni B. Miressa, Qishuo Ding, Yinian Li, Edwin O. Amisi

“…In the research, the response surface design employed was the Box–Behnken Design (BBD). The optimal operating parameters were 14.23 cm of plowing depth, 297.6 rpm for the rotary blades, and 3.23 km/h for forward speed. …”
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Hybrid Method of Modal Analysis and Laser Shock Scanning to Visualize the Pyroshock Propagation in a Tension Joint by Yong-Woon Kim, Jae-Kyeong Jang, Jung-Ryul Lee, Hak-Seong Gim

“…For the proof of concept of the proposed method, we performed experiments of explosive bolt-induced shock and pyrolock-induced shock in the open-box-type tension joint and compared the hybrid simulation results with actual pyroshock. …”
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PAX6 enhances Nanog expression by inhibiting NOTCH signaling to promote malignant properties in small cell lung cancer cells by Xiao-Fang Guo, Ling-Ling Wang, Fei-Meng Zheng, He-Ping Li

“…The aberrant regulation of Paired box 6 (PAX6) expression has been proposed to play an important oncogenic role in several cancer types. …”
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Comprehensive Analysis of the Role of SLC2A3 on Prognosis and Immune Infiltration in Head and Neck Squamous Cell Carcinoma by Manru Chu, Ke Zheng, Xiaojie Li, Zhiqiang Luo, Xin Yang, Changbo Wei

“…Immune checkpoints and ESTIMATE score were analyzed via the SangerBox database. Results. SLC2A3 expression was upregulated in HNSCC tissues compared to normal tissues. …”
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Feedback loop centered on MAF1 reduces blood–brain barrier damage in sepsis-associated encephalopathy by Xuebiao Wei, Wenqiang Jiang, Zhonghua Wang, Yichen Li, Yuanwen Jing, Yongli Han, Linqiang Huang, Shenglong Chen

“…Interference with forkhead box O1 (FOXO1) inhibited MAF1 expression and activated the RIG-I/IRF3 signaling pathway, while MAF1 overexpression promoted PTEN expression, decreased cell apoptosis, and normalized autophagy. …”
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RAGE and its ligands in breast cancer progression and metastasis by Madalina Coser, Bogdan Mihai Neamtu, Bogdan Mihai Neamtu, Bogdan Pop, Bogdan Pop, Calin Remus Cipaian, Calin Remus Cipaian, Maria Crisan, Maria Crisan

“…Recent studies reported an interplay between the receptor for advanced glycation end products (RAGE) and its ligands, S100 protein group, advanced glycation end products (AGEs) and high-mobility group box 1 protein (HMGB1) and breast cancer growth and metastasis.Materials and methodsWe used articles available in the NCBI website database PubMed to write this scoping review. …”
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Optimization of pyrite cinder strengthening continuous acid decomposition of ilmenite by response surface methodology by Congxue Tian

“…Using pyrite cinder as strengthening activator, the continuous acid decomposition conditions for ilmenite were optimized by using response surface methodology based on Box-Behnken design method. The acid decomposition conditions such as acid ilmenite ratio, acid concentration and pyrite cinder dosage mainly affected the reaction temperature, reaction equilibrium, reaction velocity, volatilization degree of water and sulfuric acid, ultimately affecting the solidification degree of the products and reaction yields. …”
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Study on the Application of a Photocatalytic Titanium Dioxide Coating on Glass Beads for the Treatment of Perfluorooctane Sulfonic Acid by Dao Duy Nam, Cao Thi Hong Hanh, Nghiem Minh Huyen, Dieu-Anh Van, Ha Vinh Hung, Vu Minh Trang, Vu Quang Minh, Nguyen Bich Ngoc, Vu Thi Thu Ha, Huynh Trung Hai

“…The study employed the response surface method (RSM) using the Box–Behnken design (BBD) to optimize treatment conditions at a PFOS concentration of 0.1 mg/L. …”
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Automatic Adaptive Algorithm for Delineation of Cerebral-Spinal Fluid Regions for Non-contrast Magnetic Resonance Imaging Volumetry and Cisternography in Mice by Ryszard Gomolka

“…Key steps include computing a bounding box enclosing the brain parenchyma in three dimensions, applying an adaptive intensity threshold, and refining CSF regions independently in sagittal, axial, and coronal planes. …”
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BUSClean: Open-source software for breast ultrasound image pre-processing and knowledge extraction for medical AI. by Arianna Bunnell, Kailee Hung, John A Shepherd, Peter Sadowski

“…Adaptation of the lesion caliper detection method to account for a type of caliper specific to the case study demonstrates the intended use of BUSClean in new data distributions and improved performance in lesion caliper detection from 43.3% and 93.3% out-of-the-box to 92.1% and 92.3% sensitivity and specificity, respectively. …”
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SOX7 is involved in polyphyllin D-induced G0/G1 cell cycle arrest through down-regulation of cyclin D1 by Zheng Bin, Wang Gang, Gao Wenbo, Wu Qiquan, Zhu Weizhi, Weng Guobin

“…Our previous study showed that the sex-determining region Y-box 7 (SOX7) was low-expressed and served as a tumor suppressor in PCa cells. …”
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