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5121
Exclusion Limits on a Scalar Decaying to Photons and Distinguishing Its Production Mechanisms
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5122
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5123
Recording dan Pencarian Silsilah Kambing Perah Menggunakan Algoritme Depth First Search
Published 2022-02-01“…Waterfall method has its own advantages Each process has its own specifications, so that a system can be developed according to what is desired. The results of black-box recording system testing and pedigree search of goat data show the functional system went as expected. …”
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5124
Social Anxiety Symptoms in The Visually Impaired Versus Healthy Control: Saudi Arabian Samples
Published 2025-01-01“…Sultan Saad Alsubaie Department of Psychiatry, Armed Forces Hospital, Khamis Mushayt, Saudi ArabiaCorrespondence: Sultan Saad Alsubaie, Consultant Psychiatrist, psychiatry department, Armed Forces Hospital Southern Region, P.O. Box 101, Khamis Mushayt, Saudi Arabia, Tel +96-6503799971, Email dr.slt4444@gmail.comPurpose: This study aims to compare self-esteem and social anxiety disorder (SAD) symptoms levels between visually impaired and sighted individuals, and to explore the relationship between social anxiety and various sociodemographic factors.Materials and Methods: A case-control study was conducted from March to June 2017 in Riyadh, Saudi Arabia, involving 62 participants (24 visually impaired and 38 sighted). …”
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5125
IL-34 aggravates myocardial ischemia-reperfusion injury by upregulating the HMGB1-IL-17A-IL-6 axis through the JAK signaling pathway.
Published 2025-01-01“…We found that IL-34 pretreatment increased the expression of inflammatory cytokines, including high mobility group Box 1 (HMGB1), IL-17A, and IL-6; the expression of the apoptosis protein cleaved caspase-3; and the Bcl-2/Bax ratio within the ischemic myocardium. …”
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5126
A TEI Customization for Writing TEI Customizations
Published 2019-11-01“…This is because the TEI Guidelines are not meant to be used out of the box—every TEI project is expected to customize the TEI. …”
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5127
ALL-Net: integrating CNN and explainable-AI for enhanced diagnosis and interpretation of acute lymphoblastic leukemia
Published 2025-01-01“…These findings highlight the effectiveness of CNNs in accurately detecting ALL from PBS images and emphasize the importance of addressing data imbalance issues through appropriate preprocessing techniques at the same time demonstrating the usage of XAI in solving the black box approach of the deep learning models. The proposed ALL-Net outperformed EfficientNet, MobileNetV3, VGG-19, Xception, InceptionV3, ResNet50V2, VGG-16, and NASNetLarge except for DenseNet201 with a slight variation of 0.5%. …”
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5128
Moving beyond post hoc explainable artificial intelligence: a perspective paper on lessons learned from dynamical climate modeling
Published 2025-02-01“…<p>AI models are criticized as being black boxes, potentially subjecting climate science to greater uncertainty. …”
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5129
Bi-level data-driven enterprise-wide optimization with mixed-integer nonlinear scheduling problems
Published 2025-03-01“…Our study further evaluates the efficacy of using local, NOMAD (Nonlinear Optimization by Mesh Adaptive Direct Search), and a global data-driven optimizer, ARGONAUT (AlgoRithms for Global Optimization of coNstrAined grey-box compUTational), within the DOMINO framework and characterize their performance both in terms of solution quality and computational expense. …”
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5130
Machine learning analysis of pathological images to predict 1-year progression-free survival of immunotherapy in patients with small-cell lung cancer
Published 2024-02-01“…We trained a model to predict 1-year progression-free survival (PFS) using pathological images (H&E, programmed cell death-ligand 1 (PD-L1), and double immunohistochemical assay (cluster of differentiation 8 (CD8) and forkhead box P3 (FoxP3)) and patient information. The primary outcome was the mean area under the curve (AUC) of machine learning models in predicting the 1-year PFS.Results We analyzed 100,544 patches of pathological images from 78 patients. …”
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5131
Effects of home-based virtual reality upper extremity rehabilitation in persons with chronic stroke: a randomized controlled trial
Published 2025-02-01“…The outcome measures included the Fugl-Meyer Assessment of upper extremity motor function (FMA-UE), Motor Activity Log-14 (MAL), Jebsen-Taylor Hand Function Test (JTT), and Box and Block Test (BBT) scores. Results All 14 participants completed the study. …”
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5132
Identification and functional characterization of AsWRKY9, a WRKY transcription factor modulating alliin biosynthesis in garlic (Allium sativum L.)
Published 2025-01-01“…Further verification by electrophoretic mobility shift assay (EMSA) and chromatin immunoprecipitation qPCR (ChIP-qPCR) confirmed that AsWRKY9 interacts by binding to the W-box site on the AsFMO1 promoter. Compared to the control, the alliin content in the transgenic callus overexpressing AsWRKY9 was significantly increased, thus confirming the activation of the alliin biosynthesis pathway and enhancing the accumulation of alliin in garlic. …”
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5133
The Effect of Waxing Options on Shelf Life and Postharvest Quality of “ngowe” Mango Fruits under Different Storage Conditions
Published 2019-01-01“…The waxed fruits were then packed in carton boxes and stored either at ambient room temperature (25°C) or cold room (12°C). …”
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5134
Genome-wide identification and expression analysis of phytochrome gene family in Aikang58 wheat (Triticum aestivum L.)
Published 2025-01-01“…The cis-acting element analysis indicates that the promoter regions of TaAkPHY genes contain a large number of CAT-box, CGTCA-motif, GC-motif, etc., which are mainly involved in plant development, hormone response, and stress response. …”
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5135
Τhiazolidine-4-One Derivatives with Variable Modes of Inhibitory Action Against DPP4, a Drug Target with Multiple Activities and Established Role in Diabetes Mellitus Type II
Published 2025-01-01“…Docking analysis was in accordance with the in vitro results, with a linear correlation of logIC<sub>50</sub> with a Probability of Binding Factor(PF) derived using docking analysis to a specific target box and to the whole enzyme. According to the docking results, two probable sites of binding for uncompetitive inhibitors were highlighted in the wider area of the active site and in the propeller loop. …”
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5136
Correlation between immune signature and high‐density lipoprotein cholesterol level in stage II/III colorectal cancer
Published 2019-03-01“…Using immunohistochemistry, tumor tissues were stained with antibodies against CD3, CD8, CD163, iNOS, Forkhead box P3 (FOXP3), and CD33. We calculated the density of positively‐stained infiltrating cells in the tumor center (TC) and invasive margin (IM). …”
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5137
Point-Based Grading System: Advantages and Disadvantages
Published 2021-05-01“…These include: the risk of a biased judgment; fostering individualism when everyone is interested only in his/her personal growth; dominance of the written test over the oral answer; and the use of test tasks, which allows one to determine only the initial conceptual level of the subject without revealing the problematic, conceptual depth of knowledge, without identifying creative minds who can think outside the box. Then, through a mental experiment, various pedagogical situations have been assessed in which a formal use of a point-based grading system leads to biased results. …”
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5138
Nucleotide variation in Foxp3 gene and prognosis of bladder cancer: a case-control study
Published 2025-01-01“…BackgroundNumerous researches have investigated the correlation between single nucleotide polymorphisms (SNPs) in the transcription factor forkhead box protein 3 (Foxp3) gene and the development of various cancers. …”
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5139
Modulation of DAPK1 expression by its alternative splice variant DAPK1-215 in cancer
Published 2025-01-01“…DAPK1-215 promoted migratory and invasive capabilities in liver and kidney cancer cells, but inhibited these processes in gastric cancer cells, without affecting cell proliferation. Mechanistically, DEAD-Box Helicase 3 X-Linked (DDX3X) stabilized both DAPK1-215 and DAPK1 mRNAs, suggesting that DAPK1-215 may act by competing for DDX3X binding to modulate DAPK1 mRNA stability. …”
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5140
Qualitative analysis of patients’ feedback from a PROMs survey of cancer patients in England
Published 2013-04-01“…Of these 1056 (32%) completed the free-text comments box, indicating a high level of commitment to provide written feedback on patient experience. …”
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