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4541
ABA enhances the apoptotic effect of docetaxel in the multidrug-resistant DU145 prostate cancer cell line
Published 2024-01-01“…RT-PCR analysis showed that treatment of resistant cells with 50.07 nM docetaxel and 500 μM ABA (ABA) resulted in the following changes in gene expression: heat shock protein (HSP) 70 (0.63-fold), glucose-regulated protein 94 (GRP94) 0.33-fold, inositol-requiring transmembrane kinase endoribonuclease-1α (IRE1α) 1.62-fold, ER degradation- enhancing alpha-mannosidase-like 1 (EDEM1) 1.77-fold, X-box binding protein 1 (XBP1) 1.53-fold, p21 (2.53-fold), cellular tumor antigen p53 (p53) 2.49-fold, bcl-2-like protein 4 (Bax) 2.7-fold, and tumor necrosis factor (TNF-α) 6.35-fold. …”
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4542
The optimization of calcareous soil cation exchange capacity via the feather hydrolysate and N-P fertilizers integration
Published 2025-02-01“…The main goals of the present study were to generate protein lysate from discarded feathers (enriched in different amino acids) through solid-state fermentation using Box-Behnken design (BBD). Then, assess the efficacy of hydrolyzed feather product (as an organic amendment), time, and N-P fertilizers on soil-CEC planted with maize in calcareous soil utilizing an optimization strategy that employed the central composite design and the response surface methodology (RSM). …”
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4543
Entrepreneurial opportunity decisions under uncertainty: Recognizing the complementing role of personality traits and cognitive skills
Published 2021-01-01“…Practically, our argument provides further insight into the black box of entrepreneurial opportunity decisions under uncertainty and thus highlights the need for a broader perspective for the entrepreneur, especially in the early stage of venture formation, where some cognitions and required personal attributes are needed in consonance for entrepreneurial action. …”
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4544
Assessment of typing methods, virulence genes profile and antimicrobial susceptibility for clinical isolates of Proteus mirabilis
Published 2025-01-01“…Determination of genetic diversity between isolates was performed by different methods (RAPD, ISSR, ERIC, BOX-AIR and REP-PCR) by using several parameters as typeability and discriminatory power indicating that ERIC-PCR was the best method followed by REP-PCR 1R. …”
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4545
Oriented R-CNN With Disentangled Representations for Product Packaging Detection
Published 2024-01-01“…Specifically, we first collect a large number of images of packaged cartons from the real packaging production line and provide detection boxes for them by manual labeling. We have observed that the contextual clues required for different object detection tasks exhibit inconsistency. …”
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4546
Riding Through the Pandemic: Unveiling Motorcycle Crash Trends Amidst Three Years of the COVID-19 Crisis
Published 2025-01-01“…The third wave witnessed a sudden drop, followed by a sharp rise in all three variables. Box and whisker plot analysis confirmed the disparities between observed and predicted values, with observed data being lower. …”
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4547
Evaluation of Biocoagulant “Opuntia ficus-indica and Chitosan” to Improve the Removal of Contaminants in Dairy Effluents through Electrocoagulation
Published 2024-01-01“…Additionally, using the Box–Behnken mathematical model for the removal of TB and COD, the effects and interactions of the factors and experimental design levels (considering control formulations using triplicates) were evaluated. …”
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4548
Vehicle Turn Pattern Counting and Short Term Forecasting Using Deep Learning for Urban Traffic Management System
Published 2025-01-01“…Building on this, we designed a custom vehicle counting algorithm that integrated the BoT-SORT tracker with dynamic counting boxes, accurately capturing vehicle movements and turn patterns in real-time and this integrated approach attained a best deviation of 20.79%. for turn pattern counting and 28.41% for forecasting. …”
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4549
Design and Optimization of a Lightweight and Simple Self-Propelled Crawler Potato Combine Harvester
Published 2024-12-01“…Evaluation indicators such as potato bruise rate, skin breakage rate, loss rate, and impurity content were chosen, and a three-factor, three-level Box–Behnken optimization test was conducted. The results indicated that with a separation screen line speed of 1 m/s, vibration frequency of 8 Hz, and device inclination angle of 30°, the potato damage rate during harvesting was 1.318%, the skin breakage rate was 1.825%, the loss rate was 2.815%, and the impurity rate was 2.736%. …”
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4550
Bioinformatics Analysis of Exercise-Related Biomarkers in Diabetes
Published 2022-01-01“…Afterward, three hub genes (HSPA8, STIP1, and HSPH1) were highly expressed after exercise through the box plot analysis. Conclusion. A myriad of research results confirms that there is a certain connection between exercise and diabetes, which provides a favorable basis for emerging exercise into the treatment of diabetic patients.…”
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4551
Effects of marble waste on shear strength and pullout resistance of sand reinforced with Glass Fiber-Reinforced Polymer (GFRP) bars
Published 2025-07-01“…The methodology involved determining basic geotechnical properties and Optimum Mixing Ratios (OMRs) for MW-sand (MWS) mixtures. A large shear box apparatus (0.6 m x 0.6 m x 0.3 m) was used to evaluate the shear strength of sand and optimum MWS samples, as well as the pullout resistance of 8 mm, 12 mm, 16 mm, 20 mm, and 25 mm Thread-Wrapped (TW) GFRP bars embedded in both sand and MWS samples. …”
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4552
Assessment of Artificial Intelligence Models for Developing Single-Value and Loop Rating Curves
Published 2021-01-01“…Furthermore, EA, the MHBMO algorithm, and artificial intelligence (AI) models (ANN and MGGP) performed satisfactorily in some of the cases, while the idea of combining MGGP with GRG reveals that this hybrid method improved the performance of MGGP in this specific application. Unlike the black box nature of ANN, MGGP offers explicit equations for stream rating curves, which may be counted as one of the advantages of this AI model.…”
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4553
Application of Fractal Analysis in Detecting Trabecular Bone Changes in Periapical Radiograph of Patients with Periodontitis
Published 2021-01-01“…Fractal dimension (FD) values were calculated using the fractal box counting approach. Statistical analysis was performed using the chi-square test, Mann–Whitney test, intraclass correlation coefficient, and ANOVA (α = 0.05). …”
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4554
Low-Frequency rTMS over Contralesional M1 Increases Ipsilesional Cortical Excitability and Motor Function with Decreased Interhemispheric Asymmetry in Subacute Stroke: A Randomized...
Published 2022-01-01“…The MEP (paretic hand) and interhemispheric asymmetry, Fugl-Meyer motor assessment, Action Research Arm Test, and box and block test scores improved more in the experimental group than controls at T1 (p<0.05). …”
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4555
Correlation between vitamin D levels, individual and socio-demographic characteristics and COVID-19 infection and death rates in 20 European countries: A modelling study
Published 2020-12-01“…Data distributions were normalised by the Box and Cox approach and the Minitab routine ‘Best Subsets’ was used to select the best descriptor sets for each quantitative model of cases and deaths. …”
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4556
Assessing the Cognitive Sign Features and Guessability of Laboratory Safety Signs for Pharmacy Students
Published 2024-12-01“…Data were analyzed using descriptive statistics, box plots, and the Spearman correlation test. The significance level was set at 0.05. …”
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4557
Optimization of the Production Parameters of Composites from Sugarcane Bagasse and Iron Salts for Use in Dye Adsorption
Published 2019-01-01“…Aiming to optimize the conditions for obtaining composite adsorbents, the Box-Behnken design (BBD) was used to study the effects of mass sugarcane bagasse/mass iron salt, type of mixture of sugarcane bagasse/iron salt, and temperature on the response to be obtained (adsorption capacity, qe) before the execution of the adsorption tests. …”
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4558
Evaluation of the Inhibitory Effect of Moringa oleifera Leaves Methanolic Extract against In Vitro Growth of Several Babesia Species and Theileria equi and the In Vivo Growth of Ba...
Published 2023-01-01“…MOL’s in vitro antibabesial activity was enhanced when administrated simultaneously with either diminazene aceturate (DA) or MMV665875 compound from malaria box. In mice infected by B. microti, a combination of MOL and a low dose of DA (12.5 mg·kg−1) resulted in a significant (P<0.05) reduction in B. microti growth. …”
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4559
Implementing a rapid geographic range expansion - the role of behavior changes
Published 2023-09-01“…We found that grackles in the edge population had a higher flexibility variance (measured by reversal learning) and a higher persistence average (they participated in a larger proportion of trials), and that there were no population differences in average levels of flexibility, innovativeness (number of loci solved on a multiaccess box), or exploration (latency to approach a novel environment). …”
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4560
Optimizing bioethanol production from sweet sorghum stem juice under very high gravity fermentation and temperature stress conditions
Published 2025-03-01“…Response surface methodology based on a Box-Behnken design was employed to optimize initial sugar (267 g/L), urea (3.24 g/L), and cell concentration (1.32 × 108 cells/mL) for maximization of ethanol concentration (PE), productivity (QP), and sugar consumption (%SC). …”
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