Development and Validation of HPLC Method for the Simultaneous Determination of Five Food Additives and Caffeine in Soft Drinks by Bürge Aşçı, Şule Dinç Zor, Özlem Aksu Dönmez

“…Box-Behnken design was applied to optimize high performance liquid chromatography (HPLC) conditions for the simultaneous determination of potassium sorbate, sodium benzoate, carmoisine, allura red, ponceau 4R, and caffeine in commercial soft drinks. …”
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The Role of Dopamine in Impulsivity and Substance Abuse: A Narrative Review by Connor J Plaisance, Lloyd F Ledet III, Nicholas J Slusher, Charles P Daniel, Zachary Lee, Bradley Dorius, Sonnah Barrie, Tomasina Q Parker-Actlis, Shahab Ahmadzadeh, Sahar Shekoohi, Alan D Kaye

“…Discovery as a key player in the development of addiction dates to the 1950s, with a study performed by Olds and Milner on rats placed in a Skinner box. Their original discovery is part of the beginning of what would become the search into the main mechanistic source of addiction, and how exactly it works at a cellular, physiological, and psychological level. …”
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Optimal Coverage Path Planning for UAV-Assisted Multiple USVs: Map Modeling and Solutions by Shaohua Pan, Xiaosu Xu, Yi Cao, Liang Zhang

“…By refining the axial, length, width, and coordinate information of obstacles, the algorithm enables YOLOv5 to generate accurate object bounding box prompts and then assists SAM in automatically and accurately extracting obstacles and coastlines in complex scenes. …”
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Push-Out Tests on Large Diameter and High Strength Welded Stud Connectors by Fei Yang, Yuqing Liu, Yongjun Li

“…Welded stud connectors, typically 19 mm and 22 mm in diameter, are usually densely arranged at the interface between the steel anchorage box and the wall of the concrete pylon to transfer the huge cable force into the concrete pylon. …”
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Curcumin inhibits growth and triggers apoptosis in human castration-resistant prostate cancer cells via IGF-1/PI3K/Akt pathway by Chao Chen, Qiwu Wang, Jiwen Liu

“…Phosphoinositide 3-kinase (PI3K), Akt, and forkhead box protein O1 (FOXO1) expression and phosphorylation were assessed by western blotting. …”
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An efficient and lightweight detection method for stranded elastic needle defects in complex industrial environments using VEE-YOLO by Qiaoqiao Xiong, Qipeng Chen, Saihong Tang, Yiting Li

“…Finally, EIoU Loss replaced CIoU Loss to address bounding box aspect ratio variability and sample imbalance challenges, significantly improving overall detection task performance. …”
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In house virtual surgery and 3D complex head and neck reconstruction by Kimberly Luu, Amirreza Pakdel, Edward Wang, Eitan Prisman

“…However, third party access to this technology is costly and removes the opportunity to design, create, and modify the bony reconstructions, as third party technology is a black box. This series is a pilot study to document the feasibility of an in-house software tool. …”
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Deep learning modeling of manufacturing and build variations on multistage axial compressors aerodynamics by Giuseppe Bruni, Sepehr Maleki, Senthil K. Krishnababu

“…Compared to traditional “black-box” surrogate models, it provides explainability to the predictions of the overall performance by identifying the corresponding aerodynamic drivers. …”
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Laryngeal cancer diagnosis based on improved YOLOv8 algorithm by Xin Nie, Xueyan Zhang, Di Wang, Yuankun Liu, Lumin Xing, Wenjian Liu

“…The larynx, also known as the voice box, plays a crucial role in voice production and ventilation. …”
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Dual Functions of the C5a Receptor as a Connector for the K562 Erythroblast-Like Cell-THP-1 Macrophage-Like Cell Island and as a Sensor for the Differentiation of the K562 Erythrob... by Hiroshi Nishiura, Rui Zhao, Tetsuro Yamamoto

“…The transcriptional nuclear factor binding to the Y box of human leukocyte antigen genes (NF-Y) for the C5a receptor (C5aR) gene is active in erythroblasts. …”
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Optimization of a fermented pumpkin-based beverage to improve Lactobacillus mali survival and α-glucosidase inhibitory activity: A response surface methodology approach by W.Y. Koh, U. Uthumporn, A. Rosma, A.R. Irfan, Y.H. Park

“…Keywords: Probiotics, Response surface methodology, Box-Behnken, Hyperglycaemia, Functional food…”
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Medium-term load forecasting with Power Market Survey: GEPCO case study by Sheeza Mariam Nawaz, Ubaid Ahmed, Adil Amin, Syed Afraz Hussain Shah, Anzar Mahmood

“…The deep-learning networks (DLNs), proposed in recent years, have a black-box nature, which reduces the interpretability of the results. …”
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OCT-based diagnosis of glaucoma and glaucoma stages using explainable machine learning by Md Mahmudul Hasan, Jack Phu, Henrietta Wang, Arcot Sowmya, Michael Kalloniatis, Erik Meijering

“…However, current automated diagnostic approaches on Glaucoma diagnosis solely rely on black-box deep learning models, lacking explainability and trustworthiness. …”
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Genome Sequencing of a Mung Bean Plant Growth Promoting Strain of P. aeruginosa with Biocontrol Ability by Devaraj Illakkiam, Manoharan Shankar, Paramasivan Ponraj, Jeyaprakash Rajendhran, Paramasamy Gunasekaran

“…In addition, niche-specific genes such as phosphate solubilising 3-phytase, adhesins, pathway-specific transcriptional regulators, a diguanylate cyclase involved in cellulose synthesis, a receptor for ferrienterochelin, a DEAD/DEAH-box helicase involved in stress tolerance, chemotaxis/motility determinants, an HtpX protease, and enzymes involved in the production of a chromanone derivative with potent antifungal activity were identified.…”
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Design and Optimization Application of Cut Blasting Parameters for One-Time Completion of Blind Shaft by Yifeng Zhang, Yongsheng Jia, Nan Jiang, Quanming Xie, Lin Yuan, Yongbo Wu, Zehui Xu

“…Quantitative description of the distribution pattern of blasting-induced cracks in the simulation results of three cutting methods using the box-counting fractal dimension method are presented. …”
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Investigating Low-Frequency Electromagnetic Fluctuations on PCB Surfaces: A Near-Field Analysis of CBCPW Transmission Lines up to 15.2 MHz by Mariusz Zubert, Mariusz Jankowski, Zbigniew Kulesza

“…Advanced statistical methods, including the Hurst exponent and Ljung-Box tests, are integrated with traditional near-field measurements to quantify electromagnetic noise persistence and independence across frequencies. …”
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Anti-HMGB1 Neutralizing Antibody Ameliorates Neutrophilic Airway Inflammation by Suppressing Dendritic Cell-Mediated Th17 Polarization by Fang Zhang, Gang Huang, Bo Hu, Li-Ping Fang, E-Hong Cao, Xiao-Feng Xin, Yong Song, Yi Shi

“…We demonstrate that high mobility group box 1 protein (HMGB1) directs Th17 skewing by regulating dendritic cell (DC) function. …”
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The role of insulin signaling with FOXO and FOXK transcription factors by Masaji Sakaguchi

“…Recent studies demonstrated that two types of forkhead-box family transcription factors, FOXOs and FOXKs, are related to the switching of insulin signals during fasting and feeding states. …”
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Safety-Critical Oracles for Metamorphic Testing of Deep Learning LiDAR Point Cloud Object Detectors by Simon Speth, Maximilian Trien, Dominik Kufer, Alexander Pretschner

“…We address this by introducing novel egocentric test oracles based on traffic participants’ bounding boxes shifted into or out of the ego vehicle’s expected lane. …”
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Ultrasonication-assisted lipase-catalyzed esterification of chlorogenic acid: A comparative study using fatty alcohol and acids in solvent and solvent-free conditions by Chia-Hung Kuo, Parushi Nargotra, Tsung-Han Lin, Chwen-Jen Shieh, Yung-Chuan Liu

“…Catalytic factors such as reaction time (12 h ∼ 36 h), enzyme dosage (10 ∼ 50 mg), and ultrasonication power (90 ∼ 150 W) were optimized using Box-Behnken design (BBD) while temperature (60 ℃) and molar ration (chlorogenic acid/octanol, 1:500) were kept constant. …”
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