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  1. 2601

    PPAR𝜸 and Oxidative Stress: Con(𝜷) Catenating NRF2 and FOXO by Simone Polvani, Mirko Tarocchi, Andrea Galli

    Published 2012-01-01
    “…However, PPARγ does not act alone: indeed the nuclear receptor is at the point of interconnection of various pathways, such as the nuclear factor erythroid 2-related factor 2 (NRF2), Wnt/β-catenin, and forkhead box proteins O (FOXO) pathways. Here we reviewed the role of PPARγ in response to oxidative stress and its interaction with other signaling pathways implicated in this process, an interaction that emerged as a potential new therapeutic target for several oxidative-related diseases.…”
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