Efficacy of Trimebutine Maleate (Trimedat®) in the Treatment of Patients with Functional Dyspepsia: Results of the “TREND” Observational Study by S. S. Kardasheva, I. M. Kartavenko, N. B. Maksimova, E. Yu. Yurieva, I. R. Popova, Ch. S. Pavlov, V. T. Ivashkin

“…The combination of FDS with gastroesophageal reflux disease (GERD) was noted in 15 patients (15 %). Irritable bowel syndrome (IBS) was present in 21 cases (21 %). …”
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Proximal Sessile Serrated Adenomas Are More Prevalent in Caucasians, and Gastroenterologists Are Better Than Nongastroenterologists at Their Detection by Malav P. Parikh, Sujit Muthukuru, Yash Jobanputra, Kushal Naha, Niyati M. Gupta, Vaibhav Wadhwa, Rocio Lopez, Prashanthi N. Thota, Madhusudhan R. Sanaka

“…Detection rates based on patient gender, race, colonoscopy timing, fellow participation, bowel preparation quality, and specialty of the endoscopist were calculated. t-tests were used to compare detection rates and a multivariate-adjusted analysis was performed. …”
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Deficiency of Dietary Fiber in Slc5a8-Null Mice Promotes Bacterial Dysbiosis and Alters Colonic Epithelial Transcriptome towards Proinflammatory Milieu by Sathish Sivaprakasam, Pramodh K. Ganapathy, Mohd Omar Faruk Sikder, Moamen Elmassry, Sabarish Ramachandran, Kameswara Rao Kottapalli, Vadivel Ganapathy

“…Inflammatory bowel disease (IBD) is characterized by chronic inflammation in the intestinal tract due to disruption of the symbiotic relationship between the host immune system and microbiota. …”
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Oral Administration of Lactobacillus plantarum 299v Reduces Cortisol Levels in Human Saliva during Examination Induced Stress: A Randomized, Double-Blind Controlled Trial by Hannah Andersson, Cecilia Tullberg, Siv Ahrné, Kristina Hamberg, Irini Lazou Ahrén, Göran Molin, Mikael Sonesson, Åsa Håkansson

“…A probiotic bacterium with ability to reduce symptoms of irritable bowel syndrome (IBS) prohibited increased levels of the stress marker cortisol during the examination period. …”
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Validation of a Model Estimating the Budget Impact of Video Capsule Endoscopy for Surveillance of Crohn’s Disease in an Italian Center by Rhodri Saunders, Carlo Calabrese, Dania Gelli, Jason Davis, Rafael Torrejon Torres

“…**Conclusions:** Implementing VCE in the surveillance of patients with Crohn’s disease and small bowel involvement may be cost saving in Italy. The congruence between model predictions and real-world patient records supports using this discrete-event simulation to inform healthcare decisions.…”
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Poly-γ-Glutamic Acid Attenuates Angiogenesis and Inflammation in Experimental Colitis by Munkhtugs Davaatseren, Jin-Taek Hwang, Jae Ho Park, Myung-Sunny Kim, Shuaiyu Wang, Mi Jeong Sung

“…Poly-γ-glutamic acid (γ-PGA), naturally secreted from various strains of Bacillus, has anti-inflammatory activity. In inflammatory bowel disease (IBD), inflammation is promoted and sustained by angiogenesis; however, the role played by γ-PGA in this condition is unclear. …”
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EUS-FNA Diagnosis with Core Biopsy of Pancreatic Metastases from Primary Breast Cancer by Samuel Galante Romanini, Juan Pablo Román Serrano, Juliana Silveira Lima de Castro, Isabela Trindade Torres, Alex Ingold, André Lucchiari Borini, Luiz Augusto Sanches Zulske, Maria Bruna Feitosa Matias, Jéssica Said de Marchi, José Andrés Sanchez Pulla, José Celso Ardengh

“…The most commonly reported primary sites for pancreatic metastases are the kidneys, lungs, breast, bowel, and skin (melanoma). Case Summary. The authors report a case of pancreatic metastasis derived from a primary breast cancer that underwent endoscopic ultrasound fine-needle aspiration (EUS-FNA) core biopsy to obtain tissue, which made it possible to perform an immunohistochemical study. …”
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A Rare Case of Colonic Sarcoidosis Presenting as a Mass by Haozhe Sun, Jasbir Makker, Harish Patel, Nikhitha Mantri, Ali N. Hussain, Naeem Abbas

“…Malignancy and inflammatory bowel disease were the initial differentials. A peritoneal biopsy was also performed. …”
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Histopathological assessment of AIDS-defining malignancies in the gastrointestinal tract presenting with acute abdomen: Improving diagnostic timeliness and patient care by M C Khaba, N E Mothata, M O Keetse, T Sumbana

“…Expedited histopathological assessment of bowel resection in HIV-infected patients could improve clinical outcomes with early treatment. …”
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Kiwifruit and Kiwifruit Extracts for Treatment of Constipation: A Systematic Review and Meta-Analysis by Mohamed Eltorki, Russell Leong, Elyanne M. Ratcliffe

“…Standardized mean difference (SMD) and mean difference (MD) with confidence intervals (CI) were determined for the following outcomes: frequency of spontaneous bowel movements (SBM), abdominal pain and straining, as well as stool type as determined by the Bristol Stool Scale (BSS). …”
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Preoperative Nutritional Therapy Reduces the Risk of Anastomotic Leakage in Patients with Crohn’s Disease Requiring Resections by Zhen Guo, Dong Guo, Jianfeng Gong, Weiming Zhu, Lugen Zuo, Jing Sun, Ning Li, Jieshou Li

“…This was a retrospective study. Patients requiring bowel resections due to Crohn’s disease were reviewed. …”
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Meta-Analysis of Expression Profiling Data Indicates Need for Combinatorial Biomarkers in Pediatric Ulcerative Colitis by Xinxiu Li, Eun Jung Lee, Danuta R. Gawel, Sandra Lilja, Samuel Schäfer, Huan Zhang, Mikael Benson

“…However, two had been previously proposed in adult inflammatory bowel diseases (IBD), namely, MMP9 and PROK2. Conclusions. …”
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Delphi study to identify consensus on patient selection for hydrogel rectal spacer use during radiation therapy for prostate cancer in the UK by Amit Bahl, Suneil Jain, Albert Edwards, Rhodri Saunders, Clive Peedell, Heather Ann Payne, James Andrew Thomas, Prantik Das, Amanda Hansson Hedblom, Emily Woodward

“…A higher benefit of spacers can be expected in patients on anticoagulation and in patients with diabetes or inflammatory bowel disease, but consensus could not be reached regarding patient groups expected to benefit less. …”
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Changes in faecal haemoglobin values over sequential rounds of faecal immunochemical tests (FIT) in a surveillance population by Amanda J Cross, Kate Wooldrage, Gemma Mortell, Gwen A Murphy

“…We investigated whether changes in FIT values over multiple rounds were associated with advanced colorectal neoplasia (ACN) detection.Methods A cohort of men and women aged 60–72 years deemed intermediate risk by the 2002 UK adenoma surveillance guidelines and scheduled for three yearly colonoscopies were recruited (January 2012–December 2013) within the English Bowel Cancer Screening Programme and offered a quantitative FIT at 1, 2 and 3 years post-baseline colonoscopy for a prospective analysis within a diagnostic accuracy study. …”
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How Abdominal Irrigation During Cesarean Delivery Affects Gastrointestinal Functions and Short-term Maternal Morbidities: A Randomized Controlled Study by Canan SATIR OZEL, Zelal Rojda GUNGORDU, Nisan Helin DONMEZ, Ergul DEMIRCIVI, Oguz Devrim YARDIMCI, Abdulkadir Turgut

“…Results: Although no significant differences were found between the two groups (p>0.05), the return of bowel functions, i.e., passage of flatus and stool, occurred in a shorter period in the irrigation group (19.53 and 34.63 versus 16.73 and 33.7). …”
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Intestinal Permeability Measured by Urinary Sucrose Excretion Correlates with Serum Zonulin and Faecal Calprotectin Concentrations in UC Patients in Remission by C. A. M. Wegh, N. M. de Roos, R. Hovenier, J. Meijerink, I. Besseling-van der Vaart, S. van Hemert, B. J. M. Witteman

“…Quality of life was scored from 32–224 with the inflammatory bowel disease questionnaire (IBD-Q). Results. This group of UC patients, in clinical remission, did not show increased intestinal permeability at baseline of this study. …”
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Reducing Colorectal Cancer Incidence and Disparities: Performance and Outcomes of a Screening Colonoscopy Program in South Carolina by Sudha Xirasagar, Yi-Jhen Li, James B. Burch, Virginie G. Daguisé, Thomas G. Hurley, James R. Hébert

“…The adenoma detection rate was 27.8% (males 34.6% and females 25.1%), advanced neoplasm rate 7.7% (including 3 cancers), cecum intubation rate 98.9%, inadequate bowel preparation rate 7.9%, and adverse event rate 0.9%. …”
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A Unique Case of Mantle Cell Lymphoma Masquerading as a Cecal Mass by Sarahi Herrera-Gonzalez, Dema Shamoon, Tingliang Shen, Simon Badin, Yatinder Bains

“…Surgical resection is usually limited to patients in which complications are seen such as bleeding, perforation, or bowel obstruction. We present a unique case of a 70-year-old male with nonbilious, nonbloody emesis, and symptomatic anemia who was found to have a cecal mass consistent with MCL.…”
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Abdominal lymphatic malformations in children: case series by Carmine Noviello, Alfonso Papparella, Mirko Bertozzi, Giovanna Riccipetitoni, Ilaria Cascone, Carmine Botta, Giulia Fusi, Veronica Vitali, Mercedes Romano

“…At follow up we observed recurrence in a case that required integrated treatment and bowel occlusion after excision in 1 case. This benign malformations may not cause any symptoms to patient. …”
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Identification of ubiquitination-related key biomarkers and immune infiltration in Crohn’s disease by bioinformatics analysis and machine learning by Wei Chen, Zeyan Xu, Haitao Sun, Wen Feng, Zhenhua Huang

“…Abstract Crohn’s disease (CD) is a chronic inflammatory bowel disease with an unknown etiology. Ubiquitination plays a significant role in the pathogenesis of CD. …”
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