Comment on “Biomarkers as Potential Treatment Targets in Inflammatory Bowel Disease: A Systematic Review” by Nicholas-Paul Delicata, Neville Azzopardi, Pierre Ellul

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Issues of diagnostics and treatment of abdominal pain at irritable bowel syndrome at outpatient stage of the healthcare by Yu. A. Kucheryavy, T. L. Lapina, M. A. Livzan, M. F. Osipenko

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Mendelian randomization analysis reveals causal relationship between tonsillectomy and irritable bowel syndrome by Huaiquan Liu, Shuoshuo Shao, Bo Chen, Shili Yang, Xinyan Zhang

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Lupus-Like Syndrome Caused by 5-Aminosalicylic Acid in Patients with Inflammatory Bowel Disease by Andrew W Kirkpatrick, Arthur A Bookman, Flavio Habal

“…BACKGROUND: Although 5-aminosalicylic acid (5-ASA) preparations used to treat inflammatory bowel disease are reported to have fewer side effects than sulphasalazine, increased clinical use of these compounds has resulted in increased reports of significant side effects.…”
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Mesalazine-Induced Acute Pancreatitis in Inflammatory Bowel Disease Patients: A Systematic Review by Pan J, Li Z, Ye C, Zhang X, Yang Q, Zhang X, Zhou Y, Zhang J

“…Juan Pan,1,* Zuyi Li,1,* Chao Ye,2 Xiaojuan Zhang,1 Qiongliang Yang,1 Xu Zhang,1 Ya Zhou,3 Jianjun Zhang2 1Department of Pharmacy, Liuyang Hospital of Traditional Chinese Medicine, Changsha, Hunan, 410300, People’s Republic of China; 2Department of Pharmacy, Guangdong Provincial second Hospital of Traditional Chinese Medicine (Guangdong Provincial Engineering Technology Research Institute of Traditional Chinese Medicine), Guangzhou, Guangdong, 510095, People’s Republic of China; 3Department of Pharmacy, People’s Hospital of Ningxiang City Affiliated to Hunan University of Chinese Medicine, Changsha, Hunan, 410600, People’s Republic of China*These authors contributed equally to this workCorrespondence: Chao Ye, Department of Pharmacy, Guangdong Provincial second Hospital of Traditional Chinese Medicine (Guangdong Provincial Engineering Technology Research Institute of Traditional Chinese Medicine), No. 60, Hengfu Road, Guangzhou, Guangdong, 510095, People’s Republic of China, Email yechao1234256@163.comObjective: Mesalazine is a widely used medication for treating mild to moderate inflammatory bowel disease (IBD). First identified as a potential cause of acute pancreatitis (AP) in 1989, the link between mesalazine and AP has primarily been established through case reports and a limited number of retrospective studies. …”
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Optimal Timing of Simethicone Supplement for Bowel Preparation: A Prospective Randomized Controlled Trial by Zhen-wen Wu, Sheng-gang Zhan, Mei-feng Yang, Yi-teng Meng, Feng Xiong, Cheng Wei, Ying-xue Li, Ding-guo Zhang, Zheng-lei Xu, Ben-hua Wu, Rui-yue Shi, Jun Yao, Li-sheng Wang, De-feng Li

“…Simethicone (SIM), as an antifoaming agent, has been shown to improve bowel preparation during colonoscopy. However, the optimal timing of SIM addition remained undetermined. …”
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Mesenchymal Stem Cell-derived Exosomes: Novel Therapeutic Approach for Inflammatory Bowel Diseases by Cheng-mei Tian, Mei-feng Yang, Hao-ming Xu, Min-zheng Zhu, Yuan Zhang, Jun Yao, Li-sheng Wang, Yu-jie Liang, De-feng Li

“…The anti-inflammatory and immunomodulatory activities of mesenchymal stem cell (MSC)-derived Exos (MSC-Exos) provide a rationale for novel cell-free therapies for inflammatory bowel disease (IBD). Growing evidence has shown that MSC-Exos can be a potential candidate for treating IBD. …”
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Intestinal inflammation in TNBS sensitized rats as a model of chronic inflammatory bowel disease by N. Selve, T. Wöhrmann

“…The applicability and relevance of this new model are discussed with respect to drug development and basic research of inflammatory bowel diseases.…”
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Intraluminal Meckel’s Duplication Cyst Causing Bowel Obstruction in an Infant: A Role for Laparotomy by Mitchell R. Ladd, Alejandro V. Garcia, Derek B. Allison, Jeffrey R. Lukish

“…This report describes a two-month-old girl who presented with signs and symptoms of a distal small bowel obstruction. She underwent an abdominal ultrasound that revealed a right lower quadrant cystic mass. …”
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Application of Spectral Computed Tomography Single-energy Technique to Small Bowel Crohn’s Disease by Pengfei WU, Chuanbing WANG

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The Utility of Fecal Calprotectin in the Real-World Clinical Care of Patients with Inflammatory Bowel Disease by Esmail Abej, Wael El-Matary, Harminder Singh, Charles N. Bernstein

“…There was no significant difference for FCAL results by outcomes on small bowel evaluation among the 21 persons with small bowel CD. …”
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Therapeutic application and potential mechanism of plant-derived extracellular vesicles in inflammatory bowel disease by Jinling Li, Ting Luo, Dou Wang, Yao Zhao, Yuanxiang Jin, Guiling Yang, Xin Zhang

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Causal relationship between inflammatory bowel disease and sex: a Mendelian randomization study by Kaiwen Wang, Yu Lou, Shunjie Tian, Zhihui Tao, Zhihui Tao

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Predictors of Medication Adherence in Pediatric Inflammatory Bowel Disease Patients at the Stollery Children’s Hospital by L Kitney, JM Turner, D Spady, B Malik, W El-Matary, R Persad, HQ Huynh

“…BACKGROUND: Patients with inflammatory bowel disease (IBD) often do not take their medications as prescribed.…”
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Exploring manual therapy in the management of irritable bowel syndrome in adults: A scoping review by Natalia Płóciennik-Korycka, Sara Maria Pani, Bogumiła Bruc, Paolo Contu, Magdalena Wrzesińska

Subjects: “…Irritable bowel syndrome…”
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Antineoplastic Effects of 5-Aminosalicylates and Potential Cancer Preventive Role in Inflammatory Bowel Disease by Hugh J Freeman

“…Early studies from tertiary referral centers in the United States and Europe showed that patients with long-standing and extensive inflammatory bowel disease (IBD) have an increased risk of colon cancer. …”
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Pathogenic role of intestinal microflora changes in patients with irritable bowel syndrome and treatment options by Ye. A. Poluektova, S. Yu. Kuchumova, O. S. Shifrin, A. A. Sheptulin, V. T. Ivashkin

Subjects: “…irritable bowel syndrome…”
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Novel immune cross-talk between inflammatory bowel disease and IgA nephropathy by Qianqian Yan, Zihao Zhao, Dongwei Liu, Jia Li, Shaokang Pan, Jiayu Duan, Zhangsuo Liu

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Clinical Outcomes of COVID-19 and Impact on Disease Course in Patients with Inflammatory Bowel Disease by Panu Wetwittayakhlang, Farah Albader, Petra A Golovics, Gustavo Drügg Hahn, Talat Bessissow, Alain Bitton, Waqqas Afif, Gary Wild, Peter L Lakatos

“…The impact of COVID-19 has been of great concern in patients with inflammatory bowel disease (IBD) worldwide, including an increased risk of severe outcomes and/or possible flare of IBD. …”
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Topical steroids as alternative to systemic hormonal treatment for inflammatory bowel diseases in pediatric practice by E. N. Fedulova, O. V. Shumilova, O. V. Fedorova, O. A. Tutina, G. V. Medyantseva

“…To share experience of application of topical steroids (Budenofalk®) in children with hormone – dependent inflammatory bowel diseases (IBD) and severe side effects on a background of systemic corticosteroids (CS).Original positions. …”
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