Nanoparticles containing intracellular proteins modulate neutrophil functional and phenotypic heterogeneity by Leonore Raudszus, Farbod Bahreini, Susanne Allan, Kai-Uwe Kalies, Charles C. Caldwell, Kathrin Kalies

“…To find out, we used nanoparticles composed of intracellular proteins (cell-derived nanoparticles, CDNPs) and analyzed their effects on cultured murine bone marrow neutrophils (BMN). We observed that CDNPs activate BMN transiently with an increase in the expression of CD11b without triggering classical effector functions. …”
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Macrophage Activation Syndrome/Secondary Hemophagocytic Lymphohistiocytosis in Adult‐Onset Still's Disease: An Uncommon Initial Presentation in a Young Nepalese Female: A Case Repo... by Kanchan Bishwakarma, Kajal Bishwakarma, Sunil Bogati, Saket Jha

“…MAS was suspected of abnormally high ferritin levels, and a bone marrow aspiration biopsy was done. She was given IV steroids with some improvement. …”
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Novel Strategies for the Improvement of Stem Cells’ Transplantation in Degenerative Retinal Diseases by Simona Delia Nicoară, Sergiu Șușman, Oana Tudoran, Otilia Bărbos, Gabriela Cherecheș, Simion Aștilean, Monica Potara, Olga Sorițău

“…The main sources of SCs for the treatment of retinal diseases are the embryo, the bone marrow, the region of neuronal genesis, and the eye. …”
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Thromboelastography for rapid diagnosis of heparin-like anticoagulant release during anaphylaxis-induced coagulopathy in systemic mastocytosis: a case report by Rajkumar Rajendram, Abdul Hadi Al-Qahtani, Farrukh Sheikh

“…Thromboelastography, a point-of-care viscoelastic monitoring (VEM) test identified the presence of heparin-like anticoagulants within minutes. Bone marrow examination subsequently confirmed isolated mastocytosis. …”
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Adiponectin Deficiency Blunts Hypoxia-Induced Mobilization and Homing of Circulating Angiogenic Cells by Bert R. Everaert, Vincent J. Nijenhuis, Florence C. M. Reith, Vicky Y. Hoymans, Jean-Pierre Timmermans, Christiaan J. Vrints

“…One week after AMI, bone marrow (BM) concentration and mobilization of Sca-1+ and Lin−Sca-1+ progenitor cells (PCs) were markedly attenuated under Adipoq−/− conditions, as assessed by flow cytometry. …”
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Nuclear factor I-C regulates intramembranous bone formation via control of FGF signalling by Jieun Lee, Joo-Cheol Park, Heung‐Joong Kim, Hyun Sook Bae, Dong-Seol Lee

“…In contrast, NFI-C overexpression in human bone marrow stromal cells (hBMSCs) significantly increased the expression of these factors. …”
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Nuclear Factor I-C Regulates Stemness Genes and Proliferation of Stem Cells in Various Mineralized Tissue through Epithelial-Mesenchymal Interactions in Dental Epithelial Stem Cell... by Dong-Seol Lee, Yeo Joon Song, Hye Ri Gug, Ji-Hyun Lee, Hyun Sook Bae, Joo-Cheol Park

“…Here, we demonstrate that Nfic regulates Sox2 and cell proliferation in diverse mineralized tissue stem cells such as dental epithelial stem cells (DESCs), dental pulp stem cells, and bone marrow stem cells, but not in fibroblasts. It was also involved in the expression of pluripotency genes Lin28 and NANOG. …”
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Characterizing temporal and global host innate immune responses against SARS-CoV-1 and -2 infection in pathologically relevant human lung epithelial cells. by Vivian Y Tat, Aleksandra K Drelich, Pinghan Huang, Kamil Khanipov, Jason C Hsu, Steven G Widen, Chien-Te Kent Tseng, George Golovko

“…Based on their profound modulation upon infection by SARS-CoV-1, SARS-CoV-2, and Omicron BA.1, four ISGs, i.e., bone marrow stromal cell antigen 2 (BST2), Z-DNA Binding Protein 1 (ZBP1), C-X-C Motif Chemokine Ligand 11 (CXCL11), and Interferon Induced Transmembrane Protein 1 (IFITM1), were identified as potential drug targets against β-CoVs. …”
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Renal Transplantation in Hepatitis C Positive Patients: A Single Centre Experience by P. R. Shah, A. V. Vanikar, M. R. Gumber, H. V. Patel, V. B. Kute, S. M. Godara, H. L. Trivedi

“…TIP consisted of 1 donor-specific transfusion, peripheral blood stem cell infusion, portal infusion of bone marrow, and target-specific irradiation. Their immunosuppression was cyclosporin, 2 ± 1 mg/kg BW/day + prednisone, 10 mg/day. …”
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TRAIL-Dependent Resolution of Pulmonary Fibrosis by David M. Habiel, Ana Paula Moreira, Ugur B. Ismailoglu, Michael P. Dunleavy, Karen A. Cavassani, Nico van Rooijen, Ana Lucia Coelho, Cory M. Hogaboam

“…Both in vivo and in vitro studies demonstrated that Gr-1+TRAIL+ bone marrow-derived myeloid cells blocked the activation of lung myofibroblasts. …”
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Adjuvant Radiotherapy for Synchronous Bilateral Testicular Seminoma: A Case Report and a Review of the Pertinent Literature by Daniel A. Jones, Elizabeth C. Ester, David Leavitt, Robert Sweet, Badrinath Konety, Gautam Jha, L. Chinsoo Cho

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Usefulness of Low-Dose Splenic Irradiation prior to Reduced-Intensity Conditioning Regimen for Hematopoietic Stem Cell Transplantation in Elderly Patients with Myelofibrosis by Etsuko Matsubara, Jun Yamanouchi, Riko Kitazawa, Taichi Azuma, Hiroshi Fujiwara, Takaaki Hato, Masaki Yasukawa

“…Furthermore, the JAK2 V617F mutation disappeared, and fibrosis in the bone marrow regressed. We suggest that splenic irradiation prior to the RIC regimen for HCT in elderly MF patients with massive splenomegaly is safe. …”
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Common Variable Immunodeficiency Associated with Hepatosplenic T-Cell Lymphoma Mimicking Juvenile Systemic Lupus Erythematosus by A. A. Jesus, C. M. A. Jacob, C. A. Silva, M. Dorna, A. C. Pastorino, M. Carneiro-Sampaio

“…The necropsy showed hepatosplenic T-cell lymphoma with diffuse involvement of bone marrow, spleen, liver, and lungs. The lymphoma cells were positive for CD3 immunostaining and negative for CD20 and lysozyme. …”
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Inflamm-Aging-Related Cytokines of IL-17 and IFN-γ Accelerate Osteoclastogenesis and Periodontal Destruction by Jingyi Tan, Anna Dai, Lai Pan, Lan Zhang, Zhongxiu Wang, Ting Ke, Weilian Sun, Yanmin Wu, Pei-Hui Ding, Lili Chen

“…For receptor activator of nuclear factor-κB ligand- (RANKL-) primed bone marrow macrophages (BMMs), IL-17 and IFN-γ enhanced osteoclastogenesis, with the expression of osteoclastogenic mRNA (TRAP, c-Fos, MMP-9, Ctsk, and NFATc1) and protein (c-Fos and MMP-9) upregulated. …”
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Electrospun Gelatin/β-TCP Composite Nanofibers Enhance Osteogenic Differentiation of BMSCs and In Vivo Bone Formation by Activating Ca2+-Sensing Receptor Signaling by Xuehui Zhang, Song Meng, Ying Huang, Mingming Xu, Ying He, Hong Lin, Jianmin Han, Yuan Chai, Yan Wei, Xuliang Deng

“…However, how these composite nanofibers promote the osteogenic differentiation of bone marrow mesenchymal stem cells (BMSCs) is unknown. …”
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In Vitro Effects of Strontium on Proliferation and Osteoinduction of Human Preadipocytes by V. Nardone, R. Zonefrati, C. Mavilia, C. Romagnoli, S. Ciuffi, S. Fabbri, G. Palmini, G. Galli, A. Tanini, M. L. Brandi

“…In searching for all the optimal sources, adipose tissue-derived mesenchymal stem cells (hADSCs or preadipocytes) are able to differentiate into osteoblasts with analogous characteristics to bone marrow mesenchymal stem cells, producing alkaline phosphatase (ALP), collagen, osteocalcin, and calcified nodules, mainly composed of hydroxyapatite (HA). …”
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Impact of hydroxyurea on clinical and biological parameters of sickle cell anemia in children in Abidjan by MIREILLE YAYO- AYE, Adia Eusèbe Adjambri, Boidy Kouakou, Rebecca N'guessan-Blao, Louis Missa Adjé, Taïratou Kamagaté, Vincent Yapo, Duni Sawadogo

“…Curative treatments such as bone marrow transplantation or gene therapy exist, but are not currently performed in Côte d'Ivoire. …”
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Application of Stem Cell Therapy for ACL Graft Regeneration by Canlong Wang, Yejun Hu, Shichen Zhang, Dengfeng Ruan, Zizhan Huang, Peiwen He, Honglu Cai, Boon Chin Heng, Xiao Chen, Weiliang Shen

“…Among the various different types of stem cells, bone marrow-derived mesenchymal stem cells (BMSCs) have been investigated the most, while ligament stem progenitor cells (LDSCs) have demonstrated the best potential in generating tendon/ligament lineage cells. …”
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The Effect of Culture Techniques of Hypoxic Stem Cell Secretome on The Number of Growth Factor TGF-β, BMP-2, VEGF by Mouli Edward, Ferdiansyah Mahyudin, Dionysius Bramta Putra Manyakori

“…This study aimed to evaluate the differential expression of growth factors in cultured normoxic and hypoxic bone marrow stem cell (BMSCs). Methods: This in vitro laboratory experimental study examined normoxic and hypoxic BMSC cultures. …”
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Pretreatment with G-CSF Could Enhance the Antifibrotic Effect of BM-MSCs on Pulmonary Fibrosis by Feiyan Zhao, Wei Liu, Shaojie Yue, Lei Yang, Qingzhong Hua, Yan Zhou, Haipeng Cheng, Ziqiang Luo, Siyuan Tang

“…Granulocyte colony-stimulating factor (G-CSF) can promote the repair of a variety of damaged tissues, but the underlying mechanisms have not yet been fully elucidated. Bone marrow mesenchymal stem cells (BM-MSCs) play an important role in the repair of damaged tissue. …”
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