Extremely Rare Intraoral Presentation of Localized Amyloidosis by Luka Morelato, Igor Smojver, Sven Seiwerth, Dragana Gabrić

“…Histopathological analysis is the first step for diagnosis, but systemic tests, blood counts, urinalysis, bone marrow biopsy, electrocardiography, and digestive endoscopy are recommended to rule out a systemic disease.…”
Get full text

Clopidogrel-Induced Neutropenia after Coronary Stenting: Is Cilostazol a Good Alternative? by Massimo Montalto, Italo Porto, Antonella Gallo, Claudia Camaioni, Roberta Della Bona, Antonio Grieco, Filippo Crea, Raffaele Landolfi

“…We report a case of clopidogrel-induced bone marrow toxicity manifesting with severe neutropenia in a patient treated with multiple coronary stents and provide suggestions for an alternative treatment.…”
Get full text

Candidates Cell Sources to Regenerate Alveolar Bone from Oral Tissue by Masahiro Nishimura, Kazuma Takase, Fumio Suehiro, Hiroshi Murata

“…The candidate tissues that might have differentiation potential as mesenchymal cells for bone regeneration are alveolar bone chip, bone marrow from alveolar bone, periosteal tissue, and gingival tissue. …”
Get full text

A Rare Case of Suppurative Aspergillosis of the Thyroid by Nikhil Dinaker Thada, Sampath Chandra Prasad, Bhasker Alva, Monika Pokharel, Kishore Chandra Prasad

“…Fungal infections of the thyroid usually occur in immunocompromised patients with hematological malignancies, recipients of bone marrow and solid organ allografts on immunosuppression, and patients with AIDS. …”
Get full text

Imatinib-resistance without BCR/ABL Point Mutation in Chronic Myeloid Leukemia by Aytan Shirinova

“…Chronic myeloid leukemia (CML) is a myeloproliferative bone marrow neoplasm that occurs because of a fusion gene called BCR-ABL1. …”
Get full text

Management of Metachronous Bilateral Testis Cancer in a Patient with Pre-B Cell ALL by Kelly T. Harris, Shakil A. Shaikh, Mark W. Ball, Mohamad E. Allaf, Phillip M. Pierorazio

“…We present a patient with a metachronous, second testicular cancer after being diagnosed with pre-B cell ALL and receiving induction chemotherapy for a bone marrow transplant. We discuss the management of bilateral testis masses in a young patient with a hematologic malignancy as well as the role of immunosuppressive chemotherapy in developing a second cancer. …”
Get full text

Current Perspectives in Mesenchymal Stem Cell Therapies for Osteoarthritis by Baldur Kristjánsson, Sittisak Honsawek

“…Mesenchymal stem cells (MSCs) are multipotent progenitor cells found in various tissues, most commonly bone marrow and adipose tissue. MSCs are capable of differentiating into osteocytes, adipocytes, and chondrocytes. …”
Get full text

Effect of Age and Diabetes on the Response of Mesenchymal Progenitor Cells to Fibrin Matrices by A. Stolzing, H. Colley, A. Scutt

“…MSC are low in number in bone marrow, and therefore in vitro expansion is often necessary. …”
Get full text

The Interaction between Bmal1 and Per2 in Mouse BMSC Osteogenic Differentiation by Haiya Zhuo, Yuhong Wang, Qing Zhao

“…In this study, we inhibited the expression of Bmal1 in bone marrow-derived mesenchymal stem cells (BMSCs) using a lentiviral vector harboring RNAi sequences, which increased the osteogenic differentiation capability of BMSCs. …”
Get full text

Mesenchymal Stem Cells Exhibit Both a Proinflammatory and Anti-Inflammatory Effect on Saccular Aneurysm Formation in a Rabbit Model by Michael B. Avery, Brooke L. Belanger, Amy Bromley, Arindom Sen, Alim P. Mitha

“…In this study, we sought to determine whether allogenic bone marrow-derived MSCs had the ability to prevent aneurysm formation in a known rabbit elastase aneurysm model. …”
Get full text

Contribution of Imaging in Diagnosis of Primitive Cyst Hydatid in Unusual Localization: Pleura—A Report of Two Cases by Fatima Zahra Mrabet, Jihane Achrane, Yassir Sabri, Fatima Ezzahra El Hassani, Sanaa Hammi, Jamal Eddine Bourkadi

“…Cyst hydatid may affect all parts of the human body like the heart, the bone marrow, the eye, the brain, the kidney, and the spermatic cord. …”
Get full text

Mechanism and Treatment Strategy of Osteoporosis after Transplantation by Lei Song, Xu-Biao Xie, Long-Kai Peng, Shao-Jie Yu, Ya-Ting Peng

“…Using the signaling pathway or implantation bone marrow stem cell provides a novel direction for the treatment of OP, especially OP after transplantation. …”
Get full text

Stem Cell Hierarchy and Clonal Evolution in Acute Lymphoblastic Leukemia by Fabian Lang, Bartosch Wojcik, Michael A. Rieger

“…Acute lymphoblastic leukemia (ALL) is a highly malignant cancer of the lymphoid system in the bone marrow with a dismal prognosis after relapse. However, stabile phenotypes and functional data of CSCs in ALL, the so-called leukemia-initiating cells (LICs), are highly controversial and the question remains whether there is evidence for their existence. …”
Get full text

Solitary Plasmacytoma of the Mesentery: A Systematic Clinician’s Diagnosis by Georgia Mitropoulou, Adamantia Zizi-Sermpetzoglou, Hippokrates Moschouris, Athanasios Kountourogiannis, Despoina Myoteri, Dionysios Dellaportas

“…Plasma cell dyscrasias include a variant of proliferative disease, characterized by clonal expansion of bone marrow plasma cells, producing a massive quantity of monoclonal immunoglobulin called paraprotein or M-protein. …”
Get full text

The Role of Methylation in Chronic Lymphocytic Leukemia and Its Prognostic and Therapeutic Impacts in the Disease: A Systematic Review by Sevastianos Chatzidavid, Christina-Nefeli Kontandreopoulou, Nefeli Giannakopoulou, Panagiotis T. Diamantopoulos, Christos Stafylidis, Marie-Christine Kyrtsonis, Maria Dimou, Panayiotis Panayiotidis, Nora-Athina Viniou

Get full text

Persistent Lymphadenopathy due to IgG4-Related Disease by Benjamin Smith, Matthew B. Carroll

“…Symptoms persisted despite conservative treatment and eventually the patient underwent multiple lymph node resections and a bone marrow biopsy before a diagnosis of IgG4-related disease (IgG4-RD) was made. …”
Get full text

Anti-Müllerian Hormone as a Sensitive Marker of Ovarian Function in Young Cancer Survivors by Maryna Krawczuk-Rybak, Elzbieta Leszczynska, Marta Poznanska, Beata Zelazowska-Rutkowska, Jolanta Wysocka

“…The lowest AMH values were noted in patients after bone marrow transplantation (BMT) and those treated for Hodgkin lymphoma (HL). …”
Get full text

A Western Case of Intravascular Large B-Cell Lymphoma as Unusual Cause of Persistent Fever by Pier Paolo Piccaluga, Stefania Paolini, Cristina Campidelli, Nicola Vianelli, Luigi Bolondi

“…Two variants are currently recognized, respectively, occurring in either Western (mainly characterized by neurological symptoms and skin involvement) or Eastern countries (with hemophagocytic syndrome, bone marrow, spleen, and liver involvement). We describe an atypical and unprecedented IVLBCL patient, presenting with pronounced features of Eastern cases as well as skin involvement. …”
Get full text

Aplastic Anemia Treated with Eltrombopag during Pregnancy by Yuri Suminaga, Yoshitsugu Chigusa, Tadakazu Kondo, Haruko Okamoto, Yosuke Kawamura, Mana Taki, Masaki Mandai, Haruta Mogami

“…Aplastic anemia is a rare blood disorder characterized by pancytopenia and hypocellular bone marrow. In patients with aplastic anemia, pancytopenia sometimes worsens during pregnancy, and relapse of aplastic anemia in pregnancy is common. …”
Get full text

Oxidative Stress and Heme Oxygenase-1 Regulated Human Mesenchymal Stem Cells Differentiation by Luca Vanella, Christopher Sanford, Dong Hyun Kim, Nader G. Abraham, Nabil Ebraheim

“…This paper describes the effect of increased expression of HO-1 protein and increased levels of HO activity on differentiation of bone-marrow-derived human MSCs. MSCs are multipotent cells that proliferate and differentiate into many different cell types including adipocytes and osteoblasts. …”
Get full text