Polyclonal Recipient nTregs Are Superior to Donor or Third-Party Tregs in the Induction of Transplantation Tolerance by Nina Pilat, Christoph Klaus, Karin Hock, Ulrike Baranyi, Lukas Unger, Benedikt Mahr, Andreas M. Farkas, Fritz Wrba, Thomas Wekerle

“…Using a costimulation-blockade based bone marrow (BM) transplantation (BMT) model with Treg therapy instead of cytoreductive recipient treatment we aimed to determine the most potent Treg population for clinical translation. …”
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NTRK-rearranged spindle cell tumor with SPECC1L-NTRK3 fusion in the thoracic spine: a case report by Mi Zhou, Huaiyuan Xu, Jianxiong Niu, Qibing Yang, Anqi Wang, Hao Wu, Xiangqin Wang, Meng Yang, Jinxin Hu, Qinglian Tang, Jin Wang

“…Following 1 month of entrectinib treatment, the patient experienced considerable tumor shrinkage and symptomatic improvement. For bone-derived NTRK-rearranged spindle cell sarcomas, entrectinib shows promising therapeutic efficacy and should be considered a preferred treatment option.…”
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Establishing the first ever pediatric procedural sedation clinic in a low-income country: Assessment of the safety and efficacy by Tigist Bacha, Segni Kejela, Scott A. Hagen

“…The most common procedure performed was bone marrow aspiration/biopsy in 384 subjects (80.8%). …”
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Comparison of local minocycline hydrochloride delivery and antimicrobial photodynamic therapy as adjuncts to mechanical debridement for the treatment of peri‑implant mucositis: A r... by Abdulrahman M. AlMubarak

“…Peri-implant modified plaque index (mPI), modified gingival index (mGI) and probing depth (PD) were measured at baseline and at 45 days follow-up. Peri-implant crestal bone levels were measured at baseline. Group comparisons were done using One-way analysis of variance and Bonferroni post-hoc adjustment tests. …”
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Differential Reponses of Hematopoietic Stem and Progenitor Cells to mTOR Inhibition by Aimin Yang, Xia Xiao, Mingfeng Zhao, Amanda C. LaRue, Bradley A. Schulte, Gavin Y. Wang

“…Therefore, targeting of the mTOR pathway is an attractive strategy for cancer treatment and several mTOR inhibitors, including AZD8055 (AZD), a novel dual mTORC1/2 inhibitor, are currently in clinical trials. Although bone marrow (BM) suppression is one of the primary side effects of anticancer drugs, it is not known if pharmacological inhibition of dual mTORC1/2 affects BM hematopoietic stem and progenitor cells (HSPCs) function and plasticity. …”
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Implementation and evaluation of a complex outpatient oral antimicrobial therapy program (COpAT) in Canada by Maggie Wong, Davie Wong

“…The top three sources of infections were bone and joint, intra-abdominal, and skin-and-soft tissue. …”
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Adamantinoma-Like Ewing’s Family Tumor of the Sino Nasal Region: A Case Report and a Brief Review of Literature by Pushpa Mahadevan, Subramaniam Ramkumar, V. P. Gangadharan

“…Ewing's sarcoma family of tumors (EFTs) are malignant mesenchymal tumors with a predilection for bone and soft tissue. They are characterized by their monomorphic small blue round cell morphology. …”
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Can Melatonin Act as an Antioxidant in Hydrogen Peroxide-Induced Oxidative Stress Model in Human Peripheral Blood Mononuclear Cells? by Solaleh Emamgholipour, Arash Hossein-Nezhad, Mohammad Ansari

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Gut Mesenchymal Stromal Cells in Immunity by Valeria Messina, Carla Buccione, Giulia Marotta, Giovanna Ziccheddu, Michele Signore, Gianfranco Mattia, Rossella Puglisi, Benedetto Sacchetti, Livia Biancone, Mauro Valtieri

“…Mesenchymal stromal cells (MSCs), first found in bone marrow (BM), are the structural architects of all organs, participating in most biological functions. …”
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An Unusual Case of Radicular Pain Caused by Bilateral Lumbar Synovial Cyst: A Case Report and Review of the Literature by David Ruiz-Picazo, José Ramírez-Villaescusa, Ana Verdejo-González

“…There are different treatment options that range from conservative management to interventions like image-guided epidural steroid injection or direct cyst puncture and finally to open or endoscopic spinal canal decompression and spinal bone fusion with/without instrumentation. A discussion of current management options for this unusual disease is presented. …”
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Healthcare Delivery among Yoruba Bonesetters in Southwest Nigeria and the Need for Collaboration with Orthodox Orthopedic Healthcare Services: A Mixed Method Study by Soladoye S. Asa, Matthew O. Ilori, Lawrence A. Akinyoola

“…All the orthopedic surgeons surveyed believed that TBS lacked knowledge in the management of bone injuries, apart from setting bones. Other issues considered critical by the doctors in the management of fractures by TBS included lack of training in the biology of bones (86.7%) and inability to refer cases to modern health facilities (73.3%). …”
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Clinical Outcomes of Titanium Zirconium and Titanium Dental Implants under Immediate Functional Loading in Posterior Mandibular Region by Aditi Verma, Kaushal Kishor Agrawal, Pooran Chand, Ramashanker, Shuchi Tripathi, Deeksha Arya

“…Clinical parameters including crestal bone loss (CBL), modified plaque index (MPI), probing depth (PD) and modified sulcular bleeding index (MSBI) were measured at baseline and follow-up visits (4, 8, and 12 months). …”
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Fattening performance, slaughter and carcass characteristics of bafra, akkaraman and bafra × akkaraman f1 lambs at different slaughter weights by Büşra Yaranoğlu, Ceyhan Özbeyaz

“…The pieces were dissected into lean, bone, fat and waste parts.</p> <p><strong>Results: </strong>Akkaraman was found to be the highest daily weight gain (P&lt;0,001) and the lowest feed conversation ratio in slaughtering animals (P&lt;0,05). …”
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Prognostic value of the controlling nutritional status (CONUT) score in patients with diffuse large B-cell lymphoma: a meta-analysis by Jinqiang Zhao, Ying Wu

“…Further, the elevated CONUT score showed a significant correlation with the following clinicopathological factors in DLBCL: Ann Arbor stage III-IV, Eastern Cooperative Oncology Group Performance Status (ECOG PS) of 2–4, presence of extranodal disease, ≥high intermediate National Comprehensive Cancer Network International Prognostic Index (NCCN IPI), presence of B symptoms, elevated lactose dehydrogenase (LDH) levels, and presence of bone marrow infiltration. Conclusions An increased CONUT score was dramatically associated with poor OS and PFS in patients with DLBCL, as well as with clinicopathological characteristics representing DLBCL tumor development.…”
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Differences in Pain Intensity of Tumors Spread to the Anterior versus Anterolateral/Lateral Portions of the Vertebral Body Based on CT Scans by Hui-Ching Hsu, Tzu-Yao Liao, Long-Sun Ro, Yu-Hsiang Juan, Chuang-Chi Liaw

“…Eighty-six patients were enrolled in the study. Bone lesions were mainly osteolytic. Thirty-nine tumors spread to the vertebral body in the anterior direction, and 47 in the anterolateral/lateral direction. …”
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Total Lip Reconstruction with Tendinofasciocutaneous Radial Forearm Flap by Eldad Silberstein, Yuval Krieger, Yaron Shoham, Ofer Arnon, Amiram Sagi, Alexander Bogdanov-Berezovsky

“…In 3 cases chin skin was reconstructed as well and in one case a 5 cm segment of mandible was reconstructed using radius bone. In one case where palmaris longus was missing hemi-flexor carpi radialis tendon was used instead. …”
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PRMT7: A Pivotal Arginine Methyltransferase in Stem Cells and Development by Bingyuan Wang, Mingrui Zhang, Zhiguo Liu, Yulian Mu, Kui Li

“…Deficiency or mutation of PRMT7 causes developmental delay, including defects in skeletal muscle, bone, adipose tissues, neuron, and male reproduction. …”
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Diagnosis and management of superficial arteriovenous malformations: French healthcare network’s recommendations by Olivia Boccara, Didier Salvan, Claude Laurian, Caroline Degrugillier-Chopinet, Nathalie Degardin, Jean-Guillaume Dillinger, Julie Malloizel-Delaunay, Stéphane Mouton, Stéphane Munck, Annabel Maruani, Annouk Bisdorff-Bresson

“…They consist of arteriovenous shunts, without cellular hyperplasia or proliferation, which develop in the surrounding tissues (cutaneous, subcutaneous, muscular, bone). Although benign, they are among the most severe of superficial malformations. …”
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Tumor Sinus Paranasal Dengan Perluasan Intrakranial dan Metastasis ke Paru by Sukri Rahman, M. Abduh Firdaus

“…This is because the anatomy of the sinuses, which is a hidden cavity in the bone, which can not be detected by regular physical examination, tend to be asymptomatic at early stages, and located close anatomic proximity to vital structures. …”
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Paravertebral Well-Differentiated Liposarcoma with Low-Grade Osteosarcomatous Component: Case Report with 11-Year Follow-Up, Radiological, Pathological, and Genetic Data, and Liter... by Nicolas Macagno, Stéphane Fuentes, Gonzague de Pinieux, André Maues de Paula, Sébastien Salas, Jean-Camille Mattéi, Charlotte Dupuis, Romain Appay, Alain Aurias, Henry Dufour, Dominique Figarella-Branger, Corinne Bouvier

“…No connection with the underlying bone was detected on imagery and during surgery. …”
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