The effect of space flight on genes expression in brain by A. S. Tsybko, T. V. Ilchibaeva, N. K. Popova

“…In search of underlying mechanisms, many experimental tools have been developed, ranging from microgravity modeling on Earth to space flight investigations, part of which is to study the expression of genes and proteins. Unlike bone and muscle tissue, molecular changes in nerve cells during spaceflight are practically unexplored. …”
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Pattern of Thyroid Disorders in a Tertiary Care Centre of a High-Altitude Region of Nepal: A hospital-based retrospective study by Tirtha Narayan Sah, Anuraj Anu, Binamra Bista

“…Untreated, these disorders can lead to severe health complications such as heart problems, pregnancy complications, goiter, bone health issues, etc. Jumla, a high-altitude Himalayan region in Nepal, includes iodine-deficient areas, making it prone to thyroid disorders. …”
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Extramedullary Hematopoiesis in Uterine Leiomyoma Associated with Numerous Intravascular Thrombi by Xiaoyan Cui, Deniz Peker, Heather O. Greer, Michael G. Conner, Lea Novak

“…A 29-year-old nulliparous female presented with heavy vaginal bleeding and a hematocrit of 22%. No bone marrow biopsy has been performed. She had a history of uterine leiomyomata and menorrhagia for a year. …”
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Regulatory Role of the RUNX2 Transcription Factor in Lung Cancer Apoptosis by Camila Bernal, Andrea Otalora, Alejandra Cañas, Alfonso Barreto, Karol Prieto, Martin Montecino, Adriana Rojas

“…Current studies have confirmed that RUNX2 is closely related to the proliferation, invasion, and bone metastasis of multiple cancer types, such as osteosarcoma, breast cancer (BC), prostate cancer, gastric cancer, colorectal cancer, and lung cancer. …”
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Differential Proteomic Analysis Predicts Appropriate Applications for the Secretome of Adipose-Derived Mesenchymal Stem/Stromal Cells and Dermal Fibroblasts by Stefania Niada, Chiara Giannasi, Alice Gualerzi, Giuseppe Banfi, Anna Teresa Brini

“…This approach led to the recognition of distinct functions related to the conditioned medium of ASCs and DFs, with the former being involved in the regulation of neuronal death and apoptosis and the latter in bone metabolism and ossification. The proosteogenic effect of DF secretome was validated in vitro on human primary osteoblasts, providing a proof of concept of its osteoinductive potential. …”
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Vacuum Assisted Closure Therapy versus Standard Wound Therapy for Open Musculoskeletal Injuries by Kushagra Sinha, Vijendra D. Chauhan, Rajesh Maheshwari, Neena Chauhan, Manu Rajan, Atul Agrawal

“…A free flap was needed to cover exposed bone and tendon in one case in standard wound therapy group. …”
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Pharmacokinetics of PEGylated Recombinant Human Erythropoietin in Rats by Xiaohan Cao, Zhiyong Chen, Zhuoran Yu, Yonghong Ge, Xianyin Zeng

“…In in vivo half-life time measured after 125I-PEG-rHuEPO administration at the doses of 1, 2, and 3 μg/kg, t1/2α was 1.90, 1.19, and 2.50 hours, respectively, whereas t1/2β was 22.37, 26.21, and 20.92 hours, respectively; at 8, 24, and 48 hours after intramuscular administration, PEG-rHuEPO was distributed to all of the examined tissues, however, with high concentrations of radioactivity, only in plasma, blood, muscle at the administration site, and bone marrow. Following a 2 μg/kg single intramuscular administration, approximately 21% of the radiolabeled dose was recovered after almost seven days of study. …”
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Pediatric trapdoor fracture of the orbital floor with Tear-Drop sign: A case report by Zakariae Hakkou, Zainab El Zouiti, Fahd Elayoubi, Adil Abdenbi Tsen

“…Orbital trapdoor fractures are a unique type of blowout fracture seen predominantly in children due to their elastic bone structure, which predisposes to soft tissue entrapment and symptoms such as diplopia. …”
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Biomarkers of Periodontal Tissue Remodeling during Orthodontic Tooth Movement in Mice and Men: Overview and Clinical Relevance by Fabrizia d'Apuzzo, Salvatore Cappabianca, Domenico Ciavarella, Angela Monsurrò, Armando Silvestrini-Biavati, Letizia Perillo

“…Several possible biomarkers representing biological modifications during specific phenomena as simile-inflammatory process, bone resorption and formation, periodontal ligament changes, and vascular and neural responses are proposed. …”
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Quantitative evidence for dimorphism suggests sexual selection in the maxillary caniniform process of Placerias hesternus. by James L Pinto, Charles R Marshall, Sterling J Nesbitt, Daniel Varajão de Latorre

“…The species has a tusk-like projection on its maxillary bone, known as the caniniform process. This process has been hypothesized to be sexually dimorphic since the 1950s, however this claim has not been thoroughly investigated quantitatively. …”
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Quality of Cattle Meat and Its Compositional Constituents by Umer Seid Geletu, Munera Ahmednur Usmael, Yesihak Yusuf Mummed, Abdulmuen Mohammed Ibrahim

“…A number of structural features of meat as connective tissue, muscle fibers, and tendon that attaches the muscle to the bone are visible in joint meat examined through naked eyes. …”
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Bioabsorbable Suture Anchor Migration to the Acromioclavicular Joint: How Far Can These Implants Go? by Giovanna Medina, Guilherme Garofo, Caio O. D’Elia, Alexandre C. Bitar, Wagner Castropil, Breno Schor

“…Advantages are their absorption over time, minimizing the risk of migration or interference with revision surgery, less artifacts with magnetic resonance imaging, and tendon-to-bone repair strength similar to metallic anchors. …”
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Risk Assessment of BRONJ in Oncologic Patients Treated with Bisphosphonates: Follow-Up to 18 Months by Scilla Sparabombe, Lucia Vitali, Alessandra Nori, Ricarda Sara Berlin, Marta Mazur, Giovanna Orsini, Angelo Putignano

“…Bisphosphonates related osteonecrosis of the jaw (BRONJ) is a pathological condition characterized by bone exposure or latent infection in patients treated with the drug. …”
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Nonsyndromic Bilateral Multiple Impacted Supernumerary Mandibular Third Molars: A Rare and Unusual Case Report by G. Siva Prasad Reddy, G. V. Reddy, I. Venkata Krishna, Shravan Kumar Regonda

“…An impacted tooth is defined as the one which is embedded in the alveolus, so that its eruption is prevented, or the tooth is locked in position by bone or the adjacent teeth. The occurrence of multiple supernumerary teeth in only one patient in the absence of an associated systemic condition or syndrome is considered as a rare phenomenon. …”
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Bilateral Congenital Absence of the Stapes Superstructure in Two Siblings by Jose Ignacio Undabeitia, José Undabeitia, Laura Cianci, Luis Padilla, Eduardo Petreñas, Antonio Municio

“…An exploratory tympanotomy was performed and the absence of the stapes superstructure and an abnormal position of the facial nerve could be observed. A bone anchored hearing aid (BAHA) was implanted in both patients with good results. …”
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Full-Mouth Screw-Retained Implant-Supported Rehabilitation with Multiunit Abutments Using Virtual Guided Surgery and Digital Prosthetics Protocol by Igor Ashurko, Artem Trofimov, Svetlana Tarasenko, Sabina Mekhtieva

“…In addition, it retains a condition of soft and bone tissues around prosthetic construction. The aim of this case is to demonstrate a modern approach in planning and realisation of full-mouth screw-retained dental implant prosthetics. …”
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Exploring vestibular stimulation to reduce the influence of cybersickness on virtual reality experiences by Shamus P. Smith, Eugene Nalivaiko, Sam Owen, Didier Depireux, Mark Flynn

“…A vestibular stimulation device using bone conduction was applied to users experiencing cybersickness induced by a VR roller-coaster in a head-worn display. …”
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MMP-Activated Fluorescence Imaging Detects Early Joint Inflammation in Collagen-Antibody-Induced Arthritis in CC-Chemokine Receptor-2-Null Mice, In-Vivo by Jessica M. Ibarra, Fabio Jimenez, Hernan G. Martinez, Kassandra Clark, Seema S. Ahuja

“…These results were confirmed by the histology of ankle joints, which showed significant inflammation, bone loss, and synovial hyperplasia, compared to control mice at postimmunization day 5. …”
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Clear Cell Carcinoma Arising in Vulvar Endometriosis by Pranom Buppasiri, Pilaiwan Kleebkaow, Chantip Tharanon, Apiwat Aue-aungkul, Chumnan Kietpeerakool

“…The mass seemed to be in continuity with the pubic symphysis that would require pubic bone excision and reconstruction with flap surgery to achieve complete resection. …”
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Evaluation on Genotoxicity and Teratogenicity of Aqueous Extract from Cyclocarya paliurus Leaves by Lihong Deng, Jiandu Lei, Jing He, Jing Liu, Luying Wang, Rui Zhang, Xinhua Liu, Yun Liu

“…In this study, we have conducted the genotoxicity assay (including Ames test, bone marrow polychromatic erythrocyte micronucleus test, and sperm abnormality test in mice) and traditional teratogenicity assay in rats (maternal toxicity, embryo toxicity, and teratogenicity test) to assess the genetic and teratogenic safety of aqueous extracts from C. paliurus leaves. …”
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