Variational graph autoencoder for reconstructed transcriptomic data associated with NLRP3 mediated pyroptosis in periodontitis by Pradeep K. Yadalam, Prabhu Manickam Natarajan, Carlos M. Ardila

“…Abstract The NLRP3 inflammasome, regulated by TLR4, plays a pivotal role in periodontitis by mediating inflammatory cytokine release and bone loss induced by Porphyromonas gingivalis. Periodontal disease creates a hypoxic environment, favoring anaerobic bacteria survival and exacerbating inflammation. …”
Get full text

Peripheral Giant Cell Granuloma Associated with a Dental Implant: A Case Report and Review of the Literature by Amy Louise Brown, Paulo Camargo de Moraes, Marcelo Sperandio, Andresa Borges Soares, Vera Cavalcanti Araújo, Fabrício Passador-Santos

“…Four months later, due to recurrence of the lesion, a deeper and wider excisional biopsy with curettage of the adjacent bone was performed. No evidence of recurrence has been reported after 12 months of follow-up. …”
Get full text

Blocking Interleukin-33 Alleviates the Joint Inflammation and Inhibits the Development of Collagen-Induced Arthritis in Mice by Yan Li, Yeqin Fu, Huan Chen, Xiaojin Liu, Mingcai Li

“…Rheumatoid arthritis (RA) is considered a systemic chronic inflammatory joint disease characterized by chronic synovitis and cartilage and bone destruction. Interleukin-33 (IL-33) is a proinflammatory cytokine which is highly expressed in the synovium of RA patients and the joints of mice with collagen-induced arthritis (CIA) and exacerbates CIA in mice. …”
Get full text

Concise Review: The Regulatory Mechanism of Lysine Acetylation in Mesenchymal Stem Cell Differentiation by Hong Yang, Yuexia Liu, Xuanchen Liu, Huihui Gu, Jing Zhang, Chao Sun

“…Nowadays, the use of MSCs has attracted considerable attention in the global science and technology field, with the self-renewal and multidirectional differentiation potential for diabetes, obesity treatment, bone repair, nerve repair, myocardial repair, and so on. …”
Get full text

Developing a Novel and Convenient Model for Investigating Sweat Gland Morphogenesis from Epidermal Stem Cells by Tian Hu, Yongde Xu, Bin Yao, Xiaobing Fu, Sha Huang

“…Initial experiments revealed that ESCs cocultured with embryonic paw pad (EPP) tissue demonstrated glandular structure and cytokeratin 8 (K8) and cytokeratin 18 (K18) positive, while ESCs cocultured with embryonic dorsal skin demonstrated “sea snail” structure and K8, K18 negative. Moreover, bone morphogenetic protein 4 (BMP4) and epidermal growth factor (EGF) concentrations were detected in the medium of the EPP group. …”
Get full text

Pain Management for Nerve Injury following Dental Implant Surgery at Tokyo Dental College Hospital by Ken-ichi Fukuda, Tatsuya Ichinohe, Yuzuru Kaneko

“…While damage to skin tissue or bone invariably heals over time, damage to nerves does not, indicating the need to avoid such injury while performing implant insertion, for example. …”
Get full text

Intravascular Glomus Tumor of the Forearm Causing Chronic Pain and Focal Tenderness by Sang Ki Lee, Dae Geon Song, Won Sik Choy

“…Extradigital glomus tumors have been reported within the palm, wrist, forearm, foot, bone, stomach, colon, cervix, and mesentery. Glomus tumors can originate from the intraosseous, intramuscular, periosteal, intravascular, and intraneural layers. …”
Get full text

Ineffective Erythropoiesis in β-Thalassemia by Jean-Antoine Ribeil, Jean-Benoit Arlet, Michael Dussiot, Ivan Cruz Moura, Geneviève Courtois, Olivier Hermine

“…In this paper, we will focus on the underlying mechanisms leading to premature death of thalassemic erythroid precursors in the bone marrow.…”
Get full text

Higher Risk Myelodysplastic Syndromes in Patients with Well-Controlled HIV Infection: Clinical Features, Treatment, and Outcome by Bradley T. Williamson, Heather A. Leitch

“…CD4 was 1310 cells/mL and HIV viral load <40 copies/mL. Bone marrow biopsy showed RCMD and karyotype included del(5q) and del(7q); IPSS was intermediate-2 risk. …”
Get full text

Effects of lipoxygenase metabolites of arachidonic acid on the growth of human mononuclear marrow cells and marrow stromal cell cultures by V. Desplat, F. Dupuis, F. Trimoreau, C. Dulery, V. Praloran, Y. Denizot

“…The effects of various lipoxygenase metabolites of arachidonic acid (AA) were investigated on the growth of freshly isolated human bone marrow mononuclear cells and marrow stromal cell cultures. …”
Get full text

Assessing Pubic Symphysis Evolution in Guinea Pigs (Cavia porcellus): Insights From Computer Tomography on Primiparous and Non‐Breeding Females by Sabrina Vieu, Héloïse Hugon, Samuel Boucher, Clément Bercker, Jean‐François Bruyas, Marion Fusellier

“…Measurements included the distance between the acetabula, width and bone density of the pubic symphysis. Serial computed tomography scans were performed on each sow over several months, both before and after parturition. …”
Get full text

Rapidly Growing Chondroid Syringoma of the External Auditory Canal: Report of a Rare Case by Ioannis Vasileiadis, Stylianos Kapetanakis, Aristotelis Petousis, Euthimios Karakostas, Christos Simantirakis

“…It confirmed the presence of a 1.5×0.8 cm T2 high-signal intensity lesion in the superior and posterior wall of EAC without signs of bone erosion. The patient underwent complete resection of the tumor. …”
Get full text

Recent advances in adipose-derived mesenchymal stem cell-derived exosomes for regulating macrophage polarization by Zhewei Dong, Yingli Fu, Zhongming Cai, Hao Dai, Yucang He

“…The anti-inflammatory and immunomodulatory properties of these exosomes provide new perspectives for therapeutic approaches for graft inflammation, bone healing, acute lung injury, kidney stones, myocardial infarction, and diabetes-related diseases. …”
Get full text

Current Uses of Poly(lactic-co-glycolic acid) in the Dental Field: A Comprehensive Review by Maria Justina Roxana Virlan, Daniela Miricescu, Alexandra Totan, Maria Greabu, Cristiana Tanase, Cristina M. Sabliov, Constantin Caruntu, Bogdan Calenic

“…PLGA membranes have been studied with promising results, either alone or combined with other materials in bone healing procedures. PLGA scaffolds have been used to regenerate damaged tissues together with stem cell-based therapy. …”
Get full text

An Immature Type II Dens Invaginatus in a Mandibular Lateral Incisor with Talon’s Cusp: A Clinical Dilemma to Confront by Anshul Gangwar, Deepa Singal, K. Y. Giri, Anshita Agarwal, S. Sruthi Keerthi

“…This case report illustrates grinding of the talons cusp followed by nonsurgical endodontic management of dens invaginatus type II with an immature apex and periapical lesions, in which Mineral Trioxide Aggregate (MTA) shows a complete periapical healing with bone formation at the site of the lesions.…”
Get full text

Endoscopic Type 1 Tympanoplasty: Evaluation of Clinical Success and Hearing Improvement by Aynur ALIYEVA, Ramil HASHIMLI

“…Audiometric data, including pure tone averages (PTA) and air-bone gap (ABG) measurements at four frequencies (500, 1000, 2000, and 4000 Hz), were collected preoperatively and postoperatively. …”
Get full text

Cinacalcet Treatment of Primary Hyperparathyroidism by H. M. Rothe, O. Liangos, P. Biggar, A. Petermann, M. Ketteler

“…PTH levels are lowered, and cognitive parameters improve. While an increase in bone mineral density DEXA scan scores was not demonstrated in cinacalcet trials, the same applies to more than half of patients after parathyroidectomy. …”
Get full text

Long noncoding RNA DHRS4 antisense RNA 1 suppresses osteosarcoma cell proliferation and promotes apoptosis through a competitive endogenous RNA mechanism by Zhouzhou Tang, Zhihao Li, Guofeng Wu, Jianjun Li, Jianye Tan, Lixin Zhu

“…Abstract Osteosarcoma (OS) is the most common primary malignant bone tumor. Recent evidence suggests that the novel long noncoding RNA DHRS4 antisense RNA 1 (DHRS4-AS1) serves an important role in cancer progression and metastasis. …”
Get full text

Severe Hyperphosphatemia in a Patient with Mild Acute Kidney Injury by Phuong Chi Pham, Raghu Konanur Ventakaram, Jimmy Pham, Harpreet Sidhu, Nada Bader, Phuong Mai Pham, Phuong Thu Pham

“…Hyperphosphatemia may arise from various conditions including exogenous ingestion, extracellular shifts due to cell death or alterations in acid-base status, increased bone resorption, hormonal dysregulations leading to reduced renal excretion, reduced kidney function, or faulty measurement techniques. …”
Get full text

Pseudohypoparathyroidism type 1A presenting as short stature and congenital hypothyroidism by Ragini Kondetimmanahalli, Jane Lynch, Gary Francis, Heather Gardner, Radhika Pillai

“…For the primary care provider, simple measures of standing height, sitting height, arm span, weight, body mass index (BMI) and bone age (BA) will lead to the correct diagnosis in most short children. …”
Get full text