Pharmacokinetic, Pharmacogenetic, and Other Factors Influencing CNS Penetration of Antiretrovirals by Jacinta Nwamaka Nwogu, Qing Ma, Chinedum Peace Babalola, Waheed Adeola Adedeji, Gene D. Morse, Babafemi Taiwo

“…Other factors are related to pharmacokinetics and pharmacogenetics of the specific ARV agent or mediated by drug interactions, local inflammation, and blood flow. In this review, we provide an overview of the various factors influencing CNS penetration of ARV drugs with an emphasis on those commonly used in sub-Saharan Africa. …”
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Brain Multimodality Monitoring: A New Tool in Neurocritical Care of Comatose Patients by Nudrat Tasneem, Edgar A. Samaniego, Connie Pieper, Enrique C. Leira, Harold P. Adams, David Hasan, Santiago Ortega-Gutierrez

“…These tools include intracranial pressure (ICP) monitors, transcranial Doppler (TCD), Hemedex™ (thermal diffusion probe used to measure regional cerebral blood flow), microdialysis catheter (used to measure cerebral metabolism), Licox™ (probe used to measure regional brain tissue oxygen tension), and continuous electroencephalography. …”
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The Effectiveness of ROMATIF Therapy (Mirror Therapy and Positive Affirmation) on Strength of Muscle and Self-acceptance in Post Stroke Patients by Putu Sintya Arlinda Arsa, Lie Liana Fuadiati, Desy Rinawaty

“… Introduction: Stroke is a neurological condition in which some brain cells die due to a disruption of cerebral blood flow caused by a blockage or rupture of blood vessels. …”
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Laparoscopic Adnexal Detorsion in a 20-Week Pregnant Patient: A Case Report and Literature Review by Rawad Halimeh, Serge Tomassian, Maria El Hage, Nicole Metri, Marianne Bersaoui, Rafi Daou, Elie Anastasiadis

“…Adnexal torsion occurs when there is a complete turn of the ovary, tube, or both resulting in impaired blood flow to the ovary. The diagnosis of adnexal torsion is sometimes challenging due to the enlarged effect of the uterus, the displacement of abdominal and pelvic structures and the nonspecific symptoms in pregnancy. …”
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Droplet microfluidic screening to engineer angiotensin-converting enzyme 2 (ACE2) catalytic activity by Evelyn F Okal, Philip A. Romero, Pete Heinzelman

“…Abstract Background Angiotensin-Converting Enzyme 2 (ACE2) is a crucial peptidase in human peptide hormone signaling, catalyzing the conversion of Angiotensin-II to Angiotensin-(1–7), which activates the Mas receptor and elicits vasodilation, increased blood flow, reduced inflammation, and decreased pathological tissue remodeling. …”
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A Rare Case of Stroke Secondary to Iron Deficiency Anemia in a Young Female Patient by Kavitha Gopalratnam, Kevin Andrew Woodson, Jigarkumar Rangunwala, Kanaga Sena, Manisha Gupta

“…Ischemic strokes occur when there is a sudden obstruction of an artery supplying blood flow to an area of the brain, leading to a focal neurological deficit. …”
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Numerical Investigation of the Effect of Stenosis Geometry on the Coronary Diagnostic Parameters by Sarfaraz Kamangar, Govindaraju Kalimuthu, Irfan Anjum Badruddin, A. Badarudin, N. J. Salman Ahmed, T. M. Yunus Khan

“…In this study, 3D computational simulation of blood flow in three different geometrical shapes of stenosis (triangular, elliptical, and trapezium) is considered in steady and transient conditions for 70% (moderate), 80% (intermediate), and 90% (severe) area stenosis (AS). …”
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Improving reading competence in aphasia with combined aerobic exercise and phono-motor treatment: Protocol for a randomized controlled trial. by Olga Boukrina, Elizabeth B Madden, Brian M Sandroff, Xiangqin Cui, Abubakar Yamin, Yekyung Kong, William W Graves

“…AET, known for its positive impact on cerebral blood flow (CBF) and oxygenation, is hypothesized to facilitate neuroplasticity when administered before PMT, an intensive therapy aimed at strengthening phonological processing. …”
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Retrobulbar Hemodynamic Effects of Nipradilol in Normal and Normal-Tension Glaucoma Eyes by Mitsushi Fukukita, Masashi Ido, Syunsuke Osawa, Mikio Sasoh, Motoyasu Furuta, Kunio Ito, Masahiko Sugimoto, Yukitaka Uji

“…Short-term observations found that nipradilol increased the ocular blood flow in normal and NTG eyes.…”
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Post-pandemic insights on COVID-19 and premature ovarian insufficiency by Han Yaguang, Dai Yang, Wang Kexin, Zhang Xin, Shao Zishen, Zhu Xiaolin

“…Additionally, alterations in vascular function could impair ovarian blood flow and hormonal imbalances may disrupt normal ovarian function. …”
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A Perfusion MRI Study of Emotional Valence and Arousal in Parkinson’s Disease by Sunsern Limsoontarakul, Meghan C. Campbell, Kevin J. Black

“…Self-rated emotional valence and arousal scores, and regional cerebral blood flow (rCBF) measured by perfusion MRI, were measured 4 or 8 times spanning at least 2 weeks in each of 21 subjects with Parkinson’s disease (PD). …”
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Improving myocardial infarction diagnosis with Siamese network-based ECG analysis. by Vaibhav Gadag, Simrat Singh, Anshul Harish Khatri, Shruti Mishra, Sandeep Kumar Satapathy, Sung-Bae Cho, Abishi Chowdhury, Amrit Pal, Sachi Nandan Mohanty

“…<h4>Background</h4>Heart muscle damage from myocardial infarction (MI) is brought on by insufficient blood flow. The leading cause of death for middle-aged and older people worldwide is myocardial infarction (MI), which is difficult to diagnose because it has no symptoms. …”
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Recanalization Therapies in Acute Ischemic Stroke: Pharmacological Agents, Devices, and Combinations by Vijay K. Sharma, Hock Luen Teoh, Lily Y. H. Wong, Jie Su, Benjamin K. C. Ong, Bernard P. L. Chan

“…However, the short therapeutic window, low rates of recanalization, and only modest benefits with IV-TPA have prompted a quest for alternative approaches to restore blood flow in an occluded artery in acute ischemic stroke. …”
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Functional food products in Japan: A review by Shun Iwatani, Naoyuki Yamamoto

“…Major health claims in the new regulation system are associated with fatigue, eyes, memory, stress, sleep, joints, blood flow, body temperature, muscles, and Body Mass Index. …”
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Transjugular Retrograde Obliteration prior to Liver Resection for Hepatocellular Carcinoma Associated with Hyperammonemia due to Spontaneous Portosystemic Shunt by Fumio Chikamori, Nobutoshi Kuniyoshi

“…Before surgery, transjugular retrograde obliteration (TJO) for the mesocaval shunt was attempted to normalize the portal blood flow. Via the right internal jugular vein, a 6 F occlusive balloon catheter was inserted superselectively into the mesocaval shunt. …”
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Twin Reversed Arterial Perfusion Sequence Diagnosed Late in the Third Trimester: A Case Report and Literature Review by Tafese Dejene, Abdi Kebede, Getahun Fetensa, Delayehu Bekele, Telila Mesfin, Kelil Hussen

“…It is characterized by blood flow from the umbilical artery of the normal (pump) twin to the umbilical artery of the abnormal (acardiac) twin via artery‐to‐artery anastomosis. …”
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Ocular Surface Temperature in Age-Related Macular Degeneration by Andrea Sodi, Sara Matteoli, Giovanni Giacomelli, Lucia Finocchio, Andrea Corvi, Ugo Menchini

“…Considering the possible relationship between ocular blood flow and OST, these findings might support the central role of ischemia in the pathogenesis of AMD.…”
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Concurrence of Crossed Cerebellar Diaschisis and Parakinesia Brachialis Oscitans in a Patient with Hemorrhagic Stroke by Yung-Tsan Wu, Shin-Tsu Chang, Liang-Cheng Chen, Tsung-Ying Li

“…Crossed cerebellar diaschisis (CCD) is defined as a reduction in blood flow in the cerebellar hemisphere contralateral to the supratentorial focal lesion. …”
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Estimation and identification of parameters in a lumpedcerebrovascular model by Scott R. Pope, Laura M. Ellwein, Cheryl L. Zapata, Vera Novak, C. T. Kelley, Mette S. Olufsen

“…The model is combined with experimentalmeasurements of blood flow velocity from the middle cerebral artery andarterial finger blood pressure. …”
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Technique for Measuring the Internal Diameter and Area of Visible Vessels of the Eye by V. A. Firago, A. I. Kubarko

“…The study of the effects on the microvasculature of various vasoactive drugs requires appro-priate methods and equipment for determining the basic physiological parameters of small blood vessels: their internal diameter and cross-sectional area, specific density, and blood flow velocity. Therefore, the purpose of the article is to study the possibilities of improving the reliability of determining the internal diameter and cross-sectional area of the visible blood vessels of bulbar con-junctival of the eye.A technique for obtaining digital video recordings of the bulbar conjunctiva of the eye, based on the pulse illumination of the study area, is proposed. …”
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