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Mechanism of the blood-brain barrier modulation by cadherin peptides
Published 2024-06-01Subjects: Get full text
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The canine blood-brain barrier in health and disease: focus on brain protection
Published 2025-12-01“…This review examines the role of the canine blood-brain barrier (BBB) in health and disease, focusing on the impact of the multidrug resistance (MDR) transporter P-glycoprotein (P-gp) encoded by the ABCB1/MDR1 gene. …”
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Nanotherapeutics for Meningitis: Enhancing Drug Delivery Across the Blood-Brain Barrier
Published 2025-01-01Subjects: Get full text
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Penetration of linezolid and tedizolid in cerebrospinal fluid of mouse and impact of blood–brain barrier disruption
Published 2025-01-01“…The aim of this study is to evaluate the impact of blood brain barrier disruption on CSF penetration of linezolid and tedizolid. …”
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Inhibitory Effect of Matrine on Blood-Brain Barrier Disruption for the Treatment of Experimental Autoimmune Encephalomyelitis
Published 2013-01-01“…Dysfunction of the blood-brain barrier (BBB) is a primary characteristic of experimental autoimmune encephalomyelitis (EAE), an experimental model of multiple sclerosis (MS). …”
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Device-assisted strategies for drug delivery across the blood-brain barrier to treat glioblastoma
Published 2025-01-01“…Abstract The blood-brain barrier, essential for protecting the central nervous system, also restricts drug delivery to this region. …”
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Endothelial-Ercc1 DNA repair deficiency provokes blood-brain barrier dysfunction
Published 2025-01-01“…We here investigated how endothelial aging impacts blood-brain barrier (BBB) function by using excision repair cross complementation group 1 (ERCC1)-deficient human brain ECs and an EC-specific Ercc1 knock out (EC-KO) mouse model. …”
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miRNA in blood-brain barrier repair: role of extracellular vesicles in stroke recovery
Published 2025-02-01Subjects: Get full text
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Triiodothyronine treatment in mice improves stroke outcome and reduces blood–brain barrier damage
Published 2025-02-01Subjects: “…blood–brain barrier…”
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Extracellular Vesicles as Tools for Crossing the Blood–Brain Barrier to Treat Lysosomal Storage Diseases
Published 2025-01-01Subjects: “…blood–brain barrier…”
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Blood-brain barrier breakdown in brain ischemia: Insights from MRI perfusion imaging
Published 2025-01-01“…Ischemic events can cause blood-brain barrier (BBB) disruption and, ultimately, white matter alterations, contributing to neurological deficits and long-term functional impairments. …”
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Ultrasound blood–brain barrier opening: A new era of treatment for Alzheimer's disease?
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Disruption in the Blood-Brain Barrier: The Missing Link between Brain and Body Inflammation in Bipolar Disorder?
Published 2015-01-01“…The blood-brain barrier (BBB) regulates the transport of micro- and macromolecules between the peripheral blood and the central nervous system (CNS) in order to maintain optimal levels of essential nutrients and neurotransmitters in the brain. …”
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The Mast Cell Is an Early Activator of Lipopolysaccharide-Induced Neuroinflammation and Blood-Brain Barrier Dysfunction in the Hippocampus
Published 2020-01-01“…Furthermore, mast cell-deficient KitW-sh/W-sh mice were used to investigate the effects of MCs on microglial and astrocytic activation and blood-brain barrier (BBB) permeability at 4 h after LPS stimulation. …”
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Polystyrene nanoplastics promote the blood-brain barrier dysfunction through autophagy pathway and excessive erythrophagocytosis
Published 2025-01-01Subjects: Get full text
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Iron induces blood-brain barrier alteration contributing to cognitive impairment in β-thalassaemia mice
Published 2025-01-01Subjects: “…Blood-brain barrier…”
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Deoxycholic Acid as a Modifier of the Permeation of Gliclazide through the Blood Brain Barrier of a Rat
Published 2013-01-01“…Gliclazide has antioxidative properties and poor blood brain barrier (BBB) penetration. Bile acids are known for their hypoglycemic effect and as promoters of drug penetration across biological membranes. …”
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Blood-Brain Barrier Abnormalities Caused by HIV-1 gp120: Mechanistic and Therapeutic Implications
Published 2012-01-01“…The blood-brain barrier (BBB) is compromised in many systemic and CNS diseases, including HIV-1 infection of the brain. …”
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Protective Mechanism of Blood-brain Barrier of Cerebral Hemorrhage Model Rats with Different Acupuncture Manipulation Duration
Published 2019-06-01Subjects: Get full text
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BMSCs Regulate Astrocytes through TSG-6 to Protect the Blood-Brain Barrier after Subarachnoid Hemorrhage
Published 2021-01-01“…In patients with subarachnoid hemorrhage (SAH), the damage of the blood-brain barrier (BBB) can be life-threatening. Mesenchymal stem cells are widely used in clinical research due to their pleiotropic properties. …”
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