Application Value of STOP-Bang Questionnaire in Predicting Abnormal Metabolites by Pang Q, Han L, Li J, Xu L, Wang Y

“…A higher SBQ score indicated elevated uric acid (UA), waist circumference (WC), fasting blood glucose (FBG), hemoglobin A1c (HbA1c) and triacylglycerol (TG), but notably lower high density lipoprotein-cholesterol (HDL-C). …”
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Bioinformatics screening and clinical validation of CircRNA and related miRNA in male osteoporosis by Jiayi Li, Sijia Guo, Qingyun Sun, Ning An, Jisheng Lin, Qi Fei

“…Validation experiments were performed on selected circRNAs and related miRNAs in this ceRNA network using peripheral blood clinical samples. Results In total, 657 circRNAs were detected in male osteoporosis. …”
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Efficacy of Photobiomodulation Therapy Utilizing 808 nm and 660 nm Alone and in Combination for Treatment of Paresthesia in Rats by Ehsan Hajesmaelzade, Mohammad Mohammadi, Sina Kakooei, Luca Solimei, Stefano Benedicenti, Nasim Chiniforush

“…The 660 nm, and combined laser groups, had a significantly lower accumulation of inflammatory cells (<i>p</i> < 0.05). The number of blood vessels in combined laser groups was significantly lower than that in the no-laser group (<i>p</i> < 0.05). …”
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Association between intraoperative fluid management and postoperative outcomes in living kidney donors: a retrospective cohort study by Ja Eun Lee, Chisong Chung, Sunghae Park, Kyo Won Lee, Gaab Soo Kim

“…The following covariates were used: age, sex, body weight, height, diabetes mellitus, hypertension, preoperative estimated glomerular filtration rate, operation duration, surgeon, nephrectomy side, and estimated blood loss. Median intraoperative crystalloid infusion rate was 3.5, 4.6, and 6.0 ml/kg/hr in the first, second, and third tertile, respectively (group 1, 2, and 3). …”
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Return to play following craniotomy for non-traumatic brain lesions by Jovanna A. Tracz, Matthew L. Farmer, Mark Hughes, Debraj Mukherjee, Paul M. Brennan

“…The most commonly cited factors influencing RTP decision-making across scenarios were symptomatic recovery (85.4%), resolution of blood and/or air on imaging (43.4%), and patient demand (31.7%). …”
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Tell me y: anticipation of sex discrepancies in cell-free DNA testing due to maternal genetic abnormalities: a case report by Nuria Balaguer, Emilia Mateu-Brull, Jose Antonio Martínez-Conejero, Ana Cervero, Roser Navarro, Jorge Jiménez-Almazán, Miguel Milán

“…Amplification of these regions in the DNA isolated from the white blood cells fraction confirmed the presence of Y-chromosome insertions in the maternal genome. …”
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A Novel Oxidative Stress Mediator in Acute Appendicitis: Thiol/Disulphide Homeostasis by Sefa Ozyazici, Faruk Karateke, Umit Turan, Adnan Kuvvetli, Huseyin Kilavuz, Burak Karakaya, Pınar Ozaltun, Murat Alısık, Ozcan Erel

“…Age, gender, body mass index (BMI), haemoglobin (Hb), white blood cell (WBC), c-reactive protein (CRP), and thiol/disulphide homeostasis parameters (native thiol, total thiol, disulphide, disulphide/native thiol, native thiol/total thiol, and disulphide/total thiol ratios) were compared between the groups. …”
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Assessing the Causal Effect of Circulating Protein‐To‐Protein Ratio on the Risk of Morbidity of Hepatocellular Carcinoma by Qiuyuan Yue, Xiaoxia Li, Xiaoye Wan, Xi Lin, Yueming Li, Mingwei Zhang, Shaohua Xu

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The Association of Polycystic Ovary Syndrome and Gestational Hypertensive Disorders in a Diverse Community-Based Cohort by Diane Schneider, Joel R. Gonzalez, Miya Yamamoto, Jingrong Yang, Joan C. Lo

“…Preexisting hypertension was defined by hypertension diagnosis, treatment, or elevated blood pressure prior to 20 weeks of gestation. The development of PIH, including gestational hypertension, preeclampsia/eclampsia, or HELLP (hemolysis, elevated liver enzymes, and low platelet count), was ascertained by chart review. …”
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The transcription factor HMGB2 indirectly regulates APRIL expression and Gd-IgA1 production in patients with IgA nephropathy by Huijuan Tian, Yaling Zhai, Shuaigang Sun, Wenhui Zhang, Zhanzheng Zhao

“…Our previous study indicated that high migration group protein B2 (HMGB2) in peripheral blood mononuclear cells from patients with IgAN was associated with disease severity, but the underlying mechanism remains unclear.Materials and methods The location of HMGB2 was identified by immunofluorescence. qRT-PCR and Western blotting were used to measure HMGB2, HMGA1, and APRIL expression. …”
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Role of Renal Nerves in the Treatment of Renovascular Hypertensive Rats with L-Arginine by Sonia Alves Gouvea, Renata V. Tiradentes, Cintia H. Santuzzi, Vinícius Mengal, Henrique de A. Futuro Neto, Nyam F. Silva, Gláucia R. Abreu

“…The animals were subdivided into six experimental groups: normotensive control rats (SHAM), 2K1C rats, 2K1C rats treated with L-arginine (2K1C + L-arg), denervated normotensive (DN) rats, denervated 2K1C (2K1C + DN) rats, and denervated 2K1C + L-arg (2K1C + DN + L-arg) rats. Arterial blood pressure, water intake, urine volume, and sodium excretion were measured. …”
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Risk Factor Analysis in Vascular Access Complications for Hemodialysis Patients by Cristian Dan Roşu, Sorin Lucian Bolintineanu, Bogdan Florin Căpăstraru, Roxana Iacob, Emil Robert Stoicescu, Claudia Elena Petrea

“…<b>Conclusions</b>: These findings suggest that clinical interventions, such as stricter perioperative glycemic and blood pressure control, and personalized surgical strategies for patients with high BMI or comorbidities, could significantly reduce the incidence of vascular access complications and improve outcomes in this high-risk population.…”
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Association of Body Fat Percentage with Time in Range Generated by Continuous Glucose Monitoring during Continuous Subcutaneous Insulin Infusion Therapy in Type 2 Diabetes by Yuting Ruan, Jiana Zhong, Rongping Chen, Zhen Zhang, Dixing Liu, Jia Sun, Hong Chen

“…Compared with normal fat T2DM patients, individual with a higher body fat percentage exhibited lower levels of TIR (P=0.004) and higher 72 h mean blood glucose (72 h MBG) (P=0.001) during short-term CSII treatment. …”
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Impact of Different Metabolic Indicators on Ventricular Repolarization Indices in Obese Children: A Case Control Study by Asmaa A El Sehmawy, Rasha Abd El Samad Fawaz, Nadia Ahmed Agiba, Eman Aziz Elsherbiny, Nglaa Fathi Agaba, Doaa Sayed Mohammed, Haidy Mahmoud Nasr, Fatma Elzhraa AE Diab, Amal M Ahmed, Shorouk Issa Mahfouz, Heba T Okda, Doaa Sadek Ahmed

“…A significant positive correlation was detected between QTc and JTc dispersion and the following variables: waist circumference, body mass index (BMI), blood pressure, fasting insulin, HOMA-IR index, and LDL. …”
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Advancing Alzheimer’s disease risk prediction: development and validation of a machine learning-based preclinical screening model in a cross-sectional study by Yanfei Chen, Bing Wang, Yankai Shi, Wenhao Qi, Shihua Cao, Bingsheng Wang, Ruihan Xie, Jiani Yao, Xiajing Lou, Chaoqun Dong, Xiaohong Zhu, Danni He

“…An oversampling method was applied to balance the data set.Interventions This study has no interventions.Participants The study included 2379 participants, of whom 507 were diagnosed with AD.Primary and secondary outcome measures Including accuracy, precision, recall, F1 score, etc.Results 11 variables were critical in the training phase, including educational level, depression, insomnia, age, Body Mass Index (BMI), medication count, gender, stenting, systolic blood pressure (sbp), neurosis and rapid eye movement. …”
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Investigation of Insulin-Like Growth Factor 2 mRNA Binding Protein 2 Gene Polymorphisms in Type 2 Diabetes Patients by Duygu Yolal Ertural, Ümit Çınkır, Nurcan Aras

“…DNA isolation was performed on peripheral blood samples from patients and healthy groups. The molecular analysis of rs1470579 and rs4402960 polymorphisms of IGF2BP2 gene of each individual was performed by using Real-Time PCR (Applied Biosystems) method. …”
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Scalable Manufacturing Method for Model Protein-Loaded PLGA Nanoparticles: Biocompatibility, Trafficking and Release Properties by Selin Akpinar Adscheid, Marta Rojas-Rodríguez, Salma M. Abdel-Hafez, Francesco S. Pavone, Marc Schneider, Akif E. Türeli, Martino Calamai, Nazende Günday-Türeli

“…<b>Background and Objectives</b>: Drug delivery systems (DDSs) offer efficient treatment solutions to challenging diseases such as central nervous system (CNS) diseases by bypassing biological barriers such as the blood–brain barrier (BBB). Among DDSs, polymeric nanoparticles (NPs), particularly poly(lactic-co-glycolic acid) (PLGA) NPs, hold an outstanding position due to their biocompatible and biodegradable qualities. …”
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Mesenchymal Stem Cells from Patients with Rheumatoid Arthritis Display Impaired Function in Inhibiting Th17 Cells by Yue Sun, Wei Deng, Linyu Geng, Lu Zhang, Rui Liu, Weiwei Chen, Genhong Yao, Huayong Zhang, Xuebing Feng, Xiang Gao, Lingyun Sun

“…The effects of RA MSCs on proliferation of peripheral blood mononuclear cells (PBMCs) and distribution of specific CD4+ T cell subtypes (Th17, Treg, and Tfh cells) were investigated. …”
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Evaluation of thiol/disulphide and oxidant–antioxidant status of dairy cows in periparturient and post‐partum period by Burcu Menekse Balkan, Ogunc Meral, Bekir Cetintav, Guzin Ozkurt, Ali Burak Balkan, Tevhide Sel

“…Objectives The purpose of this study is to assess the total antioxidant status (TAS), total oxidant status (TOS), oxidative stress index (OSI), total thiol, native thiol, disulphide and lipid profile in Simmental and Montofon dairy cows (aged 2–3) before and after calving. Methods Blood samples were collected 233–280 days of pregnancy and the 30 days of post‐partum. …”
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Bioactive potential and storage behavior of low molecular mass peptides in Pilsner and IPA style craft beers by Roberta Nogueira Pereira da Silva, Angelica Priscila Parussolo Tonin, Gabriela Soares Macello Ramos, Juliana Furtado Dias, Eduardo Cesar Meurer, Maria Gabriela Bello Koblitz

“…These activities are associated with reduced risk of high blood pressure and metabolic syndrome. After 3 months of storage, peptide intensity decreased in Pilsner samples but increased in IPA samples. …”
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