Amelioration of Coagulation Disorders and Inflammation by Hydrogen-Rich Solution Reduces Intestinal Ischemia/Reperfusion Injury in Rats through NF-κB/NLRP3 Pathway by Ling Yang, Yan Guo, Xin Fan, Ye Chen, Bo Yang, Ke-Xuan Liu, Jun Zhou

“…Additionally, HRS attenuated inflammatory responses and the elevated tissue factor (TF) and inhibited nuclear factor kappa beta (NF-κB) and nucleotide binding and oligomerization domain-like receptor family pyrin domain-containing 3 (NLRP3) inflammasome activation in peripheral blood mononuclear cells. Moreover, inflammatory factors and myeloperoxidase were closely associated with TF level. …”
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Serum vascular endothelial growth factor levels as a marker of skin thickening, digital ischemia, and interstitial lung disease in systemic sclerosis by Chinnadurai Saranya, Ramamoorthy Ramesh, Mahendran Bhuvanesh, Chilukuri Balaji, Selvakumar Balameena, Sankaralingam Rajeswari

“…All patients underwent detailed clinical examination, baseline blood investigations, chest X-ray, electrocardiogram, and pulmonary function tests. …”
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A Child as a Donor for Hematopoietic Stem Cell Transplantation: Bioethical Justification—A Case Study on Sickle Cell Disease by Andrea Z. Pereira, Ricardo Hellman, Nelson Hamerschlak, Andrea Kondo, Polianna Mara Rodrigues de Souza, Wilson Leite Pedreira, Luiz Fernando Alves Lima Mantovani, Eduardo Juan Troster, Henrique Grunspun, Marco Aurélio Scarpinella Bueno

“…The complication for the donor was the need for blood transfusion.…”
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Dichotomitin promotes osteoblast differentiation and improves osteoporosis by inhibiting oxidative stress by Meichun Han, Weibin Du, Lei Zhang, Zhenwei Wang, Shengqiang Fang, Yang Zheng, Renfu Quan

“…Methods SD rats were divided into three groups: Sham, OVX, and OVX + DH (5 mg/kg, intraperitoneal injection twice weekly). After three months, blood samples, femurs, and tibiae were collected for analysis. …”
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Mesenchymal stem cells and their extracellular vesicle therapy for neurological disorders: traumatic brain injury and beyond by Aref Yarahmadi, Masoumeh Dorri Giv, Reza Hosseininejad, Azin Rezaie, Narges Mohammadi, Hamed Afkhami, Hamed Afkhami, Hamed Afkhami, Arastoo Farokhi

“…A comprehensive understanding of vascular components is essential for developing new treatments to improve blood vessel-related brain damage. Recently, mesenchymal stem cells (MSCs) have shown promising results in repairing and mitigating brain damage. …”
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Advancing CNS Therapeutics: Enhancing Neurological Disorders with Nanoparticle-Based Gene and Enzyme Replacement Therapies by Liu S, Li H, Xi S, Zhang Y, Sun T

“…A major obstacle in treating these conditions is the blood-brain barrier (BBB), which restricts the passage of therapeutic agents to the brain. …”
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Bacterial Profile among Patients with Suspected Bloodstream Infections in Ethiopia: A Systematic Review and Meta-Analysis by Birhan Alemnew, Habtamu Biazin, Asmamaw Demis, Melese Abate Reta

“…A total of 26 studies with 8,958 blood specimens and 2,382 culture-positive bacterial isolates were included for systematic review and meta-analysis. …”
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Correlation of Glucose and Lipid Metabolism Levels and Serum Uric Acid Levels with Diabetic Retinopathy in Type 2 Diabetic Mellitus Patients by Tiantian Li, Yan Wu

“…The duration of DM disease, fasting blood glucose (FBG), glycosylated hemoglobin, type A1C (HbA1c) levels, cholesterol (TC), triacylglycerol (TG), low-density lipoprotein cholesterol (LDL-C), and SUA levels were higher in the DR group than those in the NDR group, and the differences were significant (P<0.05). …”
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Frequent Recurrences of Genital Herpes Are Associated with Enhanced Systemic HSV-Specific T Cell Response by Michal Holub, Alžběta Stráníková, Pavel Chalupa, Simona Arientová, Kateřina Roubalová, Ondřej Beran

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A narrative review about cognitive impairment in Metabolic Dysfunction–Associated Steatotic Liver Disease (MASLD): Another matter to face through a holistic approach by Marica Meroni, Miriam Longo, Erika Paolini, Paola Dongiovanni

“…All these conditions contribute to a chronic inflammatory status which may impact on blood brain barrier (BBB) integrity leading to an impaired function of central nervous system (CNS). …”
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Use of Stiripentol in Patients with Dravet Syndrome: Common Practice Among Experts in Spain by Juan José García-Peñas, Rocío Calvo-Medina, Adrián García-Ron, Antonio Gil-Nagel, Vicente Villanueva, Rocío Sánchez-Carpintero

“…In specific cases, stiripentol doses of > 50 mg/kg/day may be contemplated, and acute stiripentol administration may be considered to control refractory status epilepticus. Blood tests should be performed before starting stiripentol, at 3, 6, and 12 months after starting treatment, and then annually, except in the event of adverse effects, when additional testing may be necessary. …”
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Angiotensin II type-1 receptor autoantibodies and effects in neonates of women with preeclampsia by Laure Ponthier, Chahrazed El Hamel, Perrine Coste Mazeau, Sophie Martinez, Sarah Wehbe, Rachel Froget, Catherine Yardin, Vincent Guigonis

“…Methods Women with preeclampsia and their neonates were included. Blood samples were collected in order to search for AT1-AAs. …”
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Binding of CXCL8/IL-8 to Mycobacterium tuberculosis Modulates the Innate Immune Response by Agnieszka Krupa, Marek Fol, Bozena R. Dziadek, Ewa Kepka, Dominika Wojciechowska, Anna Brzostek, Agnieszka Torzewska, Jaroslaw Dziadek, Robert P. Baughman, David Griffith, Anna K. Kurdowska

“…In addition, we have shown that significant amount of IL-8 present in the blood of TB patients associates with erythrocytes. …”
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Occult Hepatitis B Infection among Hemodialysis Patients in Tabriz, Northwest of Iran: Prevalence and Mutations within the S Region by Narges Eslami, Vahdat Poortahmasebi, Javid Sadeghi, Reza Ghotaslou, Bahram Niknafs, Hossein Bannazadeh Baghi, Mahin Ahangar Oskouee

“…HBV serologic screening approaches need to be renewed to cover nucleic acid testing in the setting of hemodialysis and all the other high-risk groups associated with it (i.e., blood and organ donors).…”
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Case Report on Renal Failure Reversal in Lambda Chain Multiple Myeloma with Bortezomib and Dexamethasone by Bhanu K. Patibandla, Akshita Narra, Ahmad A. Alwassia, Anthony Bartley, Gurprataap S. Sandhu, James Rooney, Robert M. Black

“…Labs showed a white cell count—18,900/μL with no bandemia, hemoglobin 10.8 gm/dL, potassium—6.7 mEq/L, bicarbonate—15 mEq/L, blood urea nitrogen—62 mg/dL, SCr—5.6 mg/dL (baseline: 1.10), and corrected calcium—11.8 mg/dL. …”
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Single-Cell RNA Sequencing Analysis of Steroidogenesis and Spermatogenesis Impairment in the Testis of db/db Mice by Yun Hu, Ting-Ting Cai, Reng-Na Yan, Bing-Li Liu, Bo Ding, Jian-Hua Ma

“…The 20-week-old db/db mice had significantly higher blood glucose and body weight (both p<0.001). The serum testosterone levels (4.4 ± 0.8 vs. 9.8 ± 0.7 ng/ml, p=0.001) and weight of the testis (0.16 ± 0.01 vs. 0.24 ± 0.01 g, p<0.001) were significantly lower in db/db mice than that in C57BL/6J controls. db/db mice had a lower cross-sectional area of seminiferous tubules and thickness of the cell layer (both p<0.05). …”
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Modulation of Circulating Cytokine-Chemokine Profile in Patients Affected by Chronic Venous Insufficiency Undergoing Surgical Hemodynamic Correction by Veronica Tisato, Giorgio Zauli, Sergio Gianesini, Erica Menegatti, Laura Brunelli, Roberto Manfredini, Paolo Zamboni, Paola Secchiero

“…In a subgroup of CVI patients, in whom the baseline levels of cytokines/chemokines were analyzed in paired blood samples obtained from varicose vein and forearm vein, EGF, PDGF, and RANTES were increased at the varicose vein site as compared to the general circulation. …”
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In silico methods for immunogenicity risk assessment and human homology screening for therapeutic antibodies by Aimee E. Mattei, Andres H. Gutierrez, Soorya Seshadri, Jacob Tivin, Matt Ardito, Amy S. Rosenberg, William D. Martin, Anne S. De Groot

“…Although this perspective discusses the in-silico immunogenicity risk assessment for monoclonal antibodies, bi-specifics, multi-specifics, and antibody-drug conjugates, the analysis of additional therapeutic modalities such as enzyme replacement proteins, blood factor proteins, CAR-T, gene therapy products, and peptide drugs is also made available on the ISPRI platform.…”
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Correlation Between Serum Uric Acid, Insulin and Hba1c In Type 2 Diabetes Mellitus by Maryam Imtiaz, Samina Saeed, Muhammad Aqeel, Abrar Akbar, Shafaq Saleem, Lubna Meraj

“…A total of 160 adults with diagnosed type II diabetes mellitus were included. Blood reports of patients were analyzed for serum uric acid, HbA1c levels and insulin levels. …”
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Development and validation of highly sensitive multiplex real-time RT-PCR assay for detection of classical swine fever virus genome by A. S. Sadchikova, A. S. Igolkin, R. S. Chernyshev, A. A. Kozlov, I. S. Kolbin, A. V. Sprygin, D. A. Biryuchenkov, I. A. Chvala, A. Mazloum

“…For comparative analysis of the developed as say sensitivity, swabs, samples of organs and tissues collected from pigs experimentally infected with an epizootic strain of the classical swine fever virus (spleen, kidney, liver, blood, lymph nodes, rectal and oral smears), animal-contaminated feed and virus-containing material with known virus titres were also tested in parallel with coded test systems No. x1 andx2. …”
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