Development and Treatments of Inflammatory Cells and Cytokines in Spinal Cord Ischemia-Reperfusion Injury by Ping Zhu, Jia-xin Li, Masayuki Fujino, Jian Zhuang, Xiao-Kang Li

“…During aortic surgery, interruption of spinal cord blood flow might cause spinal cord ischemia-reperfusion injury (IRI). …”
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An Emerging Pulmonary Haemorrhagic Syndrome in Dogs: Similar to the Human Leptospiral Pulmonary Haemorrhagic Syndrome? by R. Klopfleisch, B. Kohn, S. Plog, C. Weingart, K. Nöckler, A. Mayer-Scholl, A. D. Gruber

“…Six dogs had a clinical diagnosis of leptospirosis based on renal and hepatic failure, positive microscopic agglutination test (MAT) and/or positive blood/urine Leptospira-specific PCR. Leptospira could not be cultured post mortem from the lungs or kidneys. …”
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Liver Microbiome in Healthy Rats: The Hidden Inhabitants of Hepatocytes by Xiao Wei Sun, Hua Zhang, Xiao Zhang, Peng Fei Xin, Xue Gao, Hong Rui Li, Cai Yun Zhou, Wen Min Gao, Xuan Xuan Kou, Jian Gang Zhang

“…After the rats were sacrificed by blood drainage from the portal vein, we extracted total deoxyribonucleic acid (DNA) from their ileal and colonic contents and liver tissues. …”
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Characterization of patients with ischemic cerebrovascular disease and cognitive impairment. Cienfuegos, 2018 by Beatriz Perdomo Borges, Teresa Rodríguez Rodríguez, Marianela Fonseca Fernández, Isabel Urquiza Pozo, Idalmis Luisa Martínez Serrano, Belkis Rosa Bilaboy Pérez

“…The risk factors mostly associated with the disease were high blood pressure, diabetes mellitus and smoking. The majority of patients did not suffer depression after cerebral infarction.…”
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Genome Sequencing Reveals the Adaptation of Chickens to High Altitudes in Different Regions by Yizhou Hu, Xing Li, Qixin Guo, Lan Huang, Hao Bai, Guobin Chang

“…Functional annotation of the genes showed that they are primarily involved in energy metabolism, ion channel activity, and blood pressure regulation. Our results provide evidence of genetic diversity among different chicken breeds and reveal the mechanisms of adaptation to high altitudes.…”
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Gene Therapy with Endogenous Inhibitors of Angiogenesis for Neovascular Age-Related Macular Degeneration: Beyond Anti-VEGF Therapy by Selwyn M. Prea, Elsa C. Chan, Gregory J. Dusting, Algis J. Vingrys, Bang V. Bui, Guei-Sheung Liu

“…Current treatments aim to seal off leaky blood vessels via laser therapy or to suppress vessel leakage and neovascular growth through intraocular injections of antibodies that target vascular endothelial growth factor (VEGF). …”
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Glycemic Control in Type 2 Diabetes Mellitus Patients Could Affect NLRP3 Inflammasome Level by Refif Sabih Al-Shawk, Zainab Fadhel Ashoor, Wasan Abdul-elah Bakir, Intisar Manfi Ahmed

“…Also, 30 healthy control subjects were enrolled in this study. HbA1c, fasting blood glucose (FBG), and serum levels of NLRP3 and interferon (IFN)-γ were quantitatively determined by means of a sandwich enzyme-linked immunosorbent assay (ELISA) test. …”
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Evaluation of urinary density as a biomarker for the diagnosis of acute heart failure by Mustafa Ahmet Akçalı, Semih Çınar, Kemal Abid Tekin, Recep Murat Mert, Sena Erduhan, Ertuğ Dinçer, Yusuf Altunöz, Arif Aksu, Esra Akçalı

“…The patient must be evaluated with anamnesis, physical examination, blood, and imaging results to diagnose AHF. Brain natriuretic peptide (BNP) is a widely accepted biomarker for the diagnosis of HF. …”
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Quantification of Metabolic Acidosis at Bedside by S.A.L.T Approach by Harshitha Seshadri, Anitha Nileshwar, Shwethapriya Rao, Nisha Sara M. Jacob

“…Analytical, cross-sectional observational study. Methods: Blood gas reports of 50 adult critically ill patients with primary metabolic acidosis at admission were analyzed using both approaches. …”
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Screening Children with a Family History of Central Congenital Hypoventilation Syndrome by Hina Emanuel, Kimberly Rennie, Kelly Macdonald, Aravind Yadav, Ricardo A. Mosquera

“…All affected individuals had evidence of hypercapnia on blood gas analysis with PCO2 in the range of 32–70 (mean; 61). …”
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Thyrotoxicosis due to Gestational Trophoblastic Disease: Unmet Needs in the Management of Gestational Thyrotoxicosis by Kalyan Mansukhbhai Shekhda, Vladislav Zlatkin, Bernard Khoo, Eleni Armeni

“…In this report, we present two cases (Patient 1: 43 years, Patient 2: 31 years) who came to emergency department following a history of vaginal spotting, palpitations, and hyperemesis. In both patients, blood tests indicated disproportionately elevated β-hCG levels along with high levels of Free T4 (FT4) and Free T3 (FT3), as well as suppressed TSH levels. …”
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GENDER-SPECIFIC INFLUENCE OF Aу MUTATION ON PROGENY METABOLIC PHENOTYPE, FETAL GROWTH AND PLACENTAL GENE EXPRESSION IN MICE by E. N. Makarova, E. I. Denisova, V. V. Kozhevnikova, A. E. Kuleshova

“…In C57Bl mice, the Ау mutation is associated with elevated blood levels of leptin in pregnant females and exerts a gender-specific effect on the metabolic phenotype of mature offspring. …”
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Development and validation of a machine learning-based prediction model for hepatorenal syndrome in liver cirrhosis patients using MIMIC-IV and eICU databases by Fengwei Yao, Ji Luo, Qian Zhou, Luhua Wang, Zhijun He

“…The final predictive model, based on five key variables—spontaneous bacterial peritonitis, red blood cell count, creatinine, activated partial thromboplastin time, and total bilirubin—showed excellent discrimination, with AUCs of 0.832 (95% CI 0.8069–0.8563) in the training set and 0.8415 (95% CI 0.8042–0.8789) in the validation set. …”
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Renal pressure‐flow relationship and renin activation in a porcine model comparing unilateral and bilateral renal artery stenosis by Benny Drieghe, Gunther vanLoon, Sabrina Stuyvaert, Marc L. De Buyzere, Thierry Bové, Tine De Backer

“…Hemodynamic measurements and blood sampling for renin, angiotensin, and aldosterone were performed in baseline conditions and during progressive balloon inflation in the renal artery leading to stepwise 5% Pd decrements. …”
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Effects of age and circadian rhythm on vital parameters and erythrocyte osmotic fragility of donkeys during seasonal changes. by Moses Ayo-Opemipo Olorunfemi, Abdulhakeem Binhambali, Victor Olusegun Sinkalu, Mohammed Babashani, Felix Uchenna Samuel, Joseph Olusegun Ayo

“…Twelve donkeys were classified into three age groups: young (1-3 years), adult (4-6 years), and old (7-9 years). Blood samples were collected at six-hour intervals over a 24-hour period, while dry-bulb and wet-bulb temperatures were measured to compute the temperature-humidity index (THI). …”
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Impact of hypertension on changes in peripapillary retinal nerve fiber layer thickness in type 2 diabetes patients by Jae-Yun Sung, Tae-Seen Kang, Ka-Hyun Lee, Min-Woo Lee

“…In such patients, the duration of ischemic damage caused by HTN appears to have a significant impact on pRNFL damage, and stricter blood glucose level control could help reduce pRNFL damage.…”
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Analysis of periodontal status in Polish patients with rheumatoid arthritis treated with biological therapies by Joanna Samborska-Mazur, Dorota Sikorska, Marzena Liliana Wyganowska

“…The aim of the study was to evaluate the periodontal status in RA patients and its impact on the inflammatory markers and red cell parameters obtained from complete blood laboratory tests to study the risk of cardiovascular disease development. …”
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Development and Validation of the RCOS Prognostic Index: A Bedside Multivariable Logistic Regression Model to Predict Hypoxaemia or Death in Patients with SARS-CoV-2 Infection by Gerardo Alvarez-Uria, Sumanth Gandra, Venkata R. Gurram, Raghu P. Reddy, Manoranjan Midde, Praveen Kumar, Ketty E Arce

“…The final model included 12 variables: age, systolic blood pressure, heart rate, respiratory rate, aspartate transaminase, lactate dehydrogenase, urea, C-reactive protein, sodium, lymphocyte count, neutrophil count, and neutrophil/lymphocyte ratio. …”
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Association of CYP2C9∗3 and CYP2C8∗3 Non-Functional Alleles with Ibuprofen-Induced Upper Gastrointestinal Toxicity in a Saudi Patient by Amina M. Bagher

“…The patient received intravenous proton pump inhibitors and a packed red blood cell transfusion. Genetic analysis revealed that the patient was a carrier of CYP2C9∗3 and CYP2C8∗3 variant alleles, indicating that the patient is a poor metabolizer for both enzymes. …”
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Quantitative analysis of choroidal vascular structures and anatomical changes in pachychoroid spectrum diseases using ultra-widefield SS-OCTA by Bei Xiao, Yanping Song, Ming Yan, Ya Ye, Zhen Huang

“…Abstract This study used ultra-widefield swept-source optical coherence tomography angiography (UWF SS-OCTA) to analyze and compare choroidal blood flow and anatomical changes in eyes affected by central serous chorioretinopathy (CSC), pachychoroid neovasculopathy (PNV), and uncomplicated pachychoroid (UCP). …”
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