A novel irrigation device with superior nasal irrigation efficiency to the classic rinse bottle by Dawei Wu, Feifan Chang, Junsheng Hong, Baihan Su, Yongxiang Wei

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Early and midterm results of Cook Formula stent in children with right heart disease: A single-center experience by Haritha Girija, Chinnasamy Sivaprakasam Muthukumaran, Rajaguru Ganesan, Sankarakuttalan Ramkishore, Vijay Arun, Vellusamy Mahitha, Neville Solomon, Swaminathan Vaidyanathan

“…Background: Branch pulmonary artery (PA) stenosis must be addressed early to prevent right ventricular scarring and establish lung blood flow. Balloon-mounted stents are more useful in managing right ventricular outflow tract (RVOT) obstruction and PA stenosis. …”
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Five-year retrospective analysis of Bakri balloon tamponade for obstetric haemorrhage and patient survey at a single tertiary centre by Tithi Kulkarni, Ruth McCuaig, Gargeswari Sunanda

“…The success group demonstrated significant reductions in median blood loss (1.8 L vs. 2.5 L, p = 0.016) and difference in median duration of BBT (18.3 vs. 3.92 hours, p = 0.001). …”
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Maternal Fructose Intake Induces Insulin Resistance and Oxidative Stress in Male, but Not Female, Offspring by Lourdes Rodríguez, Paola Otero, María I. Panadero, Silvia Rodrigo, Juan J. Álvarez-Millán, Carlos Bocos

“…Therefore, we have investigated whether maternal fructose intake produces subsequent changes in their progeny. Methods. Blood samples from fed and 24 h fasted female and male 90-day-old rats born from fructose-fed, glucose-fed, or control mothers were used. …”
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An appropriate DNA input for bisulfite conversion reveals LINE-1 and Alu hypermethylation in tissues and circulating cell-free DNA from cancers. by Trang Thi Quynh Tran, Tung The Pham, Than Thi Nguyen, Trang Hien Do, Phuong Thi Thu Luu, Uyen Quynh Nguyen, Linh Dieu Vuong, Quang Ngoc Nguyen, Son Van Ho, Hang Viet Dao, Tong Van Hoang, Lan Thi Thuong Vo

“…Using the minuscule DNA amount of 0.5 ng, much less than what has been used and recommended so far (500 ng-2 μg) or 1 μL of cfDNA extracted from 1 mL of blood, we revealed hypermethylation of LINE-1 and Alu in 407 tumour samples of primary breast, colon and lung cancers when compared with the corresponding pair-matched adjacent normal tissue samples (P < 0.05-0.001), and in cfDNA from 296 samples of lung cancers as compared with 477 samples from healthy controls (P < 0.0001). …”
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Robotic-assisted costectomy using a Gigli saw for fibrous dysplasia by Chen Yang, Lei Chen, Hui Wang, Qianyun Wang

“…Median operative time was 76.8 min (range, 73–116 min), and the median intraoperative blood loss volumes was 75 ml (range, 40– 105 mL). …”
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Surgical site infections prevalence among caesarean section patients by Tasneem Alkout, Abdulhamid M. Alkout, Esraa Rasheed, Osama Etekbali, Fathi Abousnina, Alhadi Araibi

“…Material and methods: Samples were collected from patients who had developed wound infection following cesarean section and cultured on blood, chocolate and chromatic agar. The isolated bacteria was identified by ordinary microbiology techniques. …”
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Hepatosplenic Abscesses and Osteomyelitis of the Spine in an Immunocompetent Adult with Cat Scratch Disease by D. Knafl, F. Lötsch, H. Burgmann, G. Goliasch, W. Poeppl, M. Ramharter, F. Thalhammer, C. Schuster

“…All specific laboratory investigations for identification of a specific etiology, including blood cultures and autoantibodies, were inconspicuous. …”
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Safety, Tolerability, and Pharmacokinetics of NIM‐1324 an Oral LANCL2 Agonist in a Randomized, Double‐Blind, Placebo‐Controlled Phase I Clinical Trial by Andrew Leber, Raquel Hontecillas, Nuria Tubau‐Juni, Josep Bassaganya‐Riera

“…At 250 mg, NIM‐1324 successfully engaged the target with an upregulation of Lancl2 and key transcriptional biomarkers in whole blood. In conclusion, NIM‐1324 treatment is well‐tolerated up to daily oral doses of at least 1500 mg (nominal), a ≥ six‐fold margin over the anticipated therapeutic dose, and 1000 mg (maximum observed exposure), at least a four‐fold margin over the anticipated therapeutic dose with no dose limiting toxicities.…”
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Determining Risk Factors of Bleeding in Patients on Warfarin Treatment by Evren Uygungül, Cuneyt Ayrik, Huseyin Narci, Semra Erdoğan, İbrahim Toker, Filiz Demir, Ulas Karaaslan

“…Demographic data, frequency of international normalized ratio (INR) checks, and routine blood results were extracted. Logistic regression analysis was used to determine which factors were most closely associated with bleeding complications. …”
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Identification of Potential Biomarkers for Coronary Artery Disease Based on Cuproptosis by Bohong Zhang, Mingliang He

“…To screen marker genes for CAD from CRGs, we downloaded the whole blood cell gene expression profile of CAD patients and normal samples, i.e., the GSE20680 dataset, from the GEO database. …”
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Positive association between the proinsulin-to-C-peptide ratio and prolonged hyperglycemic time in type 2 diabetes by Aika Miya, Akinobu Nakamura, Hiroshi Nomoto, Hiraku Kameda, Tatsuya Atsumi

“…Continuous glucose monitoring was performed and fasting blood samples were collected and analyzed. We identified the clinical factors associated with the PI:C ratio by multiple regression analysis. …”
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Interaction of milrinone with extracorporeal life support by Whelan Aviva J., Mim Sabiha, Hunt J. Porter, McKnite Autumn M., Green Danielle J., Imburgia Carina E., Momper Jeremiah D., Stitt Gideon, Watt Kevin M.

“…Methods: Ex vivo ECMO and CRRT circuits were primed with human blood and then dosed with milrinone to study drug extraction by the circuits. …”
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Liquefied Petroleum Gas Poisoning in a Child: A Case Report from a Low-Middle Income Country by Abid Jamali, Latif Shamasuddin, Aimen Yunus, Nadeem Ullah Khan

“…However, troponin-I levels were elevated at 135 ng/L (normal range: 0-57 ng/L), and blood gases revealed mild acidosis with bicarbonate levels of 16.8. …”
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The rise of congenital syphilis in Canada: threats and opportunities by Ashorkor Tetteh, Victoria Moore

“…Key recommendations for maximizing impact in curbing infectious and congenital syphilis rates include the following: planning an integrated strategy for addressing sexually transmitted and blood-borne infections as a whole; adopting a more holistic approach to improving health and wellbeing; developing targeted interventions for addressing structural and social barriers to health equity; and taking a collaborative approach to response by involving multilevel stakeholders, such as key populations, community groups, health care providers, and public health authorities.…”
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Neutrophil-to-lymphocyte ratio as a predictor for early mortality in older patients requiring hemodialysis; insights for hemodialysis access planning by Hyo Kee Kim, Heungman Jun, Sun-Young Ko

“…Only patients undergoing blood tests on the day before surgery were included in the analysis. …”
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Sleep behaviour and cardiorespiratory fitness in patients after percutaneous coronary intervention during cardiac rehabilitation: protocol for a longitudinal study by Jie Zhou, Jing Wu, Lan Huang, Yiyan Wang, Husheng Li, Xubo Wu

“…Data collection will include demographic characteristics, medical history, physical examination, blood sampling, echocardiography and the results of cardiopulmonary exercise tests. …”
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The Serum Biomarkers in Ulcerative Colitis by Semih SEZER, Selim DEMIRCI, Melisa Irem KARA, Murat KORKMAZ

“…Objective: In this study, the aim was to evaluate the diagnostic effectiveness of more easily applicable and cost-effective serum biomarkers, such as neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), C-reactive protein (CRP) to albumin ratio (CAR), and CRP-to-lymphocyte ratio (CLR), instead of the endoscopic activity index (EAI) used to determine disease activation in ulcerative colitis (UC) patients. Methods: Blood tests performed during the same period as colonoscopy were reviewed, and NLR, PLR, CAR, and CLR values were calculated. …”
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Diagnosis of COVID-19 Using a Deep Learning Model in Various Radiology Domains by Yousef Alhwaiti, Muhammad Hameed Siddiqi, Madallah Alruwaili, Ibrahim Alrashdi, Saad Alanazi, Muhammad Hasan Jamal

“…Moreover, every country has limited testing capacity; therefore, a system is required which helps the doctor to directly check and analyze the patients’ blood structure. This study proposes a generalized adaptive deep learning model that helps the front-line paramedical employees to easily detect COVID-19 in different radiology domains. …”
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Prevalence and Risk Factors of HIV Infection among Clients Attending ICTCs in Six Districts of Tamilnadu, South India by Rajeswari Ramachandran, V. Chandrasekaran, M. Muniyandi, K. Jaggarajamma, Anasua Bagchi, Supriya Sahu

“…Median age of clients was 30 years; 89% had never used condoms in their lives and 2% gave history of having received blood transfusion. In multivariate analysis HIV seropositivity was associated with HIV in the family (adjusted odds ratio) (AOR 11.6), history of having sex with sex workers (AOR 2.9), age ≥31 years (AOR 2.8); being married (AOR 2.5), previously tested for HIV (AOR 1.9), illiteracy (AOR 1.7), unemployment (AOR 1.5), and alcoholism (AOR 1.5). …”
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