Cytokine Profile of Patients with Allergic Rhinitis Caused by Pollen, Mite, and Microbial Allergen Sensitization by Yury A. Tyurin, Svetlana A. Lissovskaya, Rustem S. Fassahov, Ilshat G. Mustafin, Anton F. Shamsutdinov, Marina A. Shilova, Albert A. Rizvanov

“…The cytokine profile of nasal secretion and blood serum of 44 patients with AR was studied. 24 of them had seasonal allergic rhinitis (SAR), and 20 patients suffered from perennial allergic rhinitis (PAR). …”
Get full text

Peer support and social networking interventions in diabetes self-management in Kenya and Uganda: A scoping review. by Habil Otanga, Brian Semujju, Lynn Mwaniki, Justus Aungo

“…Most interventions were effective and led to improvements in HbA1c and blood pressure, eating behaviors and physical activity and social support.…”
Get full text

LIVER DISEASE & SICKLE CELL DISEASE: AUTOIMMUNE HEPATITIS MORE THAN A COINCIDENCE; A SYSTEMATIC LITERATURE REVIEW. by Kelvin Lynch, Andrea Mega, Andrea Piccin, Massimo Daves, Helen Fogarty

Get full text

A comprehensive review of microplastic pollution in freshwater and marine environments by Irene Monica Jaikumar, Majesh Tomson, Arun Meyyazhagan, Balasubramanian Balamuralikrishnan, Rathinasamy Baskaran, Manikantan Pappuswamy, Hesam Kamyab, Elham Khalili, Mohammad Farajnezhad

“…They have also been found to be present in human blood, multiple organs, and even breast milk. There is an abundance of microplastics in the air we breathe, the food we eat, and the water we drink. …”
Get full text

Utilizing the subtractive proteomics approach to design ensemble vaccine against Candida lusitaniae for immune response stimulation; a bioinformatics study. by Habiba Naz, Rimsha Timotheous, Muhammad Farhan Sarwar, Tariq Nadeem, Mudassar Fareed Awan, Sajed Ali, Sophia Awais, Irfan Ahmed

“…Candida lusitaniae is also one of those fungi which is responsible for different infections in human beings including vaginitis, endocarditis, endophthalmitis and blood stream infections. There is thus, a need to adopt effective therapeutic strategies to tackle such infections. …”
Get full text

Inhibition of Epithelial CC-Family Chemokine Synthesis by the Synthetic Chalcone DMPF-1 via Disruption of NF-κB Nuclear Translocation and Suppression of Experimental Asthma in Mice... by Revathee Rajajendram, Chau Ling Tham, Mohamad Nadeem Akhtar, Mohd Roslan Sulaiman, Daud Ahmad Israf

“…Furthermore, DMPF-1 treatment inhibited eosinophilia, goblet cell hyperplasia, peripheral blood total IgE, and airway hyperresponsiveness in ovalbumin-sensitized and ovalbumin-challenged mice. …”
Get full text

Gypenoside ameliorates insulin resistance and hyperglycemia via the AMPK-mediated signaling pathways in the liver of type 2 diabetes mellitus mice by Mengxue Song, Dehong Tan, Bin Li, Yanqun Wang, Lin Shi

“…The effects of two Gps (Gp-I and Gp-II) on type 2 diabetic mellitus (T2DM) mice, induced by high-fat and high-sugar diet and streptozotocin, were evaluated to explore the mechanism of their hypoglycemic actions. Gps reduced fasting blood glucose and serum lipids, as well as significantly improved T2DM mice glucose tolerance and insulin resistance (IR). …”
Get full text

A review on intrathecal administration of medications for leptomeningeal metastases in solid tumors by Xuemei Wang, Chi Yao, Li Quan, Junxiang Zhou

“…This therapy can directly circumvent the blood–brain barrier. Moreover, a low-dose medication can achieve a higher drug concentration in the CSF, resulting in better cytotoxic effects. …”
Get full text

Variability of anti-Müllerian hormone and folliculotropic hormone levels in women of reproductive age in relation to normal or impaired ovarian function by Małgorzata Jusiakowska-Piputa, Maria Kaczmarek

“…The study includes women with PCOS (n=154), POI (n=40), and control group (n=196) with normal ovarian function (NOF). Blood samples were collected to measure AMH and FSH. …”
Get full text

Streptococcal periorbital necrotizing fasciitis: Case series on a rare but potentially life-threatening entity by Isabella D. Baur, Isabel Habert, Monica Markstaller, Kathrin Hartmann, Arthur Mueller

“…Results: Biomarkers of inflammation in blood samples were elevated at admission and Streptococcus pyogenes was cultured in all three cases. …”
Get full text

Relationship of Serum IL-12 to Inflammation, Hematoma Volume, and Prognosis in Patients With Intracerebral Hemorrhage by Yazhao Zhang, Yanan Tian, Jianhui Wei, Yi Xiang

“…Interleukin-12 (IL-12) promotes brain inflammation, and regulates coagulation mediated by red blood cells and platelets. This study was designed to investigate the relationship of serum IL-12 to inflammation, hematoma volume, and prognosis in ICH patients. …”
Get full text

An retrospective study on the effects of deep learning model-based optimization emergency nursing on treatment compliance and curative effect of patients with acute left heart fail... by Qian Dai, Jing Huang, Hui Huang, Lin Song

“…Results The optimization group showed shorter durations for first aid, hospitalization, electrocardiography, vein channel establishment, and blood collection compared to the conventional group. …”
Get full text

An Effect of Ursodeoxycholic Acid on Inflammation, Steatosis and Liver Fibrosis and Atherogenesis Factors in Patients with Non-Alcoholic Fatty Liver Disease: Results of the USPEH S... by M. V. Mayevskaya, M. Yu. Nadinskaia, V. D. Lunkov, I. Yu. Pirogova, E. V. Chesnokov, Kh. B. Kodzoeva, V. T. Ivashkin

“…The use of UDCA in patients with NAFLD led to a decrease in ALT (p < 0.001), AST (p < 0.001) and GGT (p < 0.001) activity; total cholesterol concentration (p < 0.001); triglycerides (p < 0.001); and LDL (p < 0.001) in the blood and the FLI liver steatosis index (p < 0.001). …”
Get full text

Investigation of the Protective Effects of Taurine against Alloxan-Induced Diabetic Retinal Changes via Electroretinogram and Retinal Histology with New Zealand White Rabbits by Samuel Tung-Hsing Chiang, Shang-Min Yeh, Yi-Chen Chen, Shiun-Long Lin, Jung-Kai Tseng

“…Rabbits were randomly assigned into groups: Group I (vehicle administration only); Group II (diabetes: induced by 100 mg/kg alloxan injection); Group III (diabetes and fed with 200 mg/kg taurine); and Group IV (diabetes and fed with 400 mg/kg taurine). The body weight and blood glucose levels of the rabbits were monitored weekly. …”
Get full text

Circadian Clock Gene Bmal1: A Molecular Bridge from AKI to CKD by Songyuan Yang, Zehua Ye, Lijia Chen, Xiangjun Zhou, Wei Li, Fan Cheng

“…AKI is characterized by an abrupt decrease in glomerular filtration rate (GFR), generally associated with elevated serum creatinine (sCr), blood urea nitrogen (BUN), and electrolyte imbalances. …”
Get full text

The Role of Antioxidant Activity of Chitosan-Pinus merkusii Extract Nanoparticle in against Lead Acetate-Induced Toxicity in Rat Pancreas by G. Wardani, Ernawati, K. Eraiko, S. A. Sudjarwo

“…The male rats used were divided into a control group (treated with distilled water), lead acetate group (injected with lead acetate at 20 mg/kg BW i.p), and the treatment group (treated orally with Chitosan-Pinus merkusii nanoparticle at 150 mg; 300 mg; 600 mg/kg BW and injected with lead acetate at 20 mg/kg BW i.p). Blood samples were taken to measure glucose and insulin level. …”
Get full text

Quality monitoring of resuscitative endovascular balloon occlusion of the aorta using cumulative sum analysis in Korea: a case series by Hyunsik Choi, Joongsuck Kim, Kwanghee Yeo, Ohsang Kwon, Kyounghwan Kim, Wu Seong Kang

“…The pre-TC (n=12) and TC (n=19) periods did not differ significantly with regard to Injury Severity Score, age, injury mechanism, initial systolic blood pressure, prehospital cardiopulmonary resuscitation (CPR), or CPR in the emergency department. …”
Get full text

Comparison of Vitamin and Mineral Usage Status of Patients Applying to Family Health Centres Before and After Covid by Mercan Yağız, Hatice Cakir

“…These participants again stated that it is necessary to check the blood levels of vitamins and minerals (77.4%) and that too much is harmful (81%). …”
Get full text

The Association between Standardized Serum 25-Hydroxyvitamin D Concentration and Risk of Anemia: A Population-Based Cross-Sectional Study by Yang Zhang, Xiaotong Wang, Jia Wang, Weiwei Hu, Xiaolu Song, Ding Yuan, Xianliang Yan

“…Additionally, the association between serum 25(OH)D concentration and red blood cell (RBC) count and hemoglobin (HB) levels was investigated using generalized additive models with smooth functions. …”
Get full text

Early mucosal sensing of SIV infection by paneth cells induces IL-1β production and initiates gut epithelial disruption. by Lauren A Hirao, Irina Grishina, Olivier Bourry, William K Hu, Monsicha Somrit, Sumathi Sankaran-Walters, Chris A Gaulke, Anne N Fenton, Jay A Li, Robert W Crawford, Frank Chuang, Ross Tarara, Maria L Marco, Andreas J Bäumler, Holland Cheng, Satya Dandekar

“…At 2.5 days post-SIV infection, low viral loads were detected in peripheral blood and gut mucosa without CD4+ T cell loss. However, immunohistological analysis revealed the disruption of the gut epithelium manifested by decreased expression and mislocalization of tight junction proteins. …”
Get full text