Antioxidant Potential of Adiponectin and Full PPAR-γ Agonist in Correcting Streptozotocin-Induced Vascular Abnormality in Spontaneously Hypertensive Rats by Sheryar Afzal, Munavvar Abdul Sattar, Edward James Johns, Olorunfemi A. Eseyin, Ali Attiq

“…Diabetic SHRs pretreated with pioglitazone and adiponectin separately exerted improvements in antioxidant enzyme activities, abrogated arterial stiffness, and offset the increased production of reactive oxygen species and dyslipidemic effects of STZ, whereas the blood pressure values were significantly reduced in the irbesartan-treated groups (all P<0.05). …”
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Establishment of Early Multi-Indicator Prediction Models of Moderately Severe Acute Pancreatitis and Severe Acute Pancreatitis by Shan-Shan He, Dan Li, Qi-Yong He, Xiao-Ping Chen, Yong-Xu Lin, Yun-Wen Yu, Feng-Lin Chen, Jian Ding

“…Seven prognostic indicators were selected for incorporation into models, including white blood cell count, lactate dehydrogenase, C-reactive protein, triglyceride, D-dimer, serum potassium, and serum calcium. …”
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IVIG Effects on Erythrocyte Sedimentation Rate in Children by Farhad Salehzadeh, Ahmadvand Noshin, Sepideh Jahangiri

“…Erythrocyte sedimentation rate (ESR) is a valuable laboratory tool in evaluation of infectious, inflammatory, and malignant diseases. Red blood cells in outside from the body precipitate due to their higher density than the plasma. …”
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Quantitative photoacoustic imaging using known chromophores as fluence marker by Anjali Thomas, Max Rietberg, Mervenur Akkus, Gijs van Soest, Kalloor Joseph Francis

“…Here, we propose a method that leverages known chromophores (e.g., arterial blood) to improve the accuracy of quantitative photoacoustic imaging. …”
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Establishment of subcutaneous transplantation platform for delivering induced pluripotent stem cell-derived insulin-producing cells. by Hong Thuan Tran, Watchareewan Rodprasert, Irma Padeta, Saranyou Oontawee, Steven Dwi Purbantoro, Anatcha Thongsit, Parkpoom Siriarchavatana, Sayamon Srisuwatanasagul, Hiroshi Egusa, Thanaphum Osathanon, Chenphop Sawangmake

“…Further preliminary in vivo testing on subcutaneous IPC-bead transplantation in an induced type I diabetic mouse model showed beneficial trends on blood glucose control and survival rate sustainability of diabetic mice. …”
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Laboratory analysis of 124 chronic lymphocytic leukemia cases: Single center study by Shams Salah Mahdi, Nuha Abd Ali Al-Sarai

“…Data were collected from reports over 2 years (April 2022-April2024), including demographics, Hb levels, WBC counts, platelet counts and expression of CD markers (5, 19, 20, 23, 200, FMC7, LAIR1 and others) using flow cytometry on peripheral blood specimens. Based on FC findings, patients were categorized into two groups for better assessment; definite diagnosis CLL and possible diagnosis CLL; then further subdivided into poor prognosis CLL and good prognosis CLL. …”
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Shear Stress Counteracts Endothelial CX3CL1 Induction and Monocytic Cell Adhesion by Aaron Babendreyer, Lisa Molls, Daniela Dreymueller, Stefan Uhlig, Andreas Ludwig

“…Reduced shear stress resulting from disturbed blood flow can drive the development of vascular inflammatory lesions. …”
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Investigation of Interactions between Thrombin and Ten Phenolic Compounds by Affinity Capillary Electrophoresis and Molecular Docking by Qiao-Qiao Li, Yu-Xiu Yang, Jing-Wen Qv, Guang Hu, Yuan-Jia Hu, Zhi-Ning Xia, Feng-Qing Yang

“…Thrombin plays a vital role in blood coagulation, which is a key process involved in thrombosis by promoting platelet aggregation and converting fibrinogen to form the fibrin clot. …”
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Comparing different timings of tourniquet application in total knee arthroplasty: effects on postoperative pain and bone cement interface by Wenbin Wu, Le Cao, Kai Sun, Hongyi Wang

“…The general epidemiological data, tourniquet pressure and duration, postoperative VAS scores, osteotomy surface preparation, blood loss, transfusion rate, KSS scores, knee flexion deformity, knee and thigh circumference differences, and perioperative complications were analyzed and compared among the three groups. …”
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Hematopoietic Stem and Progenitor Cell Expansion in Contact with Mesenchymal Stromal Cells in a Hanging Drop Model Uncovers Disadvantages of 3D Culture by Olga Schmal, Jan Seifert, Tilman E. Schäffer, Christina B. Walter, Wilhelm K. Aicher, Gerd Klein

“…Here, we describe a simplified 3D hanging drop model for the coculture of cord blood-derived CD34+ hematopoietic stem and progenitor cells (HSPCs) with bone marrow-derived mesenchymal stromal cells (MSCs). …”
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Surviving prematurity: retrospective longitudinal study of multisystem consequences in preterm-born individuals from infancy to adolescence by Ruta Morkuniene, Ruta Levuliene, Vilmantas Gegzna, Egle Marija Jakimaviciene, Janina Tutkuviene

“…Results Most diagnoses occurred by age 7, with eye diseases, congenital malformations, and infections most prevalent, but the greatest disparities with the general population were in blood, nervous system, mental, and neoplastic diseases. …”
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Serum free light-chain concentration and relationship with some characteristics of patients with multiple myeloma by Van Nguyen-Thanh Phan, Loc Thi Cao, Minh Duc Tong, Trung Hoang Nguyen, Kha Van Tran, Dung Trong Le

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Effects of Ginseng and Echinacea on Cytokine mRNA Expression in Rats by Deniz Uluışık, Ercan Keskin

“…While the C group was fed a standard rat diet (Purina) ad libitum for a period of 40 days, the G and E groups animals received the same diet containing 0.5 g/kg of Panax ginseng root powder and 0.75 g/kg of Echinacea purpurea root powder, respectively. Blood samples were obtained from 8 rats in each group after 20 and 40 days of treatment, and the mRNA expression of IL-10, TNF-α, and TGF-β1 was determined. …”
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Gut microbiota in the association between obesity and kidney function decline: a metagenomics-based study in a rat model by Akehu Alemasi, Lijiang Gu, Yilun Zhou

“…Metagenomic analysis of intestinal flora was performed.Results The HFD group demonstrated significantly increased levels of creatinine and urea nitrogen in the peripheral blood. Additionally, the HFD rats exhibited a significantly larger glomerular diameter compared to the ND group, accompanied by the presence of glomerulosclerosis, tubular vacuolar transformation, and other pathological changes in certain glomeruli. …”
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Integrated care teams in primary care improve clinical outcomes and care processes in patients with non-communicable diseases by Pei Lin Hu, Cynthia Yan-Ling Tan, Ngoc Hoang Long Nguyen, Rebekah Ryanne Wu, Juliana Bahadin, Nivedita Vikas Nadkarni, Ngiap Chuan Tan

“…The ICT cohort was more likely to achieve treatment goals for systolic blood pressure (SBP) (adjusted odds ratio [AOR] = 1.52, 95% confidence interval [CI] = 1.38–1.68), low-density lipoprotein cholesterol (AOR = 1.72, 95% CI = 1.49–1.99), and glycated haemoglobin (AOR = 1.28, 95% CI = 1.09–1.51). …”
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Biologic Agents in Crohn’s Patients Reduce CD4+ T Cells Activation and Are Inversely Related to Treg Cells by Eliane Aparecida Rosseto-Welter, Leticia D’argenio-Garcia, Filipa Blasco Tavares Pereira Lopes, Ana Eduarda Zulim Carvalho, Fernando Flaquer, Vanessa Severo-Lemos, Claudia Concer Viero Nora, Flavio Steinwurz, Lucas Pires Garcia Oliveria, Thiago Aloia, Luiz Vicente Rizzo, Cristóvão Luis Pitangueira Mangueira, Karina Inacio Carvalho

“…To examine the immune status in a Brazilian cohort, we analyzed CD4+ T cells, activation status, cytokine production, and Treg cells in blood of Crohn’s patients. Patients that underwent biological therapy can recover the percentage of CD4+CD73+ T cells, decrease the CD4+ T cell activation/effector functions, and maintain the peripheral percentage of regulatory T cells. …”
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Clinical Impact of Local Anesthesia on Sedation Stability and Propofol Dosage in Pediatric Dental Sedation by Merve Hayriye Kocaoglu, Çağıl Vural, Betül Büşra Ursavaş

“… Background: Local anesthesia (LA) is often preferred for stabilization of vital signs, depth of anesthesia and pain control in dental restorations but the efficacy of LA administration during deep sedation is controversial.Aim: To retrospectively investigate the effects of LA on heart rate, blood pressure, oxygen saturation, depth of anesthesia and total dose of anesthetic drugs given in pediatric patients sedated for dental procedures.Materials &amp; Methods: Records of 50 healthy children were divided into two groups: Patients who received infiltration LA at the beginning of sedation (Early LA) or who received LA at the end of sedation after completion of restorations (Late LA). …”
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SIV Env RhmAbs + N-803 at ART initiation prolongs viral decay without disrupting reservoir establishment in SIV-infected infant macaques. by Omotayo Farinre, Tzoalli Anaya, Alexis C King, Kedan Endrias, Anne H Hébert, Alison L Hill, Sherrie Jean, Jennifer S Wood, Stephanie Ehnert, Shan Liang, Gregory M Laird, Rosemarie D Mason, Mario Roederer, Jeffrey T Safrit, Maud Mavigner, Ann Chahroudi

“…Levels of intact SIV proviruses in CD4+ T cells from blood, lymph nodes, and rectum at week 48 of ART did not differ across groups. …”
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Right Aortic Arch and Kommerell’s Diverticulum Repaired without Reconstruction of Aberrant Left Subclavian Artery by Hiroshi Osawa, Daisuke Shinohara, Kouan Orii, Shigeru Hosaka, Shoji Fukuda, Okihiko Akashi, Hiroshi Furukawa

“…It has been found advantageous because of a decrease blood loss and a shorter cardiopulmonary bypass duration. …”
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THERAPY FOR LOW BACK PAIN WITH ACUPUNCTURE AND TURMERIC by Farah Dynah Daeq Aszar, Ario Imandiri, Arifa Mustika

“…In She syndrome, lower back pain is often caused by pathogen wind, damp, cold, heat and blood stasis, whereas in the Xi syndrome lower back pain usually caused by deficiency of Jing, Qi, Yin, or Yang of the  kidney. …”
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