A SuperLearner-based pipeline for the development of DNA methylation-derived predictors of phenotypic traits. by Dennis Khodasevich, Nina Holland, Lars van der Laan, Andres Cardenas

“…We gathered publicly available DNAm datasets to generate i) a novel childhood epigenetic clock, ii) a reconstructed Hannum adult blood clock, and iii) as a proof of concept, a predictor of polybrominated biphenyl exposure using the three developmental methodologies. …”
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An Effective Methodology for Diabetes Prediction in the Case of Class Imbalance by Borislava Toleva, Ivan Atanasov, Ivan Ivanov, Vincent Hooper

“…Diabetes causes an increase in the level of blood sugar, which leads to damage to various parts of the human body. …”
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Adjuvant Treatment with Empagliflozin or Semaglutide Increases Endothelial Progenitor Cells in Subjects with Well-Controlled Type 1 Diabetes Mellitus by Maja Preložnik Navodnik, Katarina Reberšek, Katarina Klinar, Andrej Janež, Helena Podgornik

“…As part of a clinical validation, CECs and EPCs were measured in blood samples from 83 subjects with type 1 diabetes (T1DM), evaluating an adjuvant intervention with two different antidiabetic drugs, empagliflozin (N = 28) and semaglutide (N = 29). …”
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Single cell RNA sequencing improves the next generation of approaches to AML treatment: challenges and perspectives by Zahra Khosroabadi, Samaneh Azaryar, Hassan Dianat-Moghadam, Zohreh Amoozgar, Mohammadreza Sharifi

“…Abstract Acute myeloid leukemia (AML) is caused by altered maturation and differentiation of myeloid blasts, as well as transcriptional/epigenetic alterations, all leading to excessive proliferation of malignant blood cells in the bone marrow. Tumor heterogeneity due to the acquisition of new somatic alterations leads to a high rate of resistance to current therapies or reduces the efficacy of hematopoietic stem cell transplantation (HSCT), thus increasing the risk of relapse and mortality. …”
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The Correlation between Hormonal Disturbance in PCOS Women and Serum Level of Kisspeptin by Razaw O. Ibrahim, Shirwan H. Omer, Chro N. Fattah

“…Five milliliter samples of blood from all the patients and control women were obtained twice during the menstrual cycle. …”
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Effects of High Altitude on Sleep and Respiratory System and Theirs Adaptations by Turhan San, Senol Polat, Cemal Cingi, Gorkem Eskiizmir, Fatih Oghan, Burak Cakir

“…During sleep at HA, the levels of CO2 in the blood can drop very low and this can switch off the drive to breathe. …”
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Evaluation of primary health care nurses’ knowledge and neonatal screening performance for phenylketonuria in Alexandria by Esraa Mohammed Abd El-Samie Ismail, Wafaa Mohamed Elarousy, Shaymaa Saeed Mohamed Badawe, Rasha Mohamed Abohadida

“…This is achieved through consult with the child’s provider promptly to arrange a PKU test, accurate collection of blood samples at maternal and child health centers, enable early detection of potential cases. …”
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Disseminated Candida lusitaniae: Nosocomial Acquisition Secondary to an Indwelling Urinary Catheter by Ali Raja, Julia Park

“…He was treated with micafungin, but repeated blood cultures continued to grow C. lusitaniae, and he eventually expired following withdrawal of care. …”
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Accidental intra-arterial injection of enoxaparin sodium leading to abdominal wall expanding subcutaneous hematoma and abdominal wound: case report-vascular by Caroline Howell, Richard Simman, Richard Simman, Richard Simman

“…IntroductionEnoxaparin sodium (Lovenox®) is a commonly used anticoagulant medication that is self-administered via subcutaneous injection to prevent the formation of pathologic blood clots. It is used as a bridge to long-term anticoagulation with warfarin in patients at high risk for thromboembolic events. …”
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Association of XRCC3, XRCC4, BAX, and BCL-2 Polymorphisms with the Risk of Breast Cancer by Emre Ozoran, Fadime Didem Can Trabulus, Duygu Erhan, Bahadir Batar, Mehmet Guven

“…Genetic analysis was performed using peripheral blood samples. Gene polymorphisms were detected by using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) technique. 175 patients and 158 healthy controls were enrolled in the study. …”
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Diagnosis and Assessment of Disease Activity in Takayasu Arteritis: A Childhood Case Illustrating the Challenge by L. Watson, P. Brogan, I. Peart, C. Landes, N. Barnes, G. Cleary

“…Accurate methods of monitoring disease activity or damage are lacking and currently rely on a combination of clinical features, blood inflammatory markers, and imaging modalities. …”
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Specific Activity of Lactate Dehydrogenase in Muscle and Liver Tissues of Rats Exposed to Intermittent Hypobaric Hypoxia by Syarifah Dewi, Adiba Nur Ashri Ramadhani, Khoiriyyah Amalia Az-zahra, Wardaya Wardaya

“…This study aimed to analyze the LDH-specific activity in rat muscle and liver tissue, as well as lactate and glucose levels in blood plasma after intermittent hypobaric hypoxia exposure. …”
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Crude Ethanol Extract of Diospyros mespiliformis Hochst. ex A. DC. Ebenaceae Leaf and Its Fractions Ameliorate Hyperglycemia and Hyperlipidemia in Alloxan-induced Diabetic Rats by Mubarak Muhammad Dahiru, Neksumi Musa

“…The result indicated a significant (p < 0.05) decrease and improvement in fasting blood glucose (FBG) level and body weight, respectively. …”
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Sex-specific association of immunological markers in CS-delivered newborns with pre-pregnancy body mass index and gestational weight gain of mothers by Karolina Rak, Michaela Godyla-Jabłoński, Monika Bronkowska

“…We investigated the relationship of pre-pregnancy body mass index (pBMI) and gestational weight gain (GWG) of mothers with the placental transport rate (PTR) of IgG antibodies and antineutrophil cytoplasmatic antibodies against lactoferrin (Lf-ANCA) and their concentration in umbilical cord blood serum (UCS), verifying the sex-specificity of this relationship. …”
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Serum Triamcinolone Levels following Cervical Interlaminar Epidural Injection by Tim J. Lamer, Rozalin R. Dickson, Halena M. Gazelka, Wayne T. Nicholson, Joel M. Reid, Susan M. Moeschler, W. Michael Hooten

“…The study cohort included eight patients undergoing a fluoroscopically guided C7-T1 interlaminar ESI at a pain medicine specialty clinic. Blood was collected prior to the ESI and on days 1, 2, 4, 6, 8, 14, 21, 28, 35, and 42 following the injection. …”
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Colorectal Cancer Screening in Average Risk Populations: Evidence Summary by Jill Tinmouth, Emily T. Vella, Nancy N. Baxter, Catherine Dubé, Michael Gould, Amanda Hey, Nofisat Ismaila, Bronwen R. McCurdy, Lawrence Paszat

“…Flexible sigmoidoscopy (FS) prevented CRC and led to the largest reduction in CRC mortality with a smaller but significant reduction in CRC mortality with the use of guaiac fecal occult blood tests (gFOBTs). There was insufficient or low quality evidence to support the use of other screening tests, including colonoscopy, as well as changing the ages of initiation and cessation for CRC screening with gFOBTs in Ontario. …”
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Syndecan-4 is More Sensitive in Detecting Hypertensive Left Ventricular Diastolic Dysfunction in 2K2C Rats by Wenyue Dai, Yanqiu Liu, Fengjuan Yao, Wei Li, Jia Liu, Cuiling Li, Donghong Liu

“…The level of SDC-4 and cardiac fibrosis increased gradually as the experiment was processed, and BNP, Tei index, and E/E′ followed to be raised as high blood pressure was maintained after four weeks in the 2K2C hypertension rats. …”
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Bioactive Self‐Assembled Nanoregulator Enhances Hematoma Resolution and Inhibits Neuroinflammation in the Treatment of Intracerebral Hemorrhage by Wenyan Yu, Chengyuan Che, Yi Yang, Yuzhen Zhao, Junjie Liu, Aibing Chen, Jinjin Shi

“…By blocking the CD47‐SIRPα signaling pathway, microglia can rapidly and effectively phagocytose red blood cells (RBCs), thereby promoting the clearance of the hematoma. …”
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Rheological monitoring of tau protein polymerisation with acoustic waves sensor by P. Didier, F. Razan, E. Caplain, M. Michiel, C. Delamarche, C. Nogues, J.Y. Le Huerou, S. Serfaty, P. Larzabal

“…The tau protein is present in complex products such as blood and cerebrospinal fluid. The experimental results show that the acoustic wave system allows to differentiate between tau protein solutions with different states of polymerisation.…”
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Insights from in vivo preclinical cancer studies with histotripsy by Tejaswi Worlikar, Timothy Hall, Man Zhang, Mishal Mendiratta-Lala, Michael Green, Clifford S. Cho, Zhen Xu

“…Histotripsy has been evaluated for various preclinical applications requiring noninvasive tissue removal including cancer, brain surgery, blood clot and hematoma liquefaction, and correction of neonatal congenital heart defects. …”
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