The Multifaceted Role of Extracellular Vesicles in Glioblastoma: microRNA Nanocarriers for Disease Progression and Gene Therapy by Natalia Simionescu, Radu Zonda, Anca Roxana Petrovici, Adriana Georgescu

“…Furthermore, GB-derived EVs have distinct miRNA contents and are able to penetrate the blood–brain barrier. Numerous studies have attempted to identify EV-associated miRNA biomarkers in serum/plasma and cerebrospinal fluid, but their collective findings fail to identify reliable biomarkers that can be applied in clinical settings. …”
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A Mysterious Gram-Positive Rods by Javzandulam Natsag, Zaw Min, Yasir Hamad, Bassel Alkhalil, Atiq Rahman, Richard Williams

“…Unexpectedly, gram positive rods grew out on day five on multiple blood cultures, which were later identified as Mycobacterium fortuitum. …”
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Recurrent Multivalvular Staphylococcus Lugdunensis Endocarditis Causing Complete Heart Block after TAVR by Preeti Singhal, Somsupha Kanjanauthai, Wilson Kwan

“…Transthoracic echocardiogram was not demonstrative of vegetation. Blood cultures were positive for Staphylococcus lugdunensis. …”
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The validity of serum autotaxin as a predictor of hepatic fibrosis in patients with nonalcoholic fatty liver disease by Muhammad Abdel-Gawad, Hamdiy Mahfouz, Mona Abdelmeguid, Gehad M.A.-A. Hassan, Marwa Khalaf, Hani S. Aboalam

“…Regarding lab data, higher cholesterol, low-density lipoproteins, lower high-density lipoproteins level, and triglycerides levels were in males (P< 0.05) with nonsignificant change regarding fasting glucose, hemoglobin A1C, AST, ALT, AST/ALT ratio, Albumin, HB, white blood cell, and Platelet (P>0.05). Conclusion ATX showed poor validity in the prediction of hepatic fibrosis in cases with NAFLD disease, there was a statistically significant increase prevalence of hypertension among females compared with males, an important change was found among males and females regarding NAFLD fibrosis-score, and grade of fibrosis by fibro-scan.…”
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IGFBP2 and IGFBP4 interact to activate complement pathway in diabetic kidney disease by Jieling Liang, Yangxiao Huang, Daping Peng, Yali Xie, Yifei Liu, Xiuxia Lu, Junfa Xu

“…Overactivation of the complement pathway in DKD remains poorly understood.Methods Blood samples were collected from patients for proteomic analysis, complemented by both in vitro and in vivo experiments to investigate the roles of IGFBP2, IGFBP4, and the complement pathway in DKD.Results Elevated levels of IGFBP2 and IGFBP4 were observed in DKD patients. …”
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Vitronectin regulates focal adhesion turnover and migration of human placenta-derived MSCs under nutrient stress by Srishti Dutta Gupta, Nitish Pal, Malancha Ta

“…At sites of tissue damage and wound healing, the mesenchymal stem cells (MSCs) are often challenged by nutrient availability due to blood supply disruption. Thus, it becomes critical to identify novel factors and their mechanism of action in regulating the adhesion and migration of MSCs under nutrient stress condition for successful clinical application. …”
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Metabolic Syndrome, Obesity, and Gastrointestinal Cancer by Shintaro Fujihara, Hirohito Mori, Hideki Kobara, Noriko Nishiyama, Mitsuyoshi Kobayashi, Makoto Oryu, Tsutomu Masaki

“…Metabolic syndrome is a cluster of metabolic abnormalities and is defined as the presence of three or more of the following factors: increased waist circumference, elevated triglycerides, low high-density lipoprotein cholesterol, high blood pressure, and high fasting glucose. Obesity, which is accompanied by metabolic dysregulation often manifested in the metabolic syndrome, is an established risk factor for many cancers. …”
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Impact of Mouthwash-Induced Oral Microbiome Disruption on Alzheimer's Disease Risk: A Perspective Review by Ayoub Boulares, Hela Jdidi, Nicola Luigi Bragazzi

“…This disruption can lead to increased blood pressure, a major risk factor for AD. Given the established connection between hypertension and AD, the long-term use of CHX mouthwash may indirectly contribute to the onset of AD. …”
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Comparing The Viral Load of Severe Acute Respiratory Syndrome Coronavirus 2 in Different Human Specimens by Ali Hattem Hussain

“…For the non-respiratory specimen, stool and rectal swab are most appropriate specimens followed by blood. The urine is not appropriate specimen for viral load detection due to very low sensitivity. …”
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The impact of gut microbiome on neuro-autoimmune demyelinating diseases by Pouria Abolfazli, Cristina Nkene Apue Nchama, Brandon Lucke-Wold

“…Gut dysbiosis promotes the generation of proinflammatory Th17 cells, contributing to blood–brain barrier (BBB) disruption and central nervous system (CNS) autoimmunity. …”
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Vertigo as the First Sign of Chronic Myeloid Leukemia: A Case Report and Literature Review by Rubén Martín-Hernández, Diego Hernando Macías-Rodríguez, Víctor Martín-Sánchez, Cristina Cordero-Civantos, Santiago Santa Cruz-Ruiz, Ángel Batuecas-Caletrio

“…The complementary studies revealed an abnormally high level of leukocytes. A peripheral blood cytogenetic analysis is performed due to a high suspicion of leukemia, and the results show BCR/ABL fusion gene with a cut point in the M-BCR region, which confirms the diagnosis of chronic myeloid leukemia. …”
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A case of kidney graft injury during cesarean section in a pancreas and kidney transplantation recipient by Noriko Aida, Eiji Nishio, Takao Sekiya, Naohiro Aida, Taihei Ito, Takashi Kenmochi, Haruki Nishizawa

“…Cesarean section was indicated when the patient’s blood pressure was 150/100 mmHg at 37 weeks. We pushed the uterine fundus during delivery of the infant, with our usual caution. …”
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Clinical and Radiological Outcomes of Corrective Surgery on Adult Spinal Deformity Patients: Comparison of Short and Long Fusion by Koichiro Ono, Kazuo Ohmori, Takeshi Hori

“…Group L had shorter operation time, smaller intraoperative estimated blood loss, and shorter postoperative hospitalization days. …”
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Dermoscopic and Histopathological Association in Pyogenic Granuloma: A Case Series in Skin of Color by Balachandra Suryakant Ankad, Anirudh A Mallapur, Sahana S Hurakadli

“…Histopathology showed dilated blood vessels in a lobular arrangement (96.7%), hyperplastic epithelium forming a collarette (73.3%), and collagen bundles (56.7%). …”
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Wilson Disease in a Turkish Population: Molecular Insights into an Old Disease with Reported and Novel Variants by Abdullatif Bakır, Vehap Topçu, Büşranur Çavdarlı

“…DNA samples were extracted from peripheral blood. The molecular genetic diagnosis was performed using the next-generation sequencing method. …”
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TESTING OF EMULSION VACCINES BASED ON WHITE OILS OBTAINED AS A RESULT OF HYDROCATALYTIC PROCESSING OF OILSTOCK by I. V. Pigoleva, A. S. Sharypov, T. N. Shabalina, S. V. Zaglyadova, M. V. Kitova, S. A. Antonov, V. V. Mikhalishin, V. A. Starikov, D. V. Mikhalishin

“…Tests results were compared with the ones for a foreign analogue. Blood samples were taken from animals before vaccination and 14 days after it to obtain sera which were further tested for FMD antibodies using VNT. …”
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Pretreatment Pan-Immune-Inflammation Value Efficiently Predicts Survival Outcomes in Glioblastoma Multiforme Patients Receiving Radiotherapy and Temozolomide by Erkan Topkan, Ahmet Kucuk, Ugur Selek

“…Each eligible patient’s PIV was calculated using the findings of peripheral blood platelet (P), monocyte (M), neutrophil (N), and lymphocyte (L) counts obtained on the first day of therapy: PIV=P×M×N÷L. …”
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A Multi-ingredient Supplement Reduced Markers of Muscle Damage after a Rugby Match in Collegiate Male Players by Chang-Li Hsueh, Wang-Shiang Huang, Chen-Kang Chang

“…A total of 13 participants, eight forward and five backs, with a mean height of 1.76 ± 0.08 m and a mean weight of 86.0 ± 22.8 kg, were included. Blood samples were collected before, immediately, 24 h, and 48 h after the match. …”
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Clinical efficacy and safety of high-intensity focused ultrasound combined with ultrasound-guided suction curettage at different time intervals for Cesarean scar pregnancy: a retro... by Yan Peng, Yu Dai, Cuili Wen, Guiyuan Yu, Ping Jin

“…The study compared and analyzed the clinical characteristics, treatment success rates, and intraoperative hemorrhage during ultrasound-guided suction curettage.Results The demographic characteristics of the two groups were similar, with no statistically significant differences observed in HIFU parameters, treatment success rates, blood loss, the use of Foley catheter balloons, or hospital expenses (p > 0.05). …”
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Epigenetic regulation of the nuclear genome associated with mitochondrial dysfunction in Leber’s hereditary optic neuropathy (LHON) by Aswathy P. Nair, Ambika Selvakumar, Janani Gopalarethinam, B. Abishek Kumar, Balachandar Vellingiri, Mohana Devi Subramaniam

“…We isolated peripheral blood mononuclear cells (PBMCs) from LHON patients and healthy individuals and examined epigenetic modifications in ND4 mutant cells and control cells. …”
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