Exploration of Potent Human α-Glucosidase Inhibitors Using In Silico Approaches: Molecular Docking, DFT, Molecular Dynamics Simulations, and MMPBSA by Jyoti Bashyal, Bimal Kumar Raut, Siddha Raj Upadhyaya, Kabita Sharma, Niranjan Parajuli

“…Although commercially available drugs effectively lower blood glucose levels to mitigate hyperglycemia, their associated gastrointestinal side effects necessitate the exploration of explicit inhibitors with minimal side effects. …”
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Capability of biodentine and the mineral trioxide aggregate mta sealing in furcal perforation repair. Literature review by Silvana Benavides, Alejandra Guallo, Yecenia Carrillo

“…An ideal perforation repair material , should create an adequate seal, be biocompatible, not be affect by blood contamination, be a bactericide, radiopaque, induce bone formation and healing, induce mineralization, cementogenesis, facilite its manipulation and application. …”
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Efficacy of Moxibustion in the Treatment of Parkinson’s Disease Based on Meta-Analysis under Intelligent Medical Treatment by Qianqian Niu, Weijie Xu

“…Moxibustion can improve the patient’s blood circulation and help the patient’s local limbs to recover more easily and can help improve the patient’s motor function.…”
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Dysregulated Functions of Lung Macrophage Populations in COPD by Theodore S. Kapellos, Kevin Bassler, Anna C. Aschenbrenner, Wataru Fujii, Joachim L. Schultze

“…To date, alveolar and interstitial resident macrophages as well as blood monocytes have been described in the lungs of patients with COPD contributing to disease pathology by changes in their functional repertoire. …”
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Inhibitory effect of taspine derivative TAD1822-7 on tumor cell growth and angiogenesis via suppression of EphrinB2 and related signaling pathways by Liu Rui, Yu Runze, Cui Yuxin, Fan Mengying, Wang Bo, Zhang Yanmin

“…TAD1822-7 effectively inhibited blood vessel formation in an aortic ring assay to examine angiogenesis. …”
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Structural and functional alterations in hematological parameters among individuals at clinically high risk for acute lymphocytic leukemia by Mohd Afzal, Abhishek Sharma, Ashok Kumar Sah, Aksh Chahal

“…Alterations in hematological markers, such as elevated white blood cell counts, decreased hemoglobin levels, and thrombocytopenia, are indicative of the aggressive nature of high-risk ALL. …”
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Arenobufagin suppresses the progression of early-stage hepatocellular carcinoma by inhibiting EpCAM-mediated tumor stemness by Lijuan Deng, Lifang Zou, Chunhong Zhou, Fuqin Yang, Fen Ouyang, Yingru Zhu, Huihui Cao, Min Hu, Xiaoshen Zhang, Junshan Liu

“…Moreover, arenobufagin inhibited early progression of HCC through EpCAM in a zebrafish xenograft tumor model mimicking early-stage hepatocellular carcinoma without blood vessels in vivo . This study supports a tumor-promoting role of EpCAM in early-stage hepatocellular carcinoma by facilitating cancer stemness and suggests that arenobufagin might be promising candidate for EpCAM inhibition.…”
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COVID-19: Impact in endothelial function and therapy with Mesenchymal Stromal Cells by Carla Longo de Freitas, Priscilla Yuri Okochi Alves da silva, Maria do Carmo Pinho Franco, Danilo Candido de Almeida

“…However, the permissiveness of blood vessels during SARS-CoV-2 infection remains unclear, but regardless endothelial infection, the vascular disfunction may occurred in response to molecular inflammatory signaling triggered by immune cells that attempt to limit infection. …”
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Incidental diagnosis of intra-lobar pulmonary sequestration in an asymptomatic young male: A case report by Prabin Duwadee, MBBS, Suraj Sharma, MD, Radiology, Prabin Kumar Bam, MBBS, Amrit Bhusal, MBBS, Tek Nath Yogi, MBBS, Tilak Khatri, MBBS, Sajiva Aryal, MBBS, Pratick Shrestha, MBBS

“…The sequestration receives its blood supply from anomalous systemic circulation in contrast to pulmonary circulation and can manifest in either intrapulmonary or extrapulmonary forms. …”
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Porphyric encephalopathy in a 15-year-old girl: A case report by Saihari S Dukkipati, Jordan Terschluse, Drew Thodeson, Angela Beavers, Melissa Muff-Luett, Claire Ives, Sookyong Koh

“…She was noted to have dark red-colored urine with no red blood cells. Her urine porphobilinogen level was markedly elevated, consistent with the diagnosis of acute intermittent porphyria. …”
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Modulation of empathic abilities by the interplay between estrogen receptors and arginine vasopressin by Rui Du, Ting Liang, Guofang Lu

“…AVP, key in regulating water balance, blood pressure, and social behaviors, interplays with these receptors, profoundly impacting empathic responses. …”
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Extramedullary Hematopoiesis in a Sentinel Lymph Node as an Early Sign of Chronic Myelomonocytic Leukemia by Joslin M. Bowen, Anamarija M. Perry, Erin Quist, Mojtaba Akhtari

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Conditional similarity triplets enable covariate-informed representations of single-cell data by Chi-Jane Chen, Haidong Yi, Natalie Stanley

“…In order to translate immune signatures assayed from blood or tissue into powerful diagnostics, machine learning approaches are often employed to compute immunological summaries or per-sample featurizations, which can be used as inputs to models for outcomes of interest. …”
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Limited Renal Intravascular Lymphoma: A Case Report and Review of the Literature by Guillermo Enrique Quintero Vega, Daniel Osorio, José Antonio de la Hoz Valle, Daniela Rodríguez Feria

“…It is characterized by the proliferation of cancerous cells into the intraluminal space of the blood vessels. It has a low incidence rate of 0.095 cases per 1,000,000. …”
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The effect of melatonin on coagulation parameters in rats with cerulein-induced acute pancreatitis by Ercan Keskin, Deniz Uluışık

“…Animals of group IV received two intraperitoneal injections of cerulein (50 μg/kg and 25 μg/kg bw, respectively) at two hours intervals and the rats received an intraperitoneal injection of 50 mg/kg melatonin 30 min before each cerulein injection. In blood samples taken from all animals, platelet, fibrinogen, activated partial thromboplastin time (APTT), prothrombin time (PT), international normalized ratio (INR) levels were determined.…”
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A Rare Case of Eosinophilic Granulomatosis with Polyangiitis Associated with Cryoglobulinemia Presenting with a Bullous Skin Eruption of the Lower Limbs by D. D. K. Abeyaratne, C. Liyanapathirana, C. L. Fonseka, P. W. M. C. S. B. Wijekoon

“…She had bilateral ankle edema with frothyuria and a recent onset wheeze. Blood investigations revealed a marked peripheral eosinophilia with positive P-ANCA. …”
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Fetomaternal Outcome in Severe Preeclamptic Women Undergoing Emergency Cesarean Section under Either General Or Spinal Anesthesia by Suman Chattopadhyay, Ashok Das, Subrata Pahari

“…Intraoperatively SA group required more intravenous fluid and vasopressor support, while GA group required more preoperative labetalol injection for blood pressure control. Overall 13.3% of patients required critical care, particularly GA group (44.4% versus 7.5%; P<0.001). …”
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Noninvasive markers of inflammatory bowel disease activity by A. V. Nikitin, L. V. Vasilyeva, Anatoly A. Matiukhin

“…Original study included 67 patients with UC and CD in whom clinical and endoscopic activity of the disease with assessed by histological investigation of biopsy specimens. Blood serum cytokines: IL-4, IL-8, tumor necrosis factor α (TNF-α) and fecal calcium binding protein (calprotectin) were assessed. …”
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Arsenic contamination in GBM plains with a focus on Bihar, India: risks and remediation by Nishita Ivy

“…A significant correlation was found between maximum As levels in water and blood. Food items particularly wheat could play a significant role in As exposure apart from drinking water. …”
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Innovation of CRAM flap for reconstruction of high-voltage electrical burn injuries: Case series by Kawilarang Bertha, Putu Riasa I.Nyoman

“…The rectus abdominis muscle is a donor of musculocutaneous flap due to the well-known blood supply and high vascularity. The rectus abdominis pedicled flap can be either performed transversely or vertically oriented. …”
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