Secreted PD-L1 alleviates inflammatory arthritis in mice through local and systemic AAV gene therapy by Wenjun Li, Wenjun Li, Junjiang Sun, Susi Feng, Ariana La Rosa, Panli Zhang, Eveline Y. Wu, Richard Loeser, Chengwen Li, Chengwen Li, Chengwen Li

“…The levels of pro-inflammatory cytokines in blood were also significantly decreased in shPD-L1 treated mice. …”
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Plateau hypoxia improves tumor immune microenvironment and inhibits subcutaneous tumor growth of colorectal cancer by ZHAO Sijie, WANG Meng, GAO Yuan

“…After the tumor tissues， spleen and blood samples were collected in the C57BL/6 mice. …”
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Evaluation of in-vitro and in-silico antidiabetic potential, glucose metabolism, antioxidant, cytotoxicity and phytochemical content of Ipomoea bolusiana Schinz and Ipomoea crassip... by Garland Kgosi More, Nolitha Nkobole, Charmy Twala, Sechaba Machedi, Tebogo Amos Moswetsa, Ramakwala Christinah Chokwe

“…Background: Diabetes Mellitus is a chronic metabolic disorder caused by genetic disorders and other factors such as the use of certain medications, pancreatic injury, and autoimmune diseases such as rheumatoid arthritis and high blood pressure. However, several therapeutic agents are currently used to manage blood sugar levels, thus reducing the risk of complications. …”
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Effect of different dietary oil sources on the performance, egg quality and antioxidant capacity during the late laying period by Mengmeng Xu, Le Liu, Zongze Fan, Lizhu Niu, Wenxi Ning, He Cheng, Mengyun Li, Wenying Huo, Pan Zhou, Hongyu Deng, Wen Chen, Long Che

“…Compared to the T4 group, the addition of linseed oil to the diet significantly reduced the blood malondialdehyde content and increased the blood glutathione peroxidase (GSH-PX) and superoxide dismutase enzyme activity. …”
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Upregulation of Cardiac IL-10 and Downregulation of IFN-γ in Balb/c IL-4−/− in Acute Chagasic Myocarditis due to Colombian Strain of Trypanosoma cruzi by Marcos Vinicius da Silva, Vera Lúcia de Almeida, Wendyson Duarte de Oliveira, Natália Carasek Matos Cascudo, Pollyana Guimarães de Oliveira, Crislaine Aparecida da Silva, Aline Cristina Souza da Silva, Maria Luíza Gonçalves dos Reis Monteiro, Rosana Rosa Miranda Correa, Milton Adriano Pelli Oliveira, Ruy de Sousa Lino-Júnior, Mara Rúbia Nunes Celes, Juliana Reis Machado

“…Subsequently, cytokines TNF-α, IL-12p70, IL-10, IFN-γ, and IL-17 were measured in the blood, culture supernatant, and heart apex by ELISA. …”
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Seroconversion and dynamics of IgG anti-SARS-CoV-2 antibodies during the pandemic: A two-month observation cohort study on the population of Sleman in Indonesia. by Jajah Fachiroh, Septi Kurnia Lestari, Dewi Kartikawati Paramita, Bagas Suryo Bintoro, Fatwa Sari Tetra Dewi, Lutfan Lazuardi, Cici Permata Rusadi, Erti Nur Sagenah, Eggi Arguni

“…A community-based survey on demographics, comorbidities and smoking habits were documented at baseline, while a history of vaccination, COVID-19-related symptoms, mobility, and preventive measures, weight and height as well as a venous blood draw, were collected at each visit. The anti-RBD-SARS-CoV-2 IgG antibody concentration from blood plasma was measured using chemiluminescent microplate immunoassay (CMIA). …”
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Effect of Acupuncture on the Expression of Heme Oxygenase 1 and Inflammatory Factors in Rats with Intracerebral Hemorrhage by CHEN Qiuxin, KONG Ying, YU Tingting, ZHANG Yu, LIU Peng, ZHANG Xin

“…The rat model of intracerebral hemorrhage was established by autologous blood injection. The sham operation group received various surgical operations similar to the model group, but no blood injection was performed; the model group received intracerebral hemorrhage model production without any intervention; the acupuncture group was used to create a intracerebral hemorrhage model, and treatment began 12 hours after the model was created. …”
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Characteristics and multi-omics analysis of spontaneous spondyloarthritis in non-human primates: Case report by Lei Cai, Qing Lv, Ronghua Ma, Wei Liu, Yalun Guan, Zhongqiang Huang, Qingyu Liu, Yunfeng Li, Shuhua Liu, Ge Li, Yu Zhang

“…To delve into the pathological and physiological traits of spontaneous non-human primate spondyloarthritis, this study meticulously examined the disease features of this natural disease model through an array of techniques including X-ray imaging, MRI imaging, blood biochemistry, markers of bone metabolism, transcriptomics, proteomics, and metabolomics. …”
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Robotic Versus Open Pancreatoduodenectomy With Vein Resection and Reconstruction: A Propensity Score-Matched Analysis by Niccolò Napoli, MD, PhD, FEBS, Emanuele Federico Kauffmann, MD, PhD, FEBS, Michael Ginesini, MD, Armando Di Dato, MD, Virginia Viti, MD, Cesare Gianfaldoni, MD, Lucrezia Lami, MD, Carla Cappelli, MD, Maria Isabella Rotondo, MD, Daniela Campani, MD, Gabriella Amorese, MD, Caterina Vivaldi, MD, Silvia Cesario, MD, Laura Bernardini, MD, Enrico Vasile, MD, Fabio Vistoli, MD, PhD, FEBS, Ugo Boggi, MD, FEBS

“…Robotic PD-VR was associated with longer operative time (611.1 ± 13.9 minutes vs 529.0 ± 13.0 minutes; P < 0.0001), more type 2 vein resection (28.6% vs 5.7%; P = 0.0234) and less type 3 vein resection (31.4% vs 71.4%; P = 0.0008), longer vein occlusion time (30 [25.3–78.3] minutes vs 15 [8–19.5] minutes; P = 0.0098), less blood loss (450 [200–750] mL vs 733 [500–1070.3] mL; P = 0.0075), and fewer blood transfusions (intraoperative: 14.3% vs 48.6%; P = 0.0041) (perioperative: 14.3% vs 60.0%; P = 0.0001). …”
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Immunomodulatory Effects of Combination Therapy with Bushen Formula plus Entecavir for Chronic Hepatitis B Patients by Long-Shan Ji, Qiu-Tian Gao, Ruo-Wen Guo, Xin Zhang, Zhen-Hua Zhou, Zhuo Yu, Xiao-Jun Zhu, Ya-Ting Gao, Xue-Hua Sun, Yue-Qiu Gao, Man Li

“…In addition, peripheral blood mononuclear cells were separated from blood samples in 56 patients and 11 healthy donors. …”
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Delta radiomics modeling based on CTP for predicting hemorrhagic transformation after intravenous thrombolysis in acute cerebral infarction: an 8-year retrospective pilot study by Xiaxia Wu, Xiaxia Wu, Jinfang Yang, Jinfang Yang, Xianqun Ji, Yingjian Ye, Ping Song, Lina Song, Peng An, Peng An

“…Hemodynamic parameters such as cerebral blood volume (CBV), cerebral blood flow (CBF), and time to peak (TTP) were obtained using CTP techniques. …”
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The hidden impact of modern life on D-dimer level: An experimental study by Attiyah Sama

“…High fat diet, electrostatic noise, and deficit of sleep were applied seperatelly for each group under investigation. Blood was collected and plasma D-dimer level was assessed at the end of each week. …”
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Inclusive mentorship of pediatric trainees: pediatric oncology as a microcosm by Sadhana Jackson, Sadhana Jackson, Jessica W. Tsai, Jessica W. Tsai, Kyle L. MacQuarrie, Kyle L. MacQuarrie

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Beta-adrenergic blocking agents in cutaneous and oral melanoma by Sivakamavalli Jeyachandran

“…Beta-adrenergic blocking agents, or beta-blockers, are primarily used to manage cardiovascular conditions such as hypertension, heart failure, and arrhythmias by blocking the effects of stress hormones on beta-adrenergic receptors, reducing heart rate and blood pressure. Recent research highlights their potential impact on cancer, including cutaneous and oral melanoma. …”
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Zeatin Elicits Premature Erythrocyte Senescence Through Calcium and Oxidative Stress Mediated by the NOS/PKC/CK1α Signaling Axis by Iman A. Alajeyan, Jawaher Alsughayyir, Mohammad A. Alfhili

“…Chemotherapy-induced anemia is a major side effect of anticancer therapy secondary to premature senescence of red blood cells (RBCs). Herein, we investigated the biochemical and molecular mechanisms underlying ZTN action in human RBCs. …”
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The Response of Corneal Endothelial Cells to Shear Stress in an In Vitro Flow Model by Sujuan Duan, Yingjie Li, Yanyan Zhang, Xuan Zhu, Yan Mei, Dongmei Xu, Guofu Huang

“…Corneal endothelial cells are usually exposed to shear stress caused by the aqueous humour, which is similar to the exposure of vascular endothelial cells to shear stress caused by blood flow. However, the effect of fluid shear stress on corneal endothelial cells is still poorly understood. …”
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Granulocytic Sarcoma by AML M4eo (inv16) after Allogeneic Stem Cell Transplantation without Bone Marrow Involvement by Stephan Zaenker, Stefan Schweyer, Justin Hasenkamp, Lorenz Truemper, Gerald Wulf

“…We report the case of a patient with recurrences of AML M4eo leukaemia in the uterus and the small intestine at 3 and 5 years, respectively, after matched related peripheral blood stem cell transplantation (PBSCT). The patient underwent the withdrawal of immunosuppression, hysterectomy, and local irradiation at first relapse, as well as systemic chemotherapy and donor lymphocyte infusions at second recurrence, inducing a second and third complete remission, respectively. …”
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CircRNAs as Possible Potential Biomarkers for Breast Cancer Prognosis and Chemotherapy Response: A Comprehensive Study by Saba Mirzaei, Mahdieh Salimi, Hossein Mozdarani

“…Methods: In this observation, the expression of 3 unique circRNAs - cdr1as, circRNA-000284, circ-ITCH - within the peripheral blood of breast cancer patients was studied using Real-Time RT-PCR before and after chemotherapy compared with the control.   …”
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FREQUENCY OF NEONATAL SEPSIS AMONG NEONATES PRESENTING WITH SEIZURES by Abid Imran, Sijad-Ur- Rehman, Imran Qadir, Kainaat Sheikh, Romana Bibi, Muhammad Idrees

“…From all neonates, 5cc of venous blood was obtained under strict aseptic technique and was sent to hospital laboratory for measuring the TLC, Absolute neutrophil count, CRP and platelet count to confirm the presence or absence of neonatal sepsis.   …”
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Knowledge, attitudes, and practices toward COVID-19 and its prevention among medical and dental students in an educational institution in Telangana by Preeti U. Deshpande, Anuradha Basavaraju, Nagapraveen Veerapu, Ashish Akula

“…Knowledge gaps were discovered in the areas of COVID-19 transmission through blood, World Health Organization (WHO)-designated variants of concern, disinfectant usage, and mandatory vaccination. …”
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