Associations between milk infrared-predicted plasma biomarkers of stress resilience and fertility in dairy cattle: Insights for enhancing breeding programs and herd management by Alessio Cecchinato, Hugo Toledo-Alvarado, Lucio Flavio Macedo Mota, Vittoria Bisutti, Erminio Trevisi, Riccardo Negrini, Sara Pegolo, Stefano Schiavon, Luigi Gallo, Giovanni Bittante, Diana Giannuzzi

“…The blood metabolites (15 blood biomarkers related to hepatic damage and function, oxidative stress, inflammation, and innate immunity) were predicted using milk Fourier-transform mid-infrared (MIR) spectroscopy. …”
Get full text

Transient lymphocyte count decrease correlates with oncolytic adenovirus efficacy in humans: mechanistic and biomarker findings from TUNIMO phase I trial by Tuomo Alanko, Akseli Hemminki, Víctor Cervera-Carrascón, Riikka Havunen, Kristian Taipale, Dafne C A Quixabeira, Jorma Sormunen, Katriina Peltola, Suvi Sorsa, Santeri A Pakola, Elise Jirovec, Lyna Haybout, Claudia Kistler, Tatiana V Kudling, Victor Arias, James H A Clubb, Mirte van der Heijden, Teijo Pellinen, Joao M Santos

“…Biological samples from patients were collected in the form of blood and tumor biopsies. Collected samples were analyzed with immunohistochemistry, transcriptomics, proteomics, and flow cytometry.Results TILT-123 induced cyclical decreases in blood lymphocyte count, and more substantial blood lymphocyte count correlated with better radiographical response and longer OS. …”
Get full text

Toxicity of standing milkvetch infected with Alternaria gansuense in white mice by Bo Yang, Zhi Biao Nan, Yan Zhong Li

“…There were significantly higher of lactate dehydrogenase concentration (p < 0.001), while the blood urea nitrogen was lower in the mice fed DPF than those fed HPF and CMF at 3 weeks. …”
Get full text

Stem cells prevent long-term deterioration of renal function after renal artery revascularization in a renovascular hypertension model in rats by Nikolas Waack, Tatiana Guirao, Edgar Maquigussa, Erika Nishi, Milene Ormanji, Olinda Ykuta, Mirian Boim

“…Revascularization constitutes the most efficient therapy for normalizing blood pressure (BP) and has significant benefits for renal function; however, the tissue damage caused by chronic hypoxia is not fully reversed. …”
Get full text

Laboratory Risk Indicator for Necrotizing Fasciitis of the Oro-Cervical Region (LRINEC-OC): A Possible Diagnostic Tool for Emergencies of the Oro-Cervical Region by Masaru Ogawa, Satoshi Yokoo, Yu Takayama, Jun Kurihara, Takaya Makiguchi, Takahiro Shimizu

“…The Laboratory Risk Indicator for Necrotizing Fasciitis (LRINEC) score based on blood test data has recently been proposed as an auxiliary diagnostic tool. …”
Get full text

Prevalence and immunopathologic characteristics of seropositive and seronegative hepatitis B virus-associated membranous nephropathy: a retrospective study of 420 biopsy-proven cas... by Haitao Lu, Qianqian Xu, Guming Zou, Hongmei Gao, Yue Yang, Wenge Li, Li Zhuo

“…The seropositive group exhibited higher blood creatinine values and incidence of liver function abnormalities than the seronegative group (p < .05). …”
Get full text

Development and Evaluation of a Hypertension Prediction Model for Community-Based Screening of Sleep-Disordered Breathing by Feng T, Shan G, Hu Y, He H, Pei G, Zhou R, Ou Q

“…Hypertension was diagnosed using blood pressure monitoring or self-reported antihypertensive medication use. …”
Get full text

Progenitor Hematopoietic Cells Implantation Improves Functional Capacity of End Stage Coronary Artery Disease Patients with Advanced Heart Failure by Yoga Yuniadi, Yuyus Kusnadi, Lakshmi Sandhow, Rendra Erika, Dicky A. Hanafy, Caroline Sardjono, R. W. M. Kaligis, Manoefris Kasim, Ganesja M. Harimurti

“…Patients with symptomatic heart failure despite guideline directed medical therapy and LVEF less than 35% were included. Peripheral blood mononuclear cells were isolated, cultivated for 5 days, and then harvested. …”
Get full text

Quality of Care for Patients with Type 2 Diabetes Mellitus in Dubai: A HEDIS-Like Assessment by Shelagh M. Szabo, Katherine M. Osenenko, Lara Qatami, Bonnie M. Korenblat Donato, Ellen E. Korol, Abdulrazzaq A. Al Madani, Fatheya F. Al Awadi, Jaber Al-Ansari, Ross Maclean, Adrian R. Levy

“…Screening for glycosylated haemoglobin (HbA1c), low-density lipoprotein (LDL), blood pressure, retinopathy, and nephropathy was considered. …”
Get full text

Polymorphism of lipid exchange genes in some populations of South and East Siberia by L. E. Tabikhanova, L. P. Osipova, E. N. Voronina, A. O. Bragin, M. L. Filipenko

“…Indigenous peoples of Siberia have a specific genetically determined type of metabolism supporting such lipid blood parameters that favor increased consumption (in comparison with Caucasians) of animal products. …”
Get full text

Recurrent nocturnal hypoglycemic hemiplegia: a case report and review of the literature by Hanako Toyama, Kazuyuki Takahashi, Tatsunori Shimizu, Izumi Otaka, Sakiko Abe, Shunsuke Kato, Sayaka Ando, Takehiro Sato, Tsukasa Morii, Hiroki Fujita, Hironori Waki

“…He was hypoglycemic with a blood glucose level of 56 mg/dL (3.1 mmol/L). Following glucose administration, the patient’s symptoms resolved within several hours. …”
Get full text

Clinical inertia and treatment intensification among patients with type ii diabetes mellitus at Debre Tabor comprehensive specialized hospital, Ethiopia: an institutional-based cro... by Samuel Berihun Dagnew, Samuel Agegnew Wondm, Getachew Yitayew Tarekegn, Abebe Tarekegn Kassaw, Tilaye Arega Moges

“…BackgroundPeople with type 2 diabetes mellitus who have clinical inertia often struggle to control their blood sugar levels and do not receive timely treatment intensification. …”
Get full text

The Implications of Multiple Repeat Cesarean Deliveries on Maternal Morbidity by Esra Can, Süleyman Cemil Oğlak

“…CONCLUSIONS: Pregnant women having multiple repeat CDs have a significantly increased risk of dense adhesions, placenta previa, PAS, intraoperative massive hemorrhage, blood transfusion, bladder injury, additional surgical interventions, including uterine artery ligation, internal iliac artery ligation, cesarean hysterectomy, and maternal ICU admission. …”
Get full text

Deciphering In Vitro and In Vivo Pharmacological Properties of Seed and Fruit Extracts of Flacourtia jangomas (Lour.) Raeusch by Farhana Alam Ripa, Fowzia Alam, Fahmida Haque Riya, Yesmin Begum, Sharmin Akter Eti, Nusratun Nahar, Zebunnesa Ahmed, Sabrina Sharmin

“…The thrombolytic activity was assessed through rapid clot analysis of human blood samples, revealing that SFJC demonstrated the highest thrombolytic activity (60.99 ± 2.28%) compared to streptokinase (72.89 ± 2.19%). …”
Get full text

Efficacy of Chinese Herbal Medicine in the Treatment of Moderate-Severe Painful Diabetic Peripheral Neuropathy: A Retrospective Study by Yujiao Zheng, Fan Yang, Lin Han, Xiaowen Gou, Fengmei Lian, Wenke Liu, Linhua Zhao, Bing Pang, Xiyan Zhao, Xiaolin Tong

“…The change in patients’ blood glucose level during the whole treatment was also evaluated. …”
Get full text

The effect of preoperative deep breathing exercise with incentive spirometer initiated in the preoperative period on respiratory parameters and complications in patients underwent... by Hatice Öner Cengiz, Zeynep Uluşan Özkan, Eylem Gani

“…Primary outcomes included respiratory rate, oxygen saturation, arterial blood gas parameters, posteroanterior chest X-ray, and evaluation of postoperative pulmonary complications development. …”
Get full text

Base editing HbS to HbG-Makassar improves hemoglobin function supporting its use in sickle cell disease by Zachary Kostamo, Manuel A. Ortega, Chavonna Xu, Patricia R. Feliciano, Elizabeth Budak, Daisy Lam, Valerie Winton, Rebecca Jenkins, Archita Venugopal, Margaret Zhang, John Jamieson, Brent Coisman, Kennedy Goldsborough, Britney Hernandez, Celeste K. Kanne, Erica N. Evans, Jordan Zgodny, Yankai Zhang, Jawa Darazim, Ashwin Patel, Michael A. Pendergast, John Manis, Adam J. Hartigan, Giuseppe Ciaramella, Seung-Joo Lee, S. Haihua Chu, Vivien A. Sheehan

“…However, the quality and functionality of purified HbG and of mature HbGG and HbGS red blood cells (RBC) has not been assessed. Here, we develop a mouse model to characterize HbG. …”
Get full text

Comparative efficacy of GLP-1 RAs/SGLT-2 inhibitors in reducing cardiovascular events in type 2 diabetes according to baseline use of metformin: a systematic review and meta-analys... by Yuxin Zhang, Zhaoji Li, Yongchen Hao

Get full text

Lifestyle scores and their potential to estimate the risk of multiple non-communicable disease-related endpoints: a systematic review by Jie Ding, Ruojin Fu, Tanwei Yuan, Hermann Brenner, Michael Hoffmeister

“…Healthy lifestyle scores including additional risk factors (i.e., blood pressure, blood glucose, and waist circumference) aside from major risk factors (i.e., Body Mass Index (BMI), smoking, and diet) seemed to have a stronger ability to estimate NCDs risk than scores including only major risk factors. …”
Get full text

Comparison of Hemodynamic Response following Spinal Anesthesia between Controlled Hypertensive and Normotensive Patients Undergoing Surgery below the Umbilicus: An Observational Pr... by Leake Gebrargs, Bereket Gebremeskel, Bacha Aberra, Assefa Hika, Yusuf Yimer, Misrak Weldeyohannes, Suleiman Jemal, Degena Behrey, Abere Tilahun

“…The objective of the study was to compare blood pressure and heart rate changes following spinal anesthesia between controlled hypertensive and normotensive patients undergoing surgery below the umbilicus at Black lion hospital, Addis Ababa, Ethiopia, 2020. …”
Get full text