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Density functional theory and molecular dynamics simulation-based bioprospection of Agathosma betulina essential oil metabolites against protein tyrosine phosphatase 1B for interventive antidiabetic therapy
Published 2025-02-01“…While conventional antihyperglycemic medications like biguanides, sulfonylureas, and other agents are commonly used, their long-term use can have side effects, prompting research into natural alternatives. This study bioprospects the antidiabetic potential of metabolites in Agathosma betulina (Buchu) essential oil through computational analysis of their ability to inhibit protein tyrosine phosphatase 1B (PTP1B), a therapeutic diabetes target. …”
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Synthetic peptides as valuable and versatile tools for research: our 20 year journey in Chile
Published 2024-10-01Subjects: Get full text
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Design, synthesis and biological evaluation of buthutin derivatives as cardioprotective agents
Published 2025-02-01“…Natural Products and Bioprospecting…”
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Chimie des substances naturelles et pharmacie : à la croisée des chemins
Published 2024-04-01“…This “account” article seeks to shed light on current issues and challenges, through a critical analysis ranging from bioprospecting to the marketing of new drugs.…”
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Mini-review on the antimicrobial potential of actinobacteria associated with seagrasses
Published 2024-02-01“…Seagrasses appear to be a key ecosystem within the coastal environment worth bioprospecting for novel natural products. Unfortunately, literature about the bioactive potential of their associated prokaryotes, including actinobacteria remains limited. …”
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