Formulation and pharmaceutical development of quetiapine fumarate sustained release matrix tablets using a QbD approach by Gavan Alexandru, Porfire Alina, Marina Cristina, Tomuta Ioan

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Three-dimensional Middle Infrared Spectroscopy Study on Crystalline and Amorphous Structures and Thermostability of Corn, Wheat, and Pea Starch by KONG Xiao-mei, DU Lin-nan, JIANG Meng-wei, CHAI Jia-xin, CHANG Mei-ling, ZHANG Yong, CHANG Ming, XU Yuan-yuan

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Leveraging Next-Generation Sequencing Application from Identity to Purity Profiling of Nucleic Acid-Based Products by Rucha Wadapurkar, Swarda Deo, Renuka Khanzode, Ajay Singh

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Liposome-Encapsulated Bioactive Guttiferone E Exhibits Anti-Inflammatory Effect in Lipopolysaccharide-Stimulated MH-S Macrophages and Cytotoxicity against Human Cancer Cells by Jean Paul Dzoyem, Shashank Reddy Pinnapireddy, Hugues Fouotsa, Jana Brüßler, Frank Runkel, Udo Bakowsky

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Immunogenicity and safety of a COVID-19 DNA vaccine in healthy adults and elderly: A randomized, observer-blind, placebo-controlled phase 2 trial by Siyue Jia, Chengwei Shao, Xin Cheng, Hongxing Pan, Zhijian Wang, Yu Xia, Jianfang Xu, Xuefen Huai, Danjing Leng, Jiarong Wang, Gan Zhao, Bin Wang, Jingxin Li, Fengcai Zhu

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Evaluation of Southern African wild edible plants for potential herb-drug interactions through ex vivo p-glycoprotein and in vitro cytochrome P450 3A4 inhibitory effects by P.S. Kheoane, K.C. Mokhetho, S. Mokhele, K.C. Mbara, C.M. Leonard, T.H. Gadaga, C. Tarirai

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Evaluation of immunomodulatory effects of lamotrigine in BALB/c mice by Abu-Rish Eman Y., Elhayek Shada Y., Mohamed Yehia S., Hamad Islam, Bustanji Yasser

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Roles for Prlhr/GPR10 and Npffr2/GPR74 in feeding responses to PrRP by Yi Wang, Weiwei Qiu, Stace Kernodle, Carly Parker, Marc-Antonio Padilla, Jiaao Su, Abigail J. Tomlinson, Stephanie Oldham, Joss Field, Elise Bernard, David Hornigold, Christopher J. Rhodes, David P. Olson, Randy J. Seeley, Martin G. Myers, Jr

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Applying the Concept of Peptide Uniqueness to Anti-Polio Vaccination by Darja Kanduc, Candida Fasano, Giovanni Capone, Antonella Pesce Delfino, Michele Calabrò, Lorenzo Polimeno

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Folic Acid Is Able to Polarize the Inflammatory Response in LPS Activated Microglia by Regulating Multiple Signaling Pathways by Antonia Cianciulli, Rosaria Salvatore, Chiara Porro, Teresa Trotta, Maria Antonietta Panaro

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Epidemiology of transthyretin (ATTR) amyloidosis: a systematic literature review by Diego Delgado, Firas Dabbous, Nitin Shivappa, Faizan Mazhar, Eric Wittbrodt, Divya Shridharmurthy, Krister Järbrink

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Impact of Ramadan Intermittent Fasting on Oxidative Stress Measured by Urinary 15-F2t-Isoprostane by Mo'ez Al-Islam Ezzat Faris, Rand Nidal Hussein, Ref'at Ahmad Al-Kurd, Mohammed Ahmed Al-Fararjeh, Yasser Khalil Bustanji, Mohammad Khalil Mohammad

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Predictive Ability of Visit-to-Visit Variability of HbA1c Measurements for the Development of Diabetic Kidney Disease: A Retrospective Longitudinal Observational Study by Yunyi Yan, Nozomi Kondo, Kentaro Oniki, Hiroshi Watanabe, Tadashi Imafuku, Yuki Sakamoto, Takuro Shigaki, Akari Maruyama, Hitomi Nakazawa, Tetsuya Kaneko, Ayami Morita, Akira Yoshida, Hitoshi Maeda, Toru Maruyama, Hideaki Jinnouchi, Junji Saruwatari

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Forecasting the effect of water gastric emptying patterns on model drug release in an in vitro glass-bead flow-through system by Felicijan Tjaša, Bogataj Marija

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Chemo-selective modification of cysteine residue: synthesis and application in the discovery of potential drug candidates by Yanyan Liao, Xuefeng Jiang

“…Chemo-select modification of peptides, targeting a handful of the most reactive proteinogenic amino acids (AAs), is gradually utilized to address the medical needs of peptide drugs and biopharmaceuticals. Cysteine (Cys), one of the less abundant AAs in many biological proteins, plays a vital role in the catalysis, signal transduction, and redox regulation of gene expression. …”
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Macro- and Micro-Nutrient Composition and Antioxidant Activity of Chickpea and Pea Accessions by Michela Costantini, Carmine Summo, Mariangela Centrone, Iga Rybicka, Mariagrazia D’Agostino, Paolo Annicchiarico, Francesco Caponio, Stefano Pavan, Grazia Tamma, Antonella Pasqualone

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Selective Gene Transfer to the Retina Using Intravitreal Ultrasound Irradiation by Shozo Sonoda, Katsuro Tachibana, Toshifumi Yamashita, Makoto Shirasawa, Hiroto Terasaki, Eisuke Uchino, Ryo Suzuki, Kazuo Maruyama, Taiji Sakamoto

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Gap Junctions Are Involved in the Rescue of CFTR-Dependent Chloride Efflux by Amniotic Mesenchymal Stem Cells in Coculture with Cystic Fibrosis CFBE41o- Cells by Annalucia Carbone, Roberto Zefferino, Elisa Beccia, Valeria Casavola, Stefano Castellani, Sante Di Gioia, Valentina Giannone, Manuela Seia, Antonella Angiolillo, Carla Colombo, Maria Favia, Massimo Conese

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Practices and knowledge of community pharmacists towards the use of proton pump inhibitors: a cross-sectional study in Jordan by Lobna Gharaibeh, Mariam Ahmad Alameri, Mai I AL-Hawamdeh, Enas Daoud, Randa Atwan, Zainab Lafi, Zainab Zaki Zakaraya

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Performance features of virus removal filters with novel regenerated cellulose hollow fiber membranes by Tomoko Hongo-Hirasaki, Hiroki Fukutomi

“…Following the revision of International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use (ICH) Q5A, the guidelines for the virus safety of biopharmaceuticals now state that an effective viral clearance process should achieve a viral reduction of 4 log10 or greater. …”
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