Emerging natural hemp seed proteins and their functions for nutraceutical applications by Haihong Chen, Bing Xu, Yi Wang, Wei Li, Dong He, Yan Zhang, Xizhen Zhang, Xinhui Xing

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Risk factor assessment of prediabetes and diabetes based on epidemic characteristics in new urban areas: a retrospective and a machine learning study by Li Xu, Xiangcheng Sun, Ning Wang, Yiyi Wang, Yan Li, Chuan Zhang

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Application of the Box–Behnken Design in the Development of Amorphous PVP K30–Phosphatidylcholine Dispersions for the Co-Delivery of Curcumin and Hesperetin Prepared by Hot-Melt Ex... by Kamil Wdowiak, Lidia Tajber, Andrzej Miklaszewski, Judyta Cielecka-Piontek

“…<b>Conclusions:</b> The findings suggest that amorphous PVP K30–phosphatidylcholine dispersions have the potential to improve the biopharmaceutical properties of curcumin and hesperetin.…”
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Utilizing TP53 hotspot mutations as effective predictors of gemcitabine treatment outcome in non-small-cell lung cancer by Yen-Han Tseng, Trieu Thi My Tran, Jinghua Tsai Chang, Yu-Tang Huang, Anh Thuc Nguyen, Ian Yi‑Feng Chang, Yi-Tung Chen, Hao-Wen Hsieh, Yue-Li Juang, Peter Mu-Hsin Chang, Tzu-Yi Huang, Ying-Chih Chang, Yuh-Min Chen, Hsuan Liu, Chi-Ying F. Huang

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Cell clone selection—impact of operation modes and medium exchange strategies on clone ranking by Marie Dorn, Christine Ferng, Kerensa Klottrup-Rees, Kenneth Lee, Martina Micheletti

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How can HPV E6 manipulate host cell differentiation process to maintain the reservoir of infection by Yuwen Chen, Nagayasu Egawa, Ke Zheng, John Doorbar

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Enhancing hepatocellular carcinoma therapy with DOX-loaded SiO2 nanoparticles via mTOR-TFEB pathway autophagic flux inhibition by Huanyu Chen, Jun Liu, Zhichao Cao, Jiajia Li, Hong Zhang, Qianqian Yang, Jian Cheng, Yuxian Shen, Kewu He

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Regulation of senescence-associated secretory phenotypes in osteoarthritis by cytosolic UDP-GlcNAc retention and O-GlcNAcylation by Donghyun Kang, Jeeyeon Lee, Geunho Yook, Sehan Jeong, Jungkwon Shin, Mi-Sung Kim, Yi-Jun Kim, Hyeryeon Jung, Jinsung Ahn, Tae Woo Kim, Moon Jong Chang, Chong Bum Chang, Seung-Baik Kang, Won Ho Yang, Yong-ho Lee, Jin Won Cho, Eugene C. Yi, Chanhee Kang, Jin-Hong Kim

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Evaluation of Recombinant Antibody Production Efficiency in CHO Cells with Sleeping Beauty Transposon Vector System by Pelin Kolçak Yaşlı, Seda Kulabaş, Evren Doruk Engin

“…Chinese hamster ovary (CHO) mammalian cell lines are widely used as cell platforms in biopharmaceutical productions. Different transfection systems are employed for the integration of the target gene cassette into the cell genome and have limitations, such as (i) the integration region in the genome, (ii) the size of the target cassette, and (iii) long selection periods for stable expression. …”
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Sulfate-Reducing Bacteria: Biofilm Formation and Corrosive Activity in Endodontic Files by Fabiano Luiz Heggendorn, Aline Guerra Manssour Fraga, Dennis de Carvalho Ferreira, Lucio Souza Gonçalves, Viviane de Oliveira Freitas Lione, Márcia Teresa Soares Lutterbach

“…The biocorrosive potential of these bacteria will be an important component of a biopharmaceutical under development called BACCOR. Afterwards, four used endodontic files (UEFs) were separately inoculated into a specific culture media for 445 days at 30°C in an incubator. …”
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Antibodies to watch in 2024 by Silvia Crescioli, Hélène Kaplon, Alicia Chenoweth, Lin Wang, Jyothsna Visweswaraiah, Janice M. Reichert

“…Overall, our data suggest that antibody therapeutic development efforts by the biopharmaceutical industry are robust and increasingly successful.…”
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Correction: Risk factors indicating immune-related adverse events with combination chemotherapy with immune checkpoint inhibitors and platinum agents in patients with non-small cel... by Airi Fujimoto, Yoshimichi Koutake, Daisuke Hisamatsu, Noriko Ookubo, Yurika Yabuuchi, Go Kamimura, Tatsuo Kai, Aki Kozono, Takahiro Ootsu, Hiroto Suzuki, Keisuke Matsuo, Kimiko Kuwahara, Yoshita Oiwane, Yuko Nagata, Kenya Tanimoto, Eri Sato, Mei Suenaga, Tomohiro Uehara, Akira Ikari, Satoshi Endo, Yoichi Hiraki, Yosei Kawamata

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Plant Resin Delivery by Nanovectors as an Emerging Approach to Boost Solubility, Permeability and Bioavailability by Eleonora Truzzi, Giulia Vanti, Lucia Grifoni, Eleonora Maretti, Eliana Leo, Anna Rita Bilia

“…Therefore, nanovectors including vesicles, solid lipid nanoparticles, micelles, nanoemulsions, microemulsions and mesoporic nanoparticles have been investigated to optimize the biopharmaceutical properties after topical or oral administration of resins or fractions from them, including essential oils or single constituents. …”
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Mild photothermal therapy for cancer cell modulation: A transformative approach to regulate cancer cell phenotype and enhance therapeutic outcomes by Jinyuan Liu, Steve Smith, Congzhou Wang

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Population genomics of a natural Cannabis sativa L. collection from Iran identifies novel genetic loci for flowering time, morphology, sex and chemotyping by Mahboubeh Mostafaei Dehnavi, Annabelle Damerum, Sadegh Taheri, Ali Ebadi, Shadab Panahi, George Hodgin, Brian Brandley, Seyed Alireza Salami, Gail Taylor

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Investigation of antioxidant, antidiabetic, and antiglycation properties of Sonchus oleraceus and Lobularia maritima (L.) Desv. extracts from Taza, Morocco by Abdelmounaim Laabar, Imad Kabach, Sara El Asri, Amr Kchikich, Soufiane Drioua, Ayoub El Hamri, Moulay El Abbes Faouzi

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Total Organic Carbon Analysis of Residual Contaminants in Bioreactor Equipment: A Cleaning Verification Study using Surface Swabbing by Ciara E. Fitzpatrick, James J. Roche

“…Contamination is a major issue in the biopharmaceutical industry. Bioreactors must be meticulously cleaned to remove residual impurities and avoid cross-contamination. …”
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The role of interleukin-17 in inflammation-related cancers by Xingru Zhang, Xingru Zhang, Bangjie Li, Tian Lan, Tian Lan, Conner Chiari, Xiaoyang Ye, Kepeng Wang, Ju Chen

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Advances, challenges and future applications of liver organoids in experimental regenerative medicine by Da Gong, Jiaye Mo, Jiaye Mo, Mei Zhai, Fulin Zhou, Guocai Wang, Shaohua Ma, Xiaoyong Dai, Xiaoyong Dai, Xuesong Deng

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Application of natural β-glucans as biocompatible functional nanomaterials by Xiaojie Li, Peter Chi Keung Cheung

“…Keywords: β-Glucans, Biocompatibility, Biopharmaceuticals, Nanohybrids…”
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