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361
Foundational contributions of Svetlana Mojsov to the GLP-1 field
Published 2024-10-01“…Biochemist Svetlana Mojsov, both as a graduate student at The Rockefeller University under the mentorship of Bruce Merrifield during the 1970s, and as an independent investigator at the Massachusetts General Hospital (MGH) during the 1980s, devised effective and robust methods for the chemical synthesis of the peptide hormones glucagon and glucagon-like peptide (GLP-1), along with numerous analogues of these key biomolecules. Working separately from MGH’s powerhouse endocrine research laboratory, Mojsov developed a tool-kit of reliable assays that were indispensable to later in vitro and in vivo collaborative studies that established profound insulinotropic effects of this peptide family, findings that were subsequently harnessed clinically with blockbuster drugs directed at often-serious endocrine conditions such as type 2 diabetes and obesity. …”
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362
Linum usitatissimum Delivery over Chitosan Nanobiopolymer: Enhanced Effects on Polycystic Ovary Syndrome Condition
Published 2024-01-01“…As per the results of this investigation, supporting medically important biomolecules over chitosan can enhance their therapeutic effectiveness in controlling PCOS.…”
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363
Development of Antimicrobial Biopolymer Film Incorporated with a Mixture of Sodium Lactate and Diacetate and Studying its Efficacy Against Listeria monocytogenes and Microbiologica...
Published 2025-02-01“…The integration of biomolecules derived from agricultural waste has the potential to enhance the mechanical properties of these novel packaging materials. …”
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364
Synthesis, characterization, In silico, and In vitro studies of CuS–ZnO nanocomposite using mushroom extract
Published 2025-03-01“…Metal oxide, metal sulfide and the reducing ability of biomolecules in the mushroom extract were analysed using FTIR spectroscopy. …”
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365
Growth and metabolic activities of cowpea seedlings exposed to artificial pond wastewaterâtreated soil
Published 2024-01-01“…Results Artificial pond wastewater treatment of soil increased significantly (P<0.05) the growth parameters, content of biomolecules and activities of alpha amylase, starch phosphorylase and peroxidase when compared to the control. …”
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366
Mesenchymal stem cells derived exosomes: a new era in cardiac regeneration
Published 2025-01-01“…Exosomes, extracellular vesicles containing a diverse array of biomolecules, have garnered significant attention for their potential in regenerative medicine. …”
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367
Wound healing potential of green synthesized silver nanoparticles of Glycyrrhiza glabra linn root extract: A preclinical study
Published 2025-03-01“…Conclusion: The current study found that the biomolecules of Glycyrrhiza glabra Linn root alcoholic extract, which are responsible for augmenting the plant extract's capacity to heal wounds, were capped on silver nanoparticles.…”
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368
Development of MHz X-ray phase contrast imaging at the European XFEL
Published 2025-01-01“…We report on recent developments that enable megahertz hard X-ray phase contrast imaging (MHz XPCI) experiments at the Single Particles, Clusters, and Biomolecules and Serial Femtosecond Crystallography (SPB/SFX) instrument of the European XFEL facility (EuXFEL). …”
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369
One-pot green synthesis of BSA-capped O-CQDs as an effective fluorescent sensing platform for sensitive and selective detection of promethazine drug
Published 2025-02-01“…BSA-Caped O-CQDs improve their biocompatibility and stability in physiological conditions while also reducing non-specific interactions with other biomolecules. Several spectroscopic methods, such as fluorescence, X-ray diffraction (XRD) and Fourier-transform infrared spectroscopy (FTIR), were used to evaluate this enhanced specificity and sensitivity. …”
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370
How Significant Are Marine Invertebrate Collagens? Exploring Trends in Research and Innovation
Published 2024-12-01“…The findings reveal that research dates back to the 1970s, and after a period of reduced activity, interest in collagens from several marine invertebrate groups was renewed around 2008, likely driven by the increased commercial interest in these biomolecules of marine origin. Research and development are predominantly reported from China and Japan, highlighting significant research interest in cnidarians (jellyfish), echinoderms (sea cucumbers, sea urchins and starfish), molluscs (squid and cuttlefish) and sponges. …”
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371
Targeted lipidomics analysis of possible molecular mechanisms of lipid changes in temporal lobe epilepsy models
Published 2025-01-01“…BackgroundLipids are vital biomolecules involved in the formation of various biofilms. …”
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372
On‐chip label‐free impedance‐based detection of antibiotic permeation
Published 2021-02-01“…Abstract Biosensors are analytical tools used for the analysis of biomaterial samples and provide an understanding about the biocomposition, structure, and function of biomolecules and/or biomechanisms by converting the biological response into an electrical and/or optical signal. …”
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373
Stimuli-responsive hydrogel dressing for wound healing
Published 2025-01-01“…The wound microenvironment is collectively regulated by internal biomolecules, external drugs, and external sanitation. …”
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374
Comprehensive GC-MS Characterization and Histochemical Assessment of Various Parts of Three <i>Colchicum</i> Species from Bulgarian Flora
Published 2025-01-01“…These findings enhance our understanding of the chemical composition, organ specialization, and potential as a source of new biomolecules in these <i>Colchicum</i> species. They underscore the ecological and pharmacological importance of endemic taxa and provide a framework for future research into their sustainable utilization and potential bioactivities.…”
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375
A Refractive Index-Based Dual-Band Metamaterial Sensor Design and Analysis for Biomedical Sensing Applications
Published 2025-01-01“…This enables the detection of various biomolecules, including cancer cells, glucose, HIV-1, and M13 viruses. …”
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376
Monitoring of enzymatic cleavage reaction of GST-fusion protein on biolayer interferometry sensor
Published 2024-10-01“…Biolayer interferometry (BLI) is an optical sensor-based analytical method primarily used for analyzing interactions between biomolecules. In this study, we explored the application of BLI to observe the cleavage reaction of glutathione S-transferase (GST)-tagged fusion protein by human rhinovirus (HRV) 3C protease on a BLI sensor as a new application of the BLI method. …”
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377
Extraction and Characterization of Artichoke (<i>Cynara cardunculus</i> L.) Solid Waste from the Industrial Processing of Fresh-Cut Products for Nutraceutical Use
Published 2024-12-01“…The artichoke by-products showed high polyphenolic and inulin values, thus representing an important source of health-promoting biomolecules for application in pharmaceutical and cosmeceutical fields. …”
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378
Anti-Tissue-Transglutaminase IgA Antibodies Presence Determination Using Electrochemical Square Wave Voltammetry and Modified Electrodes Based on Polypyrrole and Quantum Dots
Published 2025-01-01“…Tissue transglutaminase protein biomolecules are immobilized on a quantum dots-polypyrrole nanocomposite in the improved electrode. …”
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379
Conducting polymer-based electrochemical sensors: Progress, challenges, and future perspectives
Published 2025-08-01“…Conducting polymers and their nanocomposites-based electrochemical sensors have demonstrated exceptional capabilities towards detecting various biomolecules, heavy metals, pesticides, and viruses like SARS-COV-2. …”
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380
Polystyrene nanoparticles induce DNA damage and apoptosis in HeLa cells
Published 2025-01-01“…Polystyrene nanoplastics (PS-NPs) are the prevalent form of nanoparticles found in the environment and their cellular uptake can cause cytotoxicity and structural alteration of biomolecules. Thus, there is an urgent need for evaluation of the genotoxic effects of PS-NPs on human cell models. …”
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