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A macro-transection model of brain trauma for neuromaterial testing with functional electrophysiological readouts
Published 2025-12-01“…Biomaterial therapies show promise as medical materials for neural repair through immunomodulation, structural support, and delivery of therapeutic biomolecules. However, a lack of facile and pathology-mimetic models for therapeutic testing is a bottleneck in neural tissue engineering research. …”
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322
AMEND 2.0: module identification and multi-omic data integration with multiplex-heterogeneous graphs
Published 2025-02-01“…Biological networks, which represent interactions or associations between biomolecules, have been highly effective in facilitating omic analysis. …”
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Metabolites Profiling of Manilkara mabokeensis Aubrév Bark and Investigation of Biological Activities
Published 2022-01-01Get full text
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325
Online resources on gene networks containing human and animal data
Published 2018-01-01“…In addition, we observed the characteristics of several wellknown databases containing data on interactions between biomolecules of various types. The following characteristics of databases were considered: (1) the types of information accumulated in the databases; (2) methods of data presentation; (3) methods of data collection; (4) data sources; (5) special search tools and options for data analysis. …”
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UCH-L1 Inhibitor Alleviates Nerve Damage Caused by Moyamoya Disease
Published 2024-01-01“…Exosomes are touted as bio-shuttles for the delivery of distinct biomolecules inside the cells. Recently, UCH-L1 was shown to play a vital role in nerve injury. …”
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328
Optimization of In Vivo Studies by Combining Planar Dynamic and Tomographic Imaging: Workflow Evaluation on a Superparamagnetic Nanoparticles System
Published 2021-01-01“…In the present study, we used an iron-based nanoformulation, already established as an MRI/SPECT probe, as well as to load different biomolecules, to investigate its potential for nuclear planar and tomographic imaging of several target tissues following its distribution via different administration routes. …”
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329
M2 Macrophages as a Potential Target for Antiatherosclerosis Treatment
Published 2019-01-01“…Inhibiting or activating some kinds of enzymes, affecting transcription factors, or acting on several membrane receptors could regulate the polarization of the M2 phenotype. Besides, biomolecules, for example vitamin D, were found to affect the process of M2 polarization. …”
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330
Polycaprolactone for Hard Tissue Regeneration: Scaffold Design and In Vivo Implications
Published 2025-01-01“…In the last thirty years, tissue engineering (TI) has emerged as an alternative method to regenerate tissues and organs and restore their function by implanting specific lineage cells, growth factors, or biomolecules functionalizing a matrix scaffold. Recently, several pathologies have led to bone loss or damage, such as malformations, bone resorption associated with benign or malignant tumors, periodontal disease, traumas, and others in which a discontinuity in tissue integrity is observed. …”
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331
Kojic Acid Derivative as an Antimitotic Agent That Selectively Kills Tumour Cells
Published 2024-12-01“…Light and electron microscopy observations were supported by the next generation sequencing (NGS), cytoflow, and spectroscopy analysis of mRNA and biomolecules, respectively. <b>Results:</b> The light and electron microscopy observations showed that L1 treatment leads to significant morphological changes in Caco2 cells, which are characteristic of mitosis arrest. …”
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332
Endometrial Cancer Cells Promote M2-Like Macrophage Polarization by Delivering Exosomal miRNA-21 under Hypoxia Condition
Published 2020-01-01“…Exosomes are small membrane vesicles secreted from a variety of cell types which mediate cell-to-cell communication through transported biomolecules. Here, we investigated whether exosomes can play an immunomodulatory role in intercellular communication between EC cells and macrophages. …”
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333
Zinc oxide seed priming enhances drought tolerance in wheat seedlings by improving antioxidant activity and osmoprotection
Published 2025-01-01“…It also leads to dehydration, which increases the oxidation of lipids and membranes and disrupts the functioning of biomolecules in plants. Zinc is an essential element for several enzymes involved in metabolism, cell elongation, preservation of the strength and integrity of cell membranes, seed development, and resistance to environmental stress. …”
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334
Phytochemical analysis and biological activities of solvent extracts and silver nanoparticles obtained from Woodwardia unigemmata (Makino) Nakai.
Published 2025-01-01“…Unigemmata contains numerous bioactive phytochemicals and can be useful as a drug against MDR bacterial strains. These biomolecules covering AgNPs may enhance their biological activities, which can be employed in the treatment of various microbial infections.…”
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335
Oxidative damage to DNA, expression of Mt-1, and activation of repair mechanisms induced by vanadium trioxide in cultures of human lymphocytes
Published 2025-06-01“…Among the vanadium compounds that are found in the environment, vanadium trioxide (V2O3) has attracted interest because of its impact on biomolecules such as DNA, RNA, and proteins. However, its precise mechanism of action remains unclear, although it is suspected to be related to oxidative stress. …”
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Rapid fabrication and dissolution of pressed 58Ni/Mg matrix targets for 55Co production
Published 2025-01-01“…Abstract Background Beyond the use of conventional short-lived PET radionuclides, there is a growing interest in tracking larger biomolecules and exploring radiotheranostic applications. …”
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Silymarin as a Therapeutic Agent for Hepatocellular Carcinoma: A Multi-Approach Computational Study
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RETRACTED ARTICLE: Synthesis of silver nanoparticles using Plantago lanceolata extract and assessing their antibacterial and antioxidant activities
Published 2021-10-01“…The FT-IR analysis indicated the association of biomolecules (phenolic acid and flavonoids) to reduce silver (Ag+) ions. …”
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