The Development and Applications of a Dual Optical Imaging System for Studying Glioma Stem Cells by Po-An Tai MD, PhD, Yen-Lin Liu MD, PhD, Ya-Ting Wen MD, Chien-Min Lin MD, PhD, Thanh-Tuan Huynh MD, PhD, Michael Hsiao DVM, PhD, Alexander T. H. Wu PhD, Li Wei MD, PhD

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Comparison of Glycomacropeptide with Phenylalanine Free-Synthetic Amino Acids in Test Meals to PKU Patients: No Significant Differences in Biomarkers, Including Plasma Phe Levels by Kirsten K. Ahring, Allan M. Lund, Erik Jensen, Thomas G. Jensen, Karen Brøndum-Nielsen, Michael Pedersen, Allan Bardow, Jens Juul Holst, Jens F. Rehfeld, Lisbeth B. Møller

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Predicting immunotherapy efficacy in endometrial cancer: focus on the tumor microenvironment by Liubov A. Tashireva, Irina V. Larionova, Irina V. Larionova, Nikita A. Ermak, Anastasia A. Maltseva, Ekaterina I. Livanos, Anna Yu. Kalinchuk, Marina N. Stakheyeva, Larisa A. Kolomiets

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Functional Skin Grafts: Where Biomaterials Meet Stem Cells by Amtoj Kaur, Swati Midha, Shibashish Giri, Sujata Mohanty

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<i>Pneumocystis</i> Pneumonia Severity Is Associated with Taxonomic Shifts in the Respiratory Microbiota by Valentina Del Prete, Antonia Piazzesi, Matteo Scanu, Francesca Toto, Stefania Pane, Federica Berrilli, Giovangiacinto Paterno, Lorenza Putignani, David di Cave

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Computational analysis for efficient thermal transportation of ternary hybrid nanofluid flow across a stretching sheet with Cattaneo-Christov heat flux model by Wei Li, Shan Ali Khan, Muhammad Shafqat, Qamar Abbas, Taseer Muhammad, Muhammad Imran

“…Binary/ternary hybrid nanofluids are important in industries such as biomedicine, transportation, and pharmaceuticals because of their excellent thermophysical properties. …”
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Identification of a new fish trypanosome from the large yellow croaker (Larimichthys crocea) and description of its impact on host pathology, blood biochemical parameters and immun... by Yang Xiaoao, Qi Pengzhi, Tao Zhen, Zhang Qingwei, Wang Yanjie, Zhu Denghui, Yan Xiaojun, Fu Peipei, Guo Baoying

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Application of the weighted histogram method for calculating the thermodynamic parameters of the formation of oligodeoxyribonucleotide duplexes by I. I. Yushin, V. M. Golyshev, D. V. Pyshnyi, A. A. Lomzov

“…This work opens up new horizons for a rational design of constructs based on NAs for solving problems in biomedicine and biotechnology.…”
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Tailoring cell-inspired biomaterials to fuel cancer therapy by Qi-Hui Wang, Shi Cheng, Chun-Yu Han, Shuang Yang, Sheng-Rui Gao, Wan-Zhong Yin, Wen-Zhi Song

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Deciphering the mechanisms of long non-coding RNAs in ferroptosis: insights into its clinical significance in cancer progression and immunology by Shengming Ou, Xiaoya Nie, Xiangyu Qiu, Xin Jin, Geyan Wu, Rongxin Zhang, Jinrong Zhu

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HDAC1-3 inhibition triggers NEDD4-mediated CCR2 downregulation and attenuates immunosuppression in myeloid-derived suppressor cells by Zhiqi Xie, Jinjin Shao, Zeren Shen, Zhichao Ye, Yoshiaki Okada, Daisuke Okuzaki, Naoki Okada, Masashi Tachibana

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Genome Characteristic of NDM-5-Producing Klebsiella Quasipneumoniae and Klebsiella Pneumoniae in China by Chen L, Liu R, Ye H, Qian J, Lou D

“…Lifeng Chen,1,&ast; Ruishan Liu,2,3,&ast; Haowei Ye,2 Jiajie Qian,4 Danfeng Lou5 1Department of Clinical Engineering and Materials Supplies, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, People’s Republic of China; 2State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, People’s Republic of China; 3Jinan Microecological Biomedicine, Shandong Laboratory, Jinan, People’s Republic of China; 4Department of Gastrointestinal Surgery, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, People’s Republic of China; 5Department of Infectious Diseases, Shulan (Hangzhou) Hospital, Hangzhou, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Danfeng Lou, Department of Infectious Diseases, Shulan (Hangzhou) Hospital, No. 848 Dongxin Road, Hangzhou, People’s Republic of China, Email loudanfeng@126.com Jiajie Qian, Department of Gastrointestinal Surgery, The First Affiliated Hospital, College of Medicine Zhejiang University, No. 79 Qingchun Road, Hangzhou, People’s Republic of China, Email 1202058@zju.edu.cnAbstract: The global dissemination of carbapenem-resistant Enterobacteriaceae poses a significant threat to public health. …”
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Application and development of CRISPR technology in the secondary metabolic pathway of the active ingredients of phytopharmaceuticals by Haixin Gao, Xinyi Pei, Xianshui Song, Shiying Wang, Zisong Yang, Jianjun Zhu, Qiupeng Lin, Qinlong Zhu, Xiangna Yang

“…In summary, CRISPR technology presents broad application prospects in the study of secondary metabolism in medicinal plants and is poised to facilitate further advancements in biomedicine and agricultural science. As technological advancements continue and challenges are progressively addressed, CRISPR technology is expected to play an increasingly vital role in the research of active ingredients in medicinal plants.…”
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Antimicrobial and Antibiofilm Activities of 4,5-Dihydro-1H-pyrazole-1-carboximidamide Hydrochloride against Salmonella spp. by Andressa C. Damim, Danilo Y. de Albuquerque, Fabiana G. S. Dantas, Fernanda Galvão, Melyssa Negri, Lucas Pizzuti, Gleison A. Casagrande, Sumbal Saba, Jamal Rafique, Kelly M. P. de Oliveira

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Generation of Inducible CRISPRi and CRISPRa Human Stromal/Stem Cell Lines for Controlled Target Gene Transcription during Lineage Differentiation by Li Chen, Kaikai Shi, Weimin Qiu, Lars Aagaard, Moustapha Kassem

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Peripheral nerve injury induces dystonia-like movements and dysregulation in the energy metabolism: A multi-omics descriptive study in Thap1+/− mice by Colette Reinhold, Susanne Knorr, Rhonda L. McFleder, Lisa Harder-Rauschenberger, Tom Gräfenhan, Andreas Schlosser, Michael Sendtner, Jens Volkmann, Chi Wang Ip

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Prioritization of biological processes based on the reconstruction and analysis of associative gene networks describing the response of plants to adverse environmental factors by P. S. Demenkov, E. A. Oshchepkova, T. V. Ivanisenko, V. A. Ivanisenko

“…Methods for prioritizing or ranking candidate genes according to their importance based on specific criteria via the analysis of gene networks are widely used in biomedicine to search for genes associated with diseases and to predict biomarkers, pharmacological targets and other clinically relevant molecules. …”
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Long-range organization of intestinal 2D-crypts using exogenous Wnt3a micropatterning by Enara Larrañaga, Miquel Marin-Riera, Aina Abad-Lázaro, David Bartolomé-Català, Aitor Otero, Vanesa Fernández-Majada, Eduard Batlle, James Sharpe, Samuel Ojosnegros, Jordi Comelles, Elena Martinez

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Experimental investigation on large-aspect-ratio zirconia ceramic microchannels by waterjet-assisted laser processing by Qingqing Qiu, Jinjin Han, Aqib Mashood Khan, Rui Ma, Bin He, Linglei Kong, Qilin Li, Kai Ding, Wasim Ahmad, Weining Lei

“…Zirconia (ZrO2) ceramic has excellent mechanical properties and superior chemical stability, making it widely used in aerospace, microelectronics, biomedicine, and mechanical manufacturing. However, due to its difficult-to-machine characteristics, traditional machining methods struggle with fabricating large-aspect-ratio (LAR) microchannels in zirconia ceramics. …”
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Circulating MicroRNAs in Elderly Type 2 Diabetic Patients by Giuseppina Catanzaro, Zein Mersini Besharat, Martina Chiacchiarini, Luana Abballe, Claudia Sabato, Alessandra Vacca, Paola Borgiani, Francesco Dotta, Manfredi Tesauro, Agnese Po, Elisabetta Ferretti

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