Computational Methods to Work as First-Pass Filter in Deleterious SNP Analysis of Alkaptonuria by R. Magesh, C. George Priya Doss

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Aniridia in Two Related Tennessee Walking Horses by Karen A. McCormick, Daniel Ward, Kimberly M. Newkirk

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Neuroinflammation at the Dorsolateral Inferior Medulla: A Possible Central Nervous System Localization for POTS and Long COVID by Svetlana Blitshteyn

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Rethinking scabies in Europe: An ECDC prevention framework approach by Giancarlo Ceccarelli, Francesco Branda, Fabio Scarpa, Mattia Albanese, Gabriella d’Ettorre, Marta Giovanetti, Massimo Ciccozzi

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Gut Microorganism-Mediated Neutralization of Mycotoxins: A Promising Approach to Combat Fungal Toxicity by Md Minarul Islam, Nasir Uddin Mahbub, Mohammad Amirul Islam

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Climate change impacts and pandemics by Shriyansh Srivastava, Rachana Mehta, Aroop Mohanty, Prakasini Satapathy, Ranjit Sah, Vasso Apostoloopoulos

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Reconciling predicted and measured viscosity parameters in high concentration therapeutic antibody solutions by Georgina Bethany Armstrong, Aisling Roche, William Lewis, Zahra Rattray

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Resistance mechanisms to immune checkpoint inhibitors: updated insights by Besan H. Alsaafeen, Bassam R. Ali, Eyad Elkord

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Mucinous Colorectal Carcinoma in a 17-Year-Old Male: A Diagnosis with Low Clinical Index of Suspicion by James Joseph Yahaya, Edward Ketson Msokwa, Alex Mremi

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Poly(3-hydroxybutyrate): Promising biomaterial for bone tissue engineering by Dariš Barbara, Knez Željko

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Research on the Compilation of Mechanical Design Guided Textbooks Based on Chinese University MOOCs by Zhao Xiuting, Liang Ruotian, Wang Ziyue

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A Multidimensional Approach to the Management of Severe Asthma: Inflammometry, Molecular Microbiology and Bronchial Thermoplasty by Conor Cox, Melanie Kjarsgaard, Michael G Surette, P Gerard Cox, Parameswaran Nair

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Isolated Kaposi Sarcoma of the Tonsil: A Case Report and Review of the Scientific Literature by Barbara Pittore, Carlo Loris Pelagatti, Francesco Deiana, Francesco Ortu, Elena Maricosu, Sergio Cossu, Giovanni Sotgiu

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Neuroinflammation and Cerebrovascular Disease in Old Age: A Translational Medicine Perspective by Mario Di Napoli, Imtiaz M. Shah

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Mechanisms underlying CSD initiation implicated by genetic mouse models of migraine by Daniela Pietrobon, K.C. Brennan

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Effectiveness of PK-Guided Personalized Recombinant FVIII Treatment in Patients with Hemophilia A: Clinical Case Experiences Based on an Observational Study by Mizoguchi Y, Hino M, Ueda H, Miyaguchi Y, Kobayashi M

“…Yoko Mizoguchi,1 Moeko Hino,2 Hitoshi Ueda,3 Yasuo Miyaguchi,3 Masao Kobayashi1,4 1Department of Pediatrics, Hiroshima University Graduate School of Biomedical Sciences, Hiroshima, Japan; 2Department of Pediatrics, Chiba University Hospital, Chiba, Japan; 3Japan Medical Office, Takeda Pharmaceutical Company Limited, Tokyo, Japan; 4Japanese Red Cross, Chugoku-Shikoku Block Blood Center, Hiroshima, JapanCorrespondence: Yasuo Miyaguchi, Japan Medical Office, Takeda Pharmaceutical Company Limited, 2 Chome-1-1 Nihonbashihoncho, Chuo-ku, Tokyo, 103-0023, Japan, Tel +81 70-4921-7966, Email yasuo.miyaguchi1@takeda.comPurpose: Prophylaxis with recombinant factor VIII (rFVIII) products is the gold-standard treatment for hemophilia A. …”
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Review of Challenges in Performing Real-World Evidence Studies for Nonprescription Products by Maihöfner C, Mallick-Searle T, Vollert J, Kalita P, Sood Sethi V

“…Christian Maihöfner,1 Theresa Mallick-Searle,2 Jan Vollert,3 Pranab Kalita,4 Vidhu Sood Sethi5 1Department of Neurology, General Fürth Hospital, University of Erlangen, Fürth, Germany; 2Division of Pain Medicine, Stanford Health Care Pain Management Clinic, Palo Alto, CA, USA; 3Department of Clinical and Biomedical Sciences, Faculty of Health and Life Sciences, University of Exeter, Exeter, UK; 4Global Category Medical Affairs, Haleon Plc, Weybridge, England, UK; 5Global Medical Affairs, GSK Consumer Healthcare Singapore Pte. …”
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Dynamic hierarchical ligand anisotropy for competing macrophage regulation in vivo by Kanghyeon Kim, Sunhong Min, Ramar Thangam, Kyong-Ryol Tag, Hyun-Jeong Lee, Jeongyun Heo, Hwapyung Jung, Thet Thet Swe, Iman Zare, Guosheng Song, Alireza Hassani Najafabadi, Junmin Lee, Hyun-Do Jung, Jong Seung Kim, Sunghoon Hur, Hyun-Cheol Song, Sung-Gyu Park, Kunyu Zhang, Pengchao Zhao, Liming Bian, Se Hoon Kim, Juyoung Yoon, Jae-Pyoung Ahn, Hong-Kyu Kim, Heemin Kang

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A deep learning-based ADRPPA algorithm for the prediction of diabetic retinopathy progression by Victoria Y. Wang, Men-Tzung Lo, Ta-Ching Chen, Chu-Hsuan Huang, Adam Huang, Pa-Chun Wang

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Atlas of multilineage stem cell differentiation reveals TMEM88 as a developmental regulator of blood pressure by Sophie Shen, Tessa Werner, Samuel W. Lukowski, Stacey Andersen, Yuliangzi Sun, Woo Jun Shim, Dalia Mizikovsky, Sakurako Kobayashi, Jennifer Outhwaite, Han Sheng Chiu, Xiaoli Chen, Gavin Chapman, Ella M. M. A. Martin, Di Xia, Duy Pham, Zezhuo Su, Daniel Kim, Pengyi Yang, Men Chee Tan, Enakshi Sinniah, Qiongyi Zhao, Sumedha Negi, Meredith A. Redd, Joseph E. Powell, Sally L. Dunwoodie, Patrick P. L. Tam, Mikael Bodén, Joshua W. K. Ho, Quan Nguyen, Nathan J. Palpant

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