Association between lifestyle factors and thyroid function in young sedentary euthyroid adults by Elisa Merchan-Ramirez, Guillermo Sanchez-Delgado, Lucas Jurado-Fasoli, Francisco M Acosta, Manuel Muñoz-Torres, Jose M. Llamas-Elvira, Jonatan R Ruiz

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Clinical and cost-effectiveness of Knee Arthroplasty versus Joint Distraction for Osteoarthritis (KARDS): protocol for a multicentre, phase III, randomised control trial by Deborah D Stocken, Dennis G McGonagle, David Murray, Catherine Reynolds, Catherine Fernandez, David R Ellard, Andrew Metcalfe, Hemant Sharma, Paul Harwood, Hamish Simpson, Hemant Pandit, Susanne Arnold, Cerys Joyce Tassinari, Ruchi Higham, Isabelle Louise Smith, Ruben Mujica-Mota, Thomas William Hamilton, Julie Croft

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Phase 1 study of safety, tolerability, and efficacy of intradermal DNA vaccine ASP2390 in adults allergic to house dust mites by Thomas Kayser, MD, BS, Ronald Smulders, MD, PhD, Tomohiro Kusawake, PhD, Erik Wambre, PhD, Gurunadh R. Chichili, PhD, Mary B. Blauwet, DrPH, Anna Spence, MS, Melanie Patton, BS, Rima Tabash, PhD, Hannah A. DeBerg, PhD, Sugandhika Khosa, MS, Philipp Badorrek, MD, Jens M. Hohlfeld, MD, Brian C. Ferslew, PharmD, PhD

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Older adults’ Internet use behavior and its association with accelerometer-derived physical activity by Yen-Yu Chung, Jiaren Chen, Mei-Chun Lin, Ruo-Lan Liu, Jenn-Bang Wu, Hsin-Chang Tsai, Ting-Fu Lai, Ting-Fu Lai, Yung Liao, Yung Liao, Jong-Hwan Park, Jong-Hwan Park, Jong-Hwan Park

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Motor Neuron Disease Systematic Multi-Arm Adaptive Randomised Trial (MND-SMART): a multi-arm, multi-stage, adaptive, platform, phase III randomised, double-blind, placebo-controlle... by Jeremy Chataway, Suvankar Pal, Charis Wong, Elizabeth Elliott, Jenna M Gregory, Siddharthan Chandran, Judith Newton, Shuna Colville, Maria Stavrou, Christopher J Weir, Nigel Stallard, Malcolm R Macleod, Michelle Steven, Richard Anthony Parker, Arpan R Mehta, Robert J Swingler, Mahesh K B Parmar, Rachel S Dakin, Jill Williamson

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A multistage drug delivery approach for colorectal primary tumors and lymph node metastases by Yihang Yuan, Quanjun Lin, Hai-Yi Feng, Yunpeng Zhang, Xing Lai, Mao-Hua Zhu, Jue Wang, Jiangpei Shi, Yanhu Huang, Lele Zhang, Qin Lu, Zeli Yuan, Jonathan F. Lovell, Hong-Zhuan Chen, Peng Sun, Chao Fang

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A protocol for mobilising novel finance models for collaborative health promotion and disease prevention initiatives: taking a smart capacitating investment approach in the Invest4... by Joanna Lane, Joanna Lane, Rhiannon T. Edwards, Balázs Babarczy, Holly Whiteley, Vidya Oruganti, Vidya Oruganti, Maureen Rutten-van Mölken, Caroline Costongs, Anant R. Jani, Sarah Wordsworth, Alison Maassen, Apostolos Tsiachristas, Jacob Davies, Bengt Stavenow, Jolanda van Vliet, Steve Wright, Steve Wright, Lina Papartyte, Jennifer Catherine Camaradou, Rositsa Koleva-Kolarova

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EULAR standardised training model for ultrasound-guided, minimally invasive synovial tissue biopsy procedures in large and small joints by Annamaria Iagnocco, Andrew Filer, Gabriel Herrero-Beaumont, Peter Balint, Ingrid Moller, Esperanza Naredo, Lene Terslev, Alessandra Bruns, Aurélie Najm, Ana Rodriguez, Raquel Largo, Stefano Alivernini, Jesús Garrido, Maria Antonietta D’Agostino, Jacqueline Uson, Juhani Koski, Maribel Miguel, Carlos Guillén-Astete, David A. Bong, George A.W. Bruyn, Carlos Acebes

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Phase 1, open-label, dose-escalation study on the safety, pharmacokinetics, and preliminary efficacy of intravenous Coxsackievirus A21 (V937), with or without pembrolizumab, in pat... by Christy Ralph, Sumati Gupta, Matthew Zibelman, Brendan D Curti, Kevin J Harrington, Steven J O'Day, Andrew G Hill, David C Campbell, Gavin M Wright, David E Gerber, Jonathan E Rosenberg, Jaime R Merchan, Charles M Rudin, Hardev S Pandha, Wallace L Akerley, Daphne Day, Timothy D Clay, Ross R Jennens, Yixin Ren, Emmett V Schmidt, Lisa Guttman

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Advancing poliovirus eradication: lessons learned from piloting direct molecular detection of polioviruses in high-risk and priority geographies by Paula L. Marcet, Brandon Short, Ashley Deas, Hong Sun, Chelsea Harrington, Shahzad Shaukat, Muhammad Masroor Alam, Marycelin Baba, Adedayo Faneye, Prossy Namuwulya, Lea Necitas Apostol, Tamer Elshaarawy, John Kofi Odoom, Peter Borus, Shelina Moonsamy, Yogolelo Riziki, Marie Claire Endegue Zanga, Mesfin Tefera, Anfumbom K. W. Kfutwah, Salmaan Sharif, Varja Grabovac, Cara C. Burns, Nancy Gerloff

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Fusion of EEG and EMG signals for detecting pre-movement intention of sitting and standing in healthy individuals and patients with spinal cord injury by Chenyang Li, Chenyang Li, Yuchen Xu, Tao Feng, Tao Feng, Minmin Wang, Minmin Wang, Minmin Wang, Xiaomei Zhang, Li Zhang, Li Zhang, Ruidong Cheng, Weihai Chen, Weihai Chen, Weidong Chen, Weidong Chen, Shaomin Zhang, Shaomin Zhang, Shaomin Zhang, Shaomin Zhang

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Prevalence and management of hypertension in Turner syndrome: data from the International Turner Syndrome (I-TS) registry by Shani A D Mathara Diddhenipothage, Katharina J Beck, Gayana Amiyangoda, Jillian Bryce, Luminita Cima, Katya De Groote, Yana Deyanova, Evgenia Globa, Gloria Herrmann, Anders Juul, Anna Sophie L Kjaer, Anette Tønnes Pedersen, Sukran Poyrazoglu, Ursina Probst-Scheidegger, Theo C J Sas, Simona Fica, Sumudu Nimali Seneviratne, Justyna Karolina Witczak, Elizabeth Orchard, Jeremy W Tomlinson, S Faisal Ahmed, Helen E Turner

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Metabolically activated and highly polyfunctional intratumoral VISTA+ regulatory B cells are associated with tumor recurrence in early-stage NSCLC by Domenico Lo Tartaro, Beatrice Aramini, Valentina Masciale, Nikolaos Paschalidis, Francesco Demetrio Lofaro, Anita Neroni, Rebecca Borella, Elena Santacroce, Alin Liviu Ciobanu, Anna Valeria Samarelli, Federica Boraldi, Daniela Quaglino, Alessandra Dubini, Michele Gaudio, Gloria Manzotti, Francesca Reggiani, Federica Torricelli, Alessia Ciarrocchi, Antonino Neri, Federica Bertolini, Massimo Dominici, Pier Luigi Filosso, Franco Stella, Lara Gibellini, Sara De Biasi, Andrea Cossarizza

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Impact of glucocorticoids on patients’ quality of life: a qualitative study assessing face validity and feasibility of the Steroid PRO in patients with inflammatory gastroenterolog... by Shaney L Barratt, Emma Dures, Mwidimi Ndosi, Michelle Sharp, Sebastian E Sattui, Jill Dawson, Susan M Goodman, Sarah L Mackie, Tom Creed, Catherine L Hill, Joanna C Robson, Pamela Richards, Susan Bridgewater, Christine A Silverthorne, Jen Orme, Anne-Marie T Sweeney, Elizabeth Arthurs, Genevieve Osborne, Giles Dunhill, Richard P Ramonell, Timothy Patton

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Dynamics of HDL-Cholesterol Following a Post-Myocardial Infarction Cardiac Rehabilitation Program by Carlos Bertolín-Boronat, Héctor Merenciano-González, Víctor Marcos-Garcés, María Luz Martínez-Mas, Josefa Inés Climent Alberola, Nerea Pérez, Laura López-Bueno, María Concepción Esteban-Argente, María Valls Reig, Ana Arizón Benito, Alfonso Payá Rubio, César Ríos-Navarro, Elena de Dios, Jose Gavara, Juan Sanchis, Vicente Bodi

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Middle-age cerebral small vessel disease and cognitive function in later life: a population-based prospective cohort studyResearch in context by Ali Tanweer Siddiquee, Yoon Ho Hwang, Soriul Kim, Sung Jin Shin, Ji Soo Lee, June Christoph Kang, Min-Hee Lee, Hyeon Jin Kim, Seung Ku Lee, Chol Shin

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Identifying falsified COVID-19 vaccines by analysing vaccine vial label and excipient profiles using MALDI-ToF mass spectrometry by Benediktus Yohan Arman, Rebecca Clarke, Tehmina Bharucha, Laura Gomez Fernandez, John Walsby-Tickle, Michael Deats, Sara Mosca, Qianqi Lin, Sneha Banerjee, Shrikrishna R. Chunekar, Kundan D. Patil, Sunil Gairola, Susanna Dunachie, Hamid A. Merchant, Robert Stokes, Rutendo Kuwana, Alexandrine Maes, Jean-Philippe Charrier, Fay Probert, Céline Caillet, Pavel Matousek, James McCullagh, Paul N. Newton, Nicole Zitzmann, Bevin Gangadharan

“…Abstract The rapid development and worldwide distribution of COVID-19 vaccines is a remarkable achievement of biomedical research and logistical implementation. However, these developments are associated with the risk of a surge of substandard and falsified (SF) vaccines, as illustrated by the 184 incidents with SF and diverted COVID-19 vaccines which have been reported during the pandemic in 48 countries, with a paucity of methods for their detection in supply chains. …”
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Transcriptomic profiles of monocyte-derived macrophages exposed to SARS-CoV-2 VOCs reveal immune-evasion escape driven by delta by Alessia Gallo, Josè Camilla Sammartino, Roberta Vazzana, Roberto Giambruno, Claudia Carcione, Nicola Cuscino, Salvatore Castelbuono, Vitale Miceli, Matteo Bulati, Daniele Lilleri, Irene Cassaniti, Pier Giulio Conaldi, Fausto Baldanti

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International norms for adult handgrip strength: A systematic review of data on 2.4 million adults aged 20 to 100+ years from 69 countries and regions by Grant R. Tomkinson, Justin J. Lang, Lukáš Rubín, Ryan McGrath, Bethany Gower, Terry Boyle, Marilyn G. Klug, Alexandra J. Mayhew, Henry T. Blake, Francisco B. Ortega, Cristina Cadenas-Sanchez, Costan G. Magnussen, Brooklyn J. Fraser, Tetsuhiro Kidokoro, Yang Liu, Kaare Christensen, Darryl P. Leong, Mette Aadahl, Edimansyah Abdin, Julian Alcazar, Aqeel Alenazi, Bader Alqahtani, Cledir De A. Amaral, Thatiana L.M. Amaral, Alex Andrade Fernandes, Peter Axelsson, Jennifer N. Baldwin, Karin Bammann, Aline R. Barbosa, Ameline Bardo, Inosha Bimali, Peter Bjerregaard, Martin Bobak, Colin A. Boreham, Klaus Bös, João Carlos Bouzas Marins, Joshua Burns, Nadezda Capkova, Lilia Castillo-Martínez, Liang-Kung Chen, Siu Ming Choi, Rebecca K.J. Choong, Susana C. Confortin, Cyrus Cooper, Jorge E. Correa-Bautista, Amandine Cournil, Grace Cruz, Eling D. de Bruin, José Antonio De Paz, Bruno De Souza Moreira, Luiz Antonio Dos Anjos, María Cristina Enríquez Reyna, Eduardo Ferriolli, Gillian Forrester, Elena Frolova, Abadi K. Gebre, Atef M. Ghaleb, Tiffany K. Gill, Yasuyuki Gondo, M. Cristina Gonzalez, Citlali Gonzalez Alvarez, Mary K. Hannah, Nicholas C. Harvey, Jean-Yves Hogrel, Marie-Theres Huemer, Toshiko Iidaka, Lewis A. Ingram, Dmitri A. Jdanov, Victoria L. Keevil, Wolfgang Kemmler, Rose Anne Kenny, Dae-Yeon Kim, Tracy L. Kivell, Ingirid G.H. Kjær, Alexander Kluttig, Rumi Kozakai, Danit Langer, Lisbeth A. Larsen, Wei-Ju Lee, David A. Leon, Eric Lichtenstein, Bertis B. Little, Roberto Alves Lourenço, Rahul Malhotra, Robert M. Malina, Kiyoaki Matsumoto, Tal Mazor-Karsenty, Marnee J. McKay, Sinéad McLoughlin, Abhishek L. Mensegere, Mostafa Mohammadian, Virgilio Garcia Moreira, Hiroshi Murayama, Anne Murray, Anita Liberalesso Neri, Claudia Niessner, Gabriel Núñez Othón, Gabriel Olveira, Suzanne G. Orchard, Andrezj Pajak, Chan Woong Park, Julie A. Pasco, Maria E. Peña Reyes, Leani Souza Máximo Pereira, Annette Peters, Eric Tsz-Chun Poon, Margareth C. Portela, Jedd Pratt, Robinson Ramírez-Vélez, Wendy Rodríguez-García, Joanne Ryan, Mauricio A. San-Martín, Francisco José Sánchez-Torralvo, Mahnaz Saremi, Arno Schmidt-Trucksäss, Satoshi Seino, Shamsul Azhar Shah, Marc Sim, Bjørn Heine Strand, Mythily Subramaniam, Charlotte Suetta, Sophia X. Sui, Jonas S. Sundarakumar, Koya Suzuki, Abdonas Tamosiunas, Maw Pin Tan, Yu Taniguchi, Barbara Thorand, Anna Turusheva, Anne Therese Tveter, Jonathan Wagner, Dao Wang, Stuart J. Warden, Julia Wearing, Shiou Liang Wee, Leo D. Westbury, Agnieszka Wiśniowska-Szurlej, Alexander Woll, Noriko Yoshimura, Ruby Yu

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Clinical implementation of next-generation sequencing testing and genomically-matched therapy: a real-world data in a tertiary hospital by Jin Won Kim, Hee Young Na, Sejoon Lee, Ji-Won Kim, Koung Jin Suh, Se Hyun Kim, Yu Jung Kim, Keun-Wook Lee, Jong Seok Lee, Jaihwan Kim, Jin-Hyeok Hwang, Kihwan Hwang, Chae-Yong Kim, Yong Beom Kim, Soomin Ahn, Kyu Sang Lee, Hyojin Kim, Hye Seung Lee, So Yeon Park, Gheeyoung Choe, Jee Hyun Kim, Jin-Haeng Chung

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