Hybrid hydrogels containing gradients in gold nanoparticles for localized delivery of mesenchymal stem cells and enhanced nerve tissues remodeling in vivo by Jie Gao, Yiduo Zhou, Gang Xu, Zhongqing Wei, Liucheng Ding, Wei Zhang, Yi Huang

“…Although promising for promoting nerve regeneration, stem cell therapy still suffers from abundant intrinsic limitations, mainly including excessive ROS in lesions and inefficient production of growth factors (GFs). Biomaterials that scavenge endogenous ROS and promote GFs secretion might overcome such limitations and thus are being increasingly investigated. …”
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Application of Stem Cell Therapy for ACL Graft Regeneration by Canlong Wang, Yejun Hu, Shichen Zhang, Dengfeng Ruan, Zizhan Huang, Peiwen He, Honglu Cai, Boon Chin Heng, Xiao Chen, Weiliang Shen

“…Various differentiation inducers have been widely applied together with stem cells to enhance specific lineage differentiation, such as recombinant gene transfection, growth factors, and biomaterials. Among the various different types of stem cells, bone marrow-derived mesenchymal stem cells (BMSCs) have been investigated the most, while ligament stem progenitor cells (LDSCs) have demonstrated the best potential in generating tendon/ligament lineage cells. …”
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Substrate curvature influences cytoskeletal rearrangement and modulates macrophage phenotype by Austin Sovar, Matthew D. Patrick, Ramkumar T. Annamalai

“…By controlling curvature, therapeutic biomaterials may direct immune responses, offering a new avenue for treating inflammatory diseases. …”
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Potential plant proteins for functional food ingredients: Composition, utilization and its challenges by Paul Ndubuisi Anyiam, Suphat Phongthai, Lutz Grossmann, Young Hoon Jung, Samart Sai-Ut, Ekasit Onsaard, Saroat Rawdkuen

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Effect of non-contact induction heating on HA coatings and bone cement, an ex vivo study [version 2; peer review: 2 approved, 1 approved with reservations] by Robert Kamphof, Dr. Bart G.C.W. Pijls, Dr. Rob G.H.H. Nelissen, Jeroen Mesman-Vergeer, Dr. Giuseppe Cama

“…This study aims to provide insight into the feasibility of using non-contact induction heating on metallic implants that are in direct contact with other biomaterials, such as coatings composed of hydroxyapatite and bone cement composed of poly (methyl methacrylate) (PMMA). …”
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Study on the mechanical properties of Ti-6Al-4V alloy with minimal surface structures: effects of different heat treatment temperatures by Kai Qian, Shuangyu Liu, Fulong Zhang, Guihua Hang, Bo Cui, Ziwei Guo, Qiushi Zhang, Wang Binhua

“…Triply periodic minimal surface (TPMS) structures are widely used in scaffold design for biomaterials due to their excellent porous architecture and mechanical properties. …”
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Clinical Guide Adaptation for Amalgam Waste Management in Dental Settings in Iran by Mahsa Eshrati, Fatemeh Momeniha, Nafiseh Momeni, Elham Ahmadi, Atieh Hashemian, Homa Kashani, Mojgan Alaeddini

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Effects of fiber engraving laser on metallurgical, surface topography, and corrosion properties of AZ80 magnesium-based alloy by Narges Ahmadi, Homam Naffakh-Moosavy, Seyed Mohammad Mahdi Hadavi, Fatemeh Bagheri

“…Surface modification with fiber lasers improves the biological and mechanical properties of biomaterials. Magnesium, a lightweight metal similar to natural bone, shows no toxicity and can aid in hard tissue recovery when implanted in the human body. …”
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Systematic Review and Meta-Analysis of Remineralizing Agents: Outcomes on White Spot Lesions by Ana Josefina Monjarás-Ávila, Louis Hardan, Carlos Enrique Cuevas-Suárez, Norma Verónica Zavala Alonso, Miguel Ángel Fernández-Barrera, Carol Moussa, Jamal Jabr, Rim Bourgi, Youssef Haikel

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Quantitative Evaluation of Bacteria Adherent and in Biofilm on Single-Wall Carbon Nanotube-Coated Surfaces by Fabrizio Pantanella, Francesca Berlutti, Daniele Passeri, Daniela Sordi, Alessandra Frioni, Tiziana Natalizi, Maria Letizia Terranova, Marco Rossi, Piera Valenti

“…Recently, to counteract biofilm development, new nano-structured biomaterials have been proposed. However, data about the antibacterial properties of nano-structured surfaces are fragmentary and controversial, and, in particular, the susceptibility of nano-structured materials to colonization and biofilm formation by bacterial pathogens has not been yet thoroughly considered. …”
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Estimating the Severity of Oral Lesions Via Analysis of Cone Beam Computed Tomography Reports: A Proposed Deep Learning Model by Sare Mahdavifar, Seyed Mostafa Fakhrahmad, Elham Ansarifard

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Intelligent in-cell electrophysiology: Reconstructing intracellular action potentials using a physics-informed deep learning model trained on nanoelectrode array recordings by Keivan Rahmani, Yang Yang, Ethan Paul Foster, Ching-Ting Tsai, Dhivya Pushpa Meganathan, Diego D. Alvarez, Aayush Gupta, Bianxiao Cui, Francesca Santoro, Brenda L. Bloodgood, Rose Yu, Csaba Forro, Zeinab Jahed

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Transforming monosaccharides: Recent advances in rare sugar production and future exploration by Shin-ichi Nakakita, Jun Hirabayashi

“…If we can produce rare sugars as we wish, it is expected that various more useful biomaterials will be created by using them as raw materials. …”
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Halophilic Fungi—Features and Potential Applications by Lyudmila Yovchevska, Yana Gocheva, Galina Stoyancheva, Jeny Miteva-Staleva, Vladislava Dishliyska, Radoslav Abrashev, Tsvetomira Stamenova, Maria Angelova, Ekaterina Krumova

“…Among these extremophiles, filamentous fungi adapted to high-salt environments represent a new and valuable source of enzymes, biomolecules, and biomaterials. While most studies on halophiles have focused on bacteria, reports on filamentous fungi remain limited. …”
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Antimicrobial Activity of Thermocycled Polymethyl Methacrylate Resin Reinforced with Titanium Dioxide and Copper Oxide Nanoparticles by Rashin Giti, Kamiar Zomorodian, Maryam Firouzmandi, Zahra Zareshahrabadi, Sedigheh Rahmannasab

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Influence of Different ECM-Like Hydrogels on Neurite Outgrowth Induced by Adipose Tissue-Derived Stem Cells by E. Oliveira, R. C. Assunção-Silva, O. Ziv-Polat, E. D. Gomes, F. G. Teixeira, N. A. Silva, A. Shahar, A. J. Salgado

“…The data herein presented highlights the importance of biological cues within hydrogel-based biomaterials as possible modulators of ASC secretome and its effects for SCI applications.…”
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pH‐Dependent Assembly and Stability of Toll‐Like Receptor 3/dsRNA Signaling Complex: Insights from Constant pH Molecular Dynamics and Metadynamics Simulations by Penghui Li, Mingsong Shi, Yibo Wang, Qiong Liu, Xiubo Du, Xiaohui Wang

“…This study offers new insights into the molecular mechanisms underlying pH‐dependent immune signaling via higher‐order assemblies and suggests potential applications for histidine in self‐assembling biomaterials.…”
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In Vitro and In Vivo Dentinogenic Efficacy of Human Dental Pulp-Derived Cells Induced by Demineralized Dentin Matrix and HA-TCP by Kyung-Jung Kang, Min Suk Lee, Chan-Woong Moon, Jae-Hoon Lee, Hee Seok Yang, Young-Joo Jang

“…These cells are differentiated into hard tissue by addition of proper cytokines and biomaterials. Hydroxyapatite-tricalcium phosphates (HA-TCPs) are essential components of hard tissue and generally used as a biocompatible material in tissue engineering of bone. …”
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Effects of Drying Treatments on the Physicochemical Characteristics and Antioxidant Properties of the Edible Wild Mushroom <i>Cyttaria espinosae</i> Lloyd (Digüeñe Mushroom) by Marcelo Villalobos-Pezos, Ociel Muñoz Fariña, Kong Shun Ah-Hen, María-Fernanda Garrido Figueroa, Olga García Figueroa, Alexandra González Esparza, Luisbel González Pérez de Medina, José Miguel Bastías Montes

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Comparative Exploration of Antioxidant Properties of Alcalase- and Trypsin-Hydrolyzed Porcine By-Products and Their Classification for Industrial Use by Jun Hwang, Woo-Young Son, Eun Ju Jeong, Kyeong-Soo Kim, Eui-Cheol Shin, Dong-Heon Song, Kyung-Woo Lee, Hyun-Wook Kim

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