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18141
Thermal properties and non-bonded interactions in human PMP2 variants: A molecular dynamics study
Published 2025-01-01“…In this research work, we have done a comparative molecular dynamics study on the PMP2 protein and its M114T mutant variant, focusing on non-bonded interactions and thermal properties in a biologically relevant environment. The primary objective was to explore the structural differences between the two proteins at temperatures of 305 K, 310 K, and 315 K. …”
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18142
Biopsychosocial evaluation of patients with multiple sclerosis using a short set of categories of the international classification of functioning, disability and health, and its re...
Published 2018-09-01“…However, in Lithuania, the ICF principles for determining the level of working capacity are applied in a fragmentary way, and more often the biological-physical parameters of a person’s health status are used. …”
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18143
Performance evaluation and stability analysis of malt barley (Hordeum vulgare L.) varieties for yield and quality traits in Eastern Amhara, Ethiopia
Published 2021-08-01“…Mean grain yield (GY; grams of grain produced per plot, converted in kg ha−1), above ground dry biomass or biological yield (BY; dry weight of the above ground harvested biomass grams per plot, in kg ha−1) and thousand grain weight (TGW; weight of 1000 kernels, in grams) were measured on whole plots. …”
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18144
Exploration of Degradation Mechanism of Chlorogenic Acids in Stevia Based on UPLC-QTOF MS/MS
Published 2025-01-01“…Chlorogenic acids (caffeoylquinic acids, CQAs), as key bioactive components in numerous traditional herbal medicines, are highly acclaimed for their various biological activities and therapeutic benefits. Nonetheless, their stability and therapeutic utility are challenged by the propensity to degrade under various environmental stimuli, including exposure to light, temperature fluctuations, and changes in pH levels. …”
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18145
<i>Piriformospora indica</i> Enhances Rice Blast Resistance and Plant Growth
Published 2025-01-01“…In summary, these results underscore the potential of Pi as a sustainable biological control agent for rice blast disease, which is particularly beneficial for blast-susceptible rice cultivars.…”
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18146
Retrospective trend analysis of biocides in suspended particulate matter of major German rivers
Published 2025-01-01“…Abstract Background Due to their intrinsic biological activity biocides can pose an unintended threat to various aquatic organisms. …”
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18147
The Effect of Different Sulphur Sources Applied at Various Rates on Soil pH
Published 2025-01-01“…Soil pH, governed by the relative concentrations of hydrogen () and hydroxyl () ions, is a key factor affecting the chemical, physical, and biological properties of soils. Most soils in Türkiye are alkaline due to calcareous parent material and climatic influences, which restricts the availability of essential nutrients to plants. …”
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18148
Compound identification of Shuangxinfang and its potential mechanisms in the treatment of myocardial infarction with depression: insights from LC-MS/MS and bioinformatic prediction
Published 2025-01-01“…Further analysis of biological process and signaling pathways also revealed the significance of ERK/MAPK. …”
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18149
Chemopreventative potential of Salsola tuberculatiformis Botch and Compound A in the differential regulation of IL-1Ra:IL-1α in UVB exposed skin keratinocytes
Published 2025-02-01“…Purpose: The study aimed to evaluate the anti-inflammatory and anti-carcinogenic properties of S. tuberculatiformis extract and Compound A, particularly their effects on UVB-induced inflammation, cell growth parameters, and oxidative status in HaCaT cells. Methods: The biological activity of S. tuberculatiformis extract and Compound A was assessed using a cytochrome P450 assay. …”
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18150
Long-term outcome of a treat-to-target strategy in late-onset rheumatoid arthritis with chronic lung disease: 5-year results of a prospective observational study
Published 2025-02-01“…If patients exhibited no response according to the European League Against Rheumatism criteria at week 12 or had not achieved LDA by week 24, biological disease-modifying antirheumatic drugs (bDMARDs) were started targeting LDA. …”
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18151
Effects of milk extracellular vesicles from Holstein Friesian and Brown Swiss heat-stressed dairy cows on bovine mammary epithelial cells
Published 2025-02-01“…Focusing on the functioning of the mammary gland, attention has been recently paid to a new method of cell-cell communication mediated by extracellular vesicles, which with their cargo can affect the target cells' phenotypic traits, behavior, and biological functions. This study investigated whether the small extracellular vesicles (sEV) isolated from milk of heat-stressed Holstein Friesian (H) and Brown Swiss (B) cows affect the cellular response of a bovine mammary epithelial cell line (BME-UV1). …”
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18152
Establishing a new human pneumococcal standard reference serum, MPRSS-01
Published 2025-01-01“…This proposal was accepted by the Center for Biologics Evaluation and Research (CBER), enabling V116 to bridge old and new human pneumococcal reference sera.IMPORTANCEImmunogenicity of pneumococcal vaccines is measured using post-vaccination serotype-specific immunoglobulin G (IgG) antibodies in serum using enzyme-linked immunoassays with the 007sp reference serum containing serotype-specific IgG for 24 pneumococcal serotypes. …”
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18153
RETRACTED: Melanin Produced by Bordetella parapertussis Confers a Survival Advantage to the Bacterium during Host Infection
Published 2021-10-01“…The organism produces a brown pigment, the nature and biological significance of which have not been elucidated. …”
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18154
Comprehensive bioinformatics analysis identifies hub genes associated with immune cell infiltration in early-onset schizophrenia
Published 2025-01-01“…Numerous studies have demonstrated a broad link between immune dysregulation and the central nervous system in EOS, and its pathogenesis involves immune dysfunction, but the exact biological mechanisms have not been elucidated. This study employs immune infiltration analysis and bioinformatics to unveil the pathogenic mechanisms of EOS and identify potential diagnostic biomarkers, aiming for more precise clinical interventions. …”
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18155
Exploring anticancer, antioxidant, and antimicrobial potential of Aspergillus flavus, a fungal endophyte isolated from Dillenia indica leaf callus
Published 2025-02-01“…The presence of secondary metabolites in different fungal extracts were observed by FTIR and High-resolution accurate mass spectroscopy (HRAMS) methods. Different biological activities (antioxidant, antibacterial and antitumor) of fungal extracts were assessed. …”
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18156
The serum level of sclerostin decreases in radiographic axial spondyloarthritis patients with fatty lesions
Published 2025-01-01“…Results There were no significant differences between two groups in terms of gender, age, body mass index (BMI), duration, smoking, HLA-B27 positivity rate, erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), BASDAI, ASDAS-ESR, ASDAS-CRP, biological disease-modifying anti-rheumatic drugs (bDMARDs) rate. …”
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18157
The growing season of broccoli in the southern region of Dagestan
Published 2019-01-01“…Broccoli has valuable chemical composition, is a source of mineral elements, ascorbic acid, a significant amount of nitrogenous and biologically active substances, and has medicinal properties. …”
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18158
Mfsd2a suppresses colorectal cancer progression and liver metastasis via the S100A14/STAT3 axis
Published 2025-01-01“…Moreover, Kaplan-Meier analysis was used to perform survival analysis on these patients. The biological function of Mfsd2a in CRLM was confirmed by a series of experiments conducted both in vitro and in vivo. …”
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18159
Linear growth rate of vyrezub (Rutilus frisii Nordmann, 1840) in the Dnister River basin
Published 2024-12-01“…Methodology. The incomplete biological analysis was carried out directly at the sampling site, measurements were carried out according to the generally accepted method without removing fish from the water. …”
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18160
Last-millennium volcanic forcing and climate response using SO<sub>2</sub> emissions
Published 2025-01-01“…Accounting for the self-limiting effects of large sulfur dioxide (<span class="inline-formula">SO<sub>2</sub></span>) injections and the limitations in tree-ring records, such as lagged responses due to biological memory, reconciles some of the discrepancy, but uncertainties remain, particularly for the largest tropical eruptions. …”
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