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Investigating DNA Methylation of Solute Carrier Genes in Colorectal Cancer: A Comprehensive Analysis Using Microarray and Bioinformatics Tools
Published 2023-12-01“…This proposal aims to investigate the DNA methylation status of SLC genes in CRC, utilizing microarray technology and a suite of bioinformatics tools. Methods: Microarray methylation data from CRC and adjacent normal tissues underwent preprocessing, differential methylation analysis, functional enrichment exploration, and correlation analysis for a detailed study of methylation patterns. …”
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Identification of crucial extracellular genes as potential biomarkers in newly diagnosed Type 1 diabetes via integrated bioinformatics analysis
Published 2025-01-01Subjects: Get full text
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184
Exploring the mechanism of berberine treatment for atherosclerosis combined with non-alcoholic fatty liver disease based on bioinformatic and experimental study.
Published 2024-01-01“…This study investigates BBR's impact on AS and NAFLD through bioinformatics analysis and experimental models. This study utilized various bioinformatics methods, including transcriptome analysis, weighted gene co-expression network analysis (WGCNA), machine learning, and molecular docking, to identify key genes and pathways involved in AS and NAFLD. …”
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Interleukin-6 as a Pan-Cancer Prognostic Inflammatory Biomarker: A Population-Based Study and Comprehensive Bioinformatics Analysis
Published 2025-01-01Subjects: Get full text
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Construction of a circRNA-miRNA-mRNA Regulatory Network for Coronary Artery Disease by Bioinformatics Analysis
Published 2022-01-01“…The gene expression profiles of CAD were obtained from Gene Expression Omnibus datasets. Bioinformatics analysis was performed to construct a ceRNA regulatory network, from which the hub genes involved were identified through protein-protein interaction (PPI) networks leading to the identification of the circRNA-miRNA-hub gene subnetwork. …”
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Expression and prognostic value of ferritinophagy-related NCOA4 gene in low-grade glioma: integration of bioinformatics and experimental validation
Published 2025-01-01“…Methods This study comprehensively analyzed several mainstream bioinformatics databases to explore the expression, diagnostic efficacy, clinical pathological features, immune infiltration, prognostic value, and biological functions of NCOA4 in LGG. …”
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PaleAle 6.0: Prediction of Protein Relative Solvent Accessibility by Leveraging Pre-Trained Language Models (PLMs)
Published 2025-01-01Subjects: Get full text
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Protocol for reconstructing ancestral genomes from present-day samples by applying local ancestry inference
Published 2025-03-01Subjects: “…Bioinformatics…”
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Protocol for genetic analysis of population-scale ultra-low-depth sequencing data
Published 2025-03-01Subjects: “…Bioinformatics…”
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Protocol for 3D photogrammetry and morphological digitization of complex skulls
Published 2025-03-01Subjects: “…bioinformatics…”
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Modeling autoregulation of cardiac excitation-Ca-contraction and arrhythmogenic activities in response to mechanical load changes
Published 2025-02-01Subjects: Get full text
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