The Fem cell-surface signaling system is regulated by ExsA in Pseudomonas aeruginosa and affects pathogenicity by Yanqi Li, Anjali Bhagirath, Sara Badr, Pansong Zhang, Lin Chen, Maryam Dadashi, Michael G. Surette, Kangmin Duan

“…Intriguingly, the Fem system also influenced virulence factors in P. aeruginosa, including the quorum sensing systems, pyocyanin production, biofilm formation, and the type six secretion systems (T6SSs). …”
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Impacts of Pta-AckA pathway on CPS biosynthesis and type 3 fimbriae expression in Klebsiella pneumoniae by Tien-Huang Lin, Chen-Yu Wang, Chien-Chen Wu, Ching-Ting Lin

“…Their effects on AcP levels, the patterns of global acetylated protein, capsular polysaccharide (CPS) amount, serum resistance, type 3 fimbriae expression, biofilm formation, and virulence in G. mellonella larva were assessed. …”
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BTS1-knockout Saccharomyces cerevisiae with broad-spectrum antimicrobial activity through lactic acid accumulation by Liu Cong, Yuan Zhou, Yu Zhang, Shanshan Mao, Chaoqun Chen, Liying Wang, Xiao Li, Zuo Zhang, Zuobin Zhu, Ying Li

“…Additionally, it significantly impedes Escherichia coli and Staphylococcus aureus biofilm formation. Moreover, BTS1-KO S. cerevisiae exhibits low haemolytic activity, acid resistance, resistance to high bile salt concentrations, high auto-aggregation capacity and high co-aggregation capacities with pathogenic bacteria. …”
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Evaluating the dual impact of microbial activity and aged refuse layers on landfill leachate clogging: An experimental and LCA perspective by Zhaobin Li, Waifan Tang, Shulun Mak, Siukei Lam, Qingwen Li

“…Partially saturated aged refuse layers reduced clogging potential by up to 40% by stabilizing leachate chemistry and inhibiting biofilm formation. However, life cycle assessment (LCA) results indicate that while aged refuse layers mitigate clogging, they also increase the global warming potential (GWP) by 10% compared to conventional methods, highlighting the need to balance technical efficacy with environmental sustainability. …”
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Epidemiological and genetic charateristics of Vibrio vulnificus from diverse sources in China during 2012–2023 by Dongling Long, Min Li, Lingchao Ma, Jiewen Huang, Chao Lv, Yiwen Chen, Zile Cheng, Chang Liu, Huitao Huang, Xiaokui Guo, Chao Yang, Yongzhang Zhu

“…Enrichment of genes related to secretion systems and biofilm formation likely facilitated the expansion of the T6SS1-positive population. …”
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The Geographical Distribution of Global Biobanks by Farzad Parvizpour, Sarvenaz Salahi, Mohammad Amin Mahmanzar, Karim Rahimian, Neda Esfandiari, Zahra Fatahi, Niousha Khoshdast, Reyhaneh Yarmohammadi, Mohamad Amir Amirkhani, Arefeh Jafarian

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Evaluation of ampicillin plus ceftobiprole combination therapy in treating Enterococcus faecalis infective endocarditis and bloodstream infection by Simone Giuliano, Jacopo Angelini, Floriana Campanile, Paola Conti, Sarah Flammini, Alberto Pagotto, Francesco Sbrana, Luca Martini, Denise D’Elia, Mohd H. Abdul-Aziz, Menino O. Cotta, Jason A. Roberts, Robert A. Bonomo, Carlo Tascini

“…Our analysis included the study of E. faecalis biofilm production, as well as the kinetics of bacterial killing of ceftobiprole alone or in combination with ampicillin. …”
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Current trends and research advances on the application of TiO2 nanoparticles in dentistry: How far are we from clinical translation? by Hossein Mohammadi, Hedaiat Moradpoor, Salmia Beddu, Hamid Reza Mozaffari, Roohollah Sharifi, Razieh Rezaei, Nima Fallahnia, Mona Ebadi, Saiful Amri Mazlan, Mohsen Safaei

“…The present review highlights and discusses the current trends in applying TiO2 NPs in dentistry ranging from TiO2-based nanocomposite in endodontics, orthodontics, and biofilm prevention. Moreover, the potential of TiO2 NPs in developing new photodynamic therapy and the next generation of oral care products is outlined. …”
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Genomic insights into multidrug-resistant Acinetobacter baumannii strains isolated from Dhaka, Bangladesh by Sadia Ferdous, K M Shayerul Abedin Shayer, Afia Anjum, Sabbir R. Shuvo, Ishrat Jabeen, Kristi Paul Hridi, A.K.M. Imrul Hassan, Md Imran Khan, Mohammad Fazle Alam Rabbi, Mahmud Hossain, Kazi Nadim Hasan, Sohidul Islam

“…Multidrug-resistant (MDR) A. baumannii is a growing concern to the healthcare system in Bangladesh, necessitating the elucidation of the genetic characteristics of this species. Five MDR, biofilm-forming A. baumannii strains isolated from clinical samples in Dhaka, Bangladesh, underwent a comprehensive whole-genome shotgun sequencing. …”
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Development of SacB-based counterselection for efficient allelic exchange in Fusobacterium nucleatum by Peng Zhou, Bibek G C, Bo Hu, Chenggang Wu

“…Our molecular comprehension of its role in oral biofilm formation and its interactions with the host under various pathological circumstances has seen considerable advancements in recent years, primarily due to the development of various genetic tools for DNA manipulation in this bacterium. …”
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Molecular characterization of putative antibiotic resistance determinant and virulence factors genes of Acinetobacter baumannii strains isolated from intensive care unit patients i... by Faris A. Alanazi, Khalid S. Almaary, Turki M. Dawoud, Mohamed A. El-Tayeb, Yahya B. Elbadawi, Ayman S. Mubarak, Ali M. Somily

“…Conclusion: The study showed a strong relationship between virulence factors, especially biofilm formation, and antibiotic resistance.…”
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<i>Botrytis cinerea</i> PMT4 Is Involved in <i>O</i>-Glycosylation, Cell Wall Organization, Membrane Integrity, and Virulence by Verónica Plaza, Alice Pasten, Luz A. López-Ramírez, Héctor M. Mora-Montes, Julia Rubio-Astudillo, Evelyn Silva-Moreno, Luis Castillo

“…Thus, in addition to their role in glycosylation, the <i>PMT4</i> is required to virulence, biofilm formation, and membrane integrity. This study adds to our knowledge of the role of the <i>B. cinerea bcpmt4</i> gene, which is involved in glycosylation and cell biology, cell wall formation, and antifungal response.…”
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Antibacterial, Antibiofilm, and Efflux Pump Inhibitory Properties of the Crude Extract and Fractions from Acacia macrostachya Stem Bark by Akua Frema Barfour, Abraham Yeboah Mensah, Evelyn Asante-Kwatia, Cynthia Amaning Danquah, Daniel Anokwah, Silas Adjei, Michael Kwesi Baah, Merlin L. K. Mensah

“…At a concentration of 3.9–250 μg/mL, all extracts demonstrated >80% inhibition of biofilm formation in S. aureus. In P. aeruginosa, the EtOAc fraction showed the highest antibiofilm activity (59–69%) while the pet-ether fraction was most active against E. coli biofilms (45–67%). …”
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Photo-curing hyaluronic acid-Janus antibacterial packs as O2 generator precisely modulate the infectious microenvironment for antibiotic-free periodontal therapy by Runxiu Wei, Gaojie Li, Yuying Huang, Linjing Mi, Jiamin Wu, Huan Huang, Na Yin, Yuling Chen, Qiang Yang, Wenjun Zhang, Bingzhi Sun, Ran Sun, Ling Guo, Min Feng

“…In vitro studies showed that the antibacterial packs gradually released lauric acid and oxygen over 7 days, exhibiting significant anti-biofilm effects against both aerobic and anaerobic bacteria. …”
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Therapeutic Values of Earthworm Species Extract from Azad Kashmir as Anticoagulant, Antibacterial, and Antioxidant Agents by Rozina Ghulam Mustafa, Andleeb Dr Saiqa, Jorge Domínguez, Madiha Jamil, Saira Manzoor, Samna Wazir, Bushra Shaheen, Asma Parveen, Rida Khan, Shaukat Ali, Nazish Mazhar Ali, Fatima Jalal, Sadaf Azad Raja

“…The maximum zone of inhibition of E. coli was recorded as 14.66 ± 0.57 mm by A. corticis, 25.0 ± 0.0 mm by P. posthuma, 20.0 ± 0.0 mm by E. fetida, and 20.0 ± 0.0 mm by A. trapezoid. Cell proliferation, biofilm inhibition, the synergistic effect of extracts along with antibiotics, and direct bioautography supported the results of agar well diffusion assay. …”
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Effect of Zirconium Oxide and Zinc Oxide Nanoparticles on Physicochemical Properties and Antibiofilm Activity of a Calcium Silicate-Based Material by Juliane Maria Guerreiro-Tanomaru, Adinael Trindade-Junior, Bernardo Cesar Costa, Guilherme Ferreira da Silva, Leonardo Drullis Cifali, Maria Inês Basso Bernardi, Mario Tanomaru-Filho

“…Antibiofilm activity was analyzed by using direct contact test (DCT) on Enterococcus faecalis biofilm, for 5 h or 15 h. The analysis was conducted by using the number of colony-forming units (CFU/mL). …”
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Characterization and genomic insights into bacteriophages Kpph1 and Kpph9 against hypervirulent carbapenem-resistant Klebsiella pneumoniae by Ye Huang, Yuan Huang, Zhiping Wu, Ziyue Fan, Fanglin Zheng, Yang Liu, Xinping Xu

“…The phages demonstrate potent antibacterial and antibiofilm efficacy, as indicated by their capacity to inhibit biofilm formation and to disrupt established biofilms of Hv-CRKp. …”
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Association between gut microbiota and short-chain fatty acids in children with obesity by Shihan Li, Xinyu Ma, Hong Mei, Xuening Chang, Peiling He, Lingli Sun, Han Xiao, Shiqiong Wang, Ruizhen Li

“…Kyoto encyclopedia of genes and genomes (KEGG) functional analysis revealed 28 enriched KEGG pathways, of which/with the phosphotransferase system (PTS) and enhanced biofilm formation by Escherichia coli were particularly significant in the OG. …”
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Citronellol-functionalized natural silica: a biogenic approach for antifungal and antibacterial material applications by Guillermo P. Lopez, Guillermo P. Lopez, Leyanet Barberia Roque, Katerine Igal, Katerine Igal, Erasmo Gámez Espinosa, Erasmo Gámez Espinosa, Natalia Bellotti, Natalia Bellotti

“…IntroductionNew bioactive hybrid materials to prevent biofilm-induced biodeterioration are a significant challenge in indoor environments, where contaminants from microbial films compromise structural integrity and contribute to air pollution, posing health risks from prolonged exposure to biological agents.MethodsFor the first time, diatomaceous earth or diatomite (Dt) was functionalized with quaternary ammonium salt (QAS) and a biogenic compound, citronellol, to develop a bioactive hybrid material (Dt*QC). …”
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Phylogenetic analysis, metabolic profiling, and environmental adaptation of strain LCG007: a novel Rhodobacteraceae isolated from the East China Sea intertidal zone by Cuizhu Liang, Jiahua Wang, Jie Liu, Zekai Wang, Junwei Cao, Xi Yu, Li Zhang, Jiasong Fang, Jiasong Fang

“…Besides, the capacity in biofilm formation is crucial for its survival under conditions of oligotrophy or high salinity. …”
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